Pharmacology & Toxicology
Listando 39 trabajos del autor/autora 38
Lista de trabajos en el área Pharmacology & Toxicology
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42
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Article
Do specific antimicrobial stewardship interventions have an impact on carbapenem resistance in Gram-negative bacilli? A multicentre quasi-experimental ecological study: time-trend analysis and characterization of carbapenemases
Alvarez-Marin, Rocio; Lopez-Cerero, Lorena; Guerrero-Sanchez, Francisca; Palop-Borras, Begona; Dolores Rojo-Martin, Maria; Ruiz-Sancho, Andres; Herrero-Rodriguez, Carmen; Victoria Garcia, Maria; Maria Lazo-Torres, Ana; Lopez, Inmaculada; Martin-Hita, Lina;
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
0305-7453 (2021)
DOI /
10.1093/jac/dkab073
Mentions
37
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0
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1
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0
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Article
Relationship between Tolerance and Persistence Mechanisms in Acinetobacter baumannii Strains with AbkAB Toxin-Antitoxin System
Fernandez-Garcia, Laura; Fernandez-Cuenca, Felipe; Blasco, Lucia; Lopez-Rojas, Rafael; Ambroa, Anton; Lopez, Maria; Pascual, Alvaro; Bou, German; Tomas, Maria
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
0066-4804 (2018)
DOI /
10.1128/aac.00250-18
Green published, Gold other
Mentions
47
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0
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0
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Article
Development and validation of the INCREMENT-ESBL predictive score for mortality in patients with bloodstream infections due to extendedspectrum- beta-lactamase-producing Enterobacteriaceae
Raquel Palacios-Baena, Zaira; Gutierrez-Gutierrez, Belen; de Cueto, Marina; Viale, Pierluigi; Venditti, Mario; Hernandez-Torres, Alicia; Oliver, Antonio; Martinez-Martinez, Luis; Calbo, Esther; Pintado, Vicente; Gasch, Oriol; Almirante, Benito; Antonio Lep
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
0305-7453 (2017)
DOI /
10.1093/jac/dkw513
Green published, Bronze
Mentions
42
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Article
Activity of cefiderocol against high-risk clones of multidrug-resistant Enterobacterales, Acinetobacter baumannii, Pseudomonas aeruginosa and Stenotrophomonas maltophilia
Delgado-Valverde, Mercedes; del Carmen Conejo, M.; Serrano, Lara; Fernandez-Cuenca, Felipe; Pascual, Alvaro
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
0305-7453 (2020)
DOI /
10.1093/jac/dkaa117
Gold other, Green published
Mentions
2
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0
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1
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Article
Urinary Tract Conditions Affect Fosfomycin Activity against Escherichia coli Strains Harboring Chromosomal Mutations Involved in Fosfomycin Uptake
Martin-Gutierrez, G.; Docobo-Perez, F.; Rodriguez-Beltran, J.; Rodriguez-Martinez, J. M.; Aznar, J.; Pascual, A.; Blazquez, J.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
0066-4804 (2018)
DOI /
10.1128/aac.01899-17
Green published, Bronze
Mentions
2
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0
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1
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Article
Plasmidic qnr Genes Confer Clinical Resistance to Ciprofloxacin under Urinary Tract Physiological Conditions
Martin-Gutierrez, Guillermo; Manuel Rodriguez-Martinez, Jose; Pascual, Alvaro; Rodriguez-Beltran, Jeronimo; Blazquez, Jesus
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
0066-4804 (2017)
DOI /
10.1128/aac.02615-16
Bronze, Green published
Mentions
15
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Article
Enhanced Antibacterial Activity of Repurposed Mitomycin C and Imipenem in Combination with the Lytic Phage vB_KpnM-VAC13 against Clinical Isolates of Klebsiella pneumoniae
Pacios, Olga; Fernandez-Garcia, Laura; Bleriot, Ines; Blasco, Lucia; Gonzalez-Bardanca, Monica; Lopez, Maria; Fernandez-Cuenca, Felipe; Oteo, Jesus; Pascual, Alvaro; Martinez-Martinez, Luis; Domingo-Calap, Pilar; Bou, German; Tomas, Maria
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
0066-4804 (2021)
DOI /
10.1128/aac.00900-21
Mentions
10
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0
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0
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Article
Reporting antimicrobial susceptibilities and resistance phenotypes in Acinetobacter spp: a nationwide proficiency study
Fernandez-Cuenca, Felipe; Tomas, Maria; Caballero-Moyano, Francisco-Javier; Bou, German; Pascual, Alvaro
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
0305-7453 (2018)
DOI /
10.1093/jac/dkx464
Bronze
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8
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0
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0
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Article
Molecular insights into fosfomycin resistance in Escherichia coli
Ballestero-Tellez, M.; Docobo-Perez, F.; Portillo-Calderon, I.; Rodriguez-Martinez, J. M.; Racero, L.; Ramos-Guelfo, M. S.; Blazquez, J.; Rodriguez-Bano, J.; Pascual, A.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
0305-7453 (2017)
DOI /
10.1093/jac/dkw573
Bronze
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8
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0
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0
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Article
Susceptibility testing and detection of beta-lactam resistance mechanisms in Enterobacteriaceae: a multicentre national proficiency study
Diez-Aguilar, Maria; Conejo, Maria-Carmen; Morosini, Maria-Isabel; Tormo Palop, Nuria; Gimeno, Concepcion; Canton, Rafael; Pascual, Alvaro
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
0924-8579 (2018)
DOI /
10.1016/j.ijantimicag.2017.12.008
Mentions
6
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Article
Incidence and Risk Factors for Acquisition of Extended-Spectrum beta-Lactamase-Producing Enterobacteriaceae in Newborns in Seville, Spain: A Prospective Cohort Study
Jesus Rodriguez-Revuelta, Maria; Lopez-Cerero, Lorena; Serrano, Lara; Luna-Lagares, Salud; Pascual, Alvaro; Rodriguez-Bano, Jesus
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
0924-8579 (2018)
DOI /
10.1016/j.ijantimicag.2018.09.007
Mentions
10
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0
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Article
Geographical variation in therapy for bloodstream infections due to multidrug-resistant Enterobacteriaceae: a post-hoc analysis of the INCREMENT study
Harris, Patrick N. A.; Pezzani, M. Diletta; Gutierrez-Gutierrez, Belen; Viale, Pierluigi; Hsueh, Po-Ren; Ruiz-Garbajosa, Patricia; Venditti, Mario; Tumbarello, Mario; Navarro-Francisco, Carolina; Calbo, Esther; Akova, Murat; Giamarellou, Helen; Oliver, Ant
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
0924-8579 (2017)
DOI /
10.1016/j.ijantimicag.2017.08.005
Green accepted
Mentions
5
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0
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Article
MIC of amoxicillin/clavulanate according to CLSI and EUCAST: discrepancies and clinical impact in patients with bloodstream infections due to Enterobacteriaceae
Delgado-Valverde, Mercedes; Valiente-Mendez, Adoracion; Torres, Eva; Almirante, Benito; Gomez-Zorrilla, Silvia; Borrell, Nuria; Isabel Aller-Garcia, Ana; Gurgui, Mercedes; Almela, Manel; Sanz, Mercedes; Bou, German; Martinez-Martinez, Luis; Canton, Rafael;
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
0305-7453 (2017)
DOI /
10.1093/jac/dkw562
Bronze
Mentions
2
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0
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0
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1
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Article
Cost-Effectiveness Analysis of Bezlotoxumab Added to Standard of Care Versus Standard of Care Alone for the Prevention of Recurrent Clostridium difficile Infection in High-Risk Patients in Spain
Salavert, Miguel; Cobo, Javier; Pascual, Alvaro; Aragon, Belen; Maratia, Stefano; Jiang, Yiling; Aceituno, Susana; Grau, Santiago
ADVANCES IN THERAPY
0741-238X (2018)
DOI /
10.1007/s12325-018-0813-y
Green published, Gold other
Mentions
7
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0
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Article
Clinical characteristics and outcome of bacteraemia caused by Enterobacter cloacae and Klebsiella aerogenes : more similarities than differences
Alvarez-Marin, Rocio; Antonio Lepe, Jose; Gasch-Blasi, Oriol; Manuel Rodriguez-Martinez, Jose; Calvo-Montes, Jorge; Lara-Contreras, Rosario; Martin-Gandul, Cecilia; Tubau-Quintano, Fe; Eliecer Cano-Garcia, Maria; Rodriguez-Lopez, Fernando; Rodriguez-Bano,
JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE
2213-7165 (2021)
DOI /
10.1016/j.jgar.2021.04.008
Gold
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5
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0
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Article
Mechanisms of Tolerance and Resistance to Chlorhexidine in Clinical Strains ofKlebsiella pneumoniaeProducers of Carbapenemase: Role of New Type II Toxin-Antitoxin System, PemIK
Bleriot, Ines; Blasco, Lucia; Delgado-Valverde, Mercedes; Gual-de-Torrella, Ana; Ambroa, Anton; Fernandez-Garcia, Laura; Lopez, Maria; Oteo-Iglesias, Jesus; Wood, Thomas K.; Pascual, Alvaro; Bou, German; Fernandez-Cuenca, Felipe; Tomas, Maria
TOXINS
(2020)
DOI /
10.3390/toxins12090566
Gold other, Green published
Mentions
7
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0
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High incidence of MDR and XDR Pseudomonas aeruginosa isolates obtained from patients with ventilator-associated pneumonia in Greece, Italy and Spain as part of the MagicBullet clinical trial
Perez, Astrid; Gato, Eva; Perez-Llarena, Jose; Fernandez-Cuenca, Felipe; Jose Gude, Maria; Oviano, Marina; Eugenia Pachon, Maria; Garnacho, Jose; Gonzalez, Veronica; Pascual, Alvaro; Miguel Cisneros, Jose; Bou, German
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
0305-7453 (2019)
DOI /
10.1093/jac/dkz030
Bronze
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1
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0
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1
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Letter
Quantitative and automated MALDI-TOF MS-based detection of the plasmid-mediated quinolone resistance determinant AAC(6 ')-Ib-cr in Enterobacteriaceae
Oviano, Marina; Gomara, Marta; Jose Barba, Maria; Sparbier, Katrin; Pascual, Alvaro; Bou, German
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
0305-7453 (2017)
DOI /
10.1093/jac/dkx218
Bronze
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8
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0
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Article
Activity of ceftolozane/tazobactam against Pseudomonas aeruginosa and Enterobacterales isolates recovered from intensive care unit patients in Spain: The SUPERIOR multicentre study
Garcia-Fernandez, Sergio; Garcia-Castillo, Maria; Bou, German; Calvo, Jorge; Cercenado, Emilia; Delgado, Mercedes; Pitart, Cristina; Mulet, Xavier; Tormo, Nuria; Lopez Mendoza, Diego; Diaz-Reganon, Jazmin; Canton, Rafael; Oliver, Antonio; Pascual, Alvaro;
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
0924-8579 (2019)
DOI /
10.1016/j.ijantimicag.2019.02.004
Mentions
3
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Article
Contribution of hypermutation to fosfomycin heteroresistance in Escherichia coli
Portillo-Calderon, Ines; Ortiz-Padilla, Miriam; Manuel Rodriguez-Martinez, Jose; de Gregorio-Iaria, Belen; Blazquez, Jesus; Rodriguez-Bano, Jesus; Pascual, Alvaro; Docobo-Perez, Fernando
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
0305-7453 (2020)
DOI /
10.1093/jac/dkaa131
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5
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0
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Article
In vitro activity of cefiderocol and comparators against isolates of Gram-negative bacterial pathogens from a range of infection sources: SIDERO-WT-2014-2018 studies in Spain
Cercenado, Emilia; Cardenoso, Laura; Penin, Rocio; Longshaw, Christopher; Henriksen, Anne Santerre; Pascual, Alvaro
JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE
2213-7165 (2021)
DOI /
10.1016/j.jgar.2021.06.011
Gold
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6
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0
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Article
Prevalence of ST131 Clone Producing Both ESBL CTX-M-15 and AAC(6)Ib-cr Among Ciprofloxacin-Resistant Escherichia coli Isolates from Yemen
Alsharapy, Sameer Ahmed; Yanat, Betitera; Lopez-Cerero, Lorena; Nasher, Samar Saeed; Diaz-de-Alba, Paula; Pascual, Alvaro; Rodriguez-Martinez, Jose-Manuel; Touati, Abdelaziz
MICROBIAL DRUG RESISTANCE
1076-6294 (2018)
DOI /
10.1089/mdr.2018.0024
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3
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Article
OXA-48-Like-Producing Klebsiella pneumoniae in Southern Spain in 2014-2015
Machuca, Jesus; Lopez-Cerero, Lorena; Fernandez-Cuenca, Felipe; Mora-Navas, Laura; Mediavilla-Gradolph, Concepcion; Lopez-Rodriguez, Inmaculada; Pascual, Alvaro
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
0066-4804 (2019)
DOI /
10.1128/aac.01396-18
Green published, Bronze
Mentions
2
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0
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0
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Article
Molecular Characterization of Fluoroquinolone-Resistant Haemophilus parainfluenzae Clinical Isolates in Spain
Lopez-Hernandez, Inmaculada; Machuca, Jesus; Diaz de Alba, Paula; Sarvise, Carolina; Gomez, Frederic; Manuel Rodriguez-Martinez, Jose; Pascual, Alvaro
MICROBIAL DRUG RESISTANCE
1076-6294 (2017)
DOI /
10.1089/mdr.2016.0186
Mentions
2
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Article
Prevalence of Aminoglycoside-Modifying Enzymes in Escherichia coli and Klebsiella pneumoniae Producing Extended Spectrum -Lactamases Collected in Two Multicenter Studies in Spain
Fernandez-Martinez, Marta; Ruiz del Castillo, Belen; Jesus Lecea-Cuello, Maria; Rodriguez-Bano, Jesus; Pascual, Alvaro; Martinez-Martinez, Luis
MICROBIAL DRUG RESISTANCE
1076-6294 (2018)
DOI /
10.1089/mdr.2017.0102
Green published
Mentions
1
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0
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Article
Molecular topology: A new strategy for antimicrobial resistance control
Zanni, Riccardo; Galvez-Llompart, Maria; Machuca, Jesus; Garcia-Domenech, Ramon; Recacha, Esther; Pascual, Alvaro; Manuel Rodriguez-Martinez, Jose; Galvez, Jorge
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
0223-5234 (2017)
DOI /
10.1016/j.ejmech.2017.05.055
Mentions
1
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0
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0
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0
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Article
Characterization of Plasmid-Mediated Quinolone Resistance Determinants in High-Level Quinolone-Resistant Enterobacteriaceae Isolates from the Community: First Report of qnrD Gene in Algeria
Yanat, Betitera; Machuca, Jesus; Diaz-de-Alba, Paula; Mezhoud, Halima; Touati, Abdelaziz; Pascual, Alvaro; Rodriguez-Martinez, Jose-Manuel
MICROBIAL DRUG RESISTANCE
1076-6294 (2017)
DOI /
10.1089/mdr.2016.0031
Mentions
1
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0
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0
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0
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Article
Reporting antimicrobial susceptibilities and resistance phenotypes in Staphylococcus spp.: a nationwide proficiency study
Fernandez-Cuenca, Felipe; Lopez-Hernandez, Inmaculada; Cercenado, Emilia; Conejo, Carmen; Tormo, Nuria; Gimeno, Concha; Pascual, Alvaro
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
0305-7453 (2021)
DOI /
10.1093/jac/dkab017
Mentions
1
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0
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Article
Cytotoxic Effect Associated with Overexpression of QNR Proteins in Escherichia coli
Machuca, Jesus; Diaz de Alba, Paula; Recacha, Esther; Pascual, Alvaro; Manuel Rodriguez-Martinez, Jose
MICROBIAL DRUG RESISTANCE
1076-6294 (2017)
DOI /
10.1089/mdr.2016.0245
Mentions
1
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0
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0
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Article
Occurrence of the Plasmid-Mediated Fluoroquinolone Resistance qepA1 Gene in Two Clonal Clinical Isolates of CTX-M-15-Producing Escherichia coli from Algeria
Yanat, Betitera; Yahia, Radia Dali; Yazi, Leila; Machuca, Jesus; Diaz-de-Alba, Paula; Touati, Abdelaziz; Pascual, Alvaro; Rodriguez-Martinez, Jose-Manuel
MICROBIAL DRUG RESISTANCE
1076-6294 (2017)
DOI /
10.1089/mdr.2016.0135
Mentions
3
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0
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0
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Article
Bacteraemia due to non-ESBL-producing Escherichia coli O25b:H4 sequence type 131: insights into risk factors, clinical features and outcomes
Morales-Barroso, Isabel; Lopez-Cerero, Lorena; Molina, Jose; Bellido, Mar; Dolores Navarro, Maria; Serrano, Lara; Gonzalez-Galan, Veronica; Praena, Julia; Pascual, Alvaro; Rodriguez-Bano, Jesus
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
0924-8579 (2017)
DOI /
10.1016/j.ijantimicag.2016.12.013
Mentions
2
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0
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Article
Intestinal colonization due to Escherichia coli ST131: risk factors and prevalence
Morales Barroso, Isabel; Lopez-Cerero, Lorena; Dolores Navarro, Maria; Gutierrez-Gutierrez, Belen; Pascual, Alvaro; Rodriguez-Bano, Jesus
ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL
2047-2994 (2018)
DOI /
10.1186/s13756-018-0427-9
Gold DOAJ, Green published
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2
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0
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Article
Suppression of the SOS response modifies spatiotemporal evolution, post-antibiotic effect, bacterial fitness and biofilm formation in quinolone-resistant Escherichia coli
Recacha, E.; Machuca, J.; Diaz-Diaz, S.; Garcia-Duque, A.; Ramos-Guelfo, M.; Docobo-Perez, F.; Blazquez, J.; Pascual, A.; Rodriguez-Martinez, J. M.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
0305-7453 (2019)
DOI /
10.1093/jac/dky407
Bronze
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1
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Article
Interplay among Different Fosfomycin Resistance Mechanisms in Klebsiella pneumoniae
Ortiz-Padilla, M.; De Gregorio-Iaria, B.; Blazquez, J.; Rodriguez-Bano, J.; Pascual, A.; Rodriguez-Martinez, J. M.; Docobo-Perez, F.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
0066-4804 (2021)
DOI /
10.1128/aac.01911-20
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1
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Extended-spectrum beta-lactamase-producing Enterobacteriaceae from animal origin and wastewater in Tunisia: first detection of O25b-B2(3)-CTX-M-27-ST131 Escherichia coli and CTX-M-15/OXA-204-producing Citrobacter freundii from wastewater
Sghaier, Senda; Abbassi, Mohamed Salah; Pascual, Alvaro; Serrano, Lara; Diaz-de-Alba, Paula; Ben Said, Meriam; Hassen, Bilel; Ibrahim, Chourouk; Hassen, Abdennaceur; Lopez-Cerero, Lorena
JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE
2213-7165 (2019)
DOI /
10.1016/j.jgar.2019.01.002
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1
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Role of low-level quinolone resistance in generating tolerance in Escherichia coli under therapeutic concentrations of ciprofloxacin
Ortiz-Padilla, M.; Diaz-Diaz, S.; Machuca, J.; Tejada-Gonzalez, A.; Recacha, E.; Docobo-Perez, F.; Pascual, A.; Rodriguez-Martinez, J. M.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
0305-7453 (2020)
DOI /
10.1093/jac/dkaa151
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1
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Activity of Fosfomycin and Amikacin against Fosfomycin-Heteroresistant Escherichia coli Strains in a Hollow-Fiber Infection Model
Ortiz-Padilla, M.; De Gregorio-Iaria, B.; Blazquez, J.; Rodriguez-Bano, J.; Rodriguez-Martinez, J. M.; Pascual, A.; Docobo-Perez, F.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
0066-4804 (2021)
DOI /
10.1128/aac.02213-20
Green published
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1
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Effect of RecA inactivation on quinolone susceptibility and the evolution of resistance in clinical isolates of Escherichia coli
Machuca, J.; Recacha, E.; Gallego-Mesa, B.; Diaz-Diaz, S.; Rojas-Granado, G.; Garcia-Duque, A.; Docobo-Perez, F.; Blazquez, J.; Rodriguez-Rojas, A.; Pascual, A.; Rodriguez-Martinez, J. M.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
0305-7453 (2021)
DOI /
10.1093/jac/dkaa448
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1
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Population Pharmacokinetics of Piperacillin in Non-Critically Ill Patients with Bacteremia Caused by Enterobacteriaceae
Merino-Bohorquez, Vicente; Docobo-Perez, Fernando; Valiente-Mendez, Adoracion; Delgado-Valverde, Mercedes; Camean, Manuel; Hope, William W.; Pascual, Alvaro; Rodriguez-Bano, Jesus
ANTIBIOTICS-BASEL
2079-6382 (2021)
DOI /
10.3390/antibiotics10040348
Gold DOAJ, Green published
