Biology & Biochemistry
Listando 16 trabajos del autor/autora 38
Lista de trabajos en el área Biology & Biochemistry
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696
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14
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Article
Na(+)controls hypoxic signalling by the mitochondrial respiratory chain
Hernansanz-Agustin, Pablo; Choya-Foces, Carmen; Carregal-Romero, Susana; Ramos, Elena; Oliva, Tamara; Villa-Pina, Tamara; Moreno, Laura; Izquierdo-Alvarez, Alicia; Cabrera-Garcia, J. Daniel; Cortes, Ana; Lechuga-Vieco, Ana Victoria; Jadiya, Pooja; Navarro,
NATURE
0028-0836 (2020)
DOI /
10.1038/s41586-020-2551-y
Green published, Green accepted
Mentions
65
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0
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23
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0
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Article
Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice
Caballero, Benjamin; Bourdenx, Mathieu; Luengo, Enrique; Diaz, Antonio; Sohn, Peter Dongmin; Chen, XU; Wang, Chao; Juste, Yves R.; Wegmann, Susanne; Patel, Bindi; Young, Zapporah T.; Kuo, Szu Yu; Rodriguez-Navarro, Jose Antonio; Shao, Hao; Lopez, Manuela G
NATURE COMMUNICATIONS
(2021)
DOI /
10.1038/s41467-021-22501-9
Green published, Gold
Mentions
13
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0
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4
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0
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Article
NOX4-dependent neuronal autotoxicity and BBB breakdown explain the superior sensitivity of the brain to ischemic damage
Casas, Ana I.; Geuss, Eva; Kleikers, Pamela W. M.; Mencl, Stine; Herrmann, Alexander M.; Buendia, Izaskun; Egea, Javier; Meuth, Sven G.; Lopez, Manuela G.; Kleinschnitz, Christoph; Schmidt, Harald H. H. W.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
0027-8424 (2017)
DOI /
10.1073/pnas.1705034114
Green published, Hybrid
Mentions
4
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0
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1
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Article
Pharmacological doses of melatonin impede cognitive decline in tau-related Alzheimer models, once tauopathy is initiated, by restoring the autophagic flux
Luengo, Enrique; Buendia, Izaskun; Fernandez-Mendivil, Cristina; Trigo-Alonso, Paula; Negredo, Pilar; Michalska, Patrycja; Hernandez-Garcia, Borja; Sanchez-Ramos, Cristina; Bernal, Juan A.; Ikezu, Tsuneya; Leon, Rafael; Lopez, Manuela G.
JOURNAL OF PINEAL RESEARCH
0742-3098 (2019)
DOI /
10.1111/jpi.12578
Mentions
12
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0
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1
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Discovery of the first dual GSK3 beta inhibitor/Nrf2 inducer. A new multitarget therapeutic strategy for Alzheimer's disease
Gameiro, Isabel; Michalska, Patrycja; Tenti, Giammarco; Cores, Angel; Buendia, Izaskun; Rojo, Ana I.; Georgakopoulos, Nikolaos D.; Hernandez-Guijo, Jesus M.; Teresa Ramos, Maria; Wells, Geoffrey; Lopez, Manuela G.; Cuadrado, Antonio; Carlos Menendez, J.; L
SCIENTIFIC REPORTS
2045-2322 (2017)
DOI /
10.1038/srep45701
Gold DOAJ, Green published
Mentions
3
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0
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1
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0
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Article
Aging and Progression of Beta-Amyloid Pathology in Alzheimer's Disease Correlates with Microglial Heme-Oxygenase-1 Overexpression
Fernandez-Mendivil, Cristina; Arreola, Miguel A.; Hohsfield, Lindsay A.; Green, Kim N.; Lopez, Manuela G.
ANTIOXIDANTS
(2020)
DOI /
10.3390/antiox9070644
Gold, Green published
Mentions
15
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0
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0
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Article
From single drug targets to synergistic network pharmacology in ischemic stroke
Casas, Ana I.; Hassan, Ahmed A.; Larsen, Simon J.; Gomez-Rangel, Vanessa; Elbatreek, Mahmoud; Kleikers, Pamela W. M.; Guney, Emre; Egea, Javier; Lopez, Manuela G.; Baumbach, Jan; Schmidt, Harald H. H. W.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
0027-8424 (2019)
DOI /
10.1073/pnas.1820799116
Green published, Hybrid
Mentions
1
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0
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1
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0
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Article
Antioxidant, Anti-inflammatory and Neuroprotective Profiles of Novel 1,4-Dihydropyridine Derivatives for the Treatment of Alzheimer's Disease
Michalska, Patrycja; Mayo, Paloma; Fernandez-Mendivil, Cristina; Tenti, Giammarco; Duarte, Pablo; Buendia, Izaskun; Teresa Ramos, Maria; Lopez, Manuela G.; Carlos Menendez, J.; Leon, Rafael
ANTIOXIDANTS
(2020)
DOI /
10.3390/antiox9080650
Gold DOAJ, Green published
Mentions
2
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0
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1
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0
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Article
Deficiency in the transcription factor NRF2 worsens inflammatory parameters in a mouse model with combined tauopathy and amyloidopathy
Rojo, Ana, I; Pajares, Marta; Garcia-Yague, Angel J.; Buendia, Izaskun; Van Leuven, Fred; Yamamoto, Masayuki; Lopez, Manuela G.; Cuadrado, Antonio
REDOX BIOLOGY
2213-2317 (2018)
DOI /
10.1016/j.redox.2018.07.006
Gold, Green published
Mentions
1
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0
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1
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0
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Article
Neuroprotective effects of EpoL against oxidative stress induced by soluble oligomers of A beta peptide
Castillo, C.; Fernandez-Mendivil, C.; Buendia, I; Saavedra, P.; Meza, C.; Parra, N. C.; Lopez, M. G.; Toledo, J. R.; Fuentealba, J.
REDOX BIOLOGY
2213-2317 (2019)
DOI /
10.1016/j.redox.2019.101187
Gold DOAJ, Green published
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0
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0
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1
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Article
Heme-Oxygenase I and PCG-1 alpha Regulate Mitochondrial Biogenesis via Microglial Activation of Alpha7 Nicotinic Acetylcholine Receptors Using PNU282987
Navarro, Elisa; Gonzalez-Lafuente, Laura; Perez-Liebana, Irene; Buendia, Izaskun; Lopez-Bernardo, Elia; Sanchez-Ramos, Cristina; Prieto, Ignacio; Cuadrado, Antonio; Satrustegui, Jorgina; Cadenas, Susana; Monsalve, Maria; Lopez, Manuela G.
ANTIOXIDANTS & REDOX SIGNALING
1523-0864 (2017)
DOI /
10.1089/ars.2016.6698
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0
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0
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1
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1-(2 ',5 '-Dihydroxyphenyl)-3-(2-fluoro-4-hydroxyphenyl)-1-propanone (RGM079): A Positive Allosteric Modulator of alpha 7 Nicotinic Receptors with Analgesic and Neuroprotective Activity
Perez de Vega, Maria Jesus; Fernandez-Mendivil, Cristina; de la Torre Martinez, Roberto; Gonzalez-Rodriguez, Sara; Mullet, Jose; Sala, Francisco; Sala, Salvador; Criado, Manuel; Moreno-Fernandez, Silvia; Miguel, Marta; Fernandez-Carvajal, Asia; Ferrer-Mont
ACS CHEMICAL NEUROSCIENCE
1948-7193 (2019)
DOI /
10.1021/acschemneuro.9b00364
Mentions
4
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0
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0
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0
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Article
Mitochondrial complex I deactivation is related to superoxide production in acute hypoxia
Hernansanz-Agustin, Pablo; Ramos, Elena; Navarro, Elisa; Parada, Esther; Sanchez-Lopez, Nuria; Pelaez-Aguado, Laura; Daniel Cabrera-Garcia, J.; Tello, Daniel; Buendia, Izaskun; Marina, Anabel; Egea, Javier; Lopez, Manuela G.; Bogdanova, Anna; Martinez-Ruiz
REDOX BIOLOGY
2213-2317 (2017)
DOI /
10.1016/j.redox.2017.04.025
Gold DOAJ, Green published, Green accepted
Mentions
3
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0
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0
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Article
Neuroprotective effect of a new variant of Epo nonhematopoietic against oxidative stress
Castillo, C.; Zaror, S.; Gonzalez, M.; Hidalgo, A.; Burgos, C. F.; Cabezas, O. I.; Hugues, F.; Jimenez, S. P.; Gonzalez-Horta, E.; Gonzalez-Chavarria, I.; Gavilan, J.; Montesino, R.; Sanchez, O.; Lopez, Manuela G.; Fuentealba, J.; Toledo, J. R.
REDOX BIOLOGY
2213-2317 (2018)
DOI /
10.1016/j.redox.2017.09.010
Gold DOAJ, Green published
Mentions
2
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0
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0
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0
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Article
Protective role of microglial HO-1 blockade in aging: Implication of iron metabolism
Fernandez-Mendivil, Cristina; Luengo, Enrique; Trigo-Alonso, Paula; Garcia-Magro, Nuria; Negredo, Pilar; Lopez, Manuela G.
REDOX BIOLOGY
2213-2317 (2021)
DOI /
10.1016/j.redox.2020.101789
Gold, Green published
Mentions
5
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0
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0
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Article
The APPswe/PS1A246E mutations in an astrocytic cell line leads to increased vulnerability to oxygen and glucose deprivation, Ca2+ dysregulation, and mitochondrial abnormalities
Dolores Martin-de-Saavedra, Maria; Navarro, Elisa; Moreno-Ortega, Ana J.; Cunha, Mauricio P.; Buendia, Izaskun; Hernansanz-Agustin, Pablo; Leon, Rafael; Cano-Abad, Maria F.; Martinez-Ruiz, Antonio; Martinez-Murillo, Ricardo; Duchen, Michael R.; Lopez, Manu
JOURNAL OF NEUROCHEMISTRY
0022-3042 (2018)
DOI /
10.1111/jnc.14293
Bronze