Pharmacology & Toxicology
Listando 46 trabajos del autor/autora 38
Lista de trabajos en el área Pharmacology & Toxicology
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Type 1 Diabetes Mellitus reversal via implantation of magnetically purified microencapsulated pseudoislets
Espona-Noguera, A.; Etxebarria-Elezgarai, J.; Saenz del Burgo, L.; Canibano-Hernandez, A.; Gurruchaga, H.; Blanco, F. J.; Orive, G.; Hernandez, Rosa M.; Benito-Lopez, F.; Ciriza, J.; Basabe-Desmonts, L.; Pedraz, J. L.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
0378-5173 (2019)
DOI /
10.1016/j.ijpharm.2019.01.058
Green published
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1
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0
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4
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0
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Article
Non-viral vectors based on cationic niosomes as efficient gene delivery vehicles to central nervous system cells into the brain
Mashal, Mohamed; Attia, Noha; Soto-Sanchez, Cristina; Martinez-Navarrete, Gema; Fernandez, Eduardo; Puras, Gustavo; Pedraz, Jose Luis
INTERNATIONAL JOURNAL OF PHARMACEUTICS
0378-5173 (2018)
DOI /
10.1016/j.ijpharm.2018.09.038
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47
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Cell microencapsulation technologies for sustained drug delivery: Latest advances in efficacy and biosafety
Lopez-Mendez, Tania B.; Santos-Vizcaino, Edorta; Luis Pedraz, Jose; Orive, Gorka; Maria Hernandez, Rosa
JOURNAL OF CONTROLLED RELEASE
0168-3659 (2021)
DOI /
10.1016/j.jconrel.2021.06.006
Hybrid, Green published
Mentions
30
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Cell microencapsulation technologies for sustained drug delivery: Clinical trials and companies
Lopez-Mendez, Tania B.; Santos-Vizcaino, Edorta; Luis Pedraz, Jose; Maria Hernandez, Rosa; Orive, Gorka
DRUG DISCOVERY TODAY
1359-6446 (2021)
DOI /
10.1016/j.drudis.2020.11.019
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1
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2
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Pharmacokinetics of Benznidazole in Healthy Volunteers and Implications in Future Clinical Trials
Molina, I.; Salvador, F.; Sanchez-Montalva, A.; Artaza, M. A.; Moreno, R.; Perin, L.; Esquisabel, A.; Pinto, L.; Pedraz, J. L.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
0066-4804 (2017)
DOI /
10.1128/aac.01912-16
Bronze, Green published
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13
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0
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Intrapericardial Delivery of APA-Microcapsules as Promising Stem Cell Therapy Carriers in an Experimental Acute Myocardial Infarction Model
Baez-Diaz, Claudia; Blanco-Blazquez, Virginia; Sanchez-Margallo, Francisco Miguel; Lopez, Esther; Martin, Helena; Espona-Noguera, Albert; Casado, Javier G.; Ciriza, Jesus; Luis Pedraz, Jose; Crisostomo, Veronica
PHARMACEUTICS
(2021)
DOI /
10.3390/pharmaceutics13111824
Green published, Gold
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9
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Benefits of cryopreservation as long-term storage method of encapsulated cardiosphere-derived cells for cardiac therapy: A biomechanical analysis
Paz-Artigas, Laura; Ziani, Kaoutar; Alcaine, Clara; Baez-Diaz, Claudia; Blanco-Blazquez, Virginia; Pedraz, Jose Luis; Ochoa, Ignacio; Ciriza, Jesus
INTERNATIONAL JOURNAL OF PHARMACEUTICS
0378-5173 (2021)
DOI /
10.1016/j.ijpharm.2021.121014
Hybrid, Green published
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7
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Modulation of Conductivity of Alginate Hydrogels Containing Reduced Graphene Oxide through the Addition of Proteins
Raslan, Ahmed; Ciriza, Jesus; Ochoa de Retana, Ana Maria; Sanjuan, Maria Luisa; Toprak, Muhammet S.; Galvez-Martin, Patricia; Saenz-del-Burgo, Laura; Pedraz, Jose Luis
PHARMACEUTICS
(2021)
DOI /
10.3390/pharmaceutics13091473
Green published, Gold
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11
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0
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0
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Tendon tissue engineering: Cells, growth factors, scaffolds and production techniques
Ruiz-Alonso, Sandra; Lafuente-Merchan, Markel; Ciriza, Jesus; Saenz-del-Burgo, Laura; Luis Pedraz, Jose
JOURNAL OF CONTROLLED RELEASE
0168-3659 (2021)
DOI /
10.1016/j.jconrel.2021.03.040
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10
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3D printed polyamide macroencapsulation devices combined with alginate hydrogels for insulin-producing cell-based therapies
Espona-Noguera, Albert; Ciriza, Jesus; Canibano-Hernandez, Alberto; Villa, Rosa; Saenz del Burgo, Laura; Alvarez, Mar; Luis Pedraz, Jose
INTERNATIONAL JOURNAL OF PHARMACEUTICS
0378-5173 (2019)
DOI /
10.1016/j.ijpharm.2019.06.009
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11
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Gene delivery to the rat retina by non-viral vectors based on chloroquine-containing cationic niosomes
Mashal, Mohamed; Attia, Noha; Martinez-Navarrete, Gema; Soto-Sanchez, Cristina; Fernandez, Eduardo; Grijalvo, Santiago; Eritja, Ramon; Puras, Gustavo; Luis Pedraz, Jose
JOURNAL OF CONTROLLED RELEASE
0168-3659 (2019)
DOI /
10.1016/j.jconrel.2019.05.010
Green submitted
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8
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Article
Oral delivery of oleuropein-loaded lipid nanocarriers alleviates inflammation and oxidative stress in acute colitis
Huguet-Casquero, Amaia; Xu, Yining; Gainza, Eusebio; Luis Pedraz, Jose; Beloqui, Ana
INTERNATIONAL JOURNAL OF PHARMACEUTICS
0378-5173 (2020)
DOI /
10.1016/j.ijpharm.2020.119515
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5
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Characterization of encapsulated porcine cardiosphere-derived cells embedded in 3D alginate matrices
Ziani, Kaoutar; Espona-Noguera, Albert; Crisostomo, Veronica; Casado, Javier G.; Sanchez-Margallo, Francisco M.; Saenz-del-Burgo, Laura; Ciriza, Jesus; Luis Pedraz, Jose
INTERNATIONAL JOURNAL OF PHARMACEUTICS
0378-5173 (2021)
DOI /
10.1016/j.ijpharm.2021.120454
Gold other, Green published
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1
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0
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0
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Graphene oxide and reduced graphene oxide-based scaffolds in regenerative medicine
Raslan, Ahmed; Saenz del Burgo, Laura; Ciriza, Jesus; Luis Pedraz, Jose
INTERNATIONAL JOURNAL OF PHARMACEUTICS
0378-5173 (2020)
DOI /
10.1016/j.ijpharm.2020.119226
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0
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Non-viral vectors based on magnetoplexes, lipoplexes and polyplexes for VEGF gene delivery into central nervous system cells
Villate-Beitia, Ilia; Puras, Gustavo; Soto-Sanchez, Cristina; Agirre, Mireia; Ojeda, Edilberto; Zarate, Jon; Fernandez, Eduardo; Luis Pedraz, Jose
INTERNATIONAL JOURNAL OF PHARMACEUTICS
0378-5173 (2017)
DOI /
10.1016/j.ijpharm.2017.02.016
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6
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Correlation between Biophysical Properties of Niosomes Elaborated with Chloroquine and Different Tensioactives and Their Transfection Efficiency
Sainz-Ramos, Myriam; Villate-Beitia, Ilia; Gallego, Idoia; AL Qtaish, Nuseibah; Menendez, Margarita; Lagartera, Laura; Grijalvo, Santiago; Eritja, Ramon; Puras, Gustavo; Pedraz, Jose Luis
PHARMACEUTICS
(2021)
DOI /
10.3390/pharmaceutics13111787
Gold, Green published
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4
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Brain Angiogenesis Induced by Nonviral Gene Therapy with Potential Therapeutic Benefits for Central Nervous System Diseases
Gallego, Idoia; Villate-Beitia, Ilia; Soto-Sanchez, Cristina; Menendez, Margarita; Grijalvo, Santiago; Eritja, Ramon; Martinez-Navarrete, Gema; Humphreys, Lawrence; Lopez Mendez, Tania Belen; Puras, Gustavo; Fernandez, Eduardo; Luis Pedraz, Jose
MOLECULAR PHARMACEUTICS
1543-8384 (2020)
DOI /
10.1021/acs.molpharmaceut.9b01213
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3
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Retinal gene delivery enhancement by lycopene incorporation into cationic niosomes based on DOTMA and polysorbate 60
Mashal, Mohamed; Attia, Noha; Puras, Gustavo; Martinez-Navarrete, Gema; Fernandez, Eduardo; Luis Pedraz, Jose
JOURNAL OF CONTROLLED RELEASE
0168-3659 (2017)
DOI /
10.1016/j.jconrel.2017.03.386
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3
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Sorbitol-penetration enhancer containing vesicles loaded with baicalin for the protection and regeneration of skin injured by oxidative stress and UV radiation
Manca, Maria Letizia; Mir-Palomo, Silvia; Caddeo, Carla; Nacher, Amparo; Diez-Sales, Octavio; Peris, Jose Esteban; Pedraz, Jose Luis; Fadda, Anna Maria; Manconi, Maria
INTERNATIONAL JOURNAL OF PHARMACEUTICS
0378-5173 (2019)
DOI /
10.1016/j.ijpharm.2018.11.053
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2
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Nasal Spray Formulations Based on Combined Hyalurosomes and Glycerosomes Loading Zingiber officinalis Extract as Green and Natural Strategy for the Treatment of Rhinitis and Rhinosinusitis
Casula, Eleonora; Manca, Maria Letizia; Perra, Matteo; Pedraz, Jose Luis; Lopez-Mendez, Tania Belen; Lozano, Antonio; Calvo, Esteban; Zaru, Marco; Manconi, Maria
ANTIOXIDANTS
(2021)
DOI /
10.3390/antiox10071109
Gold, Green published
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2
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0
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Mesenchymal Stem Cells as a Gene Delivery Tool: Promise, Problems, and Prospects
Attia, Noha; Mashal, Mohamed; Puras, Gustavo; Pedraz, Jose Luis
PHARMACEUTICS
(2021)
DOI /
10.3390/pharmaceutics13060843
Gold DOAJ, Green published
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2
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Extraction, Characterization and Incorporation of Hypericum scruglii Extract in Ad Hoc Formulated Phospholipid Vesicles Designed for the Treatment of Skin Diseases Connected with Oxidative Stress
Allaw, Mohamad; Manconi, Maria; Aroffu, Matteo; Marongiu, Francesca; Porceddu, Marco; Bacchetta, Gianluigi; Usach, Iris; Rached, Rita Abi; Rajha, Hiba N.; Maroun, Richard G.; Pedraz, Jose Luis; Lopez-Mendez, Tania B.; Fadda, Anna Maria; Manca, Maria Letizi
PHARMACEUTICS
(2020)
DOI /
10.3390/pharmaceutics12111010
Gold DOAJ, Green published
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3
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Current Insights into 3D Bioprinting: An Advanced Approach for Eye Tissue Regeneration
Ruiz-Alonso, Sandra; Villate-Beitia, Ilia; Gallego, Idoia; Lafuente-Merchan, Markel; Puras, Gustavo; Saenz-del-Burgo, Laura; Pedraz, Jose Luis
PHARMACEUTICS
(2021)
DOI /
10.3390/pharmaceutics13030308
Green published, Gold
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4
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Hyaluronic Acid Promotes Differentiation of Mesenchymal Stem Cells from Different Sources toward Pancreatic Progenitors within Three-Dimensional Alginate Matrixes
Canibano-Hernandez, Alberto; Saenz del Burgo, Laura; Espona-Noguera, Albert; Orive, Gorka; Hernandez, Rosa M.; Ciriza, Jesus; Luis Pedraz, Jose
MOLECULAR PHARMACEUTICS
1543-8384 (2019)
DOI /
10.1021/acs.molpharmaceut.8b01126
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4
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Cationic Niosomes as Non-Viral Vehicles for Nucleic Acids: Challenges and Opportunities in Gene Delivery
Grijalvo, Santiago; Puras, Gustavo; Zarate, Jon; Sainz-Ramos, Myriam; Qtaish, Nuseibah A. L.; Lopez, Tania; Mashal, Mohamed; Attia, Noha; Diaz Diaz, David; Pons, Ramon; Fernandez, Eduardo; Luis Pedraz, Jose; Eritja, Ramon
PHARMACEUTICS
(2019)
DOI /
10.3390/pharmaceutics11020050
Green published, Gold, Green submitted
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2
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Design and characterization of a magnetite/PEI multifunctional nanohybrid as non-viral vector and cell isolation system
Megias, Raul; Arco, Maialen; Ciriza, Jesus; Saenz del Burgo, Laura; Puras, Gustavo; Lopez-Viota, Margarita; Delgado, Angel V.; Dobson, Jon P.; Arias, Jose L.; Pedraz, Jose L.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
0378-5173 (2017)
DOI /
10.1016/j.ijpharm.2016.12.042
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2
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Polysorbate 20 non-ionic surfactant enhances retinal gene delivery efficiency of cationic niosomes after intravitreal and subretinal administration
Villate-Beitia, Ilia; Gallego, Idoia; Martinez-Navarrete, Gema; Zarate, Jon; Lopez-Mendez, Tania; Soto-Sanchez, Cristina; Santos-Vizcaino, Edorta; Puras, Gustavo; Fernandez, Eduardo; Luis Pedraz, Jose
INTERNATIONAL JOURNAL OF PHARMACEUTICS
0378-5173 (2018)
DOI /
10.1016/j.ijpharm.2018.07.035
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2
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Sphingolipid extracts enhance gene delivery of cationic lipid vesicles into retina and brain
AL Qtaish, Nuseibah; Gallego, Idoia; Beitia, Ilia Villate-; Sainz-Ramos, Myriam; Martinez-Navarrete, Gema; Soto-Sanchez, Cristina; Fernandez, Eduardo; Galvez-Martin, Patricia; Lopez-Mendez, Tania B.; Puras, Gustavo; Pedraz, Jose Luis
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
0939-6411 (2021)
DOI /
10.1016/j.ejpb.2021.09.011
Hybrid
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2
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Excipient-Free Inhalable Microparticles of Azithromycin Produced by Electrospray: A Novel Approach to Direct Pulmonary Delivery of Antibiotics
Arauzo, Beatriz; Lopez-Mendez, Tania B.; Lobera, Maria Pilar; Calzada-Funes, Javier; Pedraz, Jose Luis; Santamaria, Jesus
PHARMACEUTICS
(2021)
DOI /
10.3390/pharmaceutics13121988
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2
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Determination of the spatiotemporal dependence of Pseudomonas aeruginosa biofilm viability after treatment with NLC- colistin
Sans-Serramitjana, Ulalia; Jorba, Marta; Luis Pedraz, Jose; Vinuesa, Teresa; Vinas, Miguel
INTERNATIONAL JOURNAL OF NANOMEDICINE
1178-2013 (2017)
DOI /
10.2147/ijn.s138763
Green published, Gold, Green submitted
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2
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Hyaluronic acid enhances cell survival of encapsulated insulin-producing cells in alginate-based microcapsules
Canibano-Hernandez, Alberto; Saenz del Burgo, Laura; Espona-Noguera, Albert; Orive, Gorka; Ma Hernandez, Rosa; Ciriza, Jesus; Luis Pedraz, Jose
INTERNATIONAL JOURNAL OF PHARMACEUTICS
0378-5173 (2019)
DOI /
10.1016/j.ijpharm.2018.12.062
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1
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Improved control over MSCs behavior within 3D matrices by using different cell loads in both in vitro and in vivo environments
Belen Lopez-Mendez, Tania; Santos-Vizcaino, Edorta; Javier Blanco, Francisco; Luis Pedraz, Jose; Maria Hernandez, Rosa; Orive, Gorka
INTERNATIONAL JOURNAL OF PHARMACEUTICS
0378-5173 (2017)
DOI /
10.1016/j.ijpharm.2017.09.014
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1
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From process effluents to intestinal health promotion: Developing biopolymer-whey liposomes loaded with gingerol to heal intestinal wounds and neutralize oxidative stress
Rezvani, Maryam; Manca, Maria Letizia; Muntoni, Aldo; De Gioannis, Giorgia; Luis Pedraz, Jose; Gutierrez, Gemma; Matos, Maria; Fadda, Anna Maria; Manconi, Maria
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2021)
DOI /
10.1016/j.ijpharm.2021.121389
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1
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Gene delivery to the lungs: pulmonary gene therapy for cystic fibrosis
Villate-Beitia, Ilia; Zarate, Jon; Puras, Gustavo; Luis Pedraz, Jose
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
0363-9045 (2017)
DOI /
10.1080/03639045.2017.1298122
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1
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Current advanced therapy cell-based medicinal products for type-1-diabetes treatment
Canibano-Hernandez, Alberto; Saenz del Burgo, Laura; Espona-Noguera, Albert; Ciriza, Jesus; Luis Pedraz, Jose
INTERNATIONAL JOURNAL OF PHARMACEUTICS
0378-5173 (2018)
DOI /
10.1016/j.ijpharm.2018.03.041
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1
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Editorial Material
The Role of Lipid Nanoparticles and its Surface Modification in Reaching the Brain: An Approach for Neurodegenerative Diseases Treatment
Hernando, Sara; Luis Pedraz, Jose; Igartua, Manoli; Maria Hernandez, Rosa
CURRENT DRUG DELIVERY
1567-2018 (2018)
DOI /
10.2174/1567201815666180510103747
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1
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Gene transfer to rat cerebral cortex mediated by polysorbate 80 and poloxamer 188 nonionic surfactant vesicles
Attia, Noha; Mashal, Mohamed; Soto-Sanchez, Cristina; Martinez-Navarrete, Gema; Fernandez, Eduardo; Grijalvo, Santiago; Eritja, Ramon; Puras, Gustavo; Luis Pedraz, Jose
DRUG DESIGN DEVELOPMENT AND THERAPY
1177-8881 (2018)
DOI /
10.2147/dddt.s178532
Gold, Green submitted, Green published
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3
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Review of Advanced Hydrogel-Based Cell Encapsulation Systems for Insulin Delivery in Type 1 Diabetes Mellitus
Espona-Noguera, Albert; Ciriza, Jesus; Canibano-Hernandez, Alberto; Orive, Gorka; Maria Hernandez, Rosa; Saenz del Burgo, Laura; Luis Pedraz, Jose
PHARMACEUTICS
(2019)
DOI /
10.3390/pharmaceutics11110597
Gold DOAJ, Green published
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1
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Non-viral mediated gene therapy in human cystic fibrosis airway epithelial cells recovers chloride channel functionality
Sainz-Ramos, Myriam; Villate-Beitia, Ilia; Gallego, Idoia; Qtaish, Nuseibah A. L.; Lopez-Mendez, Tania B.; Eritja, Ramon; Grijalvo, Santiago; Puras, Gustavo; Luis Pedraz, Jose
INTERNATIONAL JOURNAL OF PHARMACEUTICS
0378-5173 (2020)
DOI /
10.1016/j.ijpharm.2020.119757
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0
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Hybrid Alginate Protein-Coated Graphene Oxide Microcapsules Enhance the Functionality of Erythropoietin Secreting C2C12 Myoblasts
Saenz del Burgo, Laura; Ciriza, Jesus; Acarregui, Argia; Gurruchaga, Haritz; Javier Blanco, Francisco; Orive, Gorka; Maria Hernandez, Rosa; Luis Pedraz, Jose
MOLECULAR PHARMACEUTICS
1543-8384 (2017)
DOI /
10.1021/acs.molpharmaceut.6b01078
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1
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The role of osmolarity adjusting agents in the regulation of encapsulated cell behavior to provide a safer and more predictable delivery of therapeutics
Gonzalez-Pujana, Ainhoa; Rementeria, Aitor; Javier Blanco, Francisco; Igartua, Manoli; Luis Pedraz, Jose; Santos-Vizcaino, Edorta; Maria Hernandez, Rosa
DRUG DELIVERY
1071-7544 (2017)
DOI /
10.1080/10717544.2017.1391894
Gold DOAJ, Green published
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3
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Review
Advances in the slow freezing cryopreservation of microencapsulated cells
Gurruchaga, H.; Saenz del Burgo, L.; Hernandez, R. M.; Orive, G.; Selden, C.; Fuller, B.; Ciriza, J.; Pedraz, J. L.
JOURNAL OF CONTROLLED RELEASE
0168-3659 (2018)
DOI /
10.1016/j.jconrel.2018.05.016
Green published
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2
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Enzymatic crosslinked gelatin 3D scaffolds for bone tissue engineering
Carmen Echave, Mari; Pimenta-Lopes, Carolina; Pedraz, Jose Luis; Mehrali, Mehdi; Dolatshahi-Pirouz, Alireza; Ventura, Fransesc; Orive, Gorka
INTERNATIONAL JOURNAL OF PHARMACEUTICS
0378-5173 (2019)
DOI /
10.1016/j.ijpharm.2019.02.043
Green submitted
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1
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Encapsulation of Oleuropein in Nanostructured Lipid Carriers: Biocompatibility and Antioxidant Efficacy in Lung Epithelial Cells
Huguet-Casquero, Amaia; Moreno-Sastre, Maria; Belen Lopez-Mendez, Tania; Gainza, Eusebio; Luis Pedraz, Jose
PHARMACEUTICS
(2020)
DOI /
10.3390/pharmaceutics12050429
Green published, Gold
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1
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Clay Minerals as Bioink Ingredients for 3D Printing and 3D Bioprinting: Application in Tissue Engineering and Regenerative Medicine
Garcia-Villen, Fatima; Ruiz-Alonso, Sandra; Lafuente-Merchan, Markel; Gallego, Idoia; Sainz-Ramos, Myriam; Saenz-del-Burgo, Laura; Pedraz, Jose Luis
PHARMACEUTICS
(2021)
DOI /
10.3390/pharmaceutics13111806
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1
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Extraction of the antioxidant phytocomplex from wine-making by-products and sustainable loading in phospholipid vesicles specifically tailored for skin protection
Perra, Matteo; Lozano-Sanchez, Jesus; Leyva-Jimenez, Francisco-Javier; Segura-Carretero, Antonio; Pedraz, Jose Luis; Bacchetta, Gianluigi; Muntoni, Aldo; De Gioannis, Giorgia; Manca, Maria Letizia; Manconi, Maria
BIOMEDICINE & PHARMACOTHERAPY
0753-3322 (2021)
DOI /
10.1016/j.biopha.2021.111959
Green published, Gold