Pharmacology & Toxicology


  Listando 37 trabajos del autor/autora 38
Lista de trabajos en el área Pharmacology & Toxicology
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Article Zoanthamine Alkaloids from the Zoantharian Zoanthus cf. pulchellus and Their Effects in Neuroinflammation Guillen, Paul O.; Gegunde, Sandra; Jaramillo, Karla B.; Alfonso, Amparo; Calabro, Kevin; Alonso, Eva; Rodriguez, Jenny; Botana, Luis M.; Thomas, Olivier P. MARINE DRUGS (2018) DOI / 10.3390/md16070242 Gold DOAJ, Green published
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Article Tetracyclic Truncated Analogue of the Marine Toxin Gambierol Modifies NMDA, Tau, and Amyloid beta Expression in Mice Brains: Implications in AD Pathology Alonso, Eva; Vieira, Andres C.; Rodriguez, Ines; Alvarino, Rebeca; Gegunde, Sandra; Fuwa, Haruhiko; Suga, Yuto; Sasaki, Makoto; Alfonso, Amparo; Manuel Cifuentes, Jose; Botana, Luis M. ACS CHEMICAL NEUROSCIENCE 1948-7193 (2017) DOI / 10.1021/acschemneuro.7b00012
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Article Caniferolide A, a Macrolide from Streptomyces caniferus, Attenuates Neuroinflammation, Oxidative Stress, Amyloid-Beta, and Tau Pathology in Vitro Alvarino, Rebeca; Alonso, Eva; Lacret, Rodney; Oves-Costales, Daniel; Genilloud, Olga; Reyes, Fernando; Alfonso, Amparo; Botana, Luis M. MOLECULAR PHARMACEUTICS 1543-8384 (2019) DOI / 10.1021/acs.molpharmaceut.8b01090
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Article Structure Elucidation and Biological Evaluation of Maitotoxin-3, a Homologue of Gambierone, from Gambierdiscus belizeanus Boente-Juncal, Andrea; Alvarez, Mercedes; Antelo, Alvaro; Rodriguez, Ines; Calabro, Kevin; Vale, Carmen; Thomas, Olivier P.; Botana, Luis M. TOXINS (2019) DOI / 10.3390/toxins11020079 Gold DOAJ, Green published
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Review Human Poisoning from Marine Toxins: Unknowns for Optimal Consumer Protection Vilarino, Natalia; Carmen Louzao, M.; Abal, Paula; Cagide, Eva; Carrera, Cristina; Vieytes, Mercedes R.; Botana, Luis M. TOXINS (2018) DOI / 10.3390/toxins10080324 Gold DOAJ, Green published
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Article Streptocyclinones A and B ameliorate Alzheimer's disease pathological processes in vitro Alvarino, Rebeca; Alonso, Eva; Lacret, Rodney; Oves-Costales, Daniel; Genilloud, Olga; Reyes, Fernando; Alfonso, Amparo; Botana, Luis M. NEUROPHARMACOLOGY 0028-3908 (2018) DOI / 10.1016/j.neuropharm.2018.09.008
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Article Gracilin A Derivatives Target Early Events in Alzheimer's Disease: in Vitro Effects on Neuroinflammation and Oxidative Stress Alvarino, Rebeca; Alonso, Eva; Abbasov, Mikail E.; Chaheine, Christian M.; Conner, Michael L.; Romo, Daniel; Alfonso, Amparo; Botana, Luis M. ACS CHEMICAL NEUROSCIENCE 1948-7193 (2019) DOI / 10.1021/acschemneuro.9b00329 Green accepted
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Article Bromotryptamine and Bromotyramine Derivatives from the Tropical Southwestern Pacific Sponge Narrabeena nigra Miguel-Gordo, Maria; Gegunde, Sandra; Calabro, Kevin; Jennings, Laurence K.; Alfonso, Amparo; Genta-Jouve, Gregory; Vacelet, Jean; Botana, Luis M.; Thomas, Olivier P. MARINE DRUGS (2019) DOI / 10.3390/md17060319 Gold DOAJ, Green published
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Article Futunamine, a Pyrrole-Imidazole Alkaloid from the Sponge Stylissa aff. carteri Collected off the Futuna Islands Miguel-Gordo, Maria; Gegunde, Sandra; Jennings, Laurence K.; Genta-Jouve, Gregory; Calabro, Kevin; Alfonso, Amparo; Botana, Luis M.; Thomas, Olivier P. JOURNAL OF NATURAL PRODUCTS 0163-3864 (2020) DOI / 10.1021/acs.jnatprod.0c00223
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Article The association of bacterial C-9-based TTX-like compounds with Prorocentrum minimum opens new uncertainties about shellfish seafood safety Rodriguez, Ines; Alfonso, Amparo; Alonso, Eva; Rubiolo, Juan A.; Roel, Maria; Vlamis, Aristidis; Katikou, Panagiota; Jackson, Stephen A.; Menon, Margassery Lekha; Dobson, Alan; Botana, Luis M. SCIENTIFIC REPORTS 2045-2322 (2017) DOI / 10.1038/srep40880 Gold, Green published
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Article Transcriptomic Analysis of Ciguatoxin-Induced Changes in Gene Expression in Primary Cultures of Mice Cortical Neurons Rubiolo, Juan Andres; Vale, Carmen; Boente-Juncal, Andrea; Hirama, Masahiro; Yamashita, Shuji; Camina, Mercedes; Vieytes, Mercedes R.; Botana, Luis M. TOXINS (2018) DOI / 10.3390/toxins10050192 Gold DOAJ, Green published
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Article Oral Chronic Toxicity of the Safe Tetrodotoxin Dose Proposed by the European Food Safety Authority and Its Additive Effect with Saxitoxin Boente-Juncal, Andrea; Otero, Paz; Rodriguez, Ines; Camina, Mercedes; Rodriguez-Vieytes, Mercedes; Vale, Carmen; Botana, Luis M. TOXINS (2020) DOI / 10.3390/toxins12050312 Gold DOAJ, Green published
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Article Tetrodotoxins Occurrence in Non-Traditional Vectors of the North Atlantic Waters (Portuguese Maritime Territory, and Morocco Coast) Silva, Marisa; Rodriguez, Ines; Barreiro, Aldo; Kaufmann, Manfred; Neto, Ana Isabel; Hassouani, Meryem; Sabour, Brahim; Alfonso, Amparo; Botana, Luis M.; Vasconcelos, Vitor TOXINS (2019) DOI / 10.3390/toxins11060306 Gold DOAJ, Green published
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Article Crambescin C1 Acts as A Possible Substrate of iNOS and eNOS Increasing Nitric Oxide Production and Inducing In Vivo Hypotensive Effect Rubiolo, Juan A.; Lence, Emilio; Gonzalez-Bello, Concepcion; Roel, Maria; Gil-Longo, Jose; Campos-Toimil, Manuel; Ternon, Eva; Thomas, Olivier P.; Gonzalez-Cantalapiedra, Antonio; Lopez-Alonso, Henar; Vieytes, Mercedes R.; Botana, Luis M. FRONTIERS IN PHARMACOLOGY (2021) DOI / 10.3389/fphar.2021.694639 Gold, Green published
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Article Anhydroexfoliamycin, a Streptomyces Secondary Metabolite, Mitigates Microglia-Driven Inflammation Gegunde, Sandra; Alfonso, Amparo; Alvarino, Rebeca; Perez-Fuentes, Nadia; Botana, Luis M. ACS CHEMICAL NEUROSCIENCE 1948-7193 (2021) DOI / 10.1021/acschemneuro.1c00033
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Article Acute Oral Toxicity of Tetrodotoxin in Mice: Determination of Lethal Dose 50 (LD50) and No Observed Adverse Effect Level (NOAEL) Abal, Paula; Louzao, M. Carmen; Antelo, Alvaro; Alvarez, Mercedes; Cagide, Eva; Vilarino, Natalia; Vieytes, Mercedes R.; Botana, Luis M. TOXINS (2017) DOI / 10.3390/toxins9030075 Gold DOAJ, Green published
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Article Reevaluation of the acute toxicity of palytoxin in mice: Determination of lethal dose 50 (LD50) and No-observed-adverse-effect level (NOAEL) Boente-Juncal, Andrea; Vale, Carmen; Camina, Mercedes; Cifuentes, J. Manuel; Vieytes, Mercedes R.; Botana, Luis M. TOXICON 0041-0101 (2020) DOI / 10.1016/j.toxicon.2020.01.010
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Article Single and combined effects of regulated and emerging mycotoxins on viability and mitochondrial function of SH-SY5Y cells Perez-Fuentes, Nadia; Alvarin, Rebeca; Alfonso, Amparo; Gonzalez-Jartin, Jesus; Gegunde, Sandra; Vieytes, Mercedes R.; Botana, Luis M. FOOD AND CHEMICAL TOXICOLOGY 0278-6915 (2021) DOI / 10.1016/j.fct.2021.112308 Hybrid
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Article Targeting Chloride Ion Channels: New Insights into the Mechanism of Action of the Marine Toxin Azaspiracid Boente-Juncal, Andrea; Raposo-Garcia, Sandra; Louzao, M. Carmen; Vale, Carmen; Botana, Luis M. CHEMICAL RESEARCH IN TOXICOLOGY 0893-228X (2021) DOI / 10.1021/acs.chemrestox.0c00494
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Article Tavarua Deoxyriboside A and Jasplakinolide as Potential Neuroprotective Agents: Effects on Cellular Models of Oxidative Stress and Neuroinflammation Alvarino, Rebeca; Alonso, Eva; Tabudravu, Jioji N.; Perez-Fuentes, Nadia; Alfonso, Amparo; Botana, Luis M. ACS CHEMICAL NEUROSCIENCE 1948-7193 (2021) DOI / 10.1021/acschemneuro.0c00626
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Article Chronic In Vivo Effects of Repeated Exposure to Low Oral Doses of Tetrodotoxin: Preliminary Evidence of Nephrotoxicity and Cardiotoxicity Boente-Juncal, Andrea; Vale, Carmen; Cifuentes, Manuel; Otero, Paz; Camina, Mercedes; Rodriguez-Vieytes, Mercedes; Miguel Botana, Luis TOXINS (2019) DOI / 10.3390/toxins11020096 Gold DOAJ, Green published
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Article First report of Fusarium foetens as a mycotoxin producer Gonzalez-Jartin, Jesus M.; Alfonso, Amparo; Sainz, Maria J.; Vieytes, Mercedes R.; Aguin, Olga; Ferreiroa, Vanesa; Botana, Luis M. MYCOTOXIN RESEARCH 0178-7888 (2019) DOI / 10.1007/s12550-019-00341-3
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Article Biological Activities of Cyclic and Acyclic B-Type Laxaphycins in SH-SY5Y Human Neuroblastoma Cells Alvarino, Rebeca; Alonso, Eva; Bornancin, Louis; Bonnard, Isabelle; Inguimbert, Nicolas; Banaigs, Bernard; Botana, Luis M. MARINE DRUGS (2020) DOI / 10.3390/md18070364 Gold DOAJ, Green published
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Article Detection of Cyclic Imine Toxins in Dietary Supplements of Green Lipped Mussels (Perna canaliculus) and in Shellfish Mytilus chilensis Otero, Paz; Vale, Carmen; Boente-Juncal, Andrea; Costas, Celia; Louzao, M. Carmen; Botana, Luis M. TOXINS (2020) DOI / 10.3390/toxins12100613 Gold DOAJ, Green published
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Article Sphaerococcus coronopifolius bromoterpenes as potential cancer stem cell-targeting agents Alves, Celso; Serrano, Eurico; Silva, Joana; Rodrigues, Carlos; Pinteus, Susete; Gaspar, Helena; Botana, Luis M.; Alpoim, Maria C.; Pedrosa, Rui BIOMEDICINE & PHARMACOTHERAPY 0753-3322 (2020) DOI / 10.1016/j.biopha.2020.110275 Gold other
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Article In Vivo Evaluation of the Chronic Oral Toxicity of the Marine Toxin Palytoxin Boente-Juncal, Andrea; Raposo-Garcia, Sandra; Vale, Carmen; Carmen Louzao, M.; Otero, Paz; Botana, Luis M. TOXINS (2020) DOI / 10.3390/toxins12080489 Gold DOAJ, Green published
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Article MONITORING OF FRESHWATER TOXINS IN EUROPEAN ENVIRONMENTAL WATERS BY USING NOVEL MULTI-DETECTION METHODS Rodriguez, Ines; Fraga, Maria; Alfonso, Amparo; Guillebault, Delphine; Medlin, Linda; Baudart, Julia; Jacob, Pauline; Helmi, Karim; Meyer, Thomas; Breitenbach, Ulrich; Holden, Nicholas M.; Boots, Bas; Spurio, Roberto; Cimarelli, Lucia; Mancini, Laura; Marc ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY 0730-7268 (2017) DOI / 10.1002/etc.3577 Green submitted
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Article Characterization of the dinophysistoxin-2 acute oral toxicity in mice to define the Toxicity Equivalency Factor Abal, Paula; Carmen Louzao, M.; Manuel Cifuentes, Jose; Vilarino, Natalia; Rodriguez, Ines; Alfonso, Amparo; Vieytes, Mercedes R.; Botana, Luis M. FOOD AND CHEMICAL TOXICOLOGY 0278-6915 (2017) DOI / 10.1016/j.fct.2017.02.023
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Article Partial Blockade of Human Voltage-Dependent Sodium Channels by the Marine Toxins Azaspiracids Boente-Juncal, Andrea; Raposo-Garcia, Sandra; Costas, Celia; Louzao, M. Carmen; Vale, Carmen; Botana, Luis M. CHEMICAL RESEARCH IN TOXICOLOGY 0893-228X (2020) DOI / 10.1021/acs.chemrestox.0c00216
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Article Quantification of PSP toxins in toxic shellfish matrices using post column oxidation liquid chromatography and pre-column oxidation liquid chromatography methods suggests post-column oxidation liquid chromatography as a good monitoring method of choice Rey, Veroica; Botana, Ana M.; Botana, Luis M. TOXICON 0041-0101 (2017) DOI / 10.1016/j.toxicon.2017.02.003
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Article Structure and biological evaluation of new cyclic and acyclic laxaphycin-A type peptides Bornancin, Louis; Alonso, Eva; Alvarino, Rebeca; Inguimbert, Nicolas; Bonnard, Isabelle; Botana, Luis M.; Banaigs, Bernard BIOORGANIC & MEDICINAL CHEMISTRY 0968-0896 (2019) DOI / 10.1016/j.bmc.2019.03.046
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Article DSP Toxin Distribution across Organs in Mice after Acute Oral Administration Louzao, M. Carmen; Abal, Paula; Costas, Celia; Suzuki, Toshiyuki; Watanabe, Ryuichi; Vilarino, Natalia; Botana, Ana M.; R. Vieytes, Mercedes; Botana, Luis M. MARINE DRUGS (2021) DOI / 10.3390/md19010023 Gold DOAJ, Green published, Green accepted
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Article Paralytic Shellfish Toxins Occurrence in Non-Traditional Invertebrate Vectors from North Atlantic Waters (Azores, Madeira, and Morocco) Silva, Marisa; Rey, Veronica; Barreiro, Aldo; Kaufmann, Manfred; Neto, Ana Isabel; Hassouani, Meryem; Sabour, Brahim; Botana, Ana; Botana, Luis M.; Vasconcelos, Vitor TOXINS (2018) DOI / 10.3390/toxins10090362 Gold DOAJ, Green published
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Article Acute Toxicity Assessment: Macroscopic and Ultrastructural Effects in Mice Treated with Oral Tetrodotoxin Abal, Paula; Louzao, M. Carmen; Vilarino, Natalia; Vieytes, Mercedes R.; Botana, Luis M. TOXINS (2019) DOI / 10.3390/toxins11060305 Gold DOAJ, Green published
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Review From Marine Origin to Therapeutics: The Antitumor Potential of Marine Algae-Derived Compounds Alves, Celso; Silva, Joana; Pinteus, Susete; Gaspar, Helena; Alpoim, Maria C.; Botana, Luis M.; Pedrosa, Rui FRONTIERS IN PHARMACOLOGY (2018) DOI / 10.3389/fphar.2018.00777 Green published, Gold
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Article Synergistic Effect of Transient Receptor Potential Antagonist and Amiloride against Maitotoxin Induced Calcium Increase and Cytotoxicity in Human Neuronal Stem Cells Boente-Juncal, Andrea; Vale, Carmen; Alfonso, Amparo; Botana, Luis M. ACS CHEMICAL NEUROSCIENCE 1948-7193 (2018) DOI / 10.1021/acschemneuro.8b00128
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Article LC-MS/MS Analysis of the Emerging Toxin Pinnatoxin-G and High Levels of Esterified OA Group Toxins in Galician Commercial Mussels Otero, Paz; Miguens, Natalia; Rodriguez, Ines; Botana, Luis M. TOXINS (2019) DOI / 10.3390/toxins11070394 Green published, Gold, Green submitted

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