Pharmacology & Toxicology
Listando 37 trabajos del autor/autora 38
Lista de trabajos en el área Pharmacology & Toxicology
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Zoanthamine Alkaloids from the Zoantharian Zoanthus cf. pulchellus and Their Effects in Neuroinflammation
Guillen, Paul O.; Gegunde, Sandra; Jaramillo, Karla B.; Alfonso, Amparo; Calabro, Kevin; Alonso, Eva; Rodriguez, Jenny; Botana, Luis M.; Thomas, Olivier P.
MARINE DRUGS
(2018)
DOI /
10.3390/md16070242
Gold DOAJ, Green published
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2
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1
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1
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0
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Article
Tetracyclic Truncated Analogue of the Marine Toxin Gambierol Modifies NMDA, Tau, and Amyloid beta Expression in Mice Brains: Implications in AD Pathology
Alonso, Eva; Vieira, Andres C.; Rodriguez, Ines; Alvarino, Rebeca; Gegunde, Sandra; Fuwa, Haruhiko; Suga, Yuto; Sasaki, Makoto; Alfonso, Amparo; Manuel Cifuentes, Jose; Botana, Luis M.
ACS CHEMICAL NEUROSCIENCE
1948-7193 (2017)
DOI /
10.1021/acschemneuro.7b00012
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13
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1
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Caniferolide A, a Macrolide from Streptomyces caniferus, Attenuates Neuroinflammation, Oxidative Stress, Amyloid-Beta, and Tau Pathology in Vitro
Alvarino, Rebeca; Alonso, Eva; Lacret, Rodney; Oves-Costales, Daniel; Genilloud, Olga; Reyes, Fernando; Alfonso, Amparo; Botana, Luis M.
MOLECULAR PHARMACEUTICS
1543-8384 (2019)
DOI /
10.1021/acs.molpharmaceut.8b01090
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14
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2
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Structure Elucidation and Biological Evaluation of Maitotoxin-3, a Homologue of Gambierone, from Gambierdiscus belizeanus
Boente-Juncal, Andrea; Alvarez, Mercedes; Antelo, Alvaro; Rodriguez, Ines; Calabro, Kevin; Vale, Carmen; Thomas, Olivier P.; Botana, Luis M.
TOXINS
(2019)
DOI /
10.3390/toxins11020079
Gold DOAJ, Green published
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6
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0
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3
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Review
Human Poisoning from Marine Toxins: Unknowns for Optimal Consumer Protection
Vilarino, Natalia; Carmen Louzao, M.; Abal, Paula; Cagide, Eva; Carrera, Cristina; Vieytes, Mercedes R.; Botana, Luis M.
TOXINS
(2018)
DOI /
10.3390/toxins10080324
Gold DOAJ, Green published
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2
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1
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Streptocyclinones A and B ameliorate Alzheimer's disease pathological processes in vitro
Alvarino, Rebeca; Alonso, Eva; Lacret, Rodney; Oves-Costales, Daniel; Genilloud, Olga; Reyes, Fernando; Alfonso, Amparo; Botana, Luis M.
NEUROPHARMACOLOGY
0028-3908 (2018)
DOI /
10.1016/j.neuropharm.2018.09.008
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1
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Gracilin A Derivatives Target Early Events in Alzheimer's Disease: in Vitro Effects on Neuroinflammation and Oxidative Stress
Alvarino, Rebeca; Alonso, Eva; Abbasov, Mikail E.; Chaheine, Christian M.; Conner, Michael L.; Romo, Daniel; Alfonso, Amparo; Botana, Luis M.
ACS CHEMICAL NEUROSCIENCE
1948-7193 (2019)
DOI /
10.1021/acschemneuro.9b00329
Green accepted
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13
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Bromotryptamine and Bromotyramine Derivatives from the Tropical Southwestern Pacific Sponge Narrabeena nigra
Miguel-Gordo, Maria; Gegunde, Sandra; Calabro, Kevin; Jennings, Laurence K.; Alfonso, Amparo; Genta-Jouve, Gregory; Vacelet, Jean; Botana, Luis M.; Thomas, Olivier P.
MARINE DRUGS
(2019)
DOI /
10.3390/md17060319
Gold DOAJ, Green published
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15
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Futunamine, a Pyrrole-Imidazole Alkaloid from the Sponge Stylissa aff. carteri Collected off the Futuna Islands
Miguel-Gordo, Maria; Gegunde, Sandra; Jennings, Laurence K.; Genta-Jouve, Gregory; Calabro, Kevin; Alfonso, Amparo; Botana, Luis M.; Thomas, Olivier P.
JOURNAL OF NATURAL PRODUCTS
0163-3864 (2020)
DOI /
10.1021/acs.jnatprod.0c00223
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10
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The association of bacterial C-9-based TTX-like compounds with Prorocentrum minimum opens new uncertainties about shellfish seafood safety
Rodriguez, Ines; Alfonso, Amparo; Alonso, Eva; Rubiolo, Juan A.; Roel, Maria; Vlamis, Aristidis; Katikou, Panagiota; Jackson, Stephen A.; Menon, Margassery Lekha; Dobson, Alan; Botana, Luis M.
SCIENTIFIC REPORTS
2045-2322 (2017)
DOI /
10.1038/srep40880
Gold, Green published
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0
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2
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Article
Transcriptomic Analysis of Ciguatoxin-Induced Changes in Gene Expression in Primary Cultures of Mice Cortical Neurons
Rubiolo, Juan Andres; Vale, Carmen; Boente-Juncal, Andrea; Hirama, Masahiro; Yamashita, Shuji; Camina, Mercedes; Vieytes, Mercedes R.; Botana, Luis M.
TOXINS
(2018)
DOI /
10.3390/toxins10050192
Gold DOAJ, Green published
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10
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Article
Oral Chronic Toxicity of the Safe Tetrodotoxin Dose Proposed by the European Food Safety Authority and Its Additive Effect with Saxitoxin
Boente-Juncal, Andrea; Otero, Paz; Rodriguez, Ines; Camina, Mercedes; Rodriguez-Vieytes, Mercedes; Vale, Carmen; Botana, Luis M.
TOXINS
(2020)
DOI /
10.3390/toxins12050312
Gold DOAJ, Green published
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8
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Tetrodotoxins Occurrence in Non-Traditional Vectors of the North Atlantic Waters (Portuguese Maritime Territory, and Morocco Coast)
Silva, Marisa; Rodriguez, Ines; Barreiro, Aldo; Kaufmann, Manfred; Neto, Ana Isabel; Hassouani, Meryem; Sabour, Brahim; Alfonso, Amparo; Botana, Luis M.; Vasconcelos, Vitor
TOXINS
(2019)
DOI /
10.3390/toxins11060306
Gold DOAJ, Green published
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13
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Crambescin C1 Acts as A Possible Substrate of iNOS and eNOS Increasing Nitric Oxide Production and Inducing In Vivo Hypotensive Effect
Rubiolo, Juan A.; Lence, Emilio; Gonzalez-Bello, Concepcion; Roel, Maria; Gil-Longo, Jose; Campos-Toimil, Manuel; Ternon, Eva; Thomas, Olivier P.; Gonzalez-Cantalapiedra, Antonio; Lopez-Alonso, Henar; Vieytes, Mercedes R.; Botana, Luis M.
FRONTIERS IN PHARMACOLOGY
(2021)
DOI /
10.3389/fphar.2021.694639
Gold, Green published
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7
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Article
Anhydroexfoliamycin, a Streptomyces Secondary Metabolite, Mitigates Microglia-Driven Inflammation
Gegunde, Sandra; Alfonso, Amparo; Alvarino, Rebeca; Perez-Fuentes, Nadia; Botana, Luis M.
ACS CHEMICAL NEUROSCIENCE
1948-7193 (2021)
DOI /
10.1021/acschemneuro.1c00033
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2
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1
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Acute Oral Toxicity of Tetrodotoxin in Mice: Determination of Lethal Dose 50 (LD50) and No Observed Adverse Effect Level (NOAEL)
Abal, Paula; Louzao, M. Carmen; Antelo, Alvaro; Alvarez, Mercedes; Cagide, Eva; Vilarino, Natalia; Vieytes, Mercedes R.; Botana, Luis M.
TOXINS
(2017)
DOI /
10.3390/toxins9030075
Gold DOAJ, Green published
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6
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0
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Article
Reevaluation of the acute toxicity of palytoxin in mice: Determination of lethal dose 50 (LD50) and No-observed-adverse-effect level (NOAEL)
Boente-Juncal, Andrea; Vale, Carmen; Camina, Mercedes; Cifuentes, J. Manuel; Vieytes, Mercedes R.; Botana, Luis M.
TOXICON
0041-0101 (2020)
DOI /
10.1016/j.toxicon.2020.01.010
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9
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Single and combined effects of regulated and emerging mycotoxins on viability and mitochondrial function of SH-SY5Y cells
Perez-Fuentes, Nadia; Alvarin, Rebeca; Alfonso, Amparo; Gonzalez-Jartin, Jesus; Gegunde, Sandra; Vieytes, Mercedes R.; Botana, Luis M.
FOOD AND CHEMICAL TOXICOLOGY
0278-6915 (2021)
DOI /
10.1016/j.fct.2021.112308
Hybrid
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10
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Targeting Chloride Ion Channels: New Insights into the Mechanism of Action of the Marine Toxin Azaspiracid
Boente-Juncal, Andrea; Raposo-Garcia, Sandra; Louzao, M. Carmen; Vale, Carmen; Botana, Luis M.
CHEMICAL RESEARCH IN TOXICOLOGY
0893-228X (2021)
DOI /
10.1021/acs.chemrestox.0c00494
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4
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Tavarua Deoxyriboside A and Jasplakinolide as Potential Neuroprotective Agents: Effects on Cellular Models of Oxidative Stress and Neuroinflammation
Alvarino, Rebeca; Alonso, Eva; Tabudravu, Jioji N.; Perez-Fuentes, Nadia; Alfonso, Amparo; Botana, Luis M.
ACS CHEMICAL NEUROSCIENCE
1948-7193 (2021)
DOI /
10.1021/acschemneuro.0c00626
Mentions
5
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Chronic In Vivo Effects of Repeated Exposure to Low Oral Doses of Tetrodotoxin: Preliminary Evidence of Nephrotoxicity and Cardiotoxicity
Boente-Juncal, Andrea; Vale, Carmen; Cifuentes, Manuel; Otero, Paz; Camina, Mercedes; Rodriguez-Vieytes, Mercedes; Miguel Botana, Luis
TOXINS
(2019)
DOI /
10.3390/toxins11020096
Gold DOAJ, Green published
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3
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0
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Article
First report of Fusarium foetens as a mycotoxin producer
Gonzalez-Jartin, Jesus M.; Alfonso, Amparo; Sainz, Maria J.; Vieytes, Mercedes R.; Aguin, Olga; Ferreiroa, Vanesa; Botana, Luis M.
MYCOTOXIN RESEARCH
0178-7888 (2019)
DOI /
10.1007/s12550-019-00341-3
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5
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Biological Activities of Cyclic and Acyclic B-Type Laxaphycins in SH-SY5Y Human Neuroblastoma Cells
Alvarino, Rebeca; Alonso, Eva; Bornancin, Louis; Bonnard, Isabelle; Inguimbert, Nicolas; Banaigs, Bernard; Botana, Luis M.
MARINE DRUGS
(2020)
DOI /
10.3390/md18070364
Gold DOAJ, Green published
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2
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0
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Article
Detection of Cyclic Imine Toxins in Dietary Supplements of Green Lipped Mussels (Perna canaliculus) and in Shellfish Mytilus chilensis
Otero, Paz; Vale, Carmen; Boente-Juncal, Andrea; Costas, Celia; Louzao, M. Carmen; Botana, Luis M.
TOXINS
(2020)
DOI /
10.3390/toxins12100613
Gold DOAJ, Green published
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3
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Sphaerococcus coronopifolius bromoterpenes as potential cancer stem cell-targeting agents
Alves, Celso; Serrano, Eurico; Silva, Joana; Rodrigues, Carlos; Pinteus, Susete; Gaspar, Helena; Botana, Luis M.; Alpoim, Maria C.; Pedrosa, Rui
BIOMEDICINE & PHARMACOTHERAPY
0753-3322 (2020)
DOI /
10.1016/j.biopha.2020.110275
Gold other
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2
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In Vivo Evaluation of the Chronic Oral Toxicity of the Marine Toxin Palytoxin
Boente-Juncal, Andrea; Raposo-Garcia, Sandra; Vale, Carmen; Carmen Louzao, M.; Otero, Paz; Botana, Luis M.
TOXINS
(2020)
DOI /
10.3390/toxins12080489
Gold DOAJ, Green published
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2
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MONITORING OF FRESHWATER TOXINS IN EUROPEAN ENVIRONMENTAL WATERS BY USING NOVEL MULTI-DETECTION METHODS
Rodriguez, Ines; Fraga, Maria; Alfonso, Amparo; Guillebault, Delphine; Medlin, Linda; Baudart, Julia; Jacob, Pauline; Helmi, Karim; Meyer, Thomas; Breitenbach, Ulrich; Holden, Nicholas M.; Boots, Bas; Spurio, Roberto; Cimarelli, Lucia; Mancini, Laura; Marc
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
0730-7268 (2017)
DOI /
10.1002/etc.3577
Green submitted
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2
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Characterization of the dinophysistoxin-2 acute oral toxicity in mice to define the Toxicity Equivalency Factor
Abal, Paula; Carmen Louzao, M.; Manuel Cifuentes, Jose; Vilarino, Natalia; Rodriguez, Ines; Alfonso, Amparo; Vieytes, Mercedes R.; Botana, Luis M.
FOOD AND CHEMICAL TOXICOLOGY
0278-6915 (2017)
DOI /
10.1016/j.fct.2017.02.023
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1
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Partial Blockade of Human Voltage-Dependent Sodium Channels by the Marine Toxins Azaspiracids
Boente-Juncal, Andrea; Raposo-Garcia, Sandra; Costas, Celia; Louzao, M. Carmen; Vale, Carmen; Botana, Luis M.
CHEMICAL RESEARCH IN TOXICOLOGY
0893-228X (2020)
DOI /
10.1021/acs.chemrestox.0c00216
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1
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Quantification of PSP toxins in toxic shellfish matrices using post column oxidation liquid chromatography and pre-column oxidation liquid chromatography methods suggests post-column oxidation liquid chromatography as a good monitoring method of choice
Rey, Veroica; Botana, Ana M.; Botana, Luis M.
TOXICON
0041-0101 (2017)
DOI /
10.1016/j.toxicon.2017.02.003
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2
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Structure and biological evaluation of new cyclic and acyclic laxaphycin-A type peptides
Bornancin, Louis; Alonso, Eva; Alvarino, Rebeca; Inguimbert, Nicolas; Bonnard, Isabelle; Botana, Luis M.; Banaigs, Bernard
BIOORGANIC & MEDICINAL CHEMISTRY
0968-0896 (2019)
DOI /
10.1016/j.bmc.2019.03.046
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2
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DSP Toxin Distribution across Organs in Mice after Acute Oral Administration
Louzao, M. Carmen; Abal, Paula; Costas, Celia; Suzuki, Toshiyuki; Watanabe, Ryuichi; Vilarino, Natalia; Botana, Ana M.; R. Vieytes, Mercedes; Botana, Luis M.
MARINE DRUGS
(2021)
DOI /
10.3390/md19010023
Gold DOAJ, Green published, Green accepted
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1
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Paralytic Shellfish Toxins Occurrence in Non-Traditional Invertebrate Vectors from North Atlantic Waters (Azores, Madeira, and Morocco)
Silva, Marisa; Rey, Veronica; Barreiro, Aldo; Kaufmann, Manfred; Neto, Ana Isabel; Hassouani, Meryem; Sabour, Brahim; Botana, Ana; Botana, Luis M.; Vasconcelos, Vitor
TOXINS
(2018)
DOI /
10.3390/toxins10090362
Gold DOAJ, Green published
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2
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Acute Toxicity Assessment: Macroscopic and Ultrastructural Effects in Mice Treated with Oral Tetrodotoxin
Abal, Paula; Louzao, M. Carmen; Vilarino, Natalia; Vieytes, Mercedes R.; Botana, Luis M.
TOXINS
(2019)
DOI /
10.3390/toxins11060305
Gold DOAJ, Green published
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1
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Review
From Marine Origin to Therapeutics: The Antitumor Potential of Marine Algae-Derived Compounds
Alves, Celso; Silva, Joana; Pinteus, Susete; Gaspar, Helena; Alpoim, Maria C.; Botana, Luis M.; Pedrosa, Rui
FRONTIERS IN PHARMACOLOGY
(2018)
DOI /
10.3389/fphar.2018.00777
Green published, Gold
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1
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Article
Synergistic Effect of Transient Receptor Potential Antagonist and Amiloride against Maitotoxin Induced Calcium Increase and Cytotoxicity in Human Neuronal Stem Cells
Boente-Juncal, Andrea; Vale, Carmen; Alfonso, Amparo; Botana, Luis M.
ACS CHEMICAL NEUROSCIENCE
1948-7193 (2018)
DOI /
10.1021/acschemneuro.8b00128
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2
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LC-MS/MS Analysis of the Emerging Toxin Pinnatoxin-G and High Levels of Esterified OA Group Toxins in Galician Commercial Mussels
Otero, Paz; Miguens, Natalia; Rodriguez, Ines; Botana, Luis M.
TOXINS
(2019)
DOI /
10.3390/toxins11070394
Green published, Gold, Green submitted