Pharmacology & Toxicology
Listando 21 trabajos del autor/autora 38
Lista de trabajos en el área Pharmacology & Toxicology
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Article
Host-Directed FDA-Approved Drugs with Antiviral Activity against SARS-CoV-2 Identified by Hierarchical In Silico/In Vitro Screening Methods
Ginex, Tiziana; Garaigorta, Urtzi; Ramirez, David; Castro, Victoria; Nozal, Vanesa; Maestro, Ines; Garcia-Carceles, Javier; Campillo, Nuria E.; Martinez, ANA; Gastaminza, Pablo; Gil, Carmen
PHARMACEUTICALS
(2021)
DOI /
10.3390/ph14040332
Green submitted, Gold, Green published
Mentions
41
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Article
COVID-19: Drug Targets and Potential Treatments
Gil, Carmen; Ginex, Tiziana; Maestro, Ines; Nozal, Vanesa; Barrado-Gil, Lucia; Angel Cuesta-Geijo, Miguel; Urquiza, Jesus; Ramirez, David; Alonso, Covadonga; Campillo, Nuria E.; Martinez, ANA
JOURNAL OF MEDICINAL CHEMISTRY
0022-2623 (2020)
DOI /
10.1021/acs.jmedchem.0c00606
Green published, Green submitted, Bronze
Mentions
20
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1
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Benzothiazole-Based LRRK2 Inhibitors as Wnt Enhancers and Promoters of Oligodendrocytic Fate
Zaldivar-Diez, Josefa; Li, Lingling; Garcia, Ana M.; Zhao, Wen-Ning; Medina-Menendez, Cristina; Haggarty, Stephen J.; Gil, Carmen; Morales, Aixa, V; Martinez, ANA
JOURNAL OF MEDICINAL CHEMISTRY
0022-2623 (2020)
DOI /
10.1021/acs.jmedchem.9b01752
Green submitted
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3
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1
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Review
Protein kinase inhibitors for amyotrophic lateral sclerosis therapy
Palomo, Valle; Nozal, Vanesa; Rojas-Prats, Elisa; Gil, Carmen; Martinez, ANA
BRITISH JOURNAL OF PHARMACOLOGY
0007-1188 (2020)
DOI /
10.1111/bph.15221
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1
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1
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Targeting nuclear protein TDP-43 by cell division cycle kinase 7 inhibitors: A new therapeutic approach for amyotrophic lateral
Rojas-Prats, Elisa; Martinez-Gonzalez, Loreto; Gonzalo-Consuegra, Claudia; Liachko, Nicole F.; Perez, Concepcion; Ramirez, David; Kraemer, Brian C.; Martin-Requero, Angeles; Perez, Daniel, I; Gil, Carmen; de Lago, Eva; Martinez, ANA
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
0223-5234 (2021)
DOI /
10.1016/j.ejmech.2020.112968
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10
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Identification of Niemann-Pick C1 protein as a potential novel SARS-CoV-2 intracellular target
Garcia-Dorival, Isabel; Angel Cuesta-Geijo, Miguel; Barrado-Gil, Lucia; Galindo, Inmaculada; Garaigorta, Urtzi; Urquiza, Jesus; del Puerto, Ana; Campillo, Nuria E.; Martinez, ANA; Gastaminza, Pablo; Gil, Carmen; Alonso, Covadonga
ANTIVIRAL RESEARCH
0166-3542 (2021)
DOI /
10.1016/j.antiviral.2021.105167
Green published, Hybrid
Mentions
3
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Review
Drugs in clinical development for the treatment of amyotrophic lateral sclerosis
Martinez, ANA; Palomo Ruiz, Maria del Valle; Perez, Daniel I.; Gil, Carmen
EXPERT OPINION ON INVESTIGATIONAL DRUGS
1354-3784 (2017)
DOI /
10.1080/13543784.2017.1302426
Green submitted
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0
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Enzymatic and solid-phase synthesis of new donepezil-based L-and D-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer ' s disease and cerebral ischemia
Monjas, Leticia; Arce, Mariana P.; Leon, Rafael; Egea, Javier; Perez, Concepcion; Villarroya, Mercedes; Lopez, Manuela G.; Gil, Carmen; Conde, Santiago; Isabel Rodriguez-Franco, Maria
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
0223-5234 (2017)
DOI /
10.1016/j.ejmech.2017.02.034
Green submitted
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Deciphering the enzymatic target of a new family of antischistosomal agents bearing a quinazoline scaffold using complementary computational tools
Sebastian-Perez, Victor; Garcia-Rubia, Alfonso; el-Din, Sayed H. Seif; Sabra, Abdel-Nasser A.; El-Lakkany, Naglaa M.; William, Samia; Blundell, Tom L.; Maes, Louis; Martinez, ANA; Campillo, Nuria E.; Botros, Sanaa S.; Gil, Carmen
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
1475-6366 (2020)
DOI /
10.1080/14756366.2020.1712595
Gold DOAJ, Green published
Mentions
5
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Deciphering the Inhibition of the Neuronal Calcium Sensor 1 and the Guanine Exchange Factor Ric8a with a Small Phenothiazine Molecule for the Rational Generation of Therapeutic Synapse Function Regulators
Roca, Carlos; Martinez-Gonzalez, Loreto; Daniel-Mozo, Miguel; Sastre, Javier; Infantes, Lourdes; Mansilla, Alicia; Chaves-Sanjuan, Antonio; Maria Gonzalez-Rubio, Juana; Gil, Carmen; Javier Canada, H. F.; Martinez, ANA; Jose Sanchez-Barrena, Maria; Campillo
JOURNAL OF MEDICINAL CHEMISTRY
0022-2623 (2018)
DOI /
10.1021/acs.jmedchem.8b00088
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0
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1
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Potential pharmacological strategies targeting the Niemann-Pick C1 receptor and Ebola virus glycoprotein interaction
Morales-Tenorio, Marcos; Ginex, Tiziana; Cuesta-Geijo, Miguel Angel; Campillo, Nuria E.; Munoz-Fontela, Cesar; Alonso, Covadonga; Delgado, Rafael; Gil, Carmen
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
0223-5234 (2021)
DOI /
10.1016/j.ejmech.2021.113654
Green published, Hybrid
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7
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Imidazole Derivatives as Promising Agents for the Treatment of Chagas Disease
de Araujo, Juliann Siciliano; Garcia-Rubia, Alfonso; Sebastian-Perez, Victor; Kalejaiye, Titilola D.; da Silva, Patricia Bernardino; Rosa Fonseca-Berzal, Cristina; Maes, Louis; de Koning, Harry P.; Correia Soeiro, Maria de Nazare; Gil, Carmen
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
0066-4804 (2019)
DOI /
10.1128/aac.02156-18
Green published, Green accepted, Bronze
Mentions
4
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Discovery of Amoebicidal Compounds by Combining Computational and Experimental Approaches
Sebastian-Perez, Victor; Sifaoui, Ines; Reyes-Batlle, Maria; Dominguez-De Barros, Angelica; Lopez-Arencibia, Atteneri; Campillo, Nuria E.; Pinero, Jose E.; Lorenzo-Morales, Jacob; Gil, Carmen
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
0066-4804 (2021)
DOI /
10.1128/aac.01749-20
Mentions
4
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Antiviral drugs targeting endosomal membrane proteins inhibit distant animal and human pathogenic viruses
Galindo, I; Garaigorta, U.; Lasala, F.; Cuesta-Geijo, M. A.; Bueno, P.; Gil, C.; Delgado, R.; Gastaminza, P.; Alonso, C.
ANTIVIRAL RESEARCH
0166-3542 (2021)
DOI /
10.1016/j.antiviral.2020.104990
Green published, Gold other
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1
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The GSK-3-inhibitor VP2.51 produces antidepressant effects associated with adult hippocampal neurogenesis
Perez-Domper, Paloma; Palomo, Valle; Gradari, Simona; Gil, Carmen; de Ceballos, Maria L.; Martinez, ANA; Luis Trejo, Jose
NEUROPHARMACOLOGY
0028-3908 (2017)
DOI /
10.1016/j.neuropharm.2016.12.019
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2
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Identification of potential inhibitors of protein-protein interaction useful to fight against Ebola and other highly pathogenic viruses
Lasala, Fatima; Garcia-Rubia, Alfonso; Requena, Carlos; Galindo, Inmaculada; Cuesta-Geijo, Miguel Angel; Garcia-Dorival, Isabel; Bueno, Paula; Labiod, Nuria; Luczkowiak, Joanna; Martinez, ANA; Campillo, Nuria E.; Alonso, Covadonga; Delgado, Rafael; Gil, Ca
ANTIVIRAL RESEARCH
0166-3542 (2021)
DOI /
10.1016/j.antiviral.2021.105011
Green published
Mentions
3
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Article
Subtly Modulating Glycogen Synthase Kinase 3 beta: Allosteric Inhibitor Development and Their Potential for the Treatment of Chronic Diseases
Palomo, Valle; Perez, Daniel I.; Roca, Carlos; Anderson, Cara; Rodriguez-Muela, Natalia; Perez, Concepcion; Morales-Garcia, Jose A.; Reyes, Julio A.; Campillo, Nuria E.; Perez-Castillo, Ana M.; Rubin, Lee L.; Timchenko, Lubov; Gil, Carmen; Martinez, ANA
JOURNAL OF MEDICINAL CHEMISTRY
0022-2623 (2017)
DOI /
10.1021/acs.jmedchem.7b00395
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2
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Medicinal and Biological Chemistry (MBC) Library: An Efficient Source of New Hits
Sebastian-Perez, Victor; Roca, Carlos; Awale, Mahendra; Reymond, Jean-Louis; Martinez, ANA; Gil, Carmen; Campillo, Nuria E.
JOURNAL OF CHEMICAL INFORMATION AND MODELING
1549-9596 (2017)
DOI /
10.1021/acs.jcim.7b00401
Green submitted
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1
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Article
Leucine rich repeat kinase 2 (LRRK2) inhibitors based on indolinone scaffold: Potential pro-neurogenic agents
Salado, Irene G.; Zaldivar-Diez, Josefa; Sebastian-Perez, Victor; Li, Lingling; Geiger, Larissa; Gonzalez, Silvia; Campillo, Nuria E.; Gil, Carmen; Morales, Aixa V.; Perez, Daniel I.; Martinez, ANA
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
0223-5234 (2017)
DOI /
10.1016/j.ejmech.2017.06.060
Green accepted
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2
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Article
Pharmacological tools based on imidazole scaffold proved the utility of PDE10A inhibitors for Parkinson's disease
Garcia, Ana M.; Salado, Irene G.; Perez, Daniel I.; Brea, Jose; Morales-Garcia, Jose A.; Gonzalez-Garcia, Alejandro; Cadavid, MariaIsabel; Isabel Loza, Maria; Javier Luque, Francisco; Perez-Castillo, Ana; Martinez, ANA; Gil, Carmen
FUTURE MEDICINAL CHEMISTRY
1756-8919 (2017)
DOI /
10.4155/fmc-2017-0005
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2
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Screening of a PDE-focused library identifies imidazoles with in vitro and in vivo antischistosomal activity
Botros, Sanaa S.; William, Samia; Sabra, Abdel-Nasser A.; El-Lakkany, Naglaa M.; el-Din, Sayed H. Seif; Garcia-Rubia, Alfonso; Sebastian-Perez, Victor; Blaazer, Antoni R.; de Heuvel, Erik; Sijm, Maarten; Zheng, Yang; Salado, Irene G.; Munday, Jane C.; Maes
INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE
2211-3207 (2019)
DOI /
10.1016/j.ijpddr.2019.01.001
Gold DOAJ, Green published, Green accepted
