Pharmacology & Toxicology


  Listando 55 trabajos del autor/autora 38
Lista de trabajos en el área Pharmacology & Toxicology
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Article WCK 5107 (Zidebactam) and WCK 5153 Are Novel Inhibitors of PBP2 Showing Potent "beta-Lactam Enhancer" Activity against Pseudomonas aeruginosa, Including Multidrug-Resistant Metallo-beta-Lactamase-Producing High-Risk Clones Moya, Bartolome; Barcelo, Isabel M.; Bhagwat, Sachin; Patel, Mahesh; Bou, German; Papp-Wallace, Krisztina M.; Bonomo, Robert A.; Oliver, Antonio ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 0066-4804 (2017) DOI / 10.1128/aac.02529-16 Green published, Bronze
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Article Recommendations for antibiotic selection for severe nosocomial infections Mensa, Josep; Barberan, Jose; Ferrer, Ricard; Borges, Marcio; Rascado, Pedro; Maseda, Emilio; Oliver, Antonio; Marco, Francesc; Adalia, Ramon; Aguilar, Gerardo; Estella, Angel; Leon Lopez, Rafael; Robles Marcos, Manuel S.; Gonzalez de Molina, Fco J.; Serra REVISTA ESPANOLA DE QUIMIOTERAPIA (2021) DOI / 10.37201/req/126.2021
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Article Spanish nationwide survey on Pseudomonas aeruginosa antimicrobial resistance mechanisms and epidemiology del Barrio-Tofino, Ester; Zamorano, Laura; Cortes-Lara, Sara; Lopez-Causape, Carla; Sanchez-Diener, Irina; Cabot, Gabriel; Bou, German; Martinez-Martinez, Luis; Oliver, Antonio; Galan, Fatima; Gracia, Irene; Rodriguez, Manuel Antonio; Martin, Lina; Sanchez JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 0305-7453 (2019) DOI / 10.1093/jac/dkz147
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Article Combination versus monotherapy as definitive treatment for Pseudomonas aeruginosa bacteraemia: a multicentre retrospective observational cohort study Babich, Tanya; Naucler, Pontus; Valik, John Karlsson; Giske, Christian G.; Benito, Natividad; Cardona, Ruben; Rivera, Alba; Pulcini, Celine; Fattah, Manal Abdel; Haquin, Justine; MacGowan, Alasdair; Grier, Sally; Gibbs, Julie; Chazan, Bibiana; Yanovskay, A JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 0305-7453 (2021) DOI / 10.1093/jac/dkab134
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Article Optimization of a Meropenem-Tobramycin Combination Dosage Regimen against Hypermutable and Nonhypermutable Pseudomonas aeruginosa via Mechanism-Based Modeling and the Hollow-Fiber Infection Model Landersdorfer, Cornelia B.; Rees, Vanessa E.; Yadav, Rajbharan; Rogers, Kate E.; Kim, Tae Hwan; Bergen, Phillip J.; Cheah, Soon-Ee; Boyce, John D.; Peleg, Anton Y.; Oliver, Antonio; Shin, Beom Soo; Nation, Roger L.; Bulitta, Jurgen B. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 0066-4804 (2018) DOI / 10.1128/aac.02055-17 Green published, Bronze
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Article Mechanisms leading to in vivo ceftolozane/tazobactam resistance development during the treatment of infections caused by MDR Pseudomonas aeruginosa Fraile-Ribot, Pablo A.; Cabot, Gabriel; Mulet, Xavier; Perianez, Leonor; Martin-Pena, M. Luisa; Juan, Carlos; Perez, Jose L.; Oliver, Antonio JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 0305-7453 (2018) DOI / 10.1093/jac/dkx424 Bronze
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Article Deciphering beta-lactamase-independent p-lactam resistance evolution trajectories in Pseudomonas aeruginosa Cabot, Gabriel; Florit-Mendoza, Llorenc; Sanchez-Diener, Irina; Zamorano, Laura; Oliver, Antonio JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 0305-7453 (2018) DOI / 10.1093/jac/dky364
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Article Development and validation of the INCREMENT-ESBL predictive score for mortality in patients with bloodstream infections due to extendedspectrum- beta-lactamase-producing Enterobacteriaceae Raquel Palacios-Baena, Zaira; Gutierrez-Gutierrez, Belen; de Cueto, Marina; Viale, Pierluigi; Venditti, Mario; Hernandez-Torres, Alicia; Oliver, Antonio; Martinez-Martinez, Luis; Calbo, Esther; Pintado, Vicente; Gasch, Oriol; Almirante, Benito; Antonio Lep JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 0305-7453 (2017) DOI / 10.1093/jac/dkw513 Green published, Bronze
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Article A Standard Numbering Scheme for Class C beta-Lactamases Mack, Andrew R.; Barnes, Melissa D.; Taracila, Magdalena A.; Hujer, Andrea M.; Hujer, Kristine M.; Cabot, Gabriel; Feldgarden, Michael; Haft, Daniel H.; Klimke, William; van den Akker, Focco; Vila, Alejandro J.; Smania, Andrea; Haider, Shozeb; Papp-Wallace ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 0066-4804 (2020) DOI / 10.1128/aac.01841-19 Green published, Green submitted, Bronze
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Article Activity of Imipenem-Relebactam against a Large Collection of Pseudomonas aeruginosa Clinical Isolates and lsogenic beta-Lactam-Resistant Mutants Fraile-Ribot, Pablo A.; Zamorano, Laura; Orellana, Rocio; del Barrio-Tofino, Ester; Sanchez-Diener, Irina; Cortes-Lara, Sara; Lopez-Causape, Carla; Cabot, Gabriel; Bou, German; Martinez-Martinez, Luis; Oliver, Antonio; Galan, Fatima; Gracia, Irene; Antonio ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 0066-4804 (2020) DOI / 10.1128/aac.02165-19 Bronze, Green published
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Article Molecular mechanisms driving the in vivo development of OXA-10-mediated resistance to ceftolozane/tazobactam and ceftazidime/avibactam during treatment of XDR Pseudomonas aeruginosa infections Arca-Suarez, Jorge; Lasarte-Monterrubio, Cristina; Rodino-Janeiro, Bruno-Kotska; Cabot, Gabriel; Carlos Vazquez-Ucha, Juan; Rodriguez-Iglesias, Manuel; Galan-Sanchez, Fatima; Beceiro, Alejandro; Gonzalez-Bello, Concepcion; Oliver, Antonio; Bou, German JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 0305-7453 (2021) DOI / 10.1093/jac/dkaa396
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Article Association between Pseudomonas aeruginosa O-antigen serotypes, resistance profiles and high-risk clones: results from a Spanish nationwide survey del Barrio-Tofino, Ester; Sanchez-Diener, Irina; Zamorano, Laura; Cortes-Lara, Sara; Lopez-Causape, Carla; Cabot, Gabriel; Bou, German; Martinez-Martinez, Luis; Oliver, Antonio; Galan, Fatima; Gracia, Irene; Antonio Rodriguez, Manuel; Martin, Lina; Manuel JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 0305-7453 (2019) DOI / 10.1093/jac/dkz346 Green accepted
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Article In vitro evolution of cefepime/zidebactam (WCK 5222) resistance in Pseudomonas aeruginosa: dynamics, mechanisms, fitness trade-off and impact on in vivo efficacy Barcelo, Isabel; Cabot, Gabriel; Palwe, Snehal; Joshi, Prashant; Takalkar, Swapna; Periasamy, Hariharan; Cortes-Lara, Sara; Zamorano, Laura; Sanchez-Diener, Irina; Moya, Bartolome; Bhagwat, Sachin; Patel, Mahesh; Oliver, Antonio JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 0305-7453 (2021) DOI / 10.1093/jac/dkab213
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Article Distinct epidemiology and resistance mechanisms affecting ceftolozane/tazobactam in Pseudomonas aeruginosa isolates recovered from ICU patients in Spain and Portugal depicted by WGS Hernandez-Garcia, Marta; Garcia-Castillo, Maria; Garcia-Fernandez, Sergio; Melo-Cristino, Jose; Pinto, Margarida F.; Goncalves, Elsa; Alves, Valquiria; Vieira, Ana Raquel; Ramalheira, Elmano; Sancho, Luisa; Diogo, Jose; Ferreira, Rui; Silva, Tania; Chaves, JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 0305-7453 (2021) DOI / 10.1093/jac/dkaa430
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Article Evaluation of Ceftolozane-Tazobactam in Combination with Meropenem against Pseudomonas aeruginosa Sequence Type 175 in a Hollow-Fiber Infection Model Montero, M.; VanScoy, Brian D.; Lopez-Causape, Carla; Conde, Haley; Adams, Jonathan; Segura, Concepcion; Zamorano, Laura; Oliver, Antonio; Horcajada, Juan P.; Ambrose, Paul G. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 0066-4804 (2018) DOI / 10.1128/aac.00026-18 Green published, Bronze
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Article Effective inhibition of PBPs by cefepime and zidebactam in the presence of VIM-1 drives potent bactericidal activity against MBL-expressing Pseudomonas aeruginosa Moya, Bartolome; Bhagwat, Sachin; Cabot, Gabriel; Bou, German; Patel, Mahesh; Oliver, Antonio JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 0305-7453 (2020) DOI / 10.1093/jac/dkaa036
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Article Risk factors for mortality among patients with Pseudomonas aeruginosa bacteraemia: a retrospective multicentre study Babich, Tanya; Naucler, Pontus; Valik, John Karlsson; Giske, Christian G.; Benito, Natividad; Cardona, Ruben; Rivera, Alba; Pulcini, Celine; Fattah, Manal Abdel; Haquin, Justine; MacGowan, Alasdair; Grier, Sally; Chazan, Bibiana; Yanovskay, Anna; Ben Ami, INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS 0924-8579 (2020) DOI / 10.1016/j.ijantimicag.2019.11.004
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Article Potent beta-Lactam Enhancer Activity of Zidebactam and WCK 5153 against Acinetobacter baumannii, Including Carbapenemase-Producing Clinical Isolates Moya, Bartolome; Barcelo, Isabel M.; Bhagwat, Sachin; Patel, Mahesh; Bou, German; Papp-Wallace, Krisztina M.; Bonomo, Robert A.; Oliver, Antonio ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 0066-4804 (2017) DOI / 10.1128/aac.01238-17 Bronze, Green published
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Article Efficacy of Ceftolozane-Tazobactam in Combination with Colistin against Extensively Drug-Resistant Pseudomonas aeruginosa, Including High-Risk Clones, in an In Vitro Pharmacodynamic Model Montero, Maria; Domene Ochoa, Sandra; Lopez-Causape, Carla; VanScoy, Brian; Luque, Sonia; Sorli, Luisa; Campillo, Nuria; Angulo-Brunet, Ariadna; Padilla, Eduardo; Prim, Nuria; Pomar, Virginia; Rivera, Alba; Grau, Santiago; Ambrose, Paul G.; Oliver, Antonio ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 0066-4804 (2020) DOI / 10.1128/aac.02542-19 Green published, Bronze
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Article Colistin plus meropenem combination is synergistic in vitro against extensively drug-resistant Pseudomonas aeruginosa, including high-risk clones Montero, Maria M.; Domene Ochoa, Sandra; Lopez-Causape, Carla; VanScoy, Brian; Luque, Sonia; Sorli, Luisa; Campillo, Nuria; Padilla, Eduardo; Prim, Nuria; Segura, Concepcion; Pomar, Virginia; Rivera, Alba; Grau, Santiago; Ambrose, Paul G.; Oliver, Antonio; JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE 2213-7165 (2019) DOI / 10.1016/j.jgar.2019.04.012
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Article Evolution of the Pseudomonas aeruginosa Aminoglycoside Mutational Resistome In Vitro and in the Cystic Fibrosis Setting Lopez-Causape, Carla; Rubio, Rosa; Cabot, Gabriel; Oliver, Antonio ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 0066-4804 (2018) DOI / 10.1128/aac.02583-17 Green published, Bronze
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Article Meropenem Combined with Ciprofloxacin Combats Hypermutable Pseudomonas aeruginosa from Respiratory Infections of Cystic Fibrosis Patients Rees, Vanessa E.; Yadav, Rajbharan; Rogers, Kate E.; Bulitta, Juergen B.; Wirth, Veronika; Oliver, Antonio; Boyce, John D.; Peleg, Anton Y.; Nation, Roger L.; Landersdorfer, Cornelia B. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 0066-4804 (2018) DOI / 10.1128/aac.01150-18 Green published, Bronze
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Article In Vivo Emergence of Resistance to Novel Cephalosporin-beta-Lactamase Inhibitor Combinations through the Duplication of Amino Acid D149 from OXA-2 beta-Lactamase (OXA-539) in Sequence Type 235 Pseudomonas aeruginosa Fraile-Ribot, Pablo A.; Mulet, Xavier; Cabot, Gabriel; del Barrio-Tofino, Ester; Juan, Carlos; Perez, Jose L.; Oliver, Antonio ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 0066-4804 (2017) DOI / 10.1128/aac.01117-17 Bronze, Green published
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Article Emergence of Resistance to Novel Cephalosporin-beta-Lactamase Inhibitor Combinations through the Modification of the Pseudomonas aeruginosa MexCD-OprJ Efflux Pump Gomis-Font, Maria A.; Pitart, Cristina; del Barrio-Tofino, Ester; Zboromyrska, Yuliya; Cortes-Lara, Sara; Mulet, Xavier; Marco, Francesc; Vila, Jordi; Lopez-Causape, Carla; Oliver, Antonio ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 0066-4804 (2021) DOI / 10.1128/aac.00089-21
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Article Pseudomonas aeruginosa & nbsp;Susceptibility in Spain: Antimicrobial Activity and Resistance Suppression Evaluation by PK/PD Analysis Valero, Ana; Rodriguez-Gascon, Alicia; Isla, Arantxa; Barrasa, Helena; del Barrio-Tofino, Ester; Oliver, Antonio; Canut, Andres; Solinis, Maria Angeles PHARMACEUTICS (2021) DOI / 10.3390/pharmaceutics13111899 Green published, Gold
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Article Interplay among Resistance Profiles, High-Risk Clones, and Virulence in the Caenorhabditis elegans Pseudomonas aeruginosa Infection Model Sanchez-Diener, Irina; Zamorano, Laura; Lopez-Causape, Carla; Cabot, Gabriel; Mulet, Xavier; Pena, Carmen; del Campo, Rosa; Canton, Rafael; Domenech-Sanchez, Antonio; Martinez-Martinez, Luis; Arcos, Susana C.; Navas, Alfonso; Oliver, Antonio ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 0066-4804 (2017) DOI / 10.1128/aac.01586-17 Green published, Bronze
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Article Use of Calgary and Microfluidic BioFlux Systems To Test the Activity of Fosfomycin and Tobramycin Alone and in Combination against Cystic Fibrosis Pseudomonas aeruginosa Biofilms Diez-Aguilar, Maria; Isabel Morosini, Maria; Koksal, Emin; Oliver, Antonio; Ekkelenkamp, Miquel; Canton, Rafael ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 0066-4804 (2018) DOI / 10.1128/aac.01650-17 Green published, Bronze
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Article Genomics and Susceptibility Profiles of Extensively Drug-Resistant Pseudomonas aeruginosa Isolates from Spain del Barrio-Tofino, Ester; Lopez-Causape, Carla; Cabot, Gabriel; Rivera, Alba; Benito, Natividad; Segura, Concepcion; Milagro Montero, Maria; Sorli, Luisa; Tubau, Fe; Gomez-Zorrilla, Silvia; Tormo, Nuria; Dura-Navarro, Raquel; Viedma, Esther; Resino-Foz, El ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 0066-4804 (2017) DOI / 10.1128/aac.01589-17 Green published, Bronze
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Article 6-Halopyridylmethylidene Penicillin-Based Sulfones Efficiently Inactivate the Natural Resistance of Pseudomonas aeruginosa to beta-Lactam Antibiotics Vazquez-Ucha, Juan C.; Rodriguez, Diana; Lasarte-Monterrubio, Cristina; Lence, Emilio; Arca-Suarez, Jorge; Maneiro, Maria; Gato, Eva; Perez, Astrid; Martinez-Guitian, Marta; Juan, Carlos; Oliver, Antonio; Bou, German; Gonzalez-Bello, Concepcion; Beceiro, A JOURNAL OF MEDICINAL CHEMISTRY 0022-2623 (2021) DOI / 10.1021/acs.jmedchem.1c00369
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Review Pseudomonas aeruginosa epidemic high-risk clones and their association with horizontally-acquired beta-lactamases: 2020 update del Barrio-Tofino, Ester; Lopez-Causape, Carla; Oliver, Antonio INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS 0924-8579 (2020) DOI / 10.1016/j.ijantimicag.2020.106196
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Article Therapeutic Efficacy of LN-1-255 in Combination with Imipenem in Severe Infection Caused by Carbapenem-Resistant Acinetobacter baumannii Carlos Vazquez-Ucha, Juan; Martinez-Guitian, Marta; Maneiro, Maria; Conde-Perez, Kelly; Alvarez-Fraga, Laura; Torrens, Gabriel; Oliver, Antonio; Buynak, John D.; Bonomo, Robert A.; Bou, German; Gonzalez-Bello, Concepcion; Poza, Margarita; Beceiro, Alejandr ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 0066-4804 (2019) DOI / 10.1128/aac.01092-19 Green published, Bronze
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Letter Emergence of Resistance to Novel beta-Lactam-beta-Lactamase Inhibitor Combinations Due to Horizontally Acquired AmpC (FOX-4) in Pseudomonas aeruginosa Sequence Type 308 Fraile-Ribot, Pablo A.; del Rosario-Quintana, Cristobal; Lopez-Causape, Carla; Gomis-Font, Maria A.; Ojeda-Vargas, Mar; Oliver, Antonio ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 0066-4804 (2020) DOI / 10.1128/aac.02112-19 Bronze, Green published
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Review Four Decades of beta-Lactam Antibiotic Pharmacokinetics in Cystic Fibrosis Bulitta, Juergen B.; Jiao, Yuanyuan; Drescher, Stefanie K.; Oliver, Antonio; Louie, Arnold; Moya, Bartolome; Tao, Xun; Wittau, Mathias; Tsuji, Brian T.; Zavascki, Alexandre P.; Shin, Beom Soo; Drusano, George L.; Soergel, Fritz; Landersdorfer, Cornelia B. CLINICAL PHARMACOKINETICS 0312-5963 (2019) DOI / 10.1007/s40262-018-0678-x
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Article Geographical variation in therapy for bloodstream infections due to multidrug-resistant Enterobacteriaceae: a post-hoc analysis of the INCREMENT study Harris, Patrick N. A.; Pezzani, M. Diletta; Gutierrez-Gutierrez, Belen; Viale, Pierluigi; Hsueh, Po-Ren; Ruiz-Garbajosa, Patricia; Venditti, Mario; Tumbarello, Mario; Navarro-Francisco, Carolina; Calbo, Esther; Akova, Murat; Giamarellou, Helen; Oliver, Ant INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS 0924-8579 (2017) DOI / 10.1016/j.ijantimicag.2017.08.005 Green accepted
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Article In Vitro and In Vivo Activities of beta-Lactams in Combination with the Novel beta-Lactam Enhancers Zidebactam and WCK 5153 against Multidrug-Resistant Metallo-beta-Lactamase-Producing Klebsiella pneumoniae Moya, Bartolome; Barcelo, Isabel M.; Cabot, Gabriel; Torrens, Gabriel; Palwe, Snehal; Joshi, Prashant; Umarkar, Kushal; Takalkar, Swapna; Periasamy, Hariharan; Bhagwat, Sachin; Patel, Mahesh; Bou, German; Oliver, Antonio ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 0066-4804 (2019) DOI / 10.1128/aac.00128-19 Green published, Bronze
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Article Susceptibility to R-pyocins of Pseudomonas aeruginosa clinical isolates from cystic fibrosis patients Redero, Mar; Lopez-Causape, Carla; Aznar, Javier; Oliver, Antonio; Blazquez, Jesus; Prieto, Ana I. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 0305-7453 (2018) DOI / 10.1093/jac/dky261 Bronze
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Article Molecular and biochemical insights into the in vivo evolution of AmpC-mediated resistance to ceftolozane/tazobactam during treatment of an MDR Pseudomonas aeruginosa infection Arca-Suarez, Jorge; Vazquez-Ucha, Juan Carlos; Fraile-Ribot, Pablo Arturo; Lence, Emilio; Cabot, Gabriel; Martinez-Guitian, Marta; Lasarte-Monterrubio, Cristina; Rodriguez-Iglesias, Manuel; Beceiro, Alejandro; Gonzalez-Bello, Concepcion; Galan-Sanchez, Fat JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 0305-7453 (2020) DOI / 10.1093/jac/dkaa291
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Article Challenging Antimicrobial Susceptibility and Evolution of Resistance (OXA-681) during Treatment of a Long-Term Nosocomial Infection Caused by a Pseudomonas aeruginosa ST175 Clone Arca-Suarez, Jorge; Fraile-Ribot, Pablo; Carlos Vazquez-Ucha, Juan; Cabot, Gabriel; Martinez-Guitian, Marta; Lence, Emilio; Gonzalez-Bello, Concepcion; Beceiro, Alejandro; Rodriguez-Iglesias, Manuel; Galan-Sanchez, Fatima; Bou, German; Oliver, Antonio ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 0066-4804 (2019) DOI / 10.1128/aac.01110-19 Green published, Bronze
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Article Phenylboronic Acid Derivatives as Validated Leads Active in Clinical Strains Overexpressing KPC-2: A Step against Bacterial Resistance Celenza, Giuseppe; Vicario, Mattia; Bellio, Pierangelo; Linciano, Pasquale; Perilli, Mariagrazia; Oliver, Antonio; Blazquez, Jesus; Cendron, Laura; Tondi, Donatella CHEMMEDCHEM 1860-7179 (2018) DOI / 10.1002/cmdc.201700788
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Article Activity of ceftolozane/tazobactam against Pseudomonas aeruginosa and Enterobacterales isolates recovered from intensive care unit patients in Spain: The SUPERIOR multicentre study Garcia-Fernandez, Sergio; Garcia-Castillo, Maria; Bou, German; Calvo, Jorge; Cercenado, Emilia; Delgado, Mercedes; Pitart, Cristina; Mulet, Xavier; Tormo, Nuria; Lopez Mendoza, Diego; Diaz-Reganon, Jazmin; Canton, Rafael; Oliver, Antonio; Pascual, Alvaro; INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS 0924-8579 (2019) DOI / 10.1016/j.ijantimicag.2019.02.004
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Article Antibiotic resistance and population structure of cystic fibrosis Pseudomonas aeruginosa isolates from a Spanish multi-centre study Lopez-Causape, Carla; de Dios-Caballero, Juan; Cobo, Marta; Escribano, Amparo; Asensio, Oscar; Oliver, Antonio; del Campo, Rosa; Canton, Rafael INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS 0924-8579 (2017) DOI / 10.1016/j.ijantimicag.2017.03.034
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Article Pharmacodynamics of ceftazidime plus tobramycin combination dosage regimens against hypermutable Pseudomonas aeruginosa isolates at simulated epithelial lining fluid concentrations in a dynamic in vitro infection model Tait, Jessica R.; Bilal, Hajira; Kim, Tae Hwan; Oh, Abigail; Peleg, Anton Y.; Boyce, John D.; Oliver, Antonio; Bergen, Phillip J.; Nation, Roger L.; Landersdorfer, Cornelia B. JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE 2213-7165 (2021) DOI / 10.1016/j.jgar.2021.04.021 Gold
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Article Characterization of Hypermutator Pseudomonas aeruginosa Isolates from Patients with Cystic Fibrosis in Australia Rees, Vanessa E.; Lucas, Deanna S. Deveson; Lopez-Causape, Carla; Huang, Yuling; Kotsimbos, Tom; Bulitta, Jurgen B.; Rees, Murray C.; Barugahare, Adele; Peleg, Anton Y.; Nation, Roger L.; Oliver, Antonio; Boyce, John D.; Landersdorfer, Cornelia B. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 0066-4804 (2019) DOI / 10.1128/aac.02538-18 Green published, Bronze
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Article In Vivo Evolution of GES beta-Lactamases Driven by Ceftazidime/Avibactam Treatment of Pseudomonas aeruginosa Infections Fraile-Ribot, Pablo A.; Fernandez, Javier; Gomis-Font, Maria A.; Forcelledo, Lorena; Mulet, Xavier; Lopez-Causape, Carla; Oliver, Antonio ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 0066-4804 (2021) DOI / 10.1128/aac.00986-21
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Article Adding Insult to Injury: Mechanistic Basis for How AmpC Mutations Allow Pseudomonas aeruginosa To Accelerate Cephalosporin Hydrolysis and Evade Avibactam Slater, Cole L.; Winogrodzki, Judith; Fraile-Ribot, Pablo A.; Oliver, Antonio; Khajehpour, Mazdak; Mark, Brian L. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 0066-4804 (2020) DOI / 10.1128/aac.00894-20 Green published
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Article Carbapenemase-producing Pseudomonas aeruginosa in Spain: interregional dissemination of the high-risk clones ST175 and ST244 carrying bla(VIM-2), bla(VIM-1), bla(IMP-8), bla(VIM-20) and bla(KPC-2) Perez-Vazquez, Maria; Sola-Campoy, Pedro J.; Maria Zurita, Angela; Avila, Alicia; Gomez-Bertomeu, Frederic; Solis, Sonia; Lopez-Urrutia, Luis; Gonzalez-Barbera, Eva Ma; Cercenado, Emilia; Bautista, Veronica; Lara, Noelia; Aracil, Belen; Oliver, Antonio; Ca INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS 0924-8579 (2020) DOI / 10.1016/j.ijantimicag.2020.106026
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Letter Emergence of high-level and stable metronidazole resistance in Clostridioides difficile Arcay, Ricardo M.; Suarez-Bode, Loreto; Lopez-Causape, Carla; Oliver, Antonio; Mena, Ana INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS 0924-8579 (2020) DOI / 10.1016/j.ijantimicag.2019.10.011 Bronze
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Article In vitro dynamics and mechanisms of resistance development to imipenem and imipenem/relebactam in Pseudomonas aeruginosa Gomis-Font, Maria A.; Cabot, Gabriel; Sanchez-Diener, Irina; Fraile-Ribot, Pablo A.; Juan, Carlos; Moya, Bartolome; Zamorano, Laura; Oliver, Antonio JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 0305-7453 (2020) DOI / 10.1093/jac/dkaa206
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Article Evaluation of Tobramycin and Ciprofloxacin as a Synergistic Combination Against Hypermutable Pseudomonas Aeruginosa Strains via Mechanism-Based Modelling Rees, Vanessa E.; Bulitta, Jurgen B.; Oliver, Antonio; Nation, Roger L.; Landersdorfer, Cornelia B. PHARMACEUTICS (2019) DOI / 10.3390/pharmaceutics11090470 Green published, Gold
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Article Whole-genome sequence-guided PCR for the rapid identification of the Pseudomonas aeruginosa ST175 high-risk clone directly from clinical samples Cabot, Gabriel; Lara-Esbri, Paula; Mulet, Xavier; Oliver, Antonio JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 0305-7453 (2021) DOI / 10.1093/jac/dkaa528
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Article Determining beta-lactam exposure threshold to suppress resistance development in Gram-negative bacteria Tam, Vincent H.; Chang, Kai-Tai; Zhou, Jian; Ledesma, Kimberly R.; Phe, Kady; Gao, Song; Van Bambeke, Francoise; Maria Sanchez-Diaz, Ana; Zamorano, Laura; Oliver, Antonio; Canton, Rafael JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 0305-7453 (2017) DOI / 10.1093/jac/dkx001 Bronze
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Article Clinically Relevant Epithelial Lining Fluid Concentrations of Meropenem with Ciprofloxacin Provide Synergistic Killing and Resistance Suppression of Hypermutable Pseudomonas aeruginosa in a Dynamic Biofilm Model Bilal, Hajira; Bergen, Phillip J.; Tait, Jessica R.; Wallis, Steven C.; Peleg, Anton Y.; Roberts, Jason A.; Oliver, Antonio; Nation, Roger L.; Landersdorfer, Cornelia B. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 0066-4804 (2020) DOI / 10.1128/aac.00469-20 Green published
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Article Synergistic activity of fosfomycin, beta-lactams and peptidoglycan recycling inhibition against Pseudomonas aeruginosa Hamou-Segarra, Myriam; Zamorano, Laura; Vadlamani, Grishma; Chu, Mitchell; Sanchez-Diener, Irina; Juan, Carlos; Blazquez, Jesus; Hattie, Mitchell; Stubbs, Keith A.; Mark, Brian L.; Oliver, Antonio JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 0305-7453 (2017) DOI / 10.1093/jac/dkw456 Bronze
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Article Increased Antimicrobial Resistance in a Novel CMY-54 AmpC-Type Enzyme with a GluLeu(217-218) Insertion in the -Loop Jose Perez-Llarena, Francisco; Carlos Vazquez-Ucha, Juan; Kerff, Frederic; Zamorano, Laura; Miro, Elisenda; Povoa Cabral, Maria; Fleites, Ana; Lantero, Marta; Martinez-Martinez, Luis; Oliver, Antonio; Galleni, Moreno; Navarro, Ferran; Beceiro, Alejandro; B MICROBIAL DRUG RESISTANCE 1076-6294 (2018) DOI / 10.1089/mdr.2017.0017
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Article Synergistic Meropenem-Tobramycin Combination Dosage Regimens against Clinical Hypermutable Pseudomonas aeruginosa at Simulated Epithelial Lining Fluid Concentrations in a Dynamic Biofilm Model Bilal, Hajira; Bergen, Phillip J.; Kim, Tae Hwan; Chung, Seung Eun; Peleg, Anton Y.; Oliver, Antonio; Nation, Roger L.; Landersdorfer, Cornelia B. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 0066-4804 (2019) DOI / 10.1128/aac.01293-19 Green published, Bronze

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