Biology & Biochemistry


  Listando 10 trabajos del autor/autora 38
Lista de trabajos en el área Biology & Biochemistry
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Article Open-source discovery of chemical leads for next-generation chemoprotective antimalarials Antonova-Koch, Yevgeniya; Meister, Stephan; Abraham, Matthew; Luth, Madeline R.; Ottilie, Sabine; Lukens, Amanda K.; Sakata-Kato, Tomoyo; Vanaerschot, Manu; Owen, Edward; Rodriguez, Juan Carlos Jado; Maher, Steven P.; Calla, Jaeson; Plouffe, David; Zhong, SCIENCE 0036-8075 (2018) DOI / 10.1126/science.aat9446 Green published, Gold other, Green accepted
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Article Validation of the protein kinase PfCLK3 as a multistage cross-species malarial drug target Alam, Mahmood M.; Sanchez-Azqueta, Ana; Janha, Omar; Flannery, Erika L.; Mahindra, Amit; Mapesa, Kopano; Char, Aditya B.; Sriranganadane, Dev; Brancucci, Nicolas M. B.; Antonova-Koch, Yevgeniya; Crouch, Kathryn; Simwela, Nelson Victor; Millar, Scott B.; Ak SCIENCE 0036-8075 (2019) DOI / 10.1126/science.aau1682 Bronze, Green accepted
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Article Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics Cowell, Annie N.; Istvan, Eva S.; Lukens, Amanda K.; Gomez-Lorenzo, Maria G.; Vanaerschot, Manu; Sakata-Kato, Tomoyo; Flannery, Erika L.; Magistrado, Pamela; Owen, Edward; Abraham, Matthew; LaMonte, Gregory; Painter, Heather J.; Williams, Roy M.; Franco, V SCIENCE 0036-8075 (2018) DOI / 10.1126/science.aan4472 Gold other, Green accepted, Green published
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Article Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis Baragana, Beatriz; Forte, Barbara; Choi, Ryan; Hewitt, Stephen Nakazawa; Bueren-Calabuig, Juan A.; Pisco, Joao Pedro; Peet, Caroline; Dranow, David M.; Robinson, David A.; Jansen, Chimed; Norcross, Neil R.; Vinayak, Sumiti; Anderson, Mark; Brooks, Carrie F PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 0027-8424 (2019) DOI / 10.1073/pnas.1814685116 Green accepted, Green published, Gold other
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Article A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue Sonoiki, Ebere; Ng, Caroline L.; Lee, Marcus C. S.; Guo, Denghui; Zhang, Yong-Kang; Zhou, Yasheen; Alley, M. R. K.; Ahyong, Vida; Sanz, Laura M.; Jose Lafuente-Monasterio, Maria; Dong, Chen; Schupp, Patrick G.; Gut, Jiri; Legac, Jenny; Cooper, Roland A.; G NATURE COMMUNICATIONS (2017) DOI / 10.1038/ncomms14574 Gold DOAJ, Green published
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Article Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome Xie, Stanley C.; Metcalfe, Riley D.; Mizutani, Hirotake; Puhalovich, Tanya; Hanssen, Eric; Morton, Craig J.; Du, Yawei; Dogovski, Con; Huang, Shih-Chung; Ciavarri, Jeffrey; Hales, Paul; Griffin, Robert J.; Cohen, Lawrence H.; Chuang, Bei-Ching; Wittlin, Se PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 0027-8424 (2021) DOI / 10.1073/pnas.2107213118 Hybrid, Green submitted, Green published
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Article A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission Baker, David A.; Stewart, Lindsay B.; Large, Jonathan M.; Bowyer, Paul W.; Ansell, Keith H.; Jimenez-Diaz, Mar-A B.; El Bakkouri, Majida; Birchall, Kristian; Dechering, Koen J.; Bouloc, Nathalie S.; Coombs, Peter J.; Whalley, David; Harding, Denise J.; Smi NATURE COMMUNICATIONS (2017) DOI / 10.1038/s41467-017-00572-x Gold DOAJ, Green published, Green accepted
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Article High-Content Phenotypic Screen of a Focused TCAMS Drug Library Identifies Novel Disruptors of the Malaria Parasite Calcium Dynamics Chia, Wanni; Gomez-Lorenzo, Maria G.; Castellote, Isabel; Tong, Jie Xin; Chandramohanadas, Rajesh; Chu, Trang Thi Thu; Shen, Wanxiang; Go, Mei Lin; de Cozar, Cristina; Crespo, Benigno; Almela, Maria J.; Neria-Serrano, Fernando; Franco, Virginia; Gamo, Fran ACS CHEMICAL BIOLOGY 1554-8929 (2021) DOI / 10.1021/acschembio.1c00512
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Article Optimisation of 2-(N-phenyl carboxamide) triazolopyrimidine antimalarials with moderate to slow acting erythrocytic stage activity Bailey, Brodie L.; Nguyen, William; Ngo, Anna; Goodman, Christopher D.; Gancheva, Maria R.; Favuzza, Paola; Sanz, Laura M.; Gamo, Francisco-Javier; Lowes, Kym N.; McFadden, Geoffrey I.; Wilson, Danny W.; Laleu, Benoit; Brand, Stephen; Jackson, Paul F.; Cow BIOORGANIC CHEMISTRY 0045-2068 (2021) DOI / 10.1016/j.bioorg.2021.105244
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Article High-throughput microsphiltration to assess red blood cell deformability and screen for malaria transmission-blocking drugs Duez, Julien; Carucci, Mario; Garcia-Barbazan, Irene; Corral, Matias; Perez, Oscar; Luis Presa, Jesus; Henry, Benoit; Roussel, Camille; Ndour, Papa Alioune; Bahamontes Rosa, Noemi; Sanz, Laura; Gamo, Francisco-Javier; Buffet, Pierre NATURE PROTOCOLS 1754-2189 (2018) DOI / 10.1038/nprot.2018.035

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