Pharmacology & Toxicology
Listando 15 trabajos del autor/autora 38
Lista de trabajos en el área Pharmacology & Toxicology
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36
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0
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11
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Article
A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance
O'Neill, Paul M.; Amewu, Richard K.; Charman, Susan A.; Sabbani, Sunil; Gnadig, Nina F.; Straimer, Judith; Fidock, David A.; Shore, Emma R.; Roberts, Natalie L.; Wong, Michael H. -L.; Hong, W. David; Pidathala, Chandrakala; Riley, Chris; Murphy, Ben; Aljay
NATURE COMMUNICATIONS
(2017)
DOI /
10.1038/ncomms15159
Gold DOAJ, Green accepted, Green published
Mentions
4
Twitter
0
Wikipedia
5
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0
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Article
UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria
Brunschwig, Christel; Lawrence, Nina; Taylor, Dale; Abay, Efrem; Njoroge, Mathew; Basarab, Gregory S.; Le Manach, Claire; Paquet, Tanya; Cabrera, Diego Gonzalez; Nchinda, Aloysius T.; de Kock, Carmen; Wiesner, Lubbe; Denti, Paolo; Waterson, David; Blasco,
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
0066-4804 (2018)
DOI /
10.1128/aac.00012-18
Green published, Green accepted, Bronze
Mentions
23
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0
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1
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0
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Article
G6PD distribution in sub-Saharan Africa and potential risks of using chloroquine/hydroxychloroquine based treatments for COVID-19
da Rocha, Jorge E. B.; Othman, Houcemeddine; Tiemessen, Caroline T.; Botha, Gerrit; Ramsay, Michele; Masimirembwa, Collen; Adebamowo, Clement; Choudhury, Ananyo; Brandenburg, Jean-Tristan; Matshaba, Mogomotsi; Simo, Gustave; Gamo, Francisco-Javier; Hazelhu
PHARMACOGENOMICS JOURNAL
1470-269X (2021)
DOI /
10.1038/s41397-021-00242-8
Green published, Hybrid
Mentions
13
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0
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1
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0
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Article
Substituted Aminoacetamides as Novel Leads for Malaria Treatment
Norcross, Neil R.; Wilson, Caroline; Baragana, Beatriz; Hallyburton, Irene; Osuna-Cabello, Maria; Norval, Suzanne; Riley, Jennifer; Fletcher, Daniel; Sinden, Robert; Delves, Michael; Ruecker, Andrea; Duffy, Sandra; Meister, Stephan; Antonova-Koch, Yevgeniy
CHEMMEDCHEM
1860-7179 (2019)
DOI /
10.1002/cmdc.201900329
Green accepted, Green published, Gold other
Mentions
17
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0
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0
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Article
Prioritization of Molecular Targets for Antimalarial Drug Discovery
Forte, Barbara; Ottilie, Sabine; Plater, Andrew; Campo, Brice; Dechering, Koen J.; Javier Gamo, Francisco; Goldberg, Daniel E.; Istvan, Eva S.; Lee, Marcus; Lukens, Amanda K.; McNamara, Case W.; Niles, Jacquin C.; Okombo, John; Pasaje, Charisse Flerida A.;
ACS INFECTIOUS DISEASES
2373-8227 (2021)
DOI /
10.1021/acsinfecdis.1c00322
Green submitted, Hybrid
Mentions
13
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0
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0
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0
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Article
Novel Antimalarial Tetrazoles and Amides Active against the Hemoglobin Degradation Pathway in Plasmodium falciparum
Lawong, Aloysus; Gahalawat, Suraksha; Okombo, John; Striepen, Josefine; Yeo, Tomas; Mok, Sachel; Deni, Ioanna; Bridgford, Jessica L.; Niederstrasser, Hanspeter; Zhou, Anwu; Posner, Bruce; Wittlin, Sergio; Javier Gamo, Francisco; Crespo, Benigno; Churchyard
JOURNAL OF MEDICINAL CHEMISTRY
0022-2623 (2021)
DOI /
10.1021/acs.jmedchem.0c02022
Mentions
5
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1
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0
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0
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Article
A human microdose study of the antimalarial drug GSK3191607 in healthy volunteers
Okour, Malek; Derimanov, Geo; Barnett, Rodger; Fernandez, Esther; Ferrer, Santiago; Gresham, Stephanie; Hossain, Mohammad; Gamo, Francisco-Javier; Koh, Gavin; Pereira, Adrian; Rolfe, Katie; Wong, Deborah; Young, Graeme; Rami, Harshad; Haselden, John
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
0306-5251 (2018)
DOI /
10.1111/bcp.13476
Green published, Bronze
Mentions
6
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0
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0
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0
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Article
Expanding Bromodomain Targeting into Neglected Parasitic Diseases
Tallant, Cynthia; Bamborough, Paul; Chung, Chun-wa; Gamo, Francisco Javier; Kirkpatrick, Robert; Larminie, Chris; Martin, Julio; Prinjha, Rab; Rioja, Inmaculada; Simola, Daniel F.; Gabarro, Raquel; Calderon, Felix
ACS INFECTIOUS DISEASES
2373-8227 (2021)
DOI /
10.1021/acsinfecdis.1c00387
Mentions
3
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0
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0
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0
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Article
Overexpression of plasmepsin II and plasmepsin III does not directly cause reduction in Plasmodium falciparum sensitivity to artesunate, chloroquine and piperaquine
Loesbanluechai, Duangkamon; Kotanan, Namfon; de Cozar, Cristina; Kochakarn, Theerarat; Ansbro, Megan R.; Chotivanich, Kesinee; White, Nicholas J.; Wilairat, Prapon; Lee, Marcus C. S.; Javier Gamo, Francisco; Maria Sanz, Laura; Chookajorn, Thanat; Kumpornsi
INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE
2211-3207 (2019)
DOI /
10.1016/j.ijpddr.2018.11.004
Gold DOAJ, Green published
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0
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0
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0
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Article
Synthesis, Profiling, and in Vivo Evaluation of Cyclopeptides Containing N-Methyl Amino Acids as Antiplasmodial Agents
Fagundez, Catherine; Sellanes, Diver; Pena, Stella; Scarone, Laura; Aguiar, Anna C. C.; de Souza, Juliana O.; Guido, Rafael V. C.; Stewart, Lindsay; Yardley, Vanessa; Ottilie, Sabine; Winzeler, Elizabeth A.; Gamo, Francisco-J.; Sanz, Laura M.; Serra, Glori
ACS MEDICINAL CHEMISTRY LETTERS
1948-5875 (2019)
DOI /
10.1021/acsmedchemlett.8b00543
Green published
Mentions
2
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0
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0
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Article
The Discovery of Novel Antimalarial Aminoxadiazoles as a Promising Nonendoperoxide Scaffold
Sandoval, Elena; Jose Lafuente-Monasterio, Maria; Almela, Maria J.; Castaneda, Pablo; Jimenez Diaz, Maria Belen; Martinez-Martinez, Maria S.; Vidal, Jaume; Angulo-Barturen, Inigo; Bamborough, Paul; Burrows, Jeremy; Cammack, Nicholas; Chaparro, Maria J.; Co
JOURNAL OF MEDICINAL CHEMISTRY
0022-2623 (2017)
DOI /
10.1021/acs.jmedchem.6b01441
Mentions
1
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0
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0
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0
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Article
A novel class of fast-acting antimalarial agents: Substituted 15-membered azalides
Peric, Mihaela; Pesic, Dijana; Alihodzic, Sulejman; Fajdetic, Andrea; Herreros, Esperanza; Gamo, Francisco Javier; Angulo-Barturen, Inigo; Jimenez-Diaz, Maria Belen; Ferrer-Bazaga, Santiago; Martinez, Maria S.; Gargallo-Viola, Domingo; Mathis, Amanda; Kess
BRITISH JOURNAL OF PHARMACOLOGY
0007-1188 (2020)
DOI /
10.1111/bph.15292
Gold other
Mentions
1
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0
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0
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0
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Article
Identification of Collateral Sensitivity to Dihydroorotate Dehydrogenase Inhibitors in Plasmodium falciparum
Ross, Leila Saxby; Lafuente-Monasterio, Maria Jose; Sakata-Kato, Tomoyo; Mandt, Rebecca E. K.; Gamo, Francisco Javier; Wirth, Dyann F.; Lukens, Amanda K.
ACS INFECTIOUS DISEASES
2373-8227 (2018)
DOI /
10.1021/acsinfecdis.7b00217
Green published, Green accepted, Hybrid
Mentions
1
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0
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0
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0
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Article
Benzoxaborole Antimalarial Agents. Part 5. Lead Optimization of Novel Amide Pyrazinyloxy Benzoxaboroles and Identification of a Preclinical Candidate
Zhang, Yong-Kang; Plattner, Jacob J.; Easom, Eric E.; Jacobs, Robert T.; Guo, Denghui; Freund, Yvonne R.; Berry, Pamela; Ciaravino, Vic; Erve, John C. L.; Rosenthal, Philip J.; Campo, Brice; Gamo, Francisco-Javier; Sanz, Laura M.; Cao, Jianxin
JOURNAL OF MEDICINAL CHEMISTRY
0022-2623 (2017)
DOI /
10.1021/acs.jmedchem.7b00621
Mentions
2
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0
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0
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Article
High Throughput Screening to Identify Selective and Nonpeptidomimetic Proteasome Inhibitors As Antimalarials
Mata-Cantero, Lydia; Xie, Stanley C.; Garcia, Mercedes; Coyle, Joanne; Fernandez, Raquel; Cortes Cabrera, Alvaro; Gillett, David L.; Crespo, Benigno; Gamo, Francisco-Javier; Fernandez, Esther; Tilley, Leann; Gomez-Lorenzo, Maria G.
ACS INFECTIOUS DISEASES
2373-8227 (2021)
DOI /
10.1021/acsinfecdis.1c00110
Gold other
