Pharmacology & Toxicology
Listando 16 trabajos del autor/autora 38
Lista de trabajos en el área Pharmacology & Toxicology
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14
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10
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Article
Pharmacological Inhibition of Soluble Epoxide Hydrolase as a New Therapy for Alzheimer's Disease
Grinan-Ferre, Christian; Codony, Sandra; Pujol, Eugenia; Yang, Jun; Leiva, Rosana; Escolano, Carmen; Puigoriol-Illamola, Dolors; Companys-Alemany, Julia; Corpas, Ruben; Sanfeliu, Coral; Perez, Belen; Isabel Loza, M.; Brea, Jose; Morisseau, Christophe; Hamm
NEUROTHERAPEUTICS
1933-7213 (2020)
DOI /
10.1007/s13311-020-00854-1
Green accepted, Bronze, Green published, Green submitted
Mentions
20
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0
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10
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0
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Article
Benzofuranyl-2-imidazoles as imidazoline I-2 receptor ligands for Alzheimer's disease
Rodriguez-Arevalo, Sergio; Bagan, Andrea; Grinan-Ferre, Christian; Vasilopoulou, Foteini; Pallas, Merce; Brocos-Mosquera, Iria; Callado, Luis F.; Isabel Loza, M.; Martinez, Anton L.; Brea, Jose; Perez, Belen; Molins, Elies; De Jonghe, Steven; Daelemans, Di
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
0223-5234 (2021)
DOI /
10.1016/j.ejmech.2021.113540
Mentions
65
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8
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Article
Bicyclic alpha-Iminophosphonates as High Affinity Imidazoline I-2 Receptor Ligands for Alzheimer's Disease
Abas, Sonia; Rodriguez-Arevalo, Sergio; Bagan, Andrea; Grinan-Ferre, Christian; Vasilopoulou, Foteini; Brocos-Mosquera, Iria; Muguruza, Carolina; Perez, Belen; Molins, Elies; Javier Luque, F.; Perez-Lozano, Pilar; De Jonghe, Steven; Daelemans, Dirk; Naesen
JOURNAL OF MEDICINAL CHEMISTRY
0022-2623 (2020)
DOI /
10.1021/acs.jmedchem.9b02080
Green accepted, Green submitted
Mentions
36
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1
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Article
Centrally Active Multitarget Anti-Alzheimer Agents Derived from the Antioxidant Lead CR-6
Javier Perez-Areales, F.; Garrido, Maria; Aso, Ester; Bartolini, Manuela; De Simone, Angela; Espargaro, Alba; Ginex, Tiziana; Sabate, Raimon; Perez, Belen; Andrisano, Vincenza; Puigoriol-Illamola, Dolors; Pallas, Merce; Javier Luque, F.; Isabel Loza, Maria
JOURNAL OF MEDICINAL CHEMISTRY
0022-2623 (2020)
DOI /
10.1021/acs.jmedchem.0c00528
Mentions
4
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1
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Article
Behavioral and Cognitive Improvement Induced by Novel Imidazoline I-2 Receptor Ligands in Female SAMP8 Mice
Grinan-Ferre, Christian; Vasilopoulou, Foteini; Abas, Sonia; Rodriguez-Arevalo, Sergio; Bagan, Andrea; Sureda, Francesc X.; Perez, Belen; Callado, Luis F.; Garcia-Sevilla, Jesus A.; Julia Garcia-Fuster, M.; Escolano, Carmen; Pallas, Merce
NEUROTHERAPEUTICS
1933-7213 (2019)
DOI /
10.1007/s13311-018-00681-5
Bronze, Green published, Green accepted
Mentions
9
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0
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1
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0
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Article
A novel class of multitarget anti-Alzheimer benzohomoadamantane- chlorotacrine hybrids modulating cholinesterases and glutamate NMDA receptors
Javier Perez-Areales, F.; Turcu, Andreea L.; Barniol-Xicota, Marta; Pont, Caterina; Pivetta, Deborah; Espargaro, Alba; Bartolini, Manuela; De Simone, Angela; Andrisano, Vincenza; Perez, Beier'; Sabate, Raimon; Sureda, Francesc X.; Vazquez, Santiago; Munoz-
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
0223-5234 (2019)
DOI /
10.1016/j.ejmech.2019.07.051
Green accepted
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1
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1
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1
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Review
Behavioural effects of novel multitarget anticholinesterasic derivatives in Alzheimer's disease
Gimenez-Llort, Lydia; Ratia, Miriam; Perez, Belen; Camps, Pelayo; Munoz-Torrero, Diego; Badia, Albert; Clos, M. Victoria
BEHAVIOURAL PHARMACOLOGY
0955-8810 (2017)
DOI /
10.1097/fbp.0000000000000292
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0
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0
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1
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Article
Design, synthesis and multitarget biological profiling of second-generation anti-Alzheimer rhein-huprine hybrids
Javier Perez-Areales, Francisco; Betari, Nibal; Viayna, Antonio; Pont, Caterina; Espargaro, Alba; Bartolini, Manuela; De Simone, Angela; Rinaldi Alvarenga, Jose Fernando; Perez, Belen; Sabate, Raimon; Maria Lamuela-Raventos, Rosa; Andrisano, Vincenza; Javi
FUTURE MEDICINAL CHEMISTRY
1756-8919 (2017)
DOI /
10.4155/fmc-2017-0049
Mentions
19
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0
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0
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Article
From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects
Pont, Caterina; Ginex, Tiziana; Grinan-Ferre, Christian; Scheiner, Matthias; Mattellone, Alexia; Martinez, Noemi; Arce, Elsa M.; Soriano-Fernandez, Yolanda; Naldi, Marina; De Simone, Angela; Barenys, Marta; Gomez-Catalan, Jesus; Perez, Belen; Sabate, Raimo
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
0223-5234 (2021)
DOI /
10.1016/j.ejmech.2021.113779
Hybrid
Mentions
20
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Article
Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP/PS1 Mice
Viayna, Elisabet; Coquelle, Nicolas; Cieslikiewicz-Bouet, Monika; Cisternas, Pedro; Oliva, Carolina A.; Sanchez-Lopez, Elena; Ettcheto, Miren; Bartolini, Manuela; De Simone, Angela; Ricchini, Mattia; Rendina, Marisa; Pons, Megane; Firuzi, Omidreza; Perez,
JOURNAL OF MEDICINAL CHEMISTRY
0022-2623 (2021)
DOI /
10.1021/acs.jmedchem.0c01775
Mentions
3
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0
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1
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Article
Functional characterization of multifunctional ligands targeting acetylcholinesterase and alpha 7 nicotinic acetylcholine receptor
Cieslikiewicz-Bouet, Monika; Naldi, Marina; Bartolini, Manuela; Perez, Belen; Servent, Denis; Jean, Ludovic; Araoz, Romulo; Renard, Pierre-Yves
BIOCHEMICAL PHARMACOLOGY
0006-2952 (2020)
DOI /
10.1016/j.bcp.2020.114010
Mentions
7
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0
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0
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Article
2-Oxaadamant-1-yl Ureas as Soluble Epoxide Hydrolase Inhibitors: In Vivo Evaluation in a Murine Model of Acute Pancreatitis
Codony, Sandra; Pujol, Eugenia; Pizarro, Javier; Feixas, Ferran; Valverde, Elena; Isabel Loza, M.; Brea, Jose M.; Saez, Elena; Oyarzabal, Julen; Pineda-Lucena, Antonio; Perez, Belen; Perez, Concepcion; Isabel Rodriguez-Franco, Maria; Leiva, Rosana; Osuna,
JOURNAL OF MEDICINAL CHEMISTRY
0022-2623 (2020)
DOI /
10.1021/acs.jmedchem.0c00310
Green accepted, Green submitted
Mentions
3
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0
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0
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Article
Oxidative Stress and Inflammatory Markers in Abdominal Aortic Aneurysm
Sanchez-Infantes, David; Nus, Meritxell; Navas-Madronal, Miquel; Fite, Joan; Perez, Belen; Barros-Membrilla, Antonio J.; Soto, Begona; Martinez-Gonzalez, Jose; Camacho, Mercedes; Rodriguez, Cristina; Mallat, Ziad; Galan, Maria
ANTIOXIDANTS
(2021)
DOI /
10.3390/antiox10040602
Gold DOAJ, Green published
Mentions
0
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1
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0
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Article
Huprine X Attenuates The Neurotoxicity Induced by Kainic Acid, Especially Brain Inflammation
Relat, Julia; Perez, Belen; Camps, Pelayo; Munoz-Torrero, Diego; Badia, Albert; Victoria Clos, M.
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
1742-7835 (2018)
DOI /
10.1111/bcpt.12852
Bronze
Mentions
2
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Article
Pharmacology and preclinical validation of a novel anticancer compound targeting PEPCK-M
Arago, Marc; Moreno-Felici, Juan; Abas, Sonia; Rodriguez-Arevalo, Sergio; Hyrossova, Petra; Figueras, Agnes; Vinals, Francesc; Perez, Belen; Loza, Maria, I; Brea, Jose; Latorre, Pedro; Carrodeguas, Jose A.; Garcia-Roves, Pablo M.; Galdeano, Carlos; Ginex,
BIOMEDICINE & PHARMACOTHERAPY
0753-3322 (2020)
DOI /
10.1016/j.biopha.2019.109601
Gold other
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1
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Article
Design, synthesis and in vivo study of novel pyrrolidine-based 11 beta-HSD1 inhibitors for age-related cognitive dysfunction
Leiva, Rosana; Grinan-Ferre, Christian; Seira, Constanti; Valverde, Elena; McBride, Andrew; Binnie, Margaret; Perez, Belen; Javier Luque, F.; Pallas, Merce; Bidon-Chanal, Axel; Webster, Scott P.; Vazquez, Santiago
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
0223-5234 (2017)
DOI /
10.1016/j.ejmech.2017.08.003
Green submitted
