Pharmacology & Toxicology

Listando 24 trabajos del autor/autora 38

Lista de trabajos en el área Pharmacology & Toxicology

Mentions 21 Twitter 0 Wikipedia 1 News 0 Policy

Article Tau-Centric Multitarget Approach for Alzheimer's Disease: Development of First-in-Class Dual Glycogen Synthase Kinase 3 beta and Tau-Aggregation Inhibitors Gandini, Annachiara; Bartolini, Manuela; Tedesco, Daniele; Martinez-Gonzalez, Loreto; Roca, Carlos; Campillo, Nuria E.; Zaldivar-Diez, Josefa; Perez, Concepcion; Zuccheri, Giampaolo; Miti, Andrea; Feoli, Alessandra; Castellano, Sabrina; Petralla, Sabrina; JOURNAL OF MEDICINAL CHEMISTRY 0022-2623 (2018) DOI / 10.1021/acs.jmedchem.8b00610

Mentions 26 Twitter 0 Wikipedia 0 News 0 Policy

Article From the Design to the In Vivo Evaluation of Benzohomoadamantane-Derived Soluble Epoxide Hydrolase Inhibitors for the Treatment of Acute Pancreatitis Codony, Sandra; Calvo-Tusell, Carla; Valverde, Elena; Osuna, Silvia; Morisseau, Christophe; Isabel Loza, M.; Brea, Jose; Perez, Concepcion; Isabel Rodriguez-Franco, Maria; Pizarro-Delgado, Javier; Corpas, Ruben; Grinan-Ferre, Christian; Pallas, Merce; Sanf JOURNAL OF MEDICINAL CHEMISTRY 0022-2623 (2021) DOI / 10.1021/acs.jmedchem.0c01601

Mentions 4 Twitter 0 Wikipedia 1 News 0 Policy

Article Structure-Based Design of Potent Selective Nanomolar Type-II Inhibitors of Glycogen Synthase Kinase-3 beta Davies, Matthew P.; Benitez, Rocio; Perez, Concepcion; Jakupovic, Sven; Welsby, Philip; Rzepecka, Klaudia; Alder, Jane; Davidson, Colin; Martinez, ANA; Hayes, Joseph M. JOURNAL OF MEDICINAL CHEMISTRY 0022-2623 (2021) DOI / 10.1021/acs.jmedchem.0c01568

Mentions 2 Twitter 0 Wikipedia 1 News 0 Policy

Article Novel Curcumin-Diethyl Fumarate Hybrid as a Dualistic GSK-3 beta Inhibitor/Nrf2 Inducer for the Treatment of Parkinson's Disease Di Martino, Rita Maria Concetta; Pruccoli, Letizia; Bisi, Alessandra; Gobbi, Silvia; Rampa, Angela; Martinez, ANA; Perez, Concepcion; Martinez-Gonzalez, Loreto; Paglione, Maria; Di Schiavi, Elia; Seghetti, Francesca; Tarozzi, Andrea; Belluti, Federica ACS CHEMICAL NEUROSCIENCE 1948-7193 (2020) DOI / 10.1021/acschemneuro.0c00363

Mentions 19 Twitter 0 Wikipedia 0 News 0 Policy

Article Optical control of muscular nicotinic channels with azocuroniums, photoswitchable azobenzenes bearing two N-methyl-N-carbocyclic quaternary ammonium groups Herrera-Arozamena, Clara; Estrada-Valencia, Martin; Marti-Mari, Olaia; Perez, Concepcion; Revenga, Mario de la Fuente; Villalba-Galea, Carlos A.; Isabel Rodriguez-Franco, Maria EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 0223-5234 (2020) DOI / 10.1016/j.ejmech.2020.112403

Mentions 2 Twitter 0 Wikipedia 1 News 0 Policy

Article New flavonoid - N,N-dibenzyl(N-methyl)amine hybrids: Multi-target-directed agents for Alzheimer ' s disease endowed with neurogenic properties Estrada-Valencia, Martin; Herrera-Arozamena, Clara; Perez, Concepcion; Vina, Dolores; Morales-Garcia, Jose A.; Perez-Castillo, Ana; Ramos, Eva; Romero, Alejandro; Laurini, Erik; Pricl, Sabrina; Isabel Rodriguez-Franco, Maria JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 1475-6366 (2019) DOI / 10.1080/14756366.2019.1581184 Gold DOAJ, Green published

Mentions 1 Twitter 0 Wikipedia 1 News 0 Policy

Article 1-Aryl-3-(4-methoxybenzyl)ureas as potentially irreversible glycogen synthase kinase 3 inhibitors: Synthesis and biological evaluation Venter, Jana; Perez, Concepcion; van Otterlo, Willem A. L.; Martinez, ANA; Blackie, Margaret A. L. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 0960-894X (2019) DOI / 10.1016/j.bmcl.2019.04.049 Green submitted

Mentions 1 Twitter 0 Wikipedia 1 News 0 Policy

Article Targeting nuclear protein TDP-43 by cell division cycle kinase 7 inhibitors: A new therapeutic approach for amyotrophic lateral Rojas-Prats, Elisa; Martinez-Gonzalez, Loreto; Gonzalo-Consuegra, Claudia; Liachko, Nicole F.; Perez, Concepcion; Ramirez, David; Kraemer, Brian C.; Martin-Requero, Angeles; Perez, Daniel, I; Gil, Carmen; de Lago, Eva; Martinez, ANA EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 0223-5234 (2021) DOI / 10.1016/j.ejmech.2020.112968

Mentions 3 Twitter 0 Wikipedia 0 News 0 Policy

Article Multi-target-directed ligands for Alzheimer's disease: Discovery of chromone-based monoamine oxidase/cholinesterase inhibitors Reis, Joana; Cagide, Fernando; Estrada Valencia, Martin; Teixeira, Jose; Bagetta, Donatella; Perez, Concepcion; Uriarte, Eugenio; Oliveira, Paulo J.; Ortuso, Francesco; Alcaro, Stefano; Isabel Rodriguez-Franco, Maria; Borges, Fernanda EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 0223-5234 (2018) DOI / 10.1016/j.ejmech.2018.07.056

Mentions 0 Twitter 0 Wikipedia 1 News 0 Policy

Article Enzymatic and solid-phase synthesis of new donepezil-based L-and D-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer ' s disease and cerebral ischemia Monjas, Leticia; Arce, Mariana P.; Leon, Rafael; Egea, Javier; Perez, Concepcion; Villarroya, Mercedes; Lopez, Manuela G.; Gil, Carmen; Conde, Santiago; Isabel Rodriguez-Franco, Maria EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 0223-5234 (2017) DOI / 10.1016/j.ejmech.2017.02.034 Green submitted

Mentions 0 Twitter 0 Wikipedia 1 News 0 Policy

Article 3-(Benzyloxy)-1-(5-[F-18] fluoropentyl)-5-nitro-1H-indazole: a PET radiotracer to measure acetylcholinesterase in brain Fernandez, Soledad; Giglio, Javier; Reyes, Ana Laura; Damian, Andres; Perez, Concepcion; Perez, Daniel I.; Gonzalez, Mercedes; Oliver, Patricia; Rey, Ana; Engler, Henry; Cerecetto, Hugo FUTURE MEDICINAL CHEMISTRY 1756-8919 (2017) DOI / 10.4155/fmc-2017-0023

Mentions 9 Twitter 0 Wikipedia 0 News 0 Policy

Article Tuning melatonin receptor subtype selectivity in oxadiazolone-based analogues: Discovery of QR2 ligands and NRF2 activators with neurogenic properties Herrera-Arozamena, Clara; Estrada-Valencia, Martin; Perez, Concepcion; Lagartera, Laura; Morales-Garcia, Jose A.; Perez-Castillo, Ana; Felipe Franco-Gonzalez, Juan; Michaiska, Patrycja; Duarte, Pablo; Leon, Rafael; Lopez, Manuela G.; Mills, Alberto; Gago, EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 0223-5234 (2020) DOI / 10.1016/j.ejmech.2020.112090 Green published, Hybrid

Mentions 0 Twitter 0 Wikipedia 1 News 0 Policy

Article Highly potent and selective aryl-1,2,3-triazolyl benzylpiperidine inhibitors toward butyrylcholinesterase in Alzheimer's disease de Andrade, Peterson; Mantoani, Susimaire P.; Goncalves Nunes, Paulo Sergio; Magadan, Carlos Roca; Perez, Concepcion; Xavier, Danilo Jordao; Sakamoto Hojo, Elza Tiemi; Campillo, Nuria E.; Martinez, ANA; Carvalho, Ivone BIOORGANIC & MEDICINAL CHEMISTRY 0968-0896 (2019) DOI / 10.1016/j.bmc.2018.12.030

Mentions 11 Twitter 0 Wikipedia 0 News 0 Policy

Article Identification of new allosteric sites and modulators of AChE through computational and experimental tools Roca, Carlos; Requena, Carlos; Sebastian-Perez, Victor; Malhotra, Sony; Radoux, Chris; Perez, Concepcion; Martinez, ANA; Antonio Paez, Juan; Blundell, Tom L.; Campillo, Nuria E. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 1475-6366 (2018) DOI / 10.1080/14756366.2018.1476502 Green published, Gold

Mentions 7 Twitter 0 Wikipedia 0 News 0 Policy

Article New cannabinoid receptor antagonists as pharmacological tool Gonzalez-Naranjo, Pedro; Perez, Concepcion; Giron, Rocio; Sanchez-Robles, Eva M.; Martin-Fontelles, Maria, I; Carrillo-Lopez, Natalia; Martin-Virgala, Julia; Naves, Manuel; Campillo, Nuria E.; Paez, Juan A. BIOORGANIC & MEDICINAL CHEMISTRY 0968-0896 (2020) DOI / 10.1016/j.bmc.2020.115672

Mentions 7 Twitter 0 Wikipedia 0 News 0 Policy

Article 2-Oxaadamant-1-yl Ureas as Soluble Epoxide Hydrolase Inhibitors: In Vivo Evaluation in a Murine Model of Acute Pancreatitis Codony, Sandra; Pujol, Eugenia; Pizarro, Javier; Feixas, Ferran; Valverde, Elena; Isabel Loza, M.; Brea, Jose M.; Saez, Elena; Oyarzabal, Julen; Pineda-Lucena, Antonio; Perez, Belen; Perez, Concepcion; Isabel Rodriguez-Franco, Maria; Leiva, Rosana; Osuna, JOURNAL OF MEDICINAL CHEMISTRY 0022-2623 (2020) DOI / 10.1021/acs.jmedchem.0c00310 Green accepted, Green submitted

Mentions 4 Twitter 0 Wikipedia 0 News 0 Policy

Article A Triazolotriazine-Based Dual GSK-3 beta/CK-1 delta Ligand as a Potential Neuroprotective Agent Presenting Two Different Mechanisms of Enzymatic Inhibition Redenti, Sara; Marcovich, Irene; De Vita, Teresa; Perez, Concepcion; De Zorzi, Rita; Demitri, Nicola; Perez, Daniel I.; Bottegoni, Giovanni; Bisignano, Paola; Bissaro, Maicol; Moro, Stefano; Martinez, ANA; Storici, Paola; Spalluto, Giampiero; Cavalli, Andr CHEMMEDCHEM 1860-7179 (2019) DOI / 10.1002/cmdc.201800778

Mentions 4 Twitter 0 Wikipedia 0 News 0 Policy

Article Indazolylketones as new multitarget cannabinoid drugs Gonzalez-Naranjo, Pedro; Perez-Macias, Natalia; Perez, Concepcion; Roca, Carlos; Vaca, Gabriela; Giron, Rocio; Sanchez-Robles, Eva; Isabel Martin-Fontelles, Maria; de Ceballos, Maria L.; Martin-Requero, Angeles; Campillo, Nuria E.; Paez, Juan A. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 0223-5234 (2019) DOI / 10.1016/j.ejmech.2019.01.030

Mentions 3 Twitter 0 Wikipedia 0 News 0 Policy

Article Subtly Modulating Glycogen Synthase Kinase 3 beta: Allosteric Inhibitor Development and Their Potential for the Treatment of Chronic Diseases Palomo, Valle; Perez, Daniel I.; Roca, Carlos; Anderson, Cara; Rodriguez-Muela, Natalia; Perez, Concepcion; Morales-Garcia, Jose A.; Reyes, Julio A.; Campillo, Nuria E.; Perez-Castillo, Ana M.; Rubin, Lee L.; Timchenko, Lubov; Gil, Carmen; Martinez, ANA JOURNAL OF MEDICINAL CHEMISTRY 0022-2623 (2017) DOI / 10.1021/acs.jmedchem.7b00395