Clinical Medicine

Listando 37 trabajos del autor/autora 38

Lista de trabajos en el área Clinical Medicine

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Article Encorafenib plus binimetinib versus vemurafenib or encorafenib in patients with BRAF-mutant melanoma (COLUMBUS): a multicentre, open-label, randomised phase 3 trial Dummer, Reinhard; Ascierto, Paolo A.; Gogas, Helen J.; Arance, Ana; Mandala, Mario; Liszkay, Gabriella; Garbe, Claus; Schadendorf, Dirk; Krajsova, Ivana; Gutzmer, Ralf; Chiarion-Sileni, Vanna; Dutriaux, Caroline; de Groot, Jan Willem B.; Yamazaki, Naoya; L LANCET ONCOLOGY 1470-2045 (2018) DOI / 10.1016/s1470-2045(18)30142-6 Green accepted

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Article Overall survival in patients with BRAF-mutant melanoma receiving encorafenib plus binimetinib versus vemurafenib or encorafenib (COLUMBUS): a multicentre, open-label, randomised, phase 3 trial Dummer, Reinhard; Ascierto, Paolo A.; Gogas, Helen J.; Arance, Ana; Mandala, Mario; Liszkay, Gabriella; Garbe, Claus; Schadendorf, Dirk; Krajsova, Ivana; Gutzmer, Ralf; Sileni, Vanna Chiarion; Dutriaux, Caroline; de Groot, Jan Willem B.; Yamazaki, Naoya; L LANCET ONCOLOGY 1470-2045 (2018) DOI / 10.1016/s1470-2045(18)30497-2

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Article Association of BRAF V600E/K Mutation Status and Prior BRAF/MEK Inhibition With Pembrolizumab Outcomes in Advanced Melanoma Pooled Analysis of 3 Clinical Trials Puzanov, Igor; Ribas, Antoni; Robert, Caroline; Schachter, Jacob; Nyakas, Marta; Daud, Adil; Arance, Ana; Carlino, Matteo S.; O'Day, Steven J.; Long, Georgina, V; Margolin, Kim A.; Dummer, Reinhard; Schadendorf, Dirk; Lutzky, Jose; Ascierto, Paolo A.; Tarh JAMA ONCOLOGY 2374-2437 (2020) DOI / 10.1001/jamaoncol.2020.2288

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Article Pembrolizumab versus ipilimumab in advanced melanoma (KEYNOTE-006): post-hoc 5-year results from an open-label, multicentre, randomised, controlled, phase 3 study Robert, Caroline; Ribas, Antoni; Schachter, Jacob; Arance, Ana; Grob, Jean-Jacques; Mortier, Laurent; Daud, Adil; Carlino, Matteo S.; McNeil, Catriona M.; Lotem, Michal; Larkin, James M. G.; Lorigan, Paul; Neyns, Bart; Blank, Christian U.; Petrella, Teresa LANCET ONCOLOGY 1470-2045 (2019) DOI / 10.1016/s1470-2045(19)30388-2

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Article Pembrolizumab versus ipilimumab for advanced melanoma: final overall survival results of a multicentre, randomised, open-label phase 3 study (KEYNOTE-006) Schachter, Jacob; Ribas, Antoni; Long, Georgina V.; Arance, Ana; Grob, Jean-Jacques; Mortier, Laurent; Daud, Adil; Carlino, Matteo S.; McNeil, Catriona; Lotem, Michal; Larkin, James; Lorigan, Paul; Neyns, Bart; Blank, Christian; Petrella, Teresa M.; Hamid, LANCET 0140-6736 (2017) DOI / 10.1016/s0140-6736(17)31601-x

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Article Adjuvant nivolumab versus ipilimumab in resected stage IIIB-C and stage IV melanoma (CheckMate 238): 4-year results from a multicentre, double-blind, randomised, controlled, phase 3 trial Ascierto, Paolo A.; Del Vecchio, Michele; Mandala, Mario; Gogas, Helen; Arance, Ana M.; Dalle, Stephane; Cowey, C. Lance; Schenker, Michael; Grob, Jean-Jacques; Chiarion-Sileni, Vanna; Marquez-Rodas, Ivan; Butler, Marcus O.; Maio, Michele; Middleton, Mark LANCET ONCOLOGY 1470-2045 (2020) DOI / 10.1016/s1470-2045(20)30494-0

Mentions 73 Twitter 0 Wikipedia 2 News 0 Policy

Article Immune-Related Gene Expression Profiling After PD-1 Blockade in Non-Small Cell Lung Carcinoma, Head and Neck Squamous Cell Carcinoma, and Melanoma Prat, Aleix; Navarro, Alejandro; Pare, Laia; Reguart, Noemi; Galvan, Patricia; Pascual, Tomas; Martinez, Alex; Nuciforo, Paolo; Comerma, Laura; Alos, Llucia; Pardo, Nuria; Cedres, Susana; Fan, Cheng; Parker, Joel S.; Gaba, Lydia; Victoria, Ivan; Vinolas, N CANCER RESEARCH 0008-5472 (2017) DOI / 10.1158/0008-5472.can-16-3556 Bronze

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Article Epacadostat plus pembrolizumab versus placebo plus pembrolizumab in patients with unresectable or metastatic melanoma (ECHO-301/KEYNOTE-252): a phase 3, randomised, double-blind study Long, Georgina, V; Dummer, Reinhard; Humid, Omid; Gajewski, Thomas F.; Caglevic, Christian; Dalle, Stephan; Arance, Ana; Carlino, Matteo S.; Grob, Jean-Jacques; Kim, Tae Min; Demidov, Lev; Robert, Caroline; Larkin, James; Anderson, James R.; Maleski, Janet LANCET ONCOLOGY 1470-2045 (2019) DOI / 10.1016/s1470-2045(19)30274-8

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Article Discontinuation of anti-PD-1 antibody therapy in the absence of disease progression or treatment limiting toxicity: clinical outcomes in advanced melanoma Jansen, Y. J. L.; Rozeman, E. A.; Mason, R.; Goldinger, S. M.; Foppen, M. H. Geukes; Hoejberg, L.; Schmidt, H.; van Thienen, J., V; Haanen, J. B. A. G.; Tiainen, L.; Svane, I. M.; Makela, S.; Seremet, T.; Arance, A.; Dummer, R.; Bastholt, L.; Nyakas, M.; S ANNALS OF ONCOLOGY 0923-7534 (2019) DOI / 10.1093/annonc/mdz110 Gold other, Green published

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Article SEOM clinical guideline for the management of immune-related adverse events in patients treated with immune checkpoint inhibitors (2019) Majem, M.; Garcia-Martinez, E.; Martinez, M.; Munoz-Couselo, E.; Rodriguez-Abreu, D.; Alvarez, R.; Arance, A.; Berrocal, A.; de la Cruz-Merino, L.; Lopez-Martin, J. A. CLINICAL & TRANSLATIONAL ONCOLOGY 1699-048X (2020) DOI / 10.1007/s12094-019-02273-x Gold other

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Article Association between PD1 mRNA and response to anti-PD1 monotherapy across multiple cancer types Pare, L.; Pascual, T.; Segui, E.; Teixido, C.; Gonzalez-Cao, M.; Galvan, P.; Rodriguez, A.; Gonzalez, B.; Cuatrecasas, M.; Pineda, E.; Torne, A.; Crespo, G.; Martin-Algarra, S.; Perez-Ruiz, E.; Reig, O.; Viladot, M.; Font, C.; Adamo, B.; Vidal, M.; Gaba, L ANNALS OF ONCOLOGY 0923-7534 (2018) DOI / 10.1093/annonc/mdy335 Bronze

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Article Combined PD-1, BRAF and MEK inhibition in advanced BRAF-mutant melanoma: safety run-in and biomarker cohorts of COMBI-i Dummer, Reinhard; Lebbe, Celeste; Atkinson, Victoria; Mandala, Mario; Nathan, Paul D.; Arance, Ana; Richtig, Erika; Yamazaki, Naoya; Robert, Caroline; Schadendorf, Dirk; Tawbi, Hussein A.; Ascierto, Paolo A.; Ribas, Antoni; Flaherty, Keith T.; Pakhle, Neha NATURE MEDICINE 1078-8956 (2020) DOI / 10.1038/s41591-020-1082-2

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Article Real-world treatment patterns and outcomes among metastatic cutaneous melanoma patients treated with ipilimumab Mohr, P.; Ascierto, P.; Arance, A.; McArthur, G.; Hernaez, A.; Kaskel, P.; Shinde, R.; Stevinson, K. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY 0926-9959 (2018) DOI / 10.1111/jdv.14633

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Article Preliminary safety and efficacy of first-line pertuzumab combined with trastuzumab and taxane therapy for HER2-positive locally recurrent or metastatic breast cancer (PERUSE) Bachelot, T.; Ciruelos, E.; Schneeweiss, A.; Puglisi, F.; Peretz-Yablonski, T.; Bondarenko, I.; Paluch-Shimon, S.; Wardley, A.; Merot, J. -l.; du Toit, Y.; Easton, V.; Lindegger, N.; Miles, D.; Bouzid, Kamel; Campone, Mario; Coudert, Bruno; Nowecki, Zbigni ANNALS OF ONCOLOGY 0923-7534 (2019) DOI / 10.1093/annonc/mdz061 Bronze

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Article Pembrolizumab for locally advanced and recurrent/metastatic cutaneous squamous cell carcinoma (KEYNOTE-629 study): an open-label, nonrandomized, multicenter, phase II trial Hughes, B. G. M.; Munoz-Couselo, E.; Mortier, L.; Bratland, A.; Gutzmer, R.; Roshdy, O.; Mendoza, R. Gonzalez; Schachter, J.; Arance, A.; Grange, F.; Meyer, N.; Joshi, A.; Billan, S.; Zhang, P.; Gumuscu, B.; Swaby, R. F.; Grob, J. -J. ANNALS OF ONCOLOGY 0923-7534 (2021) DOI / 10.1016/j.annonc.2021.07.008 Hybrid

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Article Phase I Dose-Escalation and -Expansion Study of the BRAF Inhibitor Encorafenib (LGX818) in Metastatic BRAF-Mutant Melanoma Delord, Jean-Pierre; Robert, Caroline; Nyakas, Marta; McArthur, Grant A.; Kudchakar, Ragini; Mahipal, Amit; Yamada, Yasuhide; Sullivan, Ryan; Arance, Ana; Kefford, Richard F.; Carlino, Matteo S.; Hidalgo, Manuel; Gomez-Roca, Carlos; Michel, Daniela; Serout CLINICAL CANCER RESEARCH 1078-0432 (2017) DOI / 10.1158/1078-0432.ccr-16-2923 Green accepted, Bronze

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Article Quality of life in patients with BRAF-mutant melanoma receiving the combination encorafenib plus binimetinib: Results from a multicentre, open-label, randomised, phase III study (COLUMBUS) Gogas, Helen; Dummer, Reinhard; Ascierto, Paolo A.; Arance, Ana; Mandala, Mario; Liszkay, Gabriella; Garbe, Claus; Schadendorf, Dirk; Krajsova, Ivana; Gutzmer, Ralf; Sileni, Vanna Chiarion; Dutriaux, Caroline; Yamazaki, Naoya; Loquai, Carmen; Queirolo, Pao EUROPEAN JOURNAL OF CANCER 0959-8049 (2021) DOI / 10.1016/j.ejca.2021.04.028

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Article Update on tolerability and overall survival in COLUMBUS: landmark analysis of a randomised phase 3 trial of encorafenib plus binimetinib vs vemurafenib or encorafenib in patients with BRAF V600-mutant melanoma Ascierto, Paolo A.; Dummer, Reinhard; Gogas, Helen J.; Flaherty, Keith T.; Arance, Ana; Mandala, Mario; Liszkay, Gabriella; Garbe, Claus; Schadendorf, Dirk; Krajsova, Ivana; Gutzmer, Ralf; de Groot, Jan Willem B.; Loquai, Carmen; Gollerkeri, Ashwin; Pickar EUROPEAN JOURNAL OF CANCER 0959-8049 (2020) DOI / 10.1016/j.ejca.2019.11.016 Gold other, Green accepted

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Article Long-term outcomes in patients with advanced melanoma who had initial stable disease with pembrolizumab in KEYNOTE-001 and KEYNOTE-006 Hamid, Omid; Robert, Caroline; Daud, Adil; Carlino, Matteo S.; Mitchell, Tara C.; Hersey, Peter; Schachter, Jacob; V. Long, Georgina; Hodi, F. Stephen; Wolchok, Jedd D.; Arance, Ana; Grob, Jean Jacques; Joshua, Anthony M.; Weber, Jeffrey S.; Mortier, Laure EUROPEAN JOURNAL OF CANCER 0959-8049 (2021) DOI / 10.1016/j.ejca.2021.08.013 Hybrid

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Article Antitumour activity of pembrolizumab in advanced mucosal melanoma: a post-hoc analysis of KEYNOTE-001, 002, 006 Hamid, Omid; Robert, Caroline; Ribas, Antoni; Hodi, F. Stephen; Walpole, Euan; Daud, Adil; Arance, Ana S.; Brown, Ewan; Hoeller, Christoph; Mortier, Laurent; Schachter, Jacob; Long, Jianmin; Ebbinghaus, Scot; Ibrahim, Nageatte; Butler, Marcus BRITISH JOURNAL OF CANCER 0007-0920 (2018) DOI / 10.1038/s41416-018-0207-6 Gold other, Green published

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Article Intermittent BRAF inhibition in advanced BRAF mutated melanoma results of a phase II randomized trial Gonzalez-Cao, Maria; Mayo Casas, Clara; Oramas, Juana; Berciano-Guerrero, Miguel A.; de la Cruz, Luis; Cerezuela, Pablo; Arance, Ana; Munoz-Couselo, Eva; Espinosa, Enrique; Puertolas, Teresa; Diaz Beveridge, Roberto; Ochenduszko, Sebastian; Villanueva, Mar NATURE COMMUNICATIONS (2021) DOI / 10.1038/s41467-021-26572-6 Gold

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Letter Vasculitic neuropathy induced by pembrolizumab Aya, F.; Ruiz-Esquide, V.; Viladot, M.; Font, C.; Prieto-Gonzalez, S.; Prat, A.; Arance, A. ANNALS OF ONCOLOGY 0923-7534 (2017) DOI / 10.1093/annonc/mdw613 Bronze

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Article Rechallenge with BRAF-directed treatment in metastatic melanoma: A multi-institutional retrospective study Valpione, Sara; Carlino, Matteo S.; Mangana, Johanna; Mooradian, Meghan J.; McArthur, Grant; Schadendorf, Dirk; Hauschild, Axel; Menzies, Alexander M.; Arance, Ana; Ascierto, Paolo A.; Di Giacomo, AnnaMaria; De Rosa, Francesco; Larkin, James; Park, John J. EUROPEAN JOURNAL OF CANCER 0959-8049 (2018) DOI / 10.1016/j.ejca.2017.12.007 Gold other, Green published

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Article An open-label, multicentre safety study of vemurafenib in patients with BRAF(V600)-mutant metastatic melanoma: final analysis and a validated prognostic scoring system Larkin, James; Brown, Michael P.; Arance, Ana M.; Hauschild, Axel; Queirolo, Paola; Del Vecchio, Michele; Ascierto, Paolo A.; Krajsova, Ivana; Schachter, Jacob; Neyns, Bart; Garbe, Claus; Sileni, Vanna Chiarion; Mandala, Mario; Gogas, Helen; Espinosa, Enri EUROPEAN JOURNAL OF CANCER 0959-8049 (2019) DOI / 10.1016/j.ejca.2018.11.018

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Article Vemurafenib in metastatic melanoma patients with brain metastases: an open-label, single-arm, phase 2, multicentre study McArthur, G. A.; Maio, M.; Arance, A.; Nathan, P.; Blank, C.; Avril, M. -F.; Garbe, C.; Hauschild, A.; Schadendorf, D.; Hamid, O.; Fluck, M.; Thebeau, M.; Schachter, J.; Kefford, R.; Chamberlain, M.; Makrutzki, M.; Robson, S.; Gonzalez, R.; Margolin, K. ANNALS OF ONCOLOGY 0923-7534 (2017) DOI / 10.1093/annonc/mdw641 Green published, Bronze

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Article Genomic analysis and clinical management of adolescent cutaneous melanoma Rabbie, Roy; Rashid, Mamunur; Arance, Ana M.; Sanchez, Marcelo; Tell-Marti, Gemma; Potrony, Miriam; Conill, Carles; van Doorn, Remco; Dentro, Stefan; Gruis, Nelleke A.; Corrie, Pippa; Iyer, Vivek; Daniela Robles-Espinoza, Carla; Puig-Butille, Joan A.; Puig PIGMENT CELL & MELANOMA RESEARCH 1755-1471 (2017) DOI / 10.1111/pcmr.12574 Green published, Gold other

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Article Health Care Resource Utilization and Associated Costs Among Metastatic Cutaneous Melanoma Patients Treated with Ipilimumab (INTUITION Study) McArthur, Grant A.; Mohr, Peter; Ascierto, Paolo Antonio; Arance, Ana; Hernaez, Ana Banos; Kaskel, Peter; Weichenthal, Michael; Shinde, Reshma; Stevinson, Kendall ONCOLOGIST 1083-7159 (2017) DOI / 10.1634/theoncologist.2016-0272 Green published, Gold other

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Article Adjuvant nivolumab for stage III/IV melanoma: evaluation of safety outcomes and association with recurrence-free survival Mandala, Mario; Larkin, James; Ascierto, Paolo Antonio; Del Vecchio, Michele; Gogas, Helen; Cowey, C. Lance; Arance, Ana; Dalle, Stephane; Schenker, Michael; Grob, Jean-Jacques; Chiarion-Sileni, Vanna; Marquez, Ivan; Butler, Marcus O.; Di Giacomo, Anna Mar JOURNAL FOR IMMUNOTHERAPY OF CANCER (2021) DOI / 10.1136/jitc-2021-003188 Green published, Gold