Pharmacology & Toxicology


  Listando 23 trabajos del autor/autora 38
Lista de trabajos en el área Pharmacology & Toxicology
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Article Tetrahydrocannabinolic acid is a potent PPAR gamma agonist with neuroprotective activity Nadal, Xavier; del Rio, Carmen; Casano, Salvatore; Palomares, Belen; Ferreiro-Vera, Carlos; Navarrete, Carmen; Sanchez-Carnerero, Carolina; Cantarero, Irene; Bellido, Maria Luz; Meyer, Stefan; Morello, Gaetano; Appendino, Giovanni; Munoz, Eduardo BRITISH JOURNAL OF PHARMACOLOGY 0007-1188 (2017) DOI / 10.1111/bph.14019 Green published, Bronze
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Article Tetrahydrocannabinolic acid A (THCA-A) reduces adiposity and prevents metabolic disease caused by diet-induced obesity Palomares, Belen; Ruiz-Pino, Francisco; Garrido-Rodriguez, Martin; Eugenia Prados, M.; Sanchez-Garrido, Miguel A.; Velasco, Inmaculada; Vazquez, Maria J.; Nadal, Xavier; Ferreiro-Vera, Carlos; Morrugares, Rosario; Appendino, Giovanni; Calzado, Marco A.; Te BIOCHEMICAL PHARMACOLOGY 0006-2952 (2020) DOI / 10.1016/j.bcp.2019.113693 Green submitted
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Article Delta(9)-Tetrahydrocannabinolic acid alleviates collagen-induced arthritis: Role of PPAR gamma and CB(1)receptors Palomares, Belen; Garrido-Rodriguez, Martin; Gonzalo-Consuegra, Claudia; Gomez-Canas, Maria; Saen-oon, Suwipa; Soliva, Robert; Collado, Juan A.; Fernandez-Ruiz, Javier; Morello, Gaetano; Calzado, Marco A.; Appendino, Giovanni; Munoz, Eduardo BRITISH JOURNAL OF PHARMACOLOGY 0007-1188 (2020) DOI / 10.1111/bph.15155
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Article Delta 9-Tetrahydrocannabinolic Acid markedly alleviates liver fibrosis and inflammation in mice Carmona-Hidalgo, Beatriz; Gonzalez-Mariscal, Isabel; Garcia-Martin, Adela; Prados, Maria E.; Ruiz-Pino, Francisco; Appendino, Giovanni; Tena-Sempere, Manuel; Munoz, Eduardo PHYTOMEDICINE 0944-7113 (2021) DOI / 10.1016/j.phymed.2020.153426
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Article Cannabinoid derivatives acting as dual PPAR gamma/CB2 agonists as therapeutic agents for systemic sclerosis Garcia-Martin, Adela; Garrido-Rodriguez, Martin; Navarrete, Carmen; Caprioglio, Diego; Palomares, Belen; DeMesa, Jim; Rollland, Alain; Appendino, Giovanni; Munoz, Eduardo BIOCHEMICAL PHARMACOLOGY 0006-2952 (2019) DOI / 10.1016/j.bcp.2019.02.029
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Review The endocannabinoid system of the skin. A potential approach for the treatment of skin disorders del Rio, Carmen; Millan, Estrella; Garcia, Victor; Appendino, Giovanni; DeMesa, Jim; Munoz, Eduardo BIOCHEMICAL PHARMACOLOGY 0006-2952 (2018) DOI / 10.1016/j.bcp.2018.08.022
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Article Neuroprotective effects of the cannabigerol quinone derivative VCE-003.2 in SOD1(G93A) transgenic mice, an experimental model of amyotrophic lateral sclerosis Rodriguez-Cueto, Carmen; Santos-Garcia, Irene; Garcia-Toscano, Laura; Espejo-Porras, Francisco; Bellido, MLuz; Fernandez-Ruiz, Javier; Munoz, Eduardo; de Lago, Eva BIOCHEMICAL PHARMACOLOGY 0006-2952 (2018) DOI / 10.1016/j.bcp.2018.07.049
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Article Structure-Effect Relationships of Novel Semi-Synthetic Cannabinoid Derivatives Goetz, Marcus R.; Collado, Juan A.; Fernandez-Ruiz, Javier; Fiebich, Bernd L.; Garcia-Toscano, Laura; Gomez-Canas, Maria; Koch, Oskar; Leha, Andreas; Munoz, Eduardo; Navarrete, Carmen; Pazos, Maria R.; Holzgrabe, Ulrike FRONTIERS IN PHARMACOLOGY (2019) DOI / 10.3389/fphar.2019.01284 Gold DOAJ, Green published
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Article VCE-004.3, a cannabidiol aminoquinone derivative, prevents bleomycin-induced skin fibrosis and inflammation through PPAR gamma- and CB2 receptor-dependent pathways del Rio, Carmen; Cantarero, Irene; Palomares, Belen; Gomez-Canas, Maria; Fernandez-Ruiz, Javier; Pavicic, Carolina; Garcia-Martin, Adela; Luz Bellido, Maria; Ortega-Castro, Rafaela; Perez-Sanchez, Carlos; Lopez-Pedrera, Chary; Appendino, Giovanni; Calzado, BRITISH JOURNAL OF PHARMACOLOGY 0007-1188 (2018) DOI / 10.1111/bph.14450 Green published, Bronze
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Article EHP-101, an oral formulation of the cannabidiol aminoquinone VCE-004.8, alleviates bleomycin-induced skin and lung fibrosis Garcia-Martin, Adela; Garrido-Rodriguez, Martin; Navarrete, Carmen; del Rio, Carmen; Bellido, Maria L.; Appendino, Giovanni; Calzado, Marco A.; Munoz, Eduardo BIOCHEMICAL PHARMACOLOGY 0006-2952 (2018) DOI / 10.1016/j.bcp.2018.07.047
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Article The Oxidation of Phytocannabinoids to Cannabinoquinoids Caprioglio, Diego; Mattoteia, Daiana; Pollastro, Federica; Negri, Roberto; Lopatriello, Annalisa; Chianese, Giuseppina; Minassi, Alberto; Collado, Juan A.; Munoz, Eduardo; Taglialatela-Scafati, Orazio; Appendino, Giovanni JOURNAL OF NATURAL PRODUCTS 0163-3864 (2020) DOI / 10.1021/acs.jnatprod.9b01284
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Article The dimerization of Delta(9)-tetrahydrocannabinolic acid A (THCA-A) Cuadari, Arben; Pollastro, Federica; Unciti-Broceta, Juan D.; Caprioglio, Diego; Minassi, Alberto; Lopatriello, Annalisa; Munoz, Eduardo; Taglialatela-Scafati, Orazio; Appendino, Giovanni ACTA PHARMACEUTICA SINICA B 2211-3835 (2019) DOI / 10.1016/j.apsb.2019.06.007 Gold DOAJ, Green published
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Article (+)-trans-Cannabidiol-2-hydroxy pentyl is a dual CB1R antagonist/CB2R agonist that prevents diabetic nephropathy in mice Gonzalez-Mariscal, Isabel; Carmona-Hidalgo, Beatriz; Winkler, Matthias; Unciti-Broceta, Juan D.; Escamilla, Alejandro; Gomez-Canas, Maria; Fernandez-Ruiz, Javier; Fiebich, Bernd L.; Romero-Zerbo, Silvana-Yanina; Bermudez-Silva, Francisco J.; Collado, Juan PHARMACOLOGICAL RESEARCH 1043-6618 (2021) DOI / 10.1016/j.phrs.2021.105492
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Article O -Methyl Phytocannabinoids: Semi-synthesis, Analysis in Cannabis Flowerheads, and Biological Activity * Caprioglio, Diego; Allegrone, Gianna; Pollastro, Federica; Valera, Stefano; Lopatriello, Annalisa; Collado, Juan A.; Munoz, Eduardo; Appendino, Giovanni; Taglialatela-Scafati, Orazio PLANTA MEDICA 0032-0943 (2019) DOI / 10.1055/a-0883-5383
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Article "Photo-Rimonabant": Synthesis and Biological Evaluation of Novel Photoswitchable Molecules Derived from Rimonabant Lead to a Highly Selective and Nanomolar "Cis-On" CB1R Antagonist Rodriguez-Soacha, Diego A.; Fender, Julia; Ramirez, Yesid A.; Antonio Collado, Juan; Munoz, Eduardo; Maitra, Rangan; Sotriffer, Christoph; Lorenz, Kristina; Decker, Michael ACS CHEMICAL NEUROSCIENCE 1948-7193 (2021) DOI / 10.1021/acschemneuro.1c00086
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Article Triterpenoid Hydroxamates as HIF Prolyl Hydrolase Inhibitors Minassi, Alberto; Rogati, Federica; Cruz, Cristina; Eugenia Prados, M.; Galera, Nuria; Jinenez, Carla; Appendino, Giovanni; Luz Bellido, M.; Calzado, Marco A.; Caprioglio, Diego; Munoz, Eduardo JOURNAL OF NATURAL PRODUCTS 0163-3864 (2018) DOI / 10.1021/acs.jnatprod.8b00514
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Article Anti-Inflammatory and Anti-Oxidative Effects of AM404 in IL-1 beta-Stimulated SK-N-SH Neuroblastoma Cells Apweiler, Matthias; Streyczek, Jana; Saliba, Soraya Wilke; Ditrich, Johannes; Munoz, Eduardo; Fiebich, Bernd L. FRONTIERS IN PHARMACOLOGY (2021) DOI / 10.3389/fphar.2021.789074 Gold
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Article Identification of a Strigoterpenoid with Dual Nrf2 and Nf-kappa B Modulatory Activity Rogati, Federica; Milan, Estrella; Appendino, Giovanni; Correa, Alejandro; Caprioglio, Diego; Minassi, Alberto; Munoz, Eduardo ACS MEDICINAL CHEMISTRY LETTERS 1948-5875 (2019) DOI / 10.1021/acsmedchemlett.8b00604 Green published
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Article Betulinic Acid Hydroxamate is Neuroprotective and Induces Protein Phosphatase 2A-Dependent HIF-1 alpha Stabilization and Post-transcriptional Dephosphorylation of Prolyl Hydrolase 2 Prados, Maria E.; Correa-Saez, Alejandro; Unciti-Broceta, Juan D.; Garrido-Rodriguez, Martin; Jimenez-Jimenez, Carla; Mazzone, Massimiliano; Minassi, Alberto; Appendino, Giovanni; Calzado, Marco A.; Munoz, Eduardo NEUROTHERAPEUTICS 1933-7213 (2021) DOI / 10.1007/s13311-021-01089-4 Green published, Hybrid
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Article Betulinic acid hydroxamate prevents colonic inflammation and fibrosis in murine models of inflammatory bowel disease Prados, Maria E.; Garcia-Martin, Adela; Unciti-Broceta, Juan D.; Palomares, Belen; Collado, Juan A.; Minassi, Alberto; Calzado, Marco A.; Appendino, Giovanni; Munoz, Eduardo ACTA PHARMACOLOGICA SINICA 1671-4083 (2020) DOI / 10.1038/s41401-020-0497-0
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Article EHP-101 alleviates angiotensin II-induced fibrosis and inflammation in mice Garcia-Martin, Adela; Navarrete, Carmen; Garrido-Rodriguez, Martin; Prados, Maria E.; Caprioglio, Diego; Appendino, Giovanni; Munoz, Eduardo BIOMEDICINE & PHARMACOTHERAPY 0753-3322 (2021) DOI / 10.1016/j.biopha.2021.112007 Green published, Gold
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Article Agathadiol, a labdane diterpenoid from juniper berries, is a positive allosteric modulator of CB1R Salamone, Stefano; Appendino, Giovanni; Khalili, Adil; Pollastro, Federica; Munoz, Eduardo; Unciti-Broceta, Juan D. FITOTERAPIA 0367-326X (2021) DOI / 10.1016/j.fitote.2021.105059
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Article Anti-inflammatory sesquiterpene lactones from Onopordum illyricum L. (Asteraceae), an Italian medicinal plant Formisano, Carmen; Sanna, Cinzia; Ballero, Mauro; Chianese, Giuseppina; Sirignano, Carmina; Rigano, Daniela; Millan, Estrella; Munoz, Eduardo; Taglialatela-Scafati, Orazio FITOTERAPIA 0367-326X (2017) DOI / 10.1016/j.fitote.2016.11.006

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