Chemistry
Listando 14 trabajos del autor/autora 38
Lista de trabajos en el área Chemistry
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Article
Water Sculpts the Distinctive Shapes and Dynamics of the Tumor-Associated Carbohydrate Tn Antigens: Implications for Their Molecular Recognition
Bermejo, Iris A.; Usabiaga, Imanol; Companon, Ismael; Castro-Lopez, Jorge; Insausti, Aran; Fernandez, Jose A.; Avenoza, Alberto; Busto, Jesus H.; Jimenez-Barbero, Jesus; Asensio, Juan L.; Peregrina, Jesus M.; Jimenez-Oses, Gonzalo; Hurtado-Guerrero, Ramon;
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
0002-7863 (2018)
DOI /
10.1021/jacs.8b04801
Green submitted, Hybrid
Mentions
63
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4
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Article
Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage
Companon, Ismael; Guerreiro, Ana; Mangini, Vincenzo; Castro-Lopez, Jorge; Escudero-Casao, Margarita; Avenoza, Alberto; Busto, Jesus H.; Castillon, Sergio; Jimenez-Barbero, Jesus; Asensio, Juan L.; Jimenez-Oses, Gonzalo; Boutureira, Omar; Peregrina, Jesus M
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
0002-7863 (2019)
DOI /
10.1021/jacs.8b13503
Green accepted, Green submitted
Mentions
40
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3
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Article
Synthesis, conformational analysis and in vivo assays of an anti-cancer vaccine that features an unnatural antigen based on an sp(2)-iminosugar fragment
Bermejo, Iris A.; Navo, Claudio D.; Castro-Lopez, Jorge; Guerreiro, Ana; Jimenez-Moreno, Ester; Fernandez, Elena M. Sanchez; Garcia-Martin, Fayna; Hinou, Hiroshi; Nishimura, Shin-Ichiro; Fernandez, Jose M. Garcia; Mellet, Carmen Ortiz; Avenoza, Alberto; Bu
CHEMICAL SCIENCE
2041-6520 (2020)
DOI /
10.1039/c9sc06334j
Green published, Gold
Mentions
80
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Article
The Use of Fluoroproline in MUC1 Antigen Enables Efficient Detection of Antibodies in Patients with Prostate Cancer
Somovilla, Victor J.; Bermejo, Iris A.; Albuquerque, Ines S.; Martinez-Saez, Nuria; Castro-Lopez, Jorge; Garcia-Martin, Fayna; Companon, Ismael; Hinou, Hiroshi; Nishimura, Shin-Ichiro; Jimenez-Barbero, Jesus; Asensio, Juan L.; Avenoza, Alberto; Busto, Jesu
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
0002-7863 (2017)
DOI /
10.1021/jacs.7b09447
Green published, Hybrid
Mentions
42
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Structural characterization of an unprecedented lectin-like antitumoral anti-MUC1 antibody
Macias-Leon, Javier; Bermejo, Iris A.; Asin, Alicia; Garcia-Garcia, Ana; Companon, Ismael; Jimenez-Moreno, Ester; Coelho, Helena; Mangini, Vincenzo; Albuquerque, Ines S.; Marcelo, Filipa; Asensio, Juan L.; Bernardes, Goncalo J. L.; Joshi, Hiren J.; Fiammen
CHEMICAL COMMUNICATIONS
1359-7345 (2020)
DOI /
10.1039/d0cc06349e
Mentions
37
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0
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Article
FUT8-Directed Core Fucosylation of N-glycans Is Regulated by the Glycan Structure and Protein Environment
Garcia-Garcia, Ana; Serna, Sonia; Yang, Zhang; Delso, Ignacio; Taleb, Victor; Hicks, Thomas; Artschwager, Raik; Vakhrushev, Sergey Y.; Clausen, Henrik; Angulo, Jesus; Corzana, Francisco; Reichardt, Niels C.; Hurtado-Guerrero, Ramon
ACS CATALYSIS
2155-5435 (2021)
DOI /
10.1021/acscatal.1c01698
Mentions
16
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1
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NleB/SseK-catalyzed arginine-glycosylation and enteropathogen virulence are finely tuned by a single variable position contiguous to the catalytic machinery
Garcia-Garcia, Ana; Hicks, Thomas; El Qaidi, Samir; Zhu, Congrui; Hardwidge, Philip R.; Angulo, Jesus; Hurtado-Guerrero, Ramon
CHEMICAL SCIENCE
2041-6520 (2021)
DOI /
10.1039/d1sc04065k
Gold
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37
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Asparagine Tautomerization in Glycosyltransferase Catalysis. The Molecular Mechanism of Protein O-Fucosyltransferase 1
Piniello, Beatriz; Lira-Navarrete, Erandi; Takeuchi, Hideyuki; Takeuchi, Megumi; Haltiwanger, Robert S.; Hurtado-Guerrero, Ramon; Rovira, Carme
ACS CATALYSIS
2155-5435 (2021)
DOI /
10.1021/acscatal.1c01785
Mentions
4
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0
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1
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Article
Structural Analysis of a GalNAc-T2 Mutant Reveals an Induced-Fit Catalytic Mechanism for GalNAc-Ts
de las Rivas, Matilde; Coelho, Helena; Diniz, Ana; Lira-Navarrete, Erandi; Companon, Ismael; Jimenez-Barbero, Jesus; Schjoldager, Katrine T.; Bennett, Eric P.; Vakhrushev, Sergey Y.; Clausen, Henrik; Corzana, Francisco; Marcelo, Filipa; Hurtado-Guerrero, R
CHEMISTRY-A EUROPEAN JOURNAL
0947-6539 (2018)
DOI /
10.1002/chem.201800701
Green accepted
Mentions
17
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Article
Protein O-Fucosyltransferase 1 Undergoes Interdomain Flexibility in Solution
Lira-Navarrete, Erandi; Pallares, Maria Carmen; Castello, Fabio; Ruedas-Rama, Maria J.; Orte, Angel; Lostao, Anabel; Hurtado-Guerrero, Ramon
MOLECULES
(2021)
DOI /
10.3390/molecules26082105
Gold DOAJ, Green published
Mentions
16
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Article
Structural and Mechanistic Insights into the Catalytic-Domain-Mediated Short-Range Glycosylation Preferences of GalNAc-T4
de las Rivas, Matilde; Daniel, Earnest James Paul; Coelho, Helena; Lira-Navarrete, Erandi; Raich, Lluis; Companon, Ismael; Diniz, Ana; Lagartera, Laura; Jimenez-Barbero, Jesus; Clausen, Henrik; Rovira, Carme; Marcelo, Filipa; Corzana, Francisco; Gerken, Th
ACS CENTRAL SCIENCE
2374-7943 (2018)
DOI /
10.1021/acscentsci.8b00488
Gold DOAJ, Green published
Mentions
18
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0
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0
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Article
Fucosyltransferase-specific inhibition via next generation of fucose mimetics
Martin, Kyle C.; Tricomi, Jacopo; Corzana, Francisco; Garcia-Garcia, Ana; Ceballos-Laita, Laura; Hicks, Thomas; Monaco, Serena; Angulo, Jesus; Hurtado-Guerrero, Ramon; Richichi, Barbara; Sackstein, Robert
CHEMICAL COMMUNICATIONS
1359-7345 (2021)
DOI /
10.1039/d0cc04847j
Mentions
8
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0
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0
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Review
A perspective on structural and mechanistic aspects of protein O-fucosylation
Lira-Navarrete, Erandi; Hurtado-Guerrero, Ramon
ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS
2053-230X (2018)
DOI /
10.1107/s2053230x18004788
Green published, Gold other
Mentions
1
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0
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Article
Production of a Granulysin-Based, Tn-Targeted Cytolytic Immunotoxin Using Pulsed Electric Field Technology
Guerrero-Ochoa, Patricia; Aguilar-Machado, Diederich; Ibanez-Perez, Raquel; Macias-Leon, Javier; Hurtado-Guerrero, Ramon; Raso, Javier; Anel, Alberto
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
1661-6596 (2020)
DOI /
10.3390/ijms21176165
Gold DOAJ, Green published
