Trabajos de Salvador Ventura

Biology & Biochemistry


  Listando 48 trabajos del autor/autora 38
Lista de trabajos en el área Biology & Biochemistry
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Article alpha-Helical peptidic scaffolds to target alpha-synuclein toxic species with nanomolar affinity Santos, Jaime; Gracia, Pablo; Navarro, Susanna; Pena-Diaz, Samuel; Pujols, Jordi; Cremades, Nunilo; Pallares, Irantzu; Ventura, Salvador NATURE COMMUNICATIONS (2021) DOI / 10.1038/s41467-021-24039-2 Gold, Green published
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Article Small molecule inhibits alpha-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons Pujols, Jordi; Pena-Diaz, Samuel; Lazaro, Diana F.; Peccati, Francesca; Pinheiro, Francisca; Gonzalez, Danilo; Carija, Anita; Navarro, Susanna; Conde-Gimenez, Maria; Garcia, Jesus; Guardiola, Salvador; Giralt, Ernest; Salvatella, Xavier; Sancho, Javier; So PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 0027-8424 (2018) DOI / 10.1073/pnas.1804198115 Green published, Bronze
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Article DisProt: intrinsic protein disorder annotation in 2020 Hatos, Andras; Hajdu-Soltesz, Borbala; Monzon, Alexander M.; Palopoli, Nicolas; Alvarez, Lucia; Aykac-Fas, Burcu; Bassot, Claudio; Benitez, Guillermo, I; Bevilacqua, Martina; Chasapi, Anastasia; Chemes, Lucia; Davey, Norman E.; Davidovic, Radoslav; Dunker, NUCLEIC ACIDS RESEARCH 0305-1048 (2020) DOI / 10.1093/nar/gkz975 Gold DOAJ, Green published, Green accepted
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Article Aggrescan3D (A3D) 2.0: prediction and engineering of protein solubility Kuriata, Aleksander; Iglesias, Valentin; Pujols, Jordi; Kurcinski, Mateusz; Kmiecik, Sebastian; Ventura, Salvador NUCLEIC ACIDS RESEARCH 0305-1048 (2019) DOI / 10.1093/nar/gkz321 Green submitted, Gold, Green published
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Article Aggrescan3D standalone package for structure-based prediction of protein aggregation properties Kuriata, Aleksander; Iglesias, Valentin; Kurcinski, Mateusz; Ventura, Salvador; Kmiecik, Sebastian BIOINFORMATICS 1367-4803 (2019) DOI / 10.1093/bioinformatics/btz143
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Article High-Throughput Screening Methodology to Identify Alpha-Synuclein Aggregation Inhibitors Pujols, Jordi; Pena-Diaz, Samuel; Conde-Gimenez, Maria; Pinheiro, Francisca; Navarro, Susanna; Sancho, Javier; Ventura, Salvador INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 1661-6596 (2017) DOI / 10.3390/ijms18030478 Gold, Green submitted, Green published
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Review Prion-like proteins: from computational approaches to proteome-wide analysis Gil-Garcia, Marcos; Iglesias, Valentin; Pallares, Irantzu; Ventura, Salvador FEBS OPEN BIO 2211-5463 (2021) DOI / 10.1002/2211-5463.13213 Green accepted, Gold
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Article Perfecting prediction of mutational impact on the aggregation propensity of the ALS-associated hnRNPA2 prion-like protein Batlle, Cristina; Rosario Fernandez, Maria; Iglesias, Valentin; Ventura, Salvador FEBS LETTERS 0014-5793 (2017) DOI / 10.1002/1873-3468.12698 Bronze
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Article SGnn: A Web Server for the Prediction of Prion-Like Domains Recruitment to Stress Granules Upon Heat Stress Iglesias, Valentin; Santos, Jaime; Santos-Suarez, Juan; Pintado-Grima, Carlos; Ventura, Salvador FRONTIERS IN MOLECULAR BIOSCIENCES (2021) DOI / 10.3389/fmolb.2021.718301 Gold, Green published
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Article In silico Characterization of Human Prion-Like Proteins: Beyond Neurological Diseases Iglesias, Valentin; Paladin, Lisanna; Juan-Blanco, Teresa; Pallares, Irantzu; Aloy, Patrick; Tosatto, Silvio C. E.; Ventura, Salvador FRONTIERS IN PHYSIOLOGY (2019) DOI / 10.3389/fphys.2019.00314 Gold, Green published
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Review Chemical Chaperones as Novel Drugs for Parkinson's Disease Pujols, Jordi; Pena-Diaz, Samuel; Pallares, Irantzu; Ventura, Salvador TRENDS IN MOLECULAR MEDICINE 1471-4914 (2020) DOI / 10.1016/j.molmed.2020.01.005
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Article Rational design of small molecules able to inhibit alpha-synuclein amyloid aggregation for the treatment of Parkinson's disease Vittorio, Serena; Adornato, Ilenia; Gitto, Rosaria; Pena-Diaz, Samuel; Ventura, Salvador; De Luca, Laura JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 1475-6366 (2020) DOI / 10.1080/14756366.2020.1816999 Gold DOAJ, Green published
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Article Biasing the native alpha-synuclein conformational ensemble towards compact states abolishes aggregation and neurotoxicity Carija, Anita; Pinheiro, Francisca; Pujols, Jordi; Bras, Ines C.; Lazaro, Diana Fernandes; Santambrogio, Carlo; Grandori, Rita; Outeiro, Tiago F.; Navarro, Susanna; Ventura, Salvador REDOX BIOLOGY 2213-2317 (2019) DOI / 10.1016/j.redox.2019.101135 Gold, Green published
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Article Protein aggregation into insoluble deposits protects from oxidative stress Carija, Anita; Navarro, Susanna; Sanchez de Groot, Natalia; Ventura, Salvador REDOX BIOLOGY 2213-2317 (2017) DOI / 10.1016/j.redox.2017.03.027 Green published, Gold
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Article Amyloidogenicity as a driving force for the formation of functional oligomers Azizyan, Rafayel A.; Wang, Weiqiang; Anikeenko, Alexey; Radkova, Zinaida; Bakulina, Anastasia; Garro, Adriana; Charlier, Landry; Dumas, Christian; Ventura, Salvador; Kajava, Andrey, V JOURNAL OF STRUCTURAL BIOLOGY 1047-8477 (2020) DOI / 10.1016/j.jsb.2020.107604
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Review Decoding the role of coiled-coil motifs in human prion-like proteins Behbahanipour, Molood; Garcia-Pardo, Javier; Ventura, Salvador PRION 1933-6896 (2021) DOI / 10.1080/19336896.2021.1961569 Green published, Gold
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Article The fitness cost and benefit of phase-separated protein deposits de Groot, Natalia Sanchez; Burgas, Marc Torrent; Ravarani, Charles N. J.; Trusina, Ala; Ventura, Salvador; Babu, M. Madan MOLECULAR SYSTEMS BIOLOGY 1744-4292 (2019) DOI / 10.15252/msb.20178075 Green published, Green submitted, Gold
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Article C-mannosylation supports folding and enhances stability of thrombospondin repeats Shcherbakova, Aleksandra; Preller, Matthias; Taft, Manuel H.; Pujols, Jordi; Ventura, Salvador; Tiemann, Birgit; Buettner, Falk F. R.; Bakker, Hans ELIFE 2050-084X (2019) DOI / 10.7554/elife.52978 Gold DOAJ, Green published
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Review AlphaFold and the amyloid landscape Pinheiro, Francisca; Santos, Jaime; Ventura, Salvador JOURNAL OF MOLECULAR BIOLOGY 0022-2836 (2021) DOI / 10.1016/j.jmb.2021.167059 Bronze
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Article Evaluation of the Impact of Protein Aggregation on Cellular Oxidative Stress in Yeast Carija, Anita; Ventura, Salvador; Navarro, Susanna JOVE-JOURNAL OF VISUALIZED EXPERIMENTS 1940-087X (2018) DOI / 10.3791/57470 Green published
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Article Global Protein Stabilization Does Not Suffice to Prevent Amyloid Fibril Formation Marinelli, Patrizia; Navarro, Susanna; Bano-Polo, Manuel; Morel, Bertrand; Grana-Montes, Ricardo; Sabe, Anna; Canals, Francesc; Rosario Fernandez, Maria; Conejero-Lara, Francisco; Ventura, Salvador ACS CHEMICAL BIOLOGY 1554-8929 (2018) DOI / 10.1021/acschembio.8b00607
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Article Characterization of Soft Amyloid Cores in Human Prion-Like Proteins Batlle, Cristina; Sanchez de Groot, Natalia; Iglesias, Valentin; Navarro, Susanna; Ventura, Salvador SCIENTIFIC REPORTS 2045-2322 (2017) DOI / 10.1038/s41598-017-09714-z Green published, Gold
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Editorial Material The Transcription Terminator Rho: A First Bacterial Prion Pallares, Irantzu; Ventura, Salvador TRENDS IN MICROBIOLOGY 0966-842X (2017) DOI / 10.1016/j.tim.2017.03.008
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Article AMYCO: evaluation of mutational impact on prion-like proteins aggregation propensity Iglesias, Valentin; Conchillo-Sole, Oscar; Batlle, Cristina; Ventura, Salvador BMC BIOINFORMATICS 1471-2105 (2019) DOI / 10.1186/s12859-019-2601-3 Gold, Green published
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Article DisProt 7.0: a major update of the database of disordered proteins Piovesan, Damiano; Tabaro, Francesco; Micetic, Ivan; Necci, Marco; Quaglia, Federica; Oldfield, Christopher J.; Aspromonte, Maria Cristina; Davey, Norman E.; Davidovic, Radoslav; Dosztanyi, Zsuzsanna; Elofsson, Arne; Gasparini, Alessandra; Hatos, Andras; K NUCLEIC ACIDS RESEARCH 0305-1048 (2017) DOI / 10.1093/nar/gkw1056 Gold DOAJ, Green published, Green accepted
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Review Prion-based nanomaterials and their emerging applications Diaz-Caballero, Marta; Rosario Fernandez, Maria; Navarro, Susanna; Ventura, Salvador PRION 1933-6896 (2018) DOI / 10.1080/19336896.2018.1521235 Green published, Gold
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Article Disulfide driven folding for a conditionally disordered protein Fraga, Hugo; Pujols, Jordi; Gil-Garcia, Marcos; Roque, Alicia; Bernardo-Seisdedos, Ganeko; Santambrogio, Carlo; Bech-Serra, Joan-Josep; Canals, Francesc; Bernado, Pau; Grandori, Rita; Millet, Oscar; Ventura, Salvador SCIENTIFIC REPORTS 2045-2322 (2017) DOI / 10.1038/s41598-017-17259-4 Green published, Gold
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Article DispHred: A Server to Predict pH-Dependent Order-Disorder Transitions in Intrinsically Disordered Proteins Santos, Jaime; Iglesias, Valentin; Pintado, Carlos; Santos-Suarez, Juan; Ventura, Salvador INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 1661-6596 (2020) DOI / 10.3390/ijms21165814 Green published, Gold
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Review Prion-like proteins and their computational identification in proteomes Batlle, Cristina; Iglesias, Valentin; Navarro, Susanna; Ventura, Salvador EXPERT REVIEW OF PROTEOMICS 1478-9450 (2017) DOI / 10.1080/14789450.2017.1304214
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Article Cavity filling mutations at the thyroxine-binding site dramatically increase transthyretin stability and prevent its aggregation Sant'Anna, Ricardo; Almeida, Maria Rosario; Varejao, Nathalia; Gallego, Pablo; Esperante, Sebastian; Ferreira, Priscila; Pereira-Henriques, Alda; Palhano, Fernando L.; de Carvalho, Mamede; Foguel, Debora; Reverter, David; Saraiva, Maria Joao; Ventura, Salv SCIENTIFIC REPORTS 2045-2322 (2017) DOI / 10.1038/srep44709 Gold DOAJ, Green published
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Article Amyloid cores in prion domains: Key regulators for prion conformational conversion Rosario Fernandez, Maria; Batlle, Cristina; Gil-Garcia, Marcos; Ventura, Salvador PRION 1933-6896 (2017) DOI / 10.1080/19336896.2017.1282020 Green published, Bronze
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Article MED15 prion-like domain forms a coiled-coil responsible for its amyloid conversion and propagation Batlle, Cristina; Calvo, Isabel; Iglesias, Valentin; Lynch, Cian J.; Gil-Garcia, Marcos; Serrano, Manuel; Ventura, Salvador COMMUNICATIONS BIOLOGY (2021) DOI / 10.1038/s42003-021-01930-8 Gold, Green published
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Review Computational prediction of protein aggregation: Advances in proteomics, conformation-specific algorithms and biotechnological applications Santos, Jaime; Pujols, Jordi; Pallares, Irantzu; Iglesias, Valentin; Ventura, Salvador COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL 2001-0370 (2020) DOI / 10.1016/j.csbj.2020.05.026 Green published, Gold
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Article Tolcapone, a potent aggregation inhibitor for the treatment of familial leptomeningeal amyloidosis Pinheiro, Francisca; Varejao, Nathalia; Esperante, Sebastian; Santos, Jaime; Velazquez-Campoy, Adrian; Reverter, David; Pallares, Irantzu; Ventura, Salvador FEBS JOURNAL 1742-464X (2020) DOI / 10.1111/febs.15339 Green accepted
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Article SolupHred: a server to predict the pH-dependent aggregation of intrinsically disordered proteins Pintado, Carlos; Santos, Jaime; Iglesias, Valentin; Ventura, Salvador BIOINFORMATICS 1367-4803 (2021) DOI / 10.1093/bioinformatics/btaa909
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Article DispHScan: A Multi-Sequence Web Tool for Predicting Protein Disorder as a Function of pH Pintado-Grima, Carlos; Iglesias, Valentin; Santos, Jaime; Uversky, Vladimir N.; Ventura, Salvador BIOMOLECULES (2021) DOI / 10.3390/biom11111596 Green published, Gold
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Article A single cysteine post-translational oxidation suffices to compromise globular proteins kinetic stability and promote amyloid formation Marinelli, Patrizia; Navarro, Susanna; Grana-Montes, Ricardo; Bano-Polo, Manuel; Rosario Fernandez, Maria; Papaleo, Elena; Ventura, Salvador REDOX BIOLOGY 2213-2317 (2018) DOI / 10.1016/j.redox.2017.10.022 Green published, Gold
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Article Disease-associated mutations impacting BC-loop flexibility trigger long-range transthyretin tetramer destabilization and aggregation Esperante, Sebastian A.; Varejao, Nathalia; Pinheiro, Francisca; Sant'Anna, Ricardo; Roman Luque-Ortega, Juan; Alfonso, Carlos; Sora, Valentina; Papaleo, Elena; Rivas, German; Reverter, David; Ventura, Salvador JOURNAL OF BIOLOGICAL CHEMISTRY 0021-9258 (2021) DOI / 10.1016/j.jbc.2021.101039 Green published, Gold
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Article Protein Environment: A Crucial Triggering Factor in Josephin Domain Aggregation: The Role of 2,2,2-Trifluoroethanol Visentin, Cristina; Navarro, Susanna; Grasso, Gianvito; Regonesi, Maria Elena; Deriu, Marco Agostino; Tortora, Paolo; Ventura, Salvador INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 1661-6596 (2018) DOI / 10.3390/ijms19082151 Green published, Gold, Green submitted
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Article Cryptic amyloidogenic regions in intrinsically disordered proteins: Function and disease association Santos, Jaime; Pallares, Irantzu; Iglesias, Valentin; Ventura, Salvador COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL 2001-0370 (2021) DOI / 10.1016/j.csbj.2021.07.019 Gold
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Article Functionalized Prion-Inspired Amyloids for Biosensor Applications Diaz-Caballero, Marta; Navarro, Susanna; Ventura, Salvador BIOMACROMOLECULES 1525-7797 (2021) DOI / 10.1021/acs.biomac.1c00222 Hybrid, Green published
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Article Soluble Assemblies in the Fibrillation Pathway of Prion-Inspired Artificial Functional Amyloids are Highly Cytotoxic Diaz-Caballero, Marta; Navarro, Susanna; Ventura, Salvador BIOMACROMOLECULES 1525-7797 (2020) DOI / 10.1021/acs.biomac.0c00271
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Article A pyrene-inhibitor fluorescent probe with large Stokes shift for the staining of A(1-42), -synuclein, and amylin amyloid fibrils as well as amyloid-containing Staphylococcus aureus biofilms Mahia, Alejandro; Conde-Gimenez, Maria; Salillas, Sandra; Pallares, Irantzu; Galano-Frutos, Juan J.; Lasa, Inigo; Ventura, Salvador; Diaz-de-Villegas, Maria D.; Galvez, Jose A.; Sancho, Javier ANALYTICAL AND BIOANALYTICAL CHEMISTRY 1618-2642 (2019) DOI / 10.1007/s00216-018-1433-8
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Article Multifunctional Amyloid Oligomeric Nanoparticles for Specific Cell Targeting and Drug Delivery Wang, Weiqiang; Azizyan, Rafayel A.; Garro, Adriana; Kajava, Andrey, V; Ventura, Salvador BIOMACROMOLECULES 1525-7797 (2020) DOI / 10.1021/acs.biomac.0c01103
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Article Plasticity in the Oxidative Folding Pathway of the High Affinity Nerita Versicolor Carboxypeptidase Inhibitor (NvCI) Esperante, Sebastian A.; Covaleda, Giovanni; Trejo, Sebastian A.; Bronsoms, Silvia; Aviles, Francesc X.; Ventura, Salvador SCIENTIFIC REPORTS 2045-2322 (2017) DOI / 10.1038/s41598-017-05657-7 Gold DOAJ, Green published
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Article Pathological ATX3 Expression Induces Cell Perturbations in E. coli as Revealed by Biochemical and Biophysical Investigations Ami, Diletta; Sciandrone, Barbara; Mereghetti, Paolo; Falvo, Jacopo; Catelani, Tiziano; Visentin, Cristina; Tortora, Paolo; Ventura, Salvador; Natalello, Antonino; Regonesi, Maria Elena INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 1661-6596 (2021) DOI / 10.3390/ijms22020943 Gold DOAJ, Green published
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Review Prion domains as a driving force for the assembly of functional nanomaterials Wang, Weiqiang; Ventura, Salvador PRION 1933-6896 (2020) DOI / 10.1080/19336896.2020.1785659 Gold, Green published
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Article Insight into the specificity and severity of pathogenic mechanisms associated with missense mutations through experimental and structural perturbation analyses Medina-Carmona, Encarnacion; Betancor-Fernandez, Isabel; Santos, Jaime; Mesa-Torres, Noel; Grottelli, Silvia; Batlle, Cristina; Naganathan, Athi N.; Oppici, Elisa; Cellini, Barbara; Ventura, Salvador; Salido, Eduardo; Pey, Angel L. HUMAN MOLECULAR GENETICS 0964-6906 (2019) DOI / 10.1093/hmg/ddy323 Bronze

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