Clinical Medicine

Listando 49 trabajos del autor/autora 38

Lista de trabajos en el área Clinical Medicine

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Article A framework to rank genomic alterations as targets for cancer precision medicine: the ESMO Scale for Clinical Actionability of molecular Targets (ESCAT) Mateo, J.; Chakravarty, D.; Dienstmann, R.; Jezdic, S.; Gonzalez-Perez, A.; Lopez-Bigas, N.; Ng, C. K. Y.; Bedard, P. L.; Tortora, G.; Douillard, J. -Y.; Van Allen, E. M.; Schultz, N.; Swanton, C.; Andre, F.; Pusztai, L. ANNALS OF ONCOLOGY 0923-7534 (2018) DOI / 10.1093/annonc/mdy263 Bronze, Green published

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Article Concordance of blood- and tumor-based detection of RAS mutations to guide anti-EGFR therapy in metastatic colorectal cancer Grasselli, J.; Elez, E.; Caratu, G.; Matito, J.; Santos, C.; Macarulla, T.; Vidal, J.; Garcia, M.; Vieitez, J. M.; Paez, D.; Falco, E.; Lopez Lopez, C.; Aranda, E.; Jones, F.; Sikri, V.; Nuciforo, P.; Fasani, R.; Tabernero, J.; Montagut, C.; Azuara, D.; Di ANNALS OF ONCOLOGY 0923-7534 (2017) DOI / 10.1093/annonc/mdx112 Green published, Hybrid

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Article TET2 controls chemoresistant slow-cycling cancer cell survival and tumor recurrence Puig, Isabel; Tenbaum, Stephan P.; Chicote, Irene; Arques, Oriol; Martinez-Quintanilla, Jordi; Cuesta-Borras, Estefania; Ramirez, Lorena; Gonzalo, Pilar; Soto, Atenea; Aguilar, Susana; Eguizabal, Cristina; Caratu, Ginevra; Prat, Aleix; Argiles, Guillem; La JOURNAL OF CLINICAL INVESTIGATION 0021-9738 (2018) DOI / 10.1172/jci96393 Bronze, Green published

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Review Recommendations for the use of next-generation sequencing (NGS) for patients with metastatic cancers: a report from the ESMO Precision Medicine Working Group Mosele, F.; Remon, J.; Mateo, J.; Westphalen, C. B.; Barlesi, F.; Lolkema, M. P.; Normanno, N.; Scarpa, A.; Robson, M.; Meric-Bernstam, F.; Wagle, N.; Stenzinger, A.; Bonastre, J.; Bayle, A.; Michiels, S.; Bieche, I; Rouleau, E.; Jezdic, S.; Douillard, J-Y ANNALS OF ONCOLOGY 0923-7534 (2020) DOI / 10.1016/j.annonc.2020.07.014 Green published, Bronze

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Letter Support systems to guide clinical decision-making in precision oncology: The Cancer Core Europe Molecular Tumor Board Portal Tamborero, David; Dienstmann, Rodrigo; Rachid, Maan Haj; Boekel, Jorrit; Baird, Richard; Brana, Irene; de Petris, Luigi; Yachnin, Jeffrey; Massard, Christophe; Opdam, Frans L.; Schlenk, Richard; Vernieri, Claudio; Garralda, Elena; Masucci, Michele; Villalo NATURE MEDICINE 1078-8956 (2020) DOI / 10.1038/s41591-020-0969-2

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Article Efficacy of Sym004 in Patients With Metastatic Colorectal Cancer With Acquired Resistance to Anti-EGFR Therapy and Molecularly Selected by Circulating Tumor DNA Analyses A Phase 2 Randomized Clinical Trial Montagut, Clara; Argiles, Guillem; Ciardiello, Fortunato; Poulsen, Thomas T.; Dienstmann, Rodrigo; Kragh, Michael; Kopetz, Scott; Lindsted, Trine; Ding, Cliff; Vidal, Joana; Clausell-Tormos, Jenifer; Siravegna, Giulia; Sanchez-Martin, Francisco J.; Koefoed JAMA ONCOLOGY 2374-2437 (2018) DOI / 10.1001/jamaoncol.2017.5245 Green published, Bronze

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Editorial Material CANCER A precision approach to tumour treatment Dienstmann, Rodrigo; Tabernero, Josep NATURE 0028-0836 (2017) DOI / 10.1038/nature23101 Bronze

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Review Consensus molecular subtypes and the evolution of precision medicine in colorectal cancer Dienstmann, Rodrigo; Vermeulen, Louis; Guinney, Justin; Kopetz, Scott; Tejpar, Sabine; Tabernero, Josep NATURE REVIEWS CANCER 1474-175X (2017) DOI / 10.1038/nrc.2016.126

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Article A CT-based Radiomics Signature Is Associated with Response to Immune Checkpoint Inhibitors in Advanced Solid Tumors Ligero, Marta; Garcia-Ruiz, Alonso; Viaplana, Cristina; Villacampa, Guillermo; Raciti, Maria, V; Landa, Jaid; Matos, Ignacio; Martin-Liberal, Juan; Ochoa-de-Olza, Maria; Hierro, Cinta; Mateo, Joaquin; Gonzalez, Macarena; Morales-Barrera, Rafael; Suarez, Cr RADIOLOGY 0033-8419 (2021) DOI / 10.1148/radiol.2021200928

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Article Impact of COVID-19 on social media as perceived by the oncology community: results from a survey in collaboration with the European Society for Medical Oncology (ESMO) and the OncoAlert Network Morgan, G.; Tagliamento, M.; Lambertini, M.; Devnani, B.; Westphalen, B.; Dienstmann, R.; Bozovic-Spasojevic, I; Calles, A.; Criscitiello, C.; Curioni, A.; Garcia, A. M.; Lamarca, A.; Pilotto, S.; Scheffler, M.; Strijbos, M.; Wong, R.; De Azambuja, E.; Pet ESMO OPEN (2021) DOI / 10.1016/j.esmoop.2021.100104 Gold DOAJ, Green published

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Article Relative contribution of clinicopathological variables, genomic markers, transcriptomic subtyping and microenvironment features for outcome prediction in stage II/III colorectal cancer Dienstmann, R.; Villacampa, G.; Sveen, A.; Mason, M. J.; Niedzwiecki, D.; Nesbakken, A.; Moreno, V.; Warren, R. S.; Lothe, R. A.; Guinney, J. ANNALS OF ONCOLOGY 0923-7534 (2019) DOI / 10.1093/annonc/mdz287 Green published, Gold other

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Article Capturing Hyperprogressive Disease with Immune-Checkpoint Inhibitors Using RECIST 1.1 Criteria Matos, Ignacio; Martin-Liberal, Juan; Garcia-Ruiz, Alonso; Hierro, Cinta; Ochoa de Olza, Maria; Viaplana, Cristina; Azaro, Analia; Vieito, Maria; Brana, Irene; Mur, Gemma; Ros, Javier; Mateos, Jose; Villacampa, Guillermo; Berche, Roger; Oliveira, Mafalda; CLINICAL CANCER RESEARCH 1078-0432 (2020) DOI / 10.1158/1078-0432.ccr-19-2226 Bronze

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Article RBMS1 Suppresses Colon Cancer Metastasis through Targeted Stabilization of Its mRNA Regulon Yu, Johnny; Navickas, Albertas; Asgharian, Hosseinali; Culbertson, Bruce; Fish, Lisa; Garcia, Kristle; Olegario, John Paolo; Dermit, Maria; Dodel, Martin; Hanisch, Benjamin; Luo, Yikai; Weinberg, Ethan M.; Dienstmann, Rodrigo; Warren, Robert S.; Mardakheh, CANCER DISCOVERY 2159-8274 (2020) DOI / 10.1158/2159-8290.cd-19-1375

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Article Evolving Landscape of Molecular Prescreening Strategies for Oncology Early Clinical Trials Dienstmann, Rodrigo; Garralda, Elena; Aguilar, Susana; Sala, Gemma; Viaplana, Cristina; Ruiz-Pace, Fiorella; Gonzalez-Zorelle, Jenifer; Grazia LoGiacco, Deborah; Ogbah, Zighereda; Ramos Masdeu, Laia; Mancuso, Francesco; Fasani, Roberta; Jimenez, Jose; Mart JCO PRECISION ONCOLOGY (2020) DOI / 10.1200/po.19.00398 Gold other, Green published

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Article A Pan-cancer Landscape of Interactions between Solid Tumors and Infiltrating Immune Cell Populations Tamborero, David; Rubio-Perez, Carlota; Muinos, Ferran; Sabarinathan, Radhakrishnan; Piulats, Josep M.; Muntasell, Aura; Dienstmann, Rodrigo; Lopez-Bigas, Nuria; Gonzalez-Perez, Abel CLINICAL CANCER RESEARCH 1078-0432 (2018) DOI / 10.1158/1078-0432.ccr-17-3509 Bronze, Green submitted

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Article Fusobacterium nucleatum persistence and risk of recurrence after preoperative treatment in locally advanced rectal cancer Serna, G.; Ruiz-Pace, F.; Hernando, J.; Alonso, L.; Fasani, R.; Landolfi, S.; Comas, R.; Jimenez, J.; Elez, E.; Bullman, S.; Tabernero, J.; Capdevila, J.; Dienstmann, R.; Nuciforo, P. ANNALS OF ONCOLOGY 0923-7534 (2020) DOI / 10.1016/j.annonc.2020.06.003 Gold other, Green published

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Article Genetic Alterations in the PI3K/AKT Pathway and Baseline AKT Activity Define AKT Inhibitor Sensitivity in Breast Cancer Patient-derived Xenografts Gris-Oliver, Albert; Palafox, Marta; Monserrat, Laia; Braso-Maristany, Fara; Odena, Andreu; Sanchez-Guixe, Monica; Ibrahim, Yasir H.; Villacampa, Guillermo; Grueso, Judit; Pars, Mireia; Guzman, Marta; Rodriguez, Olga; Bruna, Alejandra; Hirst, Caroline S.; CLINICAL CANCER RESEARCH 1078-0432 (2020) DOI / 10.1158/1078-0432.ccr-19-3324 Bronze, Green accepted

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Article Phase I prognostic online (PIPO): A web tool to improve patient selection for oncology early phase clinical trials Matos, Ignacio; Villacampa, Guillermo; Hierro, Cinta; Martin-Liberal, Juan; Berche, Roger; Pedrola, Anna; Brana, Irene; Azaro, Analia; Vieito, Maria; Saavedra, Omar; Gardeazabal, Itziar; Hernando-Calvo, Alberto; Alonso, Guzman; Galvao, Vladimir; de Olza, M EUROPEAN JOURNAL OF CANCER 0959-8049 (2021) DOI / 10.1016/j.ejca.2021.05.040 Hybrid

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Article Association of premenopausal risk-reducing salpingo-oophorectomy with breast cancer risk in BRCA1/2 mutation carriers: Maximising bias-reduction Stjepanovic, Neda; Villacampa, Guillermo; Nead, Kevin T.; Torres-Esquius, Sara; Melis, Guadalupe G.; Nathanson, Katherine L.; Teule, Alexandre; Brunet, Joan; y Cajal, Teresa R.; Llort, Gemma; Dienstmann, Rodrigo; Rue, Montserrat; Domchek, Susan M.; Balmana EUROPEAN JOURNAL OF CANCER 0959-8049 (2020) DOI / 10.1016/j.ejca.2020.03.009

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Editorial Material Is It Time to Implement Adjuvant Targeted Therapy in EGFR-Mutant Non-Small-Cell Lung Cancer? Kulkarni, Amit A.; Naqash, Abdul Rafeh; Puri, Sonam; Dienstmann, Rodrigo JCO PRECISION ONCOLOGY (2021) DOI / 10.1200/po.20.00460

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Article Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell-like phenotype Lupo, Barbara; Sassi, Francesco; Pinnelli, Marika; Galimi, Francesco; Zanella, Eugenia R.; Vurchio, Valentina; Migliardi, Giorgia; Gagliardi, Paolo Armando; Puliafito, Alberto; Manganaro, Daria; Luraghi, Paolo; Kragh, Michael; Pedersen, Mikkel W.; Horak, I SCIENCE TRANSLATIONAL MEDICINE 1946-6234 (2020) DOI / 10.1126/scitranslmed.aax8313

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Article The temporal mutational and immune tumour microenvironment remodelling of HER2-negative primary breast cancers De Mattos-Arruda, Leticia; Cortes, Javier; Blanco-Heredia, Juan; Tiezzi, Daniel G.; Villacampa, Guillermo; Goncalves-Ribeiro, Samuel; Pare, Laia; Souza, Carla Anjos; Ortega, Vanesa; Sammut, Stephen-John; Cusco, Pol; Fasani, Roberta; Chin, Suet-Feung; Perez NPJ BREAST CANCER (2021) DOI / 10.1038/s41523-021-00282-0 Green published, Gold

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Article Patient-Derived Organoids from Multiple Colorectal Cancer Liver Metastases Reveal Moderate Intra-patient Pharmacotranscriptomic Heterogeneity Bruun, Jarle; Kryeziu, Kushtrim; Eide, Peter W.; Moosavi, Seyed H.; Eilertsen, Ina A.; Langerud, Jonas; Rosok, Bard; Totland, Max Z.; Brunsell, Tuva H.; Pellinen, Teijo; Saarela, Jani; Bergsland, Christian H.; Palmer, Hector G.; Brudvik, Kristoffer W.; Gur CLINICAL CANCER RESEARCH 1078-0432 (2020) DOI / 10.1158/1078-0432.ccr-19-3637 Bronze

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Article Transcriptional Subtyping and CD8 Immunohistochemistry Identifies Patients With Stage II and III Colorectal Cancer With Poor Prognosis Who Benefit From Adjuvant Chemotherapy Allen, Wendy L.; Dunne, Philip D.; Mcdade, Simon; Scanlon, Enya; Loughrey, Maurice; Coleman, Helen G.; McCann, Christopher; McLaughlin, Kristy; Nemeth, Zsuzsanna; Syed, Najeeb Ashraf; Jithesh, Puthen Veettil; Arthur, Ken; Wilson, Richard; Coyle, Vicky M.; JCO PRECISION ONCOLOGY (2018) DOI / 10.1200/po.17.00241 Green accepted, Green published, Gold other

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Article Colorectal premalignancy is associated with consensus molecular subtypes 1 and 2 Chang, K.; Willis, J. A.; Reumers, J.; Taggart, M. W.; Lucas, F. A. San; Thirumurthi, S.; Kanth, P.; Delker, D. A.; Hagedorn, C. H.; Lynch, P. M.; Ellis, L. M.; Hawk, E. T.; Scheet, P. A.; Kopetz, S.; Arts, J.; Guinney, J.; Dienstmann, R.; Vilar, E. ANNALS OF ONCOLOGY 0923-7534 (2018) DOI / 10.1093/annonc/mdy337 Green published, Bronze

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Article Molecular Subtyping Combined with Biological Pathway Analyses to Study Regorafenib Response in Clinically Relevant Mouse Models of Colorectal Cancer Lafferty, Adam; O'Farrell, Alice C.; Migliardi, Giorgia; Khemka, Niraj; Lindner, Andreas U.; Sassi, Francesco; Zanella, Eugenia R.; Salvucci, Manuela; Vanderheyden, Evy; Modave, Elodie; Boeckx, Bram; Halang, Luise; Betge, Johannes; Ebert, Matthias P. A.; D CLINICAL CANCER RESEARCH 1078-0432 (2021) DOI / 10.1158/1078-0432.ccr-21-0818

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Article Colorectal Cancer Consensus Molecular Subtypes Translated to Preclinical Models Uncover Potentially Targetable Cancer Cell Dependencies Sveen, Anita; Bruun, Jarle; Eide, Peter W.; Eilertsen, Ina A.; Ramirez, Lorena; Murumagi, Astrid; Arjama, Mariliina; Danielsen, Stine A.; Kryeziu, Kushtrim; Elez, Elena; Tabernero, Josep; Guinney, Justin; Palmer, Hector G.; Nesbakken, Arild; Kallioniemi, O CLINICAL CANCER RESEARCH 1078-0432 (2018) DOI / 10.1158/1078-0432.ccr-17-1234 Green published, Bronze

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Review Precision oncology: separating the wheat from the chaff Remon, Jordi; Dienstmann, Rodrigo ESMO OPEN (2018) DOI / 10.1136/esmoopen-2018-000446 Gold DOAJ, Green published

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Editorial Material Predictive modeling in colorectal cancer: time to move beyond consensus molecular subtypes Sveen, A.; Cremolini, C.; Dienstmann, R. ANNALS OF ONCOLOGY 0923-7534 (2019) DOI / 10.1093/annonc/mdz412 Bronze

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Review The Evolving Role of Consensus Molecular Subtypes: a Step Beyond Inpatient Selection for Treatment of Colorectal Cancer Ros, Javier; Baraibar, Iosune; Martini, Giulia; Salva, Francesc; Saoudi, Nadia; Luis Cuadra-Urteaga, Jose; Dienstmann, Rodrigo; Tabernero, Josep; Elez, Elena CURRENT TREATMENT OPTIONS IN ONCOLOGY 1527-2729 (2021) DOI / 10.1007/s11864-021-00913-5

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Editorial Material Precision Therapy in RAS Mutant Colorectal Cancer Dienstmann, Rodrigo; Connor, Kate; Byrne, Annette T. GASTROENTEROLOGY 0016-5085 (2020) DOI / 10.1053/j.gastro.2019.12.051 Bronze

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Article Evolution of Angiogenic Factors in Pregnant Patients with Breast Cancer Treated with Chemotherapy Saura, Cristina; Sanchez, Olga; Martinez, Sandra; Dominguez, Carmen; Dienstmann, Rodrigo; Ruiz-Pace, Fiorella; Cespedes, Maria Concepcio; Penuelas, Angeles; Cortes, Javier; Llurba, Elisa; Cordoba, Octavi CANCERS (2021) DOI / 10.3390/cancers13040923 Gold DOAJ

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Article Minimizing acquisition-related radiomics variability by image resampling and batch effect correction to allow for large-scale data analysis Ligero, Marta; Jordi-Ollero, Olivia; Bernatowicz, Kinga; Garcia-Ruiz, Alonso; Delgado-Munoz, Eric; Leiva, David; Mast, Richard; Suarez, Cristina; Sala-Llonch, Roser; Calvo, Nahum; Escobar, Manuel; Navarro-Martin, Arturo; Villacampa, Guillermo; Dienstmann, EUROPEAN RADIOLOGY 0938-7994 (2020) DOI / 10.1007/s00330-020-07174-0 Gold other, Green published

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Article Prediction of overall survival in stage II and III colon cancer beyond TNM system: a retrospective, pooled biomarker study Dienstmann, R.; Mason, M. J.; Sinicrope, F. A.; Phipps, A. I.; Tejpar, S.; Nesbakken, A.; Danielsen, S. A.; Sveen, A.; Buchanan, D. D.; Clendenning, M.; Rosty, C.; Bot, B.; Alberts, S. R.; Jessup, J. Milburn; Lothe, R. A.; Delorenzi, M.; Newcomb, P. A.; Sa ANNALS OF ONCOLOGY 0923-7534 (2017) DOI / 10.1093/annonc/mdx052 Green published, Gold other