Clinical Medicine


  Listando 36 trabajos del autor/autora 38
Lista de trabajos en el área Clinical Medicine
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Article Clinical Portrait of the SARS-CoV-2 Epidemic in European Patients with Cancer Pinato, David J.; Zambelli, Alberto; Aguilar-Company, Juan; Bower, Mark; Sng, Christopher C. T.; Salazar, Ramon; Bertuzzi, Alexia; Brunet, Joan; Mesia, Ricard; Segui, Elia; Biello, Federica; Generali, Daniele; Grisanti, Salvatore; Rizzo, Gianpiero; Liberti CANCER DISCOVERY 2159-8274 (2020) DOI / 10.1158/2159-8290.cd-20-0773 Green published, Bronze
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Article Trajectories of alcohol consumption during life and the risk of developing breast cancer Donat-Vargas, Carolina; Guerrero-Zotano, Angel; Casas, Ana; Manuel Baena-Canada, Jose; Lope, Virginia; Antolin, Silvia; Angel Garcia-Saenz, Jose; Bermejo, Begona; Munoz, Montserrat; Ramos, Manuel; de Juan, Ana; Jara Sanchez, Carlos; Sanchez-Rovira, Pedro; BRITISH JOURNAL OF CANCER 0007-0920 (2021) DOI / 10.1038/s41416-021-01492-w Hybrid
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Article Association Between Germline Mutations in &ITBRF1&IT, a Subunit of the RNA Polymerase III Transcription Complex, and Hereditary Colorectal Cancer Bellido, Fernando; Sowada, Nadine; Mur, Pilar; Lazaro, Conxi; Pons, Tirso; Valdes-Mas, Rafael; Pineda, Marta; Aiza, Gemma; Iglesias, Silvia; Soto, Jose Luis; Urioste, Miguel; Caldes, Trinidad; Balbin, Milagros; Blay, Pilar; Rueda, Daniel; Duran, Mercedes; GASTROENTEROLOGY 0016-5085 (2018) DOI / 10.1053/j.gastro.2017.09.005
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Article Metformin Is a Direct SIRT1-Activating Compound: Computational Modeling and Experimental Validation Cuyas, Elisabet; Verdura, Sara; Llorach-Pares, Laura; Fernandez-Arroyo, Salvador; Joven, Jorge; Martin-Castillo, Begona; Bosch-Barrera, Joaquim; Brunet, Joan; Nonell-Canals, Alfons; Sanchez-Martinez, Melchor; Menendez, Javier A. FRONTIERS IN ENDOCRINOLOGY 1664-2392 (2018) DOI / 10.3389/fendo.2018.00657 Gold DOAJ, Green published
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Review New perspectives on screening and early detection of endometrial cancer Costas, Laura; Frias-Gomez, Jon; Guardiola, Magdalena; Benavente, Yolanda; Pineda, Marta; Pavon, Miquel A.; Martinez, Jose M.; Climent, Maite; Barahona, Marc; Canet, Julia; Paytubi, Sonia; Salinas, Monica; Palomero, Luis; Bianchi, Ilaria; Reventos, Jaume; INTERNATIONAL JOURNAL OF CANCER 0020-7136 (2019) DOI / 10.1002/ijc.32514
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Article TP53, a gene for colorectal cancer predisposition in the absence of Li-Fraumeni-associated phenotypes Terradas, Mariona; Mur, Pilar; Belhadj, Sami; Woodward, Emma R.; Burghel, George J.; Munoz-Torres, Pau M.; Quintana, Isabel; Navarro, Matilde; Brunet, Joan; Lazaro, Conxi; Pineda, Marta; Moreno, Victor; Capella, Gabriel; Evans, D. Gareth R.; Valle, Laura GUT 0017-5749 (2021) DOI / 10.1136/gutjnl-2020-321825
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Article Primary breast cancer and health related quality of life in Spanish women: The EpiGEICAM case-control study Fernandez de Larrea-Baz, Nerea; Perez-Gomez, Beatriz; Guerrero-Zotano, Angel; Maria Casas, Ana; Bermejo, Begona; Manuel Baena-Canada, Jose; Antolin, Silvia; Sanchez-Rovira, Pedro; Ramos Vazquez, Manuel; Angel Garcia-Saenz, Jose; Anton, Antonio; Munoz, Mont SCIENTIFIC REPORTS 2045-2322 (2020) DOI / 10.1038/s41598-020-63637-w Green published, Gold other
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Article Silibinin and SARS-CoV-2: Dual Targeting of Host Cytokine Storm and Virus Replication Machinery for Clinical Management of COVID-19 Patients Bosch-Barrera, Joaquim; Martin-Castillo, Begona; Buxo, Maria; Brunet, Joan; Encinar, Jose Antonio; Menendez, Javier A. JOURNAL OF CLINICAL MEDICINE (2020) DOI / 10.3390/jcm9061770 Gold, Green published
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Article Non-Lynch Familial and Early-Onset Colorectal Cancer Explained by Accumulation of Low-Risk Genetic Variants Mur, Pilar; Bonifaci, Nuria; Diez-Villanueva, Anna; Munte, Elisabet; Henar Alonso, Maria; Obon-Santacana, Mireia; Aiza, Gemma; Navarro, Matilde; Pinol, Virginia; Brunet, Joan; Tomlinson, Ian; Capella, Gabriel; Moreno, Victor; Valle, Laura CANCERS (2021) DOI / 10.3390/cancers13153857 Green published, Gold
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Article Association of premenopausal risk-reducing salpingo-oophorectomy with breast cancer risk in BRCA1/2 mutation carriers: Maximising bias-reduction Stjepanovic, Neda; Villacampa, Guillermo; Nead, Kevin T.; Torres-Esquius, Sara; Melis, Guadalupe G.; Nathanson, Katherine L.; Teule, Alexandre; Brunet, Joan; y Cajal, Teresa R.; Llort, Gemma; Dienstmann, Rodrigo; Rue, Montserrat; Domchek, Susan M.; Balmana EUROPEAN JOURNAL OF CANCER 0959-8049 (2020) DOI / 10.1016/j.ejca.2020.03.009
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Article Presenting Features and Early Mortality from SARS-CoV-2 Infection in Cancer Patients during the Initial Stage of the COVID-19 Pandemic in Europe Pinato, David J.; Lee, Alvin J. X.; Biello, Federica; Segui, Elia; Aguilar-Company, Juan; Carbo, Anna; Bruna, Riccardo; Bower, Mark; Rizzo, Gianpiero; Benafif, Sarah; Carmona, Carme; Chopra, Neha; Cruz, Claudia Andrea; D'Avanzo, Francesca; Evans, Joanne S. CANCERS (2020) DOI / 10.3390/cancers12071841 Green published, Gold
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Article The C Allele of ATM rs11212617 Associates With Higher Pathological Complete Remission Rate in Breast Cancer Patients Treated With Neoadjuvant Metformin Cuyas, Elisabet; Buxo, Maria; Ferri Iglesias, Maria Jose; Verdura, Sara; Pemas, Sonia; Dorca, Joan; Alvarez, Isabel; Martinez, Susana; Perez-Garcia, Jose Manuel; Batista-Lopez, Norberto; Rodriguez-Sanchez, Cesar A.; Amillano, Kepa; Dominguez, Severina; Luq FRONTIERS IN ONCOLOGY 2234-943X (2019) DOI / 10.3389/fonc.2019.00193 Gold DOAJ, Green published
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Article Tumors defective in homologous recombination rely on oxidative metabolism: relevance to treatments with PARP inhibitors Lahiguera, Alvaro; Hyrossova, Petra; Figueras, Agnes; Garzon, Diana; Moreno, Roger; Soto-Cerrato, Vanessa; McNeish, Iain; Serra, Violeta; Lazaro, Conxi; Barretina, Pilar; Brunet, Joan; Menendez, Javier; Matias-Guiu, Xavier; Vidal, August; Villanueva, Alber EMBO MOLECULAR MEDICINE 1757-4676 (2020) DOI / 10.15252/emmm.201911217 Gold DOAJ, Green published
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Article Specialist palliative and end-of-life care for patients with cancer and SARS-CoV-2 infection: a European perspective Soosaipillai, Gehan; Wu, Anjui; Dettorre, Gino M.; Diamantis, Nikolaos; Chester, John; Moss, Charlotte; Aguilar-Company, Juan; Bower, Mark; Sng, Christopher C. T.; Salazar, Ramon; Brunet, Joan; Jones, Eleanor; Mesia, Ricard; Jackson, Amanda; Mukherjee, Uma THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY 1758-8340 (2021) DOI / 10.1177/17588359211042224 Green published, Gold
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Article Germline mutations in the spindle assembly checkpoint genes BUB1 and BUB3 are infrequent in familial colorectal cancer and polyposis Mur, Pilar; de Voer, Richarda M.; Olivera-Salguero, Ruben; Rodriguez-Perales, Sandra; Pons, Tirso; Setien, Fernando; Aiza, Gemma; Valdes-Mas, Rafael; Bertini, Angelo; Pineda, Marta; Vreede, Lilian; Navarro, Matilde; Iglesias, Silvia; Gonzalez, Sara; Brunet MOLECULAR CANCER (2018) DOI / 10.1186/s12943-018-0762-8 Green published, Gold
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Article Metformin induces a fasting- and antifolate-mimicking modification of systemic host metabolism in breast cancer patients Cuyas, Elisabet; Fernandez-Arroyo, Salvador; Buxo, Maria; Pernas, Sonia; Dorca, Joan; Alvarez, Isabel; Martinez, Susana; Manuel Perez-Garcia, Jose; Batista-Lopez, Norberto; Rodriguez-Sanchez, Cesar A.; Amillano, Kepa; Dominguez, Severina; Luque, Maria; Mor AGING-US 1945-4589 (2019) DOI / 10.18632/aging.101960 Green published
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Article A retrospective, multicenter study of the efficacy of lapatinib plus trastuzumab in HER2-positive metastatic breast cancer patients previously treated with trastuzumab, lapatinib, or both: the Trastyvere study Gavila, J.; de la Haba, J.; Bermejo, B.; Rodriguez-Lescure, A.; Anton, A.; Ciruelos, E.; Brunet, J.; Munoz-Couselo, E.; Santisteban, M.; Rodriguez Sanchez, C. A.; Santaballa, A.; Sanchez Rovira, P.; Garcia Saenz, J. A.; Ruiz-Borrego, M.; Guerrero-Zotano, A CLINICAL & TRANSLATIONAL ONCOLOGY 1699-048X (2020) DOI / 10.1007/s12094-019-02145-4
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Article DGCR8 and the six hit, three-step model of schwannomatosis Nogue, Clara; Chong, Anne-Sophie; Grau, Elia; Han, Hyerim; Dorca, Eduard; Roca, Carla; Mosquera, Jose Luis; Lazaro, Conxi; Foulkes, William D.; Brunet, Joan; Rivera, Barbara ACTA NEUROPATHOLOGICA 0001-6322 (2021) DOI / 10.1007/s00401-021-02387-z
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Article Elucidating the molecular basis of MSH2-deficienttumors by combined germline and somatic analysis Vargas-Parra, Gardenia M.; Gonzalez-Acosta, Maribel; Thompson, Bryony A.; Gomez, Carolina; Fernandez, Anna; Damaso, Estela; Pons, Tirso; Morak, Monika; del Valle, Jesus; Iglesias, Silvia; Velasco, Angela; Solanes, Ares; Sanjuan, Xavier; Padilla, Natalia; d INTERNATIONAL JOURNAL OF CANCER 0020-7136 (2017) DOI / 10.1002/ijc.30820 Green published, Bronze
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Article Psychosocial problems in women attending French, German and Spanish genetics clinics before and after targeted or multigene testing results: an observational prospective study Bredart, Anne; Kop, Jean-Luc; Dick, Julia; Cano, Alejandra; de Pauw, Antoine; Anota, Amelie; Brunet, Joan; Devilee, Peter; Stoppa-Lyonnet, Dominique; Schmutzler, Rita; Dolbeault, Sylvie BMJ OPEN 2044-6055 (2019) DOI / 10.1136/bmjopen-2019-029926 Gold other, Green published
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Article Neoadjuvant Metformin Added to Systemic Therapy Decreases the Proliferative Capacity of Residual Breast Cancer Lopez-Bonet, Eugeni; Buxo, Maria; Cuyas, Elisabet; Pernas, Sonia; Dorca, Joan; Alvarez, Isabel; Martinez, Susana; Manuel Perez-Garcia, Jose; Batista-Lopez, Norberto; Rodriguez-Sanchez, Cesar A.; Amillano, Kepa; Dominguez, Severina; Luque, Maria; Morilla, I JOURNAL OF CLINICAL MEDICINE (2019) DOI / 10.3390/jcm8122180 Green published, Gold
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Article Germline variation in O-6-methylguanine-DNA methyltransferase (MGMT) as cause of hereditary colorectal cancer Belhadj, Sami; Moutinho, Catia; Mur, Pilar; Setien, Fernando; Llinas-Arias, Pere; Perez-Salvia, Montserrat; Pons, Tirso; Pineda, Marta; Brunet, Joan; Navarro, Matilde; Capella, Gabriel; Esteller, Manel; Valle, Laura CANCER LETTERS 0304-3835 (2019) DOI / 10.1016/j.canlet.2019.01.019 Green published, Green accepted, Gold other
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Review Sensitivity of cervico-vaginal cytology in endometrial carcinoma: A systematic review and meta-analysis Frias-Gomez, Jon; Benavente, Yolanda; Ponce, Jordi; Brunet, Joan; Ibanez, Raquel; Peremiquel-Trillas, Paula; Baixeras, Nuria; Zanca, Alba; Piulats, Josep Maria; Aytes, Alvaro; Matias-Guiu, Xavier; Bosch, Francesc Xavier; de Sanjose, Silvia; Alemany, Laia; CANCER CYTOPATHOLOGY 1934-662X (2020) DOI / 10.1002/cncy.22266
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Article BRCA1 haploinsufficiency cell-autonomously activates RANKL expression and generates denosumab-responsive breast cancer-initiating cells Cuyas, Elisabet; Corominas-Faja, Bruna; Munoz-San Martin, Maria; Martin-Castillo, Begona; Lupu, Ruth; Brunet, Joan; Bosch-Barrera, Joaquim; Menendez, Javier A. ONCOTARGET 1949-2553 (2017) DOI / 10.18632/oncotarget.16558 Green published, Gold other
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Article Opportunistic testing of BRCA1, BRCA2 and mismatch repair genes improves the yield of phenotype driven hereditary cancer gene panels Feliubadalo, Lidia; Lopez-Fernandez, Adria; Pineda, Marta; Diez, Orland; del Valle, Jesus; Gutierrez-Enriquez, Sara; Teule, Alex; Gonzalez, Sara; Stjepanovic, Neda; Salinas, Monica; Capella, Gabriel; Brunet, Joan; Lazaro, Conxi; Balmana, Judith; Campos, Ol INTERNATIONAL JOURNAL OF CANCER 0020-7136 (2019) DOI / 10.1002/ijc.32304
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Article Complete Loss of EPCAM Immunoexpression Identifies EPCAM Deletion Carriers in MSH2-Negative Colorectal Neoplasia Cuatrecasas, Miriam; Gorostiaga, Inigo; Riera, Cristina; Saperas, Esteban; Llort, Gemma; Costa, Irmgard; Matias-Guiu, Xavier; Carrato, Cristina; Navarro, Matilde; Pineda, Marta; Duenas, Nuria; Brunet, Joan; Marco, Vicente; Trias, Isabel; Busteros, Jose Ign CANCERS (2020) DOI / 10.3390/cancers12102803 Gold DOAJ, Green published
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Article ERCC3, a new ovarian cancer susceptibility gene? Stradella, Agostina; del Valle, Jesus; Rofes, Paula; Vargas-Parra, Gardenia; Salinas, Monica; Gonzalez, Sara; Montes, Eva; Lopez-Doriga, Adriana; Gomez, Carolina; de Cid, Rafael; Darder, Esther; Teule, Alex; Solanes, Ares; Munte, Elisabet; Capella, Gabriel EUROPEAN JOURNAL OF CANCER 0959-8049 (2020) DOI / 10.1016/j.ejca.2020.09.023
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Article High Prevalence of Somatic Oncogenic Driver Alterations in Patients With NSCLC and Li-Fraumeni Syndrome Mezquita, Laura; Jove, Maria; Nadal, Ernest; Kfoury, Maria; Moran, Teresa; Ricordel, Charles; Dhooge, Marion; Tlemsani, Camille; Lena, Herve; Teule, Alex; Alvarez, Jose-Valero; Raimbourg, Judith; Hiret, Sandrine; Lacroix, Ludovic; Menendez, Mireia; Saldana JOURNAL OF THORACIC ONCOLOGY 1556-0864 (2020) DOI / 10.1016/j.jtho.2020.03.005
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Article Paired Somatic-Germline Testing of 15 Polyposis and Colorectal Cancer-Predisposing Genes Highlights the Role of APC Mosaicism in de Novo Familial Adenomatous Polyposis Rofes, Paula; Gonzalez, Sara; Navarro, Matilde; Marcos Moreno-Cabrera, Jose; Solanes, Ares; Darder, Esther; Carrasco, Estela; Iglesias, Silvia; Salinas, Monica; Gomez, Carolina; Velasco, Angela; Tuset, Noemi; Varela, Mar; Llort, Gemma; Ramon y Cajal, Teres JOURNAL OF MOLECULAR DIAGNOSTICS 1525-1578 (2021) DOI / 10.1016/j.jmoldx.2021.07.024
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Article The LSD1 inhibitor iadademstat (ORY-1001) targets SOX2-driven breast cancer stem cells: a potential epigenetic therapy in luminal-B and HER2-positive breast cancer subtypes Cuyas, Elisabet; Gumuzio, Juan; Verdura, Sara; Brunet, Joan; Bosch-Barrera, Joaquim; Martin-Castillo, Begona; Alarcon, Tomas; Antonio Encinar, Jose; Martin, Angel G.; Menendez, Javier A. AGING-US 1945-4589 (2020) DOI / 10.18632/aging.102887 Green published
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Article Resveratrol targets PD-L1 glycosylation and dimerization to enhance antitumor T-cell immunity Verdura, Sara; Cuyas, Elisabet; Cortada, Eric; Brunet, Joan; Lopez-Bonet, Eugeni; Martin-Castillo, Begona; Bosch-Barrera, Joaquim; Antonio Encinar, Jose; Menendez, Javier A. AGING-US 1945-4589 (2020) DOI / 10.18632/aging.102646 Green published
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Letter Response to letter entitled: Re: ERCC3 a new ovarian cancer susceptibility gene? Stradella, Agostina; del Valle, Jesus; Brunet, Joan; Lazaro, Conxi EUROPEAN JOURNAL OF CANCER 0959-8049 (2021) DOI / 10.1016/j.ejca.2021.03.015
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Article Comprehensive Constitutional Genetic and Epigenetic Characterization of Lynch-Like Individuals Damaso, Estela; Gonzalez-Acosta, Maribel; Vargas-Parra, Gardenia; Navarro, Matilde; Balmana, Judith; Ramon y Cajal, Teresa; Tuset, Noemi; Thompson, Bryony A.; Marin, Fatima; Fernandez, Anna; Gomez, Carolina; Velasco, Angela; Solanes, Ares; Iglesias, Silvia CANCERS (2020) DOI / 10.3390/cancers12071799 Green published, Gold
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Article Psychological impact of multigene cancer panel testing in patients with a clinical suspicion of hereditary cancer across Spain Esteban, I.; Vilaro, M.; Adrover, E.; Angulo, A.; Carrasco, E.; Gadea, N.; Sanchez, A.; Ocana, T.; Llort, G.; Jover, R.; Cubiella, J.; Servitja, S.; Herraiz, M.; Cid, L.; Martinez, S.; Oruezabal-Moreno, M. J.; Garau, I.; Khorrami, S.; Herreros-de-Tejada, A PSYCHO-ONCOLOGY 1057-9249 (2018) DOI / 10.1002/pon.4686
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Article Improving Genetic Testing in Hereditary Cancer by RNA Analysis Tools to Prioritize Splicing Studies and Challenges in Applying American College of Medical Genetics and Genomics Guidelines Rofes, Paula; Menendez, Mireia; Gonzalez, Sara; Tornero, Eva; Gomez, Carolina; Vargas-Parra, Gardenia; Montes, Eva; Salinas, Monica; Solanes, Ares; Brunet, Joan; Teule, Alex; Capella, Gabriel; Feliubadalo, Lidia; del Valle, Jesus; Pineda, Marta; Lazaro, Co JOURNAL OF MOLECULAR DIAGNOSTICS 1525-1578 (2020) DOI / 10.1016/j.jmoldx.2020.09.007
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Article Assessing Effectiveness of Colonic and Gynecological Risk Reducing Surgery in Lynch Syndrome Individuals Duenas, Nuria; Navarro, Matilde; Teule, Alex; Solanes, Ares; Salinas, Monica; Iglesias, Silvia; Munte, Elisabet; Ponce, Jordi; Guardiola, Jordi; Kreisler, Esther; Carballas, Elvira; Cuadrado, Marta; Matias-Guiu, Xavier; de la Ossa, Napoleon; Lop, Joan; Laz CANCERS (2020) DOI / 10.3390/cancers12113419 Green published, Gold

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