Pharmacology & Toxicology


  Listando 17 trabajos del autor/autora 38
Lista de trabajos en el área Pharmacology & Toxicology
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Article Melatonin Reduces NLRP3 Inflammasome Activation by Increasing alpha 7 nAChR-Mediated Autophagic Flux Farre-Alins, Victor; Narros-Fernandez, Paloma; Palomino-Antolin, Alejandra; Decouty-Perez, Celine; Lopez-Rodriguez, Ana Belen; Parada, Esther; Munoz-Montero, Alicia; Gomez-Rangel, Vanessa; Lopez-Manoz, Francisco; Ramos, Eva; Gonzalez-Rodriguez, Agueda; Gan ANTIOXIDANTS (2020) DOI / 10.3390/antiox9121299 Gold other, Green published
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Article TLR4 pathway impairs synaptic number and cerebrovascular functions through astrocyte activation following traumatic brain injury Rosa, Juliana M.; Farre-Alins, Victor; Ortega, Maria Cristina; Navarrete, Marta; Lopez-Rodriguez, Ana Belen; Palomino-Antolin, Alejandra; Fernandez-Lopez, Elena; Vila-del Sol, Virginia; Decouty, Celine; Narros-Fernandez, Paloma; Clemente, Diego; Egea, Javi BRITISH JOURNAL OF PHARMACOLOGY 0007-1188 (2021) DOI / 10.1111/bph.15488 Hybrid, Green published
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Review The Coronavirus Disease 2019 (COVID-19): Key Emphasis on Melatonin Safety and Therapeutic Efficacy Ramos, Eva; Lopez-Munoz, Francisco; Gil-Martin, Emilio; Egea, Javier; Alvarez-Merz, Iris; Painuli, Sakshi; Semwal, Prabhakar; Martins, Natalia; Hernandez-Guijo, Jesus M.; Romero, Alejandro ANTIOXIDANTS (2021) DOI / 10.3390/antiox10071152 Gold, Green published
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Article Analogues of cannabinoids as multitarget drugs in the treatment of Alzheimer's disease Sanchez Montero, Jose Maria; Agis-Torres, Angel; Solano, David; Sollhuber, Monica; Fernandez, Maria; Villaro, Wilma; Gomez-Canas, Maria; Garcia-Arencibia, Moises; Fernandez-Ruiz, Javier; Egea, Javier; Isabel Martin, Maria; Giron, Rocio EUROPEAN JOURNAL OF PHARMACOLOGY 0014-2999 (2021) DOI / 10.1016/j.ejphar.2021.173875
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Article Synthesis and Pharmacological Evaluation of Novel Non-nucleotide Purine Derivatives as P2X7 Antagonists for the Treatment of Neuroinflammation Calzaferri, Francesco; Narros-Fernandez, Paloma; de Pascual, Ricardo; de Diego, Antonio M. G.; Nicke, Annette; Egea, Javier; Garcia, Antonio G.; de los Rios, Cristobal JOURNAL OF MEDICINAL CHEMISTRY 0022-2623 (2021) DOI / 10.1021/acs.jmedchem.0c02145
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Article Privileged Quinolylnitrones for the Combined Therapy of Ischemic Stroke and Alzheimer's Disease Alonso, Jose M.; Escobar-Peso, Alejandro; Palomino-Antolin, Alejandra; Diez-Iriepa, Daniel; Chioua, Mourad; Martinez-Alonso, Emma; Iriepa, Isabel; Egea, Javier; Alcazar, Alberto; Marco-Contelles, Jose PHARMACEUTICALS (2021) DOI / 10.3390/ph14090861 Gold, Green published
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Article Enzymatic and solid-phase synthesis of new donepezil-based L-and D-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer ' s disease and cerebral ischemia Monjas, Leticia; Arce, Mariana P.; Leon, Rafael; Egea, Javier; Perez, Concepcion; Villarroya, Mercedes; Lopez, Manuela G.; Gil, Carmen; Conde, Santiago; Isabel Rodriguez-Franco, Maria EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 0223-5234 (2017) DOI / 10.1016/j.ejmech.2017.02.034 Green submitted
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Article Nrf2 Plays a Protective Role Against Intravascular Hemolysis-Mediated Acute Kidney Injury Rubio-Navarro, Alfonso; Vazquez-Carballo, Cristina; Guerrero-Hue, Melania; Garcia-Caballero, Cristina; Herencia, Carmen; Gutierrez, Eduardo; Yuste, Claudia; Sevillano, Angel; Praga, Manuel; Egea, Javier; Cannata, Pablo; Cortegano, Isabel; de Andres, Belen; FRONTIERS IN PHARMACOLOGY (2019) DOI / 10.3389/fphar.2019.00740 Green published, Gold
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Article Serum Amyloid A1/Toll-Like Receptor-4 Axis, an Important Link between Inflammation and Outcome of TBI Patients Farre-Alins, Victor; Palomino-Antolin, Alejandra; Narros-Fernandez, Paloma; Lopez-Rodriguez, Ana Belen; Decouty-Perez, Celine; Munoz-Montero, Alicia; Zamorano-Fernandez, Jorge; Mansilla-Fernandez, Beatriz; Giner-Garcia, Javier; Garcia-Feijoo, Pablo; Saez-A BIOMEDICINES (2021) DOI / 10.3390/biomedicines9060599 Gold DOAJ, Green published
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Review The emergence of melatonin in oncology: Focus on colorectal cancer Gil-Martin, Emilio; Egea, Javier; Reiter, Russel J.; Romero, Alejandro MEDICINAL RESEARCH REVIEWS 0198-6325 (2019) DOI / 10.1002/med.21582
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Review Melatonin's efficacy in stroke patients; a matter of dose? A systematic review Ramos, Eva; Farre-Alins, Victor; Egea, Javier; Lopez-Munoz, Francisco; Reiter, Russel J.; Romero, Alejandro TOXICOLOGY AND APPLIED PHARMACOLOGY 0041-008X (2020) DOI / 10.1016/j.taap.2020.114933
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Article In Silico Prediction of the Toxic Potential of Neuroprotective Bifunctional Molecules Based on Chiral N-Propargyl-1,2-amino Alcohol Derivatives Ramos, Eva; Lajarin-Cuesta, Rocio; Arribas, Raquel L.; Garcia-Frutos, Eva M.; Gonzalez-Lafuente, Laura; Egea, Javier; de los Rios, Cristobal; Romero, Alejandro CHEMICAL RESEARCH IN TOXICOLOGY 0893-228X (2021) DOI / 10.1021/acs.chemrestox.0c00519
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Review Targeting Nrf2 in Protection Against Renal Disease Guerrero-Hues, Melania; Farre-Alins, Victor; Palomino-Antolin, Alejandra; Parada, Esther; Rubio-Navarro, Alfonso; Egido, Jesus; Egea, Javier; Moreno, Juan A. CURRENT MEDICINAL CHEMISTRY 0929-8673 (2017) DOI / 10.2174/0929867324666170511120814
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Editorial Material Editorial: Role of Nrf2 in Disease: Novel Molecular Mechanisms and Therapeutic Approaches Egea, Javier; Gonzalez-Rodriguez, Agueda; Gomez-Guerrero, Carmen; Antonio Moreno, Juan FRONTIERS IN PHARMACOLOGY (2019) DOI / 10.3389/fphar.2019.01149 Green published, Gold
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Article Early toll-like receptor 4 blockade reduces ROS and inflammation triggered by microglial pro-inflammatory phenotype in rodent and human brain ischaemia models Parada, Esther; Casas, Ana I.; Palomino-Antolin, Alejandra; Gomez-Rangel, Vanessa; Rubio-Navarro, Alfonso; Farre-Alins, Victor; Narros-Fernandez, Paloma; Guerrero-Hue, Melania; Antonio Moreno, Juan; Rosa, Juliana M.; Roda, Jose M.; Hernandez-Garcia, Borja BRITISH JOURNAL OF PHARMACOLOGY 0007-1188 (2019) DOI / 10.1111/bph.14703 Bronze, Green published
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Review Melatonin as a versatile molecule to design novel multitarget hybrids against neurodegeneration Ramos, Eva; Egea, Javier; de los Rios, Cristobal; Marco-Contelles, Jose; Romero, Alejandro FUTURE MEDICINAL CHEMISTRY 1756-8919 (2017) DOI / 10.4155/fmc-2017-0014
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Article In Vitro and In Silico ADME-Tox Profiling and Safety Significance of Multifunctional Monoamine Oxidase Inhibitors Targeting Neurodegenerative Diseases Wieckowska, Anna; Szalaj, Natalia; Goral, Izabella; Bucki, Adam; Latacz, Gniewomir; Kiec-Kononowicz, Katarzyna; Bautista-Aguilera, Oscar M.; Romero, Alejandro; Ramos, Eva; Egea, Javier; Alins, Victor Farre; Gonzalez-Rodriguez, Agueda; Lopez-Munoz, Francisc ACS CHEMICAL NEUROSCIENCE 1948-7193 (2020) DOI / 10.1021/acschemneuro.0c00489 Green published, Gold other

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