Clinical Medicine

Listando 38 trabajos del autor/autora 38

Lista de trabajos en el área Clinical Medicine

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Article HER2-enriched subtype as a predictor of pathological complete response following trastuzumab and lapatinib without chemotherapy in early-stage HER2-positive breast cancer (PAMELA): an open-label, single-group, multicentre, phase 2 trial Llombart-Cussac, Antonio; Cortes, Javier; Pare, Laia; Galvan, Patricia; Bermejo, Begona; Martinez, Noelia; Vidal, Maria; Pernas, Sonia; Lopez, Rafael; Munoz, Montserrat; Nuciforo, Paolo; Morales, Serafin; Oliveira, Mafalda; de la Pena, Lorena; Pelaez, Alex LANCET ONCOLOGY 1470-2045 (2017) DOI / 10.1016/s1470-2045(17)30021-9

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Article A predictive model of pathologic response based on tumor cellularity and tumor-infiltrating lymphocytes (CelTIL) in HER2-positive breast cancer treated with chemo-free dual HER2 blockade Nuciforo, P.; Pascual, T.; Cortes, J.; Llombart-Cussac, A.; Fasani, R.; Pare, L.; Oliveira, M.; Galvan, P.; Martinez, N.; Bermejo, B.; Vidal, M.; Pernas, S.; Lopez, R.; Munoz, M.; Garau, I.; Manso, L.; Alarcon, J.; Martinez, E.; Rodrik-Outmezguine, V.; Bra ANNALS OF ONCOLOGY 0923-7534 (2018) DOI / 10.1093/annonc/mdx647 Bronze

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Article MONARCH 2: Abemaciclib in Combination With Fulvestrant in Women With HR+/HER2-Advanced Breast Cancer Who Had Progressed While Receiving Endocrine Therapy Sledge, George W., Jr.; Toi, Masakazu; Neven, Patrick; Sohn, Joohyuk; Inoue, Kenichi; Pivot, Xavier; Burdaeva, Olga; Okera, Meena; Masuda, Norikazu; Kaufman, Peter A.; Koh, Han; Grischke, Eva-Maria; Frenzel, Martin; Lin, Yong; Barriga, Susana; Smith, Ian C JOURNAL OF CLINICAL ONCOLOGY 0732-183X (2017) DOI / 10.1200/jco.2017.73.7585

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Article The Effect of Abemaciclib Plus Fulvestrant on Overall Survival in Hormone Receptor-Positive, ERBB2-Negative Breast Cancer That Progressed on Endocrine Therapy-MONARCH 2 A Randomized Clinical Trial Sledge, George W.; Toi, Masakazu; Neven, Patrick; Sohn, Joohyuk; Inoue, Kenichi; Pivot, Xavier; Burdaeva, Olga; Okera, Meena; Masuda, Norikazu; Kaufman, Peter A.; Koh, Han; Grischke, Eva-Maria; Conte, Pierfranco; Lu, Yi; Barriga, Susana; Hurt, Karla; Frenz JAMA ONCOLOGY 2374-2437 (2020) DOI / 10.1001/jamaoncol.2019.4782 Gold other, Green published

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Article Ribociclib plus letrozole versus chemotherapy for postmenopausal women with hormone receptor-positive, HER2-negative, luminal B breast cancer (CORALLEEN): an open-label, multicentre, randomised, phase 2 trial Prat, Aleix; Saura, Cristina; Pascual, Tomas; Hernando, Cristina; Munoz, Montserrat; Pare, Laia; Gonzalez Farre, Blanca; Fernandez, Pedro L.; Galvan, Patricia; Chic, Nuria; Gonzalez Farre, Xavier; Oliveira, Mafalda; Gil-Gil, Miguel; Arumi, Miriam; Ferrer, LANCET ONCOLOGY 1470-2045 (2020) DOI / 10.1016/s1470-2045(19)30786-7

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Article Prognostic characteristics in hormone receptor-positive advanced breast cancer and characterization of abemaciclib efficacy Di Leo, Angelo; O'Shaughnessy, Joyce; Sledge, George W., Jr.; Martin, Miguel; Lin, Yong; Frenzel, Martin; Hardebeck, Molly C.; Smith, Ian C.; Llombart-Cussac, Antonio; Goetz, Matthew P.; Johnston, Stephen NPJ BREAST CANCER (2018) DOI / 10.1038/s41523-018-0094-2 Gold DOAJ, Green published

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Article HER2-Enriched Subtype and ERBB2 Expression in HER2-Positive Breast Cancer Treated with Dual HER2 Blockade Prat, Aleix; Pascual, Tomas; De Angelis, Carmine; Gutierrez, Carolina; Llombart-Cussac, Antonio; Wang, Tao; Cortes, Javier; Rexer, Brent; Pare, Laia; Forero, Andres; Wolff, Antonio C.; Morales, Serafin; Adamo, Barbara; Braso-Maristany, Fara; Vidal, Maria; JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE 0027-8874 (2020) DOI / 10.1093/jnci/djz042 Green published, Bronze

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Article Chemotherapy de-escalation using an F-18-FDG-PET-based pathological response-adapted strategy in patients with HER2-positive early breast cancer (PHERGain): a multicentre, randomised, open-label, non-comparative, phase 2 trial Manuel Perez-Garcia, Jose; Gebhart, Geraldine; Ruiz Borrego, Manuel; Stradella, Agostina; Bermejo, Begona; Schmid, Peter; Marme, Frederik; Escriva-de-Romani, Santiago; Calvo, Lourdes; Ribelles, Nuria; Martinez, Noelia; Albacar, Cinta; Prat, Aleix; Dalenc, LANCET ONCOLOGY 1470-2045 (2021) DOI / 10.1016/s1470-2045(21)00122-4

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Article Survival impact of primary tumor resection in de novo metastatic breast cancer patients (GEICAM/El Alamo Registry) Lopez-Tarruella, Sara; Escudero, M. J.; Pollan, Marina; Martin, Miguel; Jara, Carlos; Bermejo, Begona; Guerrero-Zotano, Angel; Garcia-Saenz, Jose; Santaballa, Ana; Alba, Emilio; Andres, Raquel; Martinez, Purificacion; Calvo, Lourdes; Fernandez, Antonio; Ba SCIENTIFIC REPORTS 2045-2322 (2019) DOI / 10.1038/s41598-019-55765-9 Gold DOAJ, Green published

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Article Phenotypic changes of HER2-positive breast cancer during and after dual HER2 blockade Braso-Maristany, Fara; Griguolo, Gaia; Pascual, Tomas; Pare, Laia; Nuciforo, Paolo; Llombart-Cussac, Antonio; Bermejo, Begona; Oliveira, Mafalda; Morales, Serafin; Martinez, Noelia; Vidal, Maria; Adamo, Barbara; Martinez, Olga; Pernas, Sonia; Lopez, Rafael NATURE COMMUNICATIONS (2020) DOI / 10.1038/s41467-019-14111-3 Gold DOAJ, Green published

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Article F-18-fluoromisonidazole PET and Activity of Neoadjuvant Nintedanib in Early HER2-Negative Breast Cancer: A Window-of-Opportunity Randomized Trial Quintela-Fandino, Miguel; Lluch, Ana; Manso, Luis; Calvo, Isabel; Cortes, Javier; Angel Garcia-Saenz, Jose; Gil-Gil, Miguel; Martinez-Janez, Noelia; Gonzalez-Martin, Antonio; Adrover, Encarna; de Andres, Raquel; Vinas, Gemma; Llombart-Cussac, Antonio; Alba CLINICAL CANCER RESEARCH 1078-0432 (2017) DOI / 10.1158/1078-0432.ccr-16-0738 Bronze

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Article Safety, activity, and molecular heterogeneity following neoadjuvant non-pegylated liposomal doxorubicin, paclitaxel, trastuzumab, and pertuzumab in HER2-positive breast cancer (Opti-HER HEART): an open-label, single-group, multicenter, phase 2 trial Gavila, Joaquin; Oliveira, Mafalda; Pascual, Tomas; Perez-Garcia, Jose; Gonzalez, Xavier; Canes, Jordi; Pare, Laia; Calvo, Isabel; Ciruelos, Eva; Munoz, Montserrat; Virizuela, Juan A.; Ruiz, Isabel; Andres, Raquel; Perello, Antonia; Martinez, Jeronimo; Mor BMC MEDICINE 1741-7015 (2019) DOI / 10.1186/s12916-018-1233-1 Green published, Gold

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Article Neoadjuvant eribulin in HER2-negative early-stage breast cancer (SOLTI-1007-NeoEribulin): a multicenter, two-cohort, non-randomized phase II trial Pascual, Tomas; Oliveira, Mafalda; Villagrasa, Patricia; Ortega, Vanesa; Pare, Laia; Bermejo, Begona; Morales, Serafin; Amillano, Kepa; Lopez, Rafael; Galvan, Patricia; Canes, Jordi; Salvador, Fernando; Nuciforo, Paolo; Rubio, Isabel T.; Llombart-Cussac, A NPJ BREAST CANCER (2021) DOI / 10.1038/s41523-021-00351-4 Gold

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Review Overall Survival of CDK4/6-Inhibitor-Based Treatments in Clinically Relevant Subgroups of Metastatic Breast Cancer: Systematic Review and Meta-Analysis Schettini, Francesco; Giudici, Fabiola; Giuliano, Mario; Cristofanilli, Massimo; Arpino, Grazia; Del Mastro, Lucia; Puglisi, Fabio; De Placido, Sabino; Paris, Ida; De Placido, Pietro; Venturini, Sergio; de Laurentis, Michelino; Conte, Pierfranco; Juric, De JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE 0027-8874 (2020) DOI / 10.1093/jnci/djaa071 Green published

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Article Immune microenvironment characterisation and dynamics during anti-HER2-based neoadjuvant treatment in HER2-positive breast cancer Griguolo, G.; Serna, G.; Pascual, T.; Fasani, R.; Guardia, X.; Chic, N.; Pare, L.; Pernas, S.; Munoz, M.; Oliveira, M.; Vidal, M.; Llombart-Cussac, A.; Cortes, J.; Galvan, P.; Bermejo, B.; Martinez, N.; Lopez, R.; Morales, S.; Garau, I; Manso, L.; Alarcon, NPJ PRECISION ONCOLOGY (2021) DOI / 10.1038/s41698-021-00163-6 Gold DOAJ

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Article Enhancing global access to cancer medicines Cortes, Javier; Perez-Garcia, Jose Manuel; Llombart-Cussac, Antonio; Curigliano, Giuseppe; El Saghir, Nagi S.; Cardoso, Fatima; Barrios, Carlos H.; Wagle, Shama; Roman, Javier; Harbeck, Nadia; Eniu, Alexandru; Kaufman, Peter A.; Tabernero, Josep; Garcia-Es CA-A CANCER JOURNAL FOR CLINICIANS 0007-9235 (2020) DOI / 10.3322/caac.21597 Gold

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Article Palbociclib combined with endocrine therapy in heavily pretreated HR+/HER2(-) advanced breast cancer patients: Results from the compassionate use program in Spain (PALBOCOMP) Manso, Luis; Hernando, Cristina; Galan, Maria; Oliveira, Mafalda; Cabrera, Miguel A.; Bratos, Raquel; Rodriguez, Cesar A.; Ruiz-Borrego, Manuel; Blanch, Salvador; Llombart-Cussac, Antonio; Delgado-Mingorance, Juan I.; Alvarez-Busto, Inaki; Gallegos, Isabel BREAST 0960-9776 (2020) DOI / 10.1016/j.breast.2020.11.005 Gold DOAJ, Green published

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Editorial Material CDK4/6 inhibitors in breast cancer: spotting the difference Perez-Garcia, Jose Manuel; Cortes, Javier; Llombart-Cussac, Antonio NATURE MEDICINE 1078-8956 (2021) DOI / 10.1038/s41591-021-01570-9

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Article ER+ Breast Cancers Resistant to Prolonged Neoadjuvant Letrozole Exhibit an E2F4 Transcriptional Program Sensitive to CDK4/6 Inhibitors Guerrero-Zotano, Angel L.; Stricker, Thomas P.; Formisano, Luigi; Hutchinson, Katherine E.; Stover, Daniel G.; Lee, Kyung-min; Schwarz, Luis J.; Giltnane, Jennifer M.; Estrada, Monica V.; Jansen, Valerie M.; Servetto, Alberto; Gavila, Joaquin; Perez-Fidalg CLINICAL CANCER RESEARCH 1078-0432 (2018) DOI / 10.1158/1078-0432.ccr-17-2904 Bronze, Green accepted

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Article A retrospective, multicenter study of the efficacy of lapatinib plus trastuzumab in HER2-positive metastatic breast cancer patients previously treated with trastuzumab, lapatinib, or both: the Trastyvere study Gavila, J.; de la Haba, J.; Bermejo, B.; Rodriguez-Lescure, A.; Anton, A.; Ciruelos, E.; Brunet, J.; Munoz-Couselo, E.; Santisteban, M.; Rodriguez Sanchez, C. A.; Santaballa, A.; Sanchez Rovira, P.; Garcia Saenz, J. A.; Ruiz-Borrego, M.; Guerrero-Zotano, A CLINICAL & TRANSLATIONAL ONCOLOGY 1699-048X (2020) DOI / 10.1007/s12094-019-02145-4

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Article Pembrolizumab plus eribulin in hormone receptore-positive, HER2-negative, locally recurrent or metastatic breast cancer (KELLY): An open-label, multicentre, single-arm, phase II trial Perez-Garcia, Jose M.; Llombart-Cussac, Antonio; Cortes, Maria G.; Curigliano, Giuseppe; Lopez-Miranda, Elena; Alonso, Jose L.; Bermejo, Begona; Calvo, Lourdes; Caranana, Vicente; de la Cruz Sanchez, Susana; Vazquez, Raul M.; Prat, Aleix; Borrego, Manuel R EUROPEAN JOURNAL OF CANCER 0959-8049 (2021) DOI / 10.1016/j.ejca.2021.02.028

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Article Immune checkpoint inhibitors: a physiology-driven approach to the treatment of coronavirus disease 2019 Di Cosimo, Serena; Malfettone, Andrea; Perez-Garcia, Jose M.; Llombart-Cussac, Antonio; Miceli, Rosalba; Curigliano, Giuseppe; Cortes, Javier EUROPEAN JOURNAL OF CANCER 0959-8049 (2020) DOI / 10.1016/j.ejca.2020.05.026 Bronze, Green published

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Review Surrogate endpoints for early-stage breast cancer: a review of the state of the art, controversies, and future prospects Gion, Maria; Manuel Perez-Garcia, Jose; Llombart-Cussac, Antonio; Sampayo-Cordero, Miguel; Cortes, Javier; Malfettone, Andrea THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY 1758-8340 (2021) DOI / 10.1177/17588359211059587 Green published, Gold

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Article Phase II, Multicenter, Single-arm Trial of Eribulin as First-line Therapy for Patients With Aggressive Taxane-pretreated HER2-Negative Metastatic Breast Cancer: The MERIBEL Study Ortega, Vanesa; Anton, Antonio; Garau, Isabel; Afonso, Nomia; Calvo, Lourdes; Fernandez, Yolanda; Martinez-Garcia, Maria; Blanco, Esperanza; Zamora, Pilar; Garcia, Mirta; Juan Illarramendi, Jose; Rodriguez Sanchez, Csar Augusto; Sampayo, Miguel; Aguirre, E CLINICAL BREAST CANCER 1526-8209 (2019) DOI / 10.1016/j.clbc.2018.12.012

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Review Preclinical and clinical development of palbociclib and future perspectives Martinez De Duenas, E.; Gavila-Gregori, J.; Olmos-Anton, S.; Santaballa-Bertran, A.; Lluch-Hernandez, A.; Espinal-Dominguez, E. J.; Rivero-Silva, M.; Llombart-Cussac, A. CLINICAL & TRANSLATIONAL ONCOLOGY 1699-048X (2018) DOI / 10.1007/s12094-018-1850-3

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Article Critically short telomeres and toxicity of chemotherapy in early breast cancer Quintela-Fandino, Miguel; Soberon, Nora; Lluch, Ana; Manso, Luis; Calvo, Isabel; Cortes, Javier; Moreno-Anton, Fernando; Gil-Gil, Miguel; Martinez-Janez, Noelia; Gonzalez-Martin, Antonio; Adrover, Encarna; de Andres, Raquel; Vinas, Gemma; Llombart-Cussac, ONCOTARGET 1949-2553 (2017) DOI / 10.18632/oncotarget.15592 Green submitted, Green published, Gold

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Article PI3K activation promotes resistance to eribulin in HER2-negative breast cancer Gris-Oliver, Albert; Ibrahim, Yasir H.; Rivas, Martin A.; Garcia-Garcia, Celina; Sanchez-Guixe, Monica; Ruiz-Pace, Fiorella; Viaplana, Cristina; Perez-Garcia, Jose M.; Llombart-Cussac, Antonio; Grueso, Judit; Pares, Mireia; Guzman, Marta; Rodriguez, Olga; BRITISH JOURNAL OF CANCER 0007-0920 (2021) DOI / 10.1038/s41416-021-01293-1

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Article Poly(adenosine diphosphate ribose) polymerase inhibitors induce autophagy-mediated drug resistance in ovarian cancer cells, xenografts, and patient-derived xenograft models Santiago-O'Farrill, Janice M.; Weroha, S. John; Hou, Xiaonan; Oberg, Ann L.; Heinzen, Ethan P.; Maurer, Matthew J.; Pang, Lan; Rask, Philip; Amaravadi, Ravi K.; Becker, Sarah E.; Romero, Ignacio; Jesus Rubio, Ma; Matias-Guiu, Xavier; Santacana, Maria; Llom CANCER 0008-543X (2019) DOI / 10.1002/cncr.32600

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Article Nobody dares stopping clinical research, not even COVID-19 Malfettone, Andrea; Di Cosimo, Serena; Perez-Garcia, Jose Manuel; Garcia, Alicia; Sampayo-Cordero, Miguel; Mina, Leonardo; Herrero, Carolina; Llombart-Cussac, Antonio; Cortes, Javier NPJ BREAST CANCER (2021) DOI / 10.1038/s41523-021-00249-1 Gold DOAJ, Green published

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Review Soluble Biomarkers with Prognostic and Predictive Value in Advanced Non-Small Cell Lung Cancer Treated with Immunotherapy Honrubia-Peris, Beatriz; Garde-Noguera, Javier; Garcia-Sanchez, Jose; Piera-Molons, Nuria; Llombart-Cussac, Antonio; Fernandez-Murga, Maria Leonor CANCERS (2021) DOI / 10.3390/cancers13174280 Green published, Gold

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Article MONARCH 2: Subgroup Analysis of Patients Receiving Abemaciclib Plus Fulvestrant as First-Line and Second-Line Therapy for HR+, HER2(-)-Advanced Breast Cancer Neven, Patrick; Johnston, Stephen R. D.; Toi, Masakazu; Sohn, Joohyuk; Inoue, Kenichi; Pivot, Xavier; Burdaeva, Olga; Okera, Meena; Masuda, Norikazu; Kaufman, Peter A.; Koh, Han; Grischke, Eva-Maria; Conte, Pierfranco; Lu, Yi; Haddad, Nadine; Hurt, Karla C CLINICAL CANCER RESEARCH 1078-0432 (2021) DOI / 10.1158/1078-0432.ccr-20-4685