Molecular Biology & Genetics


  Listando 29 trabajos del autor/autora 38
Lista de trabajos en el área Molecular Biology & Genetics
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Review Carbotoxicity-Noxious Effects of Carbohydrates Kroemer, Guido; Lopez-Otin, Carlos; Madeo, Frank; de Cabo, Rafael CELL 0092-8674 (2018) DOI / 10.1016/j.cell.2018.07.044 Bronze, Green accepted
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Article Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice Barcena, Clea; Valdes-Mas, Rafael; Mayoral, Pablo; Garabaya, Cecilia; Durand, Sylvere; Rodriguez, Francisco; Teresa Fernandez-Garcia, Maria; Salazar, Nuria; Nogacka, Alicja M.; Garatachea, Nuria; Bossut, Noelie; Aprahamian, Fanny; Lucia, Alejandro; Kroemer NATURE MEDICINE 1078-8956 (2019) DOI / 10.1038/s41591-019-0504-5
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Review Hallmarks of Health Lopez-Otin, Carlos; Kroemer, Guido CELL 0092-8674 (2021) DOI / 10.1016/j.cell.2020.11.034
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Article Changes at the nuclear lamina alter binding of pioneer factor Foxa2 in aged liver Whitton, Holly; Singh, Larry N.; Patrick, Marissa A.; Price, Andrew J.; Osorio, Fernando G.; Lopez-Otin, Carlos; Bochkis, Irina M. AGING CELL 1474-9718 (2018) DOI / 10.1111/acel.12742 Gold DOAJ, Green published
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Article The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia Beekman, Renee; Chapaprieta, Vicente; Russinol, Nuria; Vilarrasa-Blasi, Roser; Verdaguer-Dot, Nuria; Martens, Joost H. A.; Duran-Ferrer, Marti; Kulis, Marta; Serra, Francois; Javierre, Biola M.; Wingett, Steven W.; Clot, Guillem; Queiros, Ana C.; Castellan NATURE MEDICINE 1078-8956 (2018) DOI / 10.1038/s41591-018-0028-4 Green accepted
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Article Development of a CRISPR/Cas9-based therapy for Hutchinson-Gilford progeria syndrome Santiago-Fernandez, Olaya; Osorio, Fernando G.; Quesada, Victor; Rodriguez, Francisco; Basso, Sammy; Maeso, Daniel; Rolas, Loic; Barkaway, Anna; Nourshargh, Sussan; Folgueras, Alicia R.; Freije, Jose M. P.; Lopez-Otin, Carlos NATURE MEDICINE 1078-8956 (2019) DOI / 10.1038/s41591-018-0338-6 Green accepted
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Article Precise in vivo genome editing via single homology arm donor mediated intron-targeting gene integration for genetic disease correction Suzuki, Keiichiro; Yamamoto, Mako; Hernandez-Benitez, Reyna; Li, Zhe; Wei, Christopher; Devi Soligalla, Rupa; Aizawa, Emi; Hatanaka, Fumiyuki; Kurita, Masakazu; Reddy, Pradeep; Ocampo, Alejandro; Hishida, Tomoaki; Sakurai, Masahiro; Nemeth, Amy N.; Nunez D CELL RESEARCH 1001-0602 (2019) DOI / 10.1038/s41422-019-0213-0 Green published, Bronze
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Article A single-copy Sleeping Beauty transposon mutagenesis screen identifies new PTEN-cooperating tumor suppressor genes de la Rosa, Jorge; Weber, Julia; Friedrich, Mathias Josef; Li, Yilong; Rad, Lena; Ponstingl, Hannes; Liang, Qi; de Quiros, Sandra Bernaldo; Noorani, Imran; Metzakopian, Emmanouil; Strong, Alexander; Li, Meng Amy; Astudillo, Aurora; Fernadez-Garcia, Mara Te NATURE GENETICS 1061-4036 (2017) DOI / 10.1038/ng.3817 Green accepted
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Article Insight into genetic predisposition to chronic lymphocytic leukemia from integrative epigenomics Speedy, Helen E.; Beekman, Renee; Chapaprieta, Vicente; Orlando, Giulia; Law, Philip J.; Martin-Garcia, David; Gutierrez-Abril, Jesus; Catovsky, Daniel; Bea, Silvia; Clot, Guillem; Puiggros, Montserrat; Torrents, David; Puente, Xose S.; Allan, James M.; Lo NATURE COMMUNICATIONS (2019) DOI / 10.1038/s41467-019-11582-2 Gold DOAJ, Green published
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Article Remodeling of Bone Marrow Hematopoietic Stem Cell Niches Promotes Myeloid Cell Expansion during Premature or Physiological Aging Ho, Ya-Hsuan; Del Toro, Raquel; Rivera-Torres, Jose; Rak, Justyna; Korn, Claudia; Garcia-Garcia, Andres; Macias, David; Gonzalez-Gomez, Cristina; del Monte, Alberto; Wittner, Monika; Waller, Amie K.; Foster, Holly R.; Lopez-Otin, Carlos; Johnson, Randall S CELL STEM CELL 1934-5909 (2019) DOI / 10.1016/j.stem.2019.06.007 Hybrid, Green published
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Article Ablation of the stress protease OMA1 protects against heart failure in mice Acin-Perez, Rebeca; Victoria Lechuga-Vieco, Ana; del Mar Munoz, Maria; Nieto-Arellano, Rocio; Torroja, Carlos; Sanchez-Cabo, Fatima; Jimenez, Concepcion; Gonzalez-Guerra, Andres; Carrascoso, Isabel; Beninca, Cristiane; Quiros, Pedro M.; Lopez-Otin, Carlos; SCIENCE TRANSLATIONAL MEDICINE 1946-6234 (2018) DOI / 10.1126/scitranslmed.aan4935
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Review Clonal evolution in leukemia Ferrando, Adolfo A.; Lopez-Otin, Carlos NATURE MEDICINE 1078-8956 (2017) DOI / 10.1038/nm.4410
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Article Methionine Restriction Extends Lifespan in Progeroid Mice and Alters Lipid and Bile Acid Metabolism Barcena, Clea; Quiros, Pedro M.; Durand, Sylvere; Mayoral, Pablo; Rodriguez, Francisco; Caravia, Xurde M.; Marino, Guillermo; Garabaya, Cecilia; Teresa Fernandez-Garcia, Maria; Kroemer, Guido; Freije, Jose M. P.; Lopez-Otin, Carlos CELL REPORTS 2211-1247 (2018) DOI / 10.1016/j.celrep.2018.07.089 Gold, Green published
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Editorial Material Decelerating ageing and biological clocks by autophagy Lopez-Otin, Carlos; Kroemer, Guido NATURE REVIEWS MOLECULAR CELL BIOLOGY 1471-0072 (2019) DOI / 10.1038/s41580-019-0149-8
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Article Immunosuppression by Mutated Calreticulin Released from Malignant Cells Liu, Peng; Zhao, Liwei; Loos, Friedemann; Marty, Caroline; Xie, Wei; Martins, Isabelle; Lachkar, Sylvie; Qu, Bo; Waeckel-Enee, Emmanuelle; Plo, Isabelle; Vainchenker, William; Perez, Franck; Rodriguez, David; Lopez-Otin, Carlos; van Endert, Peter; Zitvogel MOLECULAR CELL 1097-2765 (2020) DOI / 10.1016/j.molcel.2019.11.004
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Article The Novel Evolution of the Sperm Whale Genome Warren, Wesley C.; Kuderna, Lukas; Alexander, Alana; Catchen, Julian; Perez-Silva, Jose G.; Lopez-Otin, Carlos; Quesada, Victor; Minx, Patrick; Tomlinson, Chad; Montague, Michael J.; Farias, Fabiana H. G.; Walter, Ronald B.; Marques-Bonet, Tomas; Glenn, Tr GENOME BIOLOGY AND EVOLUTION 1759-6653 (2017) DOI / 10.1093/gbe/evx187 Gold DOAJ, Green published
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Article Identification of common cardiometabolic alterations and deregulated pathways in mouse and pig models of aging Fanjul, Victor; Jorge, Inmaculada; Camafeita, Emilio; Macias, Alvaro; Gonzalez-Gomez, Cristina; Barettino, Ana; Dorado, Beatriz; Jesus Andres-Manzano, Maria; Rivera-Torres, Jose; Vazquez, Jesus; Lopez-Otin, Carlos; Andres, Vicente AGING CELL 1474-9718 (2020) DOI / 10.1111/acel.13203 Gold DOAJ, Green published
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Article ATG4D is the main ATG8 delipidating enzyme in mammalian cells and protects against cerebellar neurodegeneration Tamargo-Gomez, Isaac; Martinez-Garcia, Gemma G.; Suarez, Maria F.; Rey, Veronica; Fueyo, Antonio; Codina-Martinez, Helena; Bretones, Gabriel; Caravia, Xurde M.; Morel, Etienne; Dupont, Nicolas; Cabo, Roberto; Tomas-Zapico, Cristina; Souquere, Sylvie; Pierr CELL DEATH AND DIFFERENTIATION 1350-9047 (2021) DOI / 10.1038/s41418-021-00776-1 Green published, Hybrid
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Editorial Material Methionine restriction for improving progeria: another autophagy-inducing anti-aging strategy? Barcena, Clea; Lopez-Otin, Carlos; Kroemer, Guido AUTOPHAGY 1554-8627 (2019) DOI / 10.1080/15548627.2018.1533059 Bronze, Green published
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Article Overview of transcriptomic analysis of all human proteases, non-proteolytic homologs and inhibitors: Organ, tissue and ovarian cancer cell line expression profiling of the human protease degradome by the CLIP-CHIP (TM) DNA microarray Kappelhoff, Reinhild; Puente, Xose S.; Wilson, Claire H.; Seth, Arun; Lopez-Otin, Carlos; Overall, Christopher M. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 0167-4889 (2017) DOI / 10.1016/j.bbamcr.2017.08.004 Gold other
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Article The role of matrix metalloproteinases in aging: Tissue remodeling and beyond Freitas-Rodriguez, Sandra; Folgueras, Alicia R.; Lopez-Otin, Carlos BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 0167-4889 (2017) DOI / 10.1016/j.bbamcr.2017.05.007 Bronze
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Article Specific combinations of biallelic POLR3A variants cause Wiedemann-Rautenstrauch syndrome Paolacci, Stefano; Li, Yun; Agolini, Emanuele; Bellacchio, Emanuele; Arboleda-Bustos, Carlos E.; Carrero, Dido; Bertola, Debora; Al-Gazali, Lihadh; Alders, Mariel; Altmueller, Janine; Arboleda, Gonzalo; Beleggia, Filippo; Bruselles, Alessandro; Ciolfi, And JOURNAL OF MEDICAL GENETICS 0022-2593 (2018) DOI / 10.1136/jmedgenet-2018-105528
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Review Tagged ATG8-Coding Constructs for the In Vitro and In Vivo Assessment of ATG4 Activity Lopez-Otin, C.; Marino, G. MOLECULAR CHARACTERIZATION OF AUTOPHAGIC RESPONSES, PT A 0076-6879 (2017) DOI / 10.1016/bs.mie.2016.11.001
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Article Autophagy couteracts weight gain, lipotoxicity and pancreatic beta-cell death upon hypercaloric pro-diabetic regimens Fernandez, Alvaro F.; Barcena, Clea; Martinez-Garcia, Gemma G.; Tamargo-Gomez, Isaac; Suarez, Mariz F.; Pietrocola, Federico; Castoldi, Francesca; Esteban, Lorena; Sierra-Filardi, Elena; Boya, Patricia; Lopez-Otin, Carlos; Kroemer, Guido; Marino, Guillermo CELL DEATH & DISEASE 2041-4889 (2017) DOI / 10.1038/cddis.2017.373 Gold DOAJ, Green published
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Review Functional relevance of miRNAs in premature ageing Caravia, Xurde M.; Roiz-Valle, David; Moran-Alvarez, Alba; Lopez-Otin, Carlos MECHANISMS OF AGEING AND DEVELOPMENT 0047-6374 (2017) DOI / 10.1016/j.mad.2017.05.003 Green submitted
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Article Mitochondrial LonP1 protects cardiomyocytes from ischemia/reperfusion injury in vivo Venkatesh, Sundararajan; Li, Min; Saito, Toshiro; Tong, Mingming; Rashed, Eman; Mareedu, Satvik; Zhai, Peiyong; Barcena, Clea; Lopez-Otin, Carlos; Yehia, Ghassan; Sadoshima, Junichi; Suzuki, Carolyn K. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 0022-2828 (2019) DOI / 10.1016/j.yjmcc.2018.12.017 Green accepted
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Article Immune and inflammatory responses to DNA damage in cancer and aging Soria-Valles, Clara; Lopez-Soto, Alejandro; Osorio, Fernando G.; Lopez-Otin, Carlos MECHANISMS OF AGEING AND DEVELOPMENT 0047-6374 (2017) DOI / 10.1016/j.mad.2016.10.004
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Article Loss of mitochondrial ClpP, Lonp1, and Tfam triggers transcriptional induction of Rnf213, a susceptibility factor for moyamoya disease Key, Jana; Maletzko, Antonia; Kohli, Aneesha; Gispert, Suzana; Torres-Odio, Sylvia; Wittig, Ilka; Heidler, Juliana; Barcena, Clea; Lopez-Otin, Carlos; Lei, Yuanjiu; West, A. Phillip; Muench, Christian; Auburger, Georg NEUROGENETICS 1364-6745 (2020) DOI / 10.1007/s10048-020-00609-2 Gold other, Green published
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Editorial Material A fruitful liaison of ZSCAN10 and ROS on the road to rejuvenation Barcena, Clea; Lopez-Otin, Carlos NATURE CELL BIOLOGY 1465-7392 (2017) DOI / 10.1038/ncb3602

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