Pharmacology & Toxicology
Listando 14 trabajos del autor/autora 38
Lista de trabajos en el área Pharmacology & Toxicology
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14
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10
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Article
Pharmacological Inhibition of Soluble Epoxide Hydrolase as a New Therapy for Alzheimer's Disease
Grinan-Ferre, Christian; Codony, Sandra; Pujol, Eugenia; Yang, Jun; Leiva, Rosana; Escolano, Carmen; Puigoriol-Illamola, Dolors; Companys-Alemany, Julia; Corpas, Ruben; Sanfeliu, Coral; Perez, Belen; Isabel Loza, M.; Brea, Jose; Morisseau, Christophe; Hamm
NEUROTHERAPEUTICS
1933-7213 (2020)
DOI /
10.1007/s13311-020-00854-1
Green accepted, Bronze, Green published, Green submitted
Mentions
20
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0
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10
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0
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Article
Benzofuranyl-2-imidazoles as imidazoline I-2 receptor ligands for Alzheimer's disease
Rodriguez-Arevalo, Sergio; Bagan, Andrea; Grinan-Ferre, Christian; Vasilopoulou, Foteini; Pallas, Merce; Brocos-Mosquera, Iria; Callado, Luis F.; Isabel Loza, M.; Martinez, Anton L.; Brea, Jose; Perez, Belen; Molins, Elies; De Jonghe, Steven; Daelemans, Di
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
0223-5234 (2021)
DOI /
10.1016/j.ejmech.2021.113540
Mentions
65
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8
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Article
Bicyclic alpha-Iminophosphonates as High Affinity Imidazoline I-2 Receptor Ligands for Alzheimer's Disease
Abas, Sonia; Rodriguez-Arevalo, Sergio; Bagan, Andrea; Grinan-Ferre, Christian; Vasilopoulou, Foteini; Brocos-Mosquera, Iria; Muguruza, Carolina; Perez, Belen; Molins, Elies; Javier Luque, F.; Perez-Lozano, Pilar; De Jonghe, Steven; Daelemans, Dirk; Naesen
JOURNAL OF MEDICINAL CHEMISTRY
0022-2623 (2020)
DOI /
10.1021/acs.jmedchem.9b02080
Green accepted, Green submitted
Mentions
12
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10
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Article
Disease-modifying treatment with I-2 imidazoline receptor ligand LSL60101 in an Alzheimer's disease mouse model: a comparative study with donepezil
Vasilopoulou, Foteini; Rodriguez-Arevalo, Sergio; Bagan, Andrea; Escolano, Carmen; Grinan-Ferre, Christian; Pallas, Merce
BRITISH JOURNAL OF PHARMACOLOGY
0007-1188 (2021)
DOI /
10.1111/bph.15478
Green submitted
Mentions
36
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1
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Article
Centrally Active Multitarget Anti-Alzheimer Agents Derived from the Antioxidant Lead CR-6
Javier Perez-Areales, F.; Garrido, Maria; Aso, Ester; Bartolini, Manuela; De Simone, Angela; Espargaro, Alba; Ginex, Tiziana; Sabate, Raimon; Perez, Belen; Andrisano, Vincenza; Puigoriol-Illamola, Dolors; Pallas, Merce; Javier Luque, F.; Isabel Loza, Maria
JOURNAL OF MEDICINAL CHEMISTRY
0022-2623 (2020)
DOI /
10.1021/acs.jmedchem.0c00528
Mentions
4
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1
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Article
Behavioral and Cognitive Improvement Induced by Novel Imidazoline I-2 Receptor Ligands in Female SAMP8 Mice
Grinan-Ferre, Christian; Vasilopoulou, Foteini; Abas, Sonia; Rodriguez-Arevalo, Sergio; Bagan, Andrea; Sureda, Francesc X.; Perez, Belen; Callado, Luis F.; Garcia-Sevilla, Jesus A.; Julia Garcia-Fuster, M.; Escolano, Carmen; Pallas, Merce
NEUROTHERAPEUTICS
1933-7213 (2019)
DOI /
10.1007/s13311-018-00681-5
Bronze, Green published, Green accepted
Mentions
26
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Article
From the Design to the In Vivo Evaluation of Benzohomoadamantane-Derived Soluble Epoxide Hydrolase Inhibitors for the Treatment of Acute Pancreatitis
Codony, Sandra; Calvo-Tusell, Carla; Valverde, Elena; Osuna, Silvia; Morisseau, Christophe; Isabel Loza, M.; Brea, Jose; Perez, Concepcion; Isabel Rodriguez-Franco, Maria; Pizarro-Delgado, Javier; Corpas, Ruben; Grinan-Ferre, Christian; Pallas, Merce; Sanf
JOURNAL OF MEDICINAL CHEMISTRY
0022-2623 (2021)
DOI /
10.1021/acs.jmedchem.0c01601
Mentions
8
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1
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Article
Inhibition of 11 beta-HSD1 Ameliorates Cognition and Molecular Detrimental Changes after Chronic Mild Stress in SAMP8 Mice
Puigoriol-Illamola, Dolors; Companys-Alemany, Julia; McGuire, Kris; Homer, Natalie Z. M.; Leiva, Rosana; Vazquez, Santiago; Mole, Damian J.; Grinan-Ferre, Christian; Pallas, Merce
PHARMACEUTICALS
(2021)
DOI /
10.3390/ph14101040
Green published, Gold
Mentions
19
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Article
From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects
Pont, Caterina; Ginex, Tiziana; Grinan-Ferre, Christian; Scheiner, Matthias; Mattellone, Alexia; Martinez, Noemi; Arce, Elsa M.; Soriano-Fernandez, Yolanda; Naldi, Marina; De Simone, Angela; Barenys, Marta; Gomez-Catalan, Jesus; Perez, Belen; Sabate, Raimo
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
0223-5234 (2021)
DOI /
10.1016/j.ejmech.2021.113779
Hybrid
Mentions
2
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1
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Article
A Novel NMDA Receptor Antagonist Protects against Cognitive Decline Presented by Senescent Mice
Companys-Alemany, Julia; Turcu, Andreea L.; Bellver-Sanchis, Aina; Loza, Maria, I; Brea, Jose M.; Canudas, Anna M.; Leiva, Rosana; Vazquez, Santiago; Pallas, Merce; Grinan-Ferre, Christian
PHARMACEUTICS
(2020)
DOI /
10.3390/pharmaceutics12030284
Green published, Gold
Mentions
1
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1
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Article
Resveratrol Differently Modulates Group I Metabotropic Glutamate Receptors Depending on Age in SAMP8 Mice
Sanchez-Melgar, Alejandro; Luis Albasanz, Jose; Pallas, Merce; Martin, Mairena
ACS CHEMICAL NEUROSCIENCE
1948-7193 (2020)
DOI /
10.1021/acschemneuro.0c00067
Mentions
5
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0
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0
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Article
Amelioration of BPSD-Like Phenotype and Cognitive Decline in SAMP8 Mice Model Accompanied by Molecular Changes after Treatment with I-2-Imidazoline Receptor Ligand MCR5
Vasilopoulou, Foteini; Bagan, Andrea; Rodriguez-Arevalo, Sergio; Escolano, Carmen; Grinan-Ferre, Christian; Pallas, Merce
PHARMACEUTICS
(2020)
DOI /
10.3390/pharmaceutics12050475
Green published, Gold
Mentions
2
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0
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Review
Experimental Models for Aging and their Potential for Novel Drug Discovery
Folch, Jaume; Busquets, Oriol; Ettcheto, Miren; Sanchez-Lopez, Elena; Pallas, Merce; Beas-Zarate, Carlos; Marin, Miguel; Casadesus, Gemma; Olloquequi, Jordi; Auladell, Carme; Camins, Antoni
CURRENT NEUROPHARMACOLOGY
1570-159X (2018)
DOI /
10.2174/1570159x15666170707155345
Green submitted, Green published
Mentions
1
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0
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0
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Article
Design, synthesis and in vivo study of novel pyrrolidine-based 11 beta-HSD1 inhibitors for age-related cognitive dysfunction
Leiva, Rosana; Grinan-Ferre, Christian; Seira, Constanti; Valverde, Elena; McBride, Andrew; Binnie, Margaret; Perez, Belen; Javier Luque, F.; Pallas, Merce; Bidon-Chanal, Axel; Webster, Scott P.; Vazquez, Santiago
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
0223-5234 (2017)
DOI /
10.1016/j.ejmech.2017.08.003
Green submitted
