Pharmacology & Toxicology
Listando 6 trabajos del autor/autora 37
Lista de trabajos en el área Pharmacology & Toxicology
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36
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11
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Article
A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance
O'Neill, Paul M.; Amewu, Richard K.; Charman, Susan A.; Sabbani, Sunil; Gnadig, Nina F.; Straimer, Judith; Fidock, David A.; Shore, Emma R.; Roberts, Natalie L.; Wong, Michael H. -L.; Hong, W. David; Pidathala, Chandrakala; Riley, Chris; Murphy, Ben; Aljay
NATURE COMMUNICATIONS
(2017)
DOI /
10.1038/ncomms15159
Gold DOAJ, Green accepted, Green published
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4
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0
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5
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Article
UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria
Brunschwig, Christel; Lawrence, Nina; Taylor, Dale; Abay, Efrem; Njoroge, Mathew; Basarab, Gregory S.; Le Manach, Claire; Paquet, Tanya; Cabrera, Diego Gonzalez; Nchinda, Aloysius T.; de Kock, Carmen; Wiesner, Lubbe; Denti, Paolo; Waterson, David; Blasco,
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
0066-4804 (2018)
DOI /
10.1128/aac.00012-18
Green published, Green accepted, Bronze
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3
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Article
Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series
Palmer, Michael J.; Deng, Xiaoyi; Watts, Shawn; Krilov, Goran; Gerasyuto, Aleksey; Kokkonda, Sreekanth; El Mazouni, Farah; White, John; White, Karen L.; Striepen, Josefine; Bath, Jade; Schindler, Kyra A.; Yeo, Tomas; Shackleford, David M.; Mok, Sachel; Den
JOURNAL OF MEDICINAL CHEMISTRY
0022-2623 (2021)
DOI /
10.1021/acs.jmedchem.1c00173
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1
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Identification of Fast-Acting 2,6-Disithstituted Imidazopyridines That Are Efficacious in the in Vivo Humanized Plasmodium falciparum NODscidIL2R gamma(null) Mouse Model of Malaria
Nchinda, Aloysius T.; Le Manach, Claire; Paquet, Tanya; Cabrera, Diego Gonzalez; Wicht, Kathryn J.; Brunschwig, Christel; Njoroge, Mathew; Abay, Efrem; Taylor, Dale; Lawrence, Nina; Wittlin, Sergio; Jimenez-Diaz, Maria-Belen; Santos Martinez, Maria; Ferrer
JOURNAL OF MEDICINAL CHEMISTRY
0022-2623 (2018)
DOI /
10.1021/acs.jmedchem.8b00382
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2
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Lead Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series for the Treatment of Malaria
Kokkonda, Sreekanth; Deng, Xiaoyi; White, Karen L.; El Mazouni, Farah; White, John; Shackleford, David M.; Katneni, Kasiram; Chiu, Francis C. K.; Barker, Helena; McLaren, Jenna; Crighton, Elly; Chen, Gong; Angulo-Barturen, Inigo; Jimenez-Diaz, Maria Belen;
JOURNAL OF MEDICINAL CHEMISTRY
0022-2623 (2020)
DOI /
10.1021/acs.jmedchem.0c00311
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1
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A novel class of fast-acting antimalarial agents: Substituted 15-membered azalides
Peric, Mihaela; Pesic, Dijana; Alihodzic, Sulejman; Fajdetic, Andrea; Herreros, Esperanza; Gamo, Francisco Javier; Angulo-Barturen, Inigo; Jimenez-Diaz, Maria Belen; Ferrer-Bazaga, Santiago; Martinez, Maria S.; Gargallo-Viola, Domingo; Mathis, Amanda; Kess
BRITISH JOURNAL OF PHARMACOLOGY
0007-1188 (2020)
DOI /
10.1111/bph.15292
Gold other
