Clinical Medicine


  Listando 42 trabajos del autor/autora 38
Lista de trabajos en el área Clinical Medicine
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Article Cabazitaxel versus Abiraterone or Enzalutamide in Metastatic Prostate Cancer de Wit, Ronald; de Bono, Johann; Sternberg, Cora N.; Fizazi, Karim; Tombal, Bertrand; Wuelfing, Christian; Kramer, Gero; Eymard, Jean-Christophe; Bamias, Aristotelis; Carles, Joan; Iacovelli, Roberto; Melichar, Bohuslav; Sverrisdottir, Asgerdur; Theodore, NEW ENGLAND JOURNAL OF MEDICINE 0028-4793 (2019) DOI / 10.1056/nejmoa1911206 Bronze, Green published
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Article An adaptive, biomarker-directed platform study of durvalumab in combination with targeted therapies in advanced urothelial cancer Powles, Thomas; Carroll, Danielle; Chowdhury, Simon; Gravis, Gwenaelle; Joly, Florence; Carles, Joan; Flechon, Aude; Maroto, Pablo; Petrylak, Daniel; Rolland, Frederic; Cook, Natalie; Balar, Arjun V.; Sridhar, Srikala S.; Galsky, Matthew D.; Grivas, Petros NATURE MEDICINE 1078-8956 (2021) DOI / 10.1038/s41591-021-01317-6
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Article Phase III Study Comparing a Reduced Dose of Cabazitaxel (20 mg/m(2)) and the Currently Approved Dose (25 mg/m(2)) in Postdocetaxel Patients With Metastatic Castration-Resistant Prostate Cancer-PROSELICA Eisenberger, Mario; Hardy-Bessard, Anne-Claire; Kim, Choung Soo; Geczi, Lajos; Ford, Daniel; Mourey, Loic; Carles, Joan; Parente, Phillip; Font, Albert; Kacso, Gabriel; Chadjaa, Mustapha; Zhang, Wenping; Bernard, John; de Bono, Johann JOURNAL OF CLINICAL ONCOLOGY 0732-183X (2017) DOI / 10.1200/jco.2016.72.1076
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Article Phase III Trial of PROSTVAC in Asymptomatic or Minimally Symptomatic Metastatic Castration-Resistant Prostate Cancer Gulley, James L.; Borre, Michael; Vogelzang, Nicholas J.; Ng, Siobhan; Agarwal, Neeraj; Parker, Chris C.; Pook, David W.; Rathenborg, Per; Flaig, Thomas W.; Carles, Joan; Saad, Fred; Shore, Neal D.; Chen, Liddy; Heery, Christopher R.; Gerritsen, Winald R.; JOURNAL OF CLINICAL ONCOLOGY 0732-183X (2019) DOI / 10.1200/jco.18.02031 Green published, Hybrid
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Article Seizure Rates in Enzalutamide-Treated Men With Metastatic Castration-Resistant Prostate Cancer and Risk of Seizure The UPWARD Study Slovin, Susan; Clark, William; Carles, Joan; Krivoshik, Andrew; Park, Jung Wook; Wang, Fong; George, Daniel JAMA ONCOLOGY 2374-2437 (2018) DOI / 10.1001/jamaoncol.2017.3361 Green published, Bronze
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Article Advanced Prostate Cancer with ATM Loss: PARP and ATR Inhibitors Neeb, Antje; Herranz, Nicolas; Arce-Gallego, Sara; Miranda, Susana; Buroni, Lorenzo; Yuan, Wei; Athie, Alejandro; Casals, Teresa; Carmichael, Juliet; Nava Rodrigues, Daniel; Gurel, Bora; Rescigno, Pasquale; Rekowski, Jan; Welti, Jon; Riisnaes, Ruth; Gil, V EUROPEAN UROLOGY 0302-2838 (2021) DOI / 10.1016/j.eururo.2020.10.029 Gold other
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Article A CT-based Radiomics Signature Is Associated with Response to Immune Checkpoint Inhibitors in Advanced Solid Tumors Ligero, Marta; Garcia-Ruiz, Alonso; Viaplana, Cristina; Villacampa, Guillermo; Raciti, Maria, V; Landa, Jaid; Matos, Ignacio; Martin-Liberal, Juan; Ochoa-de-Olza, Maria; Hierro, Cinta; Mateo, Joaquin; Gonzalez, Macarena; Morales-Barrera, Rafael; Suarez, Cr RADIOLOGY 0033-8419 (2021) DOI / 10.1148/radiol.2021200928
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Article Capturing Hyperprogressive Disease with Immune-Checkpoint Inhibitors Using RECIST 1.1 Criteria Matos, Ignacio; Martin-Liberal, Juan; Garcia-Ruiz, Alonso; Hierro, Cinta; Ochoa de Olza, Maria; Viaplana, Cristina; Azaro, Analia; Vieito, Maria; Brana, Irene; Mur, Gemma; Ros, Javier; Mateos, Jose; Villacampa, Guillermo; Berche, Roger; Oliveira, Mafalda; CLINICAL CANCER RESEARCH 1078-0432 (2020) DOI / 10.1158/1078-0432.ccr-19-2226 Bronze
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Article Evolving Landscape of Molecular Prescreening Strategies for Oncology Early Clinical Trials Dienstmann, Rodrigo; Garralda, Elena; Aguilar, Susana; Sala, Gemma; Viaplana, Cristina; Ruiz-Pace, Fiorella; Gonzalez-Zorelle, Jenifer; Grazia LoGiacco, Deborah; Ogbah, Zighereda; Ramos Masdeu, Laia; Mancuso, Francesco; Fasani, Roberta; Jimenez, Jose; Mart JCO PRECISION ONCOLOGY (2020) DOI / 10.1200/po.19.00398 Gold other, Green published
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Article Quality of life in patients with metastatic prostate cancer following treatment with cabazitaxel versus abiraterone or enzalutamide (CARD): an analysis of a randomised, multicentre, open-label, phase 4 study Fizazi, Karim; Kramer, Gero; Eymard, Jean-Christophe; Sternberg, Cora N.; de Bono, Johann; Castellano, Daniel; Tombal, Bertrand; Whuelfing, Christian; Liontos, Michael; Carles, Joan; Iacovelli, Roberto; Melichar, Bohuslav; Sverrisdottir, Asgerdur; Theodore LANCET ONCOLOGY 1470-2045 (2020) DOI / 10.1016/s1470-2045(20)30449-6
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Article Molecular Diagnosis of Diffuse Gliomas through Sequencing of Cell-Free Circulating Tumor DNA from Cerebrospinal Fluid Martinez-Ricarte, Francisco; Mayor, Regina; Martinez-Saez, Elena; Rubio-Perez, Carlota; Pineda, Estela; Cordero, Esteban; Cicuendez, Marta; Poca, Maria A.; Lopez-Bigas, Nuria; Ramon y Cajal, Santiago; Vieito, Maria; Carles, Joan; Tabernero, Josep; Vivancos CLINICAL CANCER RESEARCH 1078-0432 (2018) DOI / 10.1158/1078-0432.ccr-17-3800 Bronze
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Article The Phase 3 COU-AA-302 Study of Abiraterone Acetate Plus Prednisone in Men with Chemotherapy-naive Metastatic Castration-resistant Prostate Cancer: Stratified Analysis Based on Pain, Prostate-specific Antigen, and Gleason Score Miller, Kurt; Carles, Joan; Gschwend, Juergen E.; van Poppel, Hendrik; Diels, Joris; Brookman-May, Sabine D. EUROPEAN UROLOGY 0302-2838 (2018) DOI / 10.1016/j.eururo.2017.08.035
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Article Phase I prognostic online (PIPO): A web tool to improve patient selection for oncology early phase clinical trials Matos, Ignacio; Villacampa, Guillermo; Hierro, Cinta; Martin-Liberal, Juan; Berche, Roger; Pedrola, Anna; Brana, Irene; Azaro, Analia; Vieito, Maria; Saavedra, Omar; Gardeazabal, Itziar; Hernando-Calvo, Alberto; Alonso, Guzman; Galvao, Vladimir; de Olza, M EUROPEAN JOURNAL OF CANCER 0959-8049 (2021) DOI / 10.1016/j.ejca.2021.05.040 Hybrid
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Article Efficacy and Safety of Cabazitaxel Versus Abiraterone or Enzalutamide in Older Patients with Metastatic Castration-resistant Prostate Cancer in the CARD Study Sternberg, Cora N.; Castellano, Daniel; de Bono, Johann; Fizazi, Karim; Tombal, Bertrand; Wuelfing, Christian; Kramer, Gero; Eymard, Jean-Christophe; Bamias, Aristotelis; Carles, Joan; Iacovelli, Roberto; Melichar, Bohuslav; Sverrisdottir, Asgerdur; Theodo EUROPEAN UROLOGY 0302-2838 (2021) DOI / 10.1016/j.eururo.2021.06.021
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Article Clinical outcome after progressing to frontline and second-line Anti-PD-1/PD-L1 in advanced urothelial cancer De Liano Lista, Alfonso Gomez; van Dijk, Nick; Oria de Rueda, Guillermo de Velasco; Necchi, Andrea; Lavaud, Pernelle; Morales-Barrera, Rafael; Alonso Gordoa, Teresa; Maroto, Pablo; Ravaud, Alain; Duran, Ignacio; Szabados, Bernadett; Castellano, Daniel; Gia EUROPEAN UROLOGY 0302-2838 (2020) DOI / 10.1016/j.eururo.2019.10.004
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Article E3 ubiquitin ligase Atrogin-1 mediates adaptive resistance to KIT-targeted inhibition in gastrointestinal stromal tumor Garcia-Valverde, Alfonso; Rosell, Jordi; Sayols, Sergi; Gomez-Peregrina, David; Pilco-Janeta, Daniel F.; Olivares-Rivas, Ivan; de Alava, Enrique; Maurel, Joan; Rubio-Casadevall, Jordi; Esteve, Anna; Gut, Marta; Valverde, Claudia; Barretina, Jordi; Carles, ONCOGENE 0950-9232 (2021) DOI / 10.1038/s41388-021-02049-0
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Editorial Material Towards a New Classification for Metastatic Prostate Cancer Mateo, Joaquin; Carles, Joan EUROPEAN UROLOGY 0302-2838 (2019) DOI / 10.1016/j.eururo.2018.10.058
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Article Baseline neutrophil-to-lymphocyte ratio as a predictive and prognostic biomarker in patients with metastatic castration-resistant prostate cancer treated with cabazitaxel versus abiraterone or enzalutamide in the CARD study de Wit, R.; Wuelfing, C.; Castellano, D.; Kramer, G.; Eymard, J. -C.; Sternberg, C. N.; Fizazi, K.; Tombal, B.; Bamias, A.; Carles, J.; Iacovelli, R.; Melichar, B.; Sverrisdottir, A.; Theodore, C.; Feyerabend, S.; Helissey, C.; Foster, M. C.; Ozatilgan, A. ESMO OPEN (2021) DOI / 10.1016/j.esmoop.2021.100241 Green published, Gold
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Review Targeting DNA Repair Defects for Precision Medicine in Prostate Cancer Athie, Alejandro; Arce-Gallego, Sara; Gonzalez, Macarena; Morales-Barrera, Rafael; Suarez, Cristina; Casals Galobart, Teresa; Hernandez Viedma, Gonzalo; Carles, Joan; Mateo, Joaquin CURRENT ONCOLOGY REPORTS 1523-3790 (2019) DOI / 10.1007/s11912-019-0790-6
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Article Radium-223 Within the Evolving Treatment Options for Metastatic Castration-resistant Prostate Cancer: Recommendations from a European Expert Working Group O'Sullivan, Joe M.; Carles, Joan; Cathomas, Richard; Gomez-Iturriaga, Alfonso; Heinrich, Daniel; Kramer, Gero; Ost, Piet; van Oort, Inge; Tombal, Bertrand EUROPEAN UROLOGY ONCOLOGY (2020) DOI / 10.1016/j.euo.2019.02.007
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Article Cell Plasticity-Related Phenotypes and Taxanes Resistance in Castration-Resistant Prostate Cancer Jimenez, Natalia; Reig, Oscar; Montalbo, Ruth; Mila-Guasch, Maria; Nadal-Dieste, Lluis; Castellano, Giancarlo; Jose Lozano, Juan; Victoria, Ivan; Font, Albert; Rodriguez-Vida, Alejo; Carles, Joan; Suarez, Cristina; Domenech, Montserrat; Sala-Gonzalez, Nuri FRONTIERS IN ONCOLOGY 2234-943X (2020) DOI / 10.3389/fonc.2020.594023 Gold DOAJ, Green published
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Article The influence of treatment sequence in the prognostic value of TMPRSS2-ERG as biomarker of taxane resistance in castration-resistant prostate cancer Marin-Aguilera, Mercedes; Reig, Oscar; Mila-Guasch, Maria; Font, Albert; Domenech, Montserrat; Rodriguez-Vida, Alejo; Carles, Joan; Suarez, Cristina; Gonzalez del Alba, Aranzazu; Jimenez, Natalia; Victoria, Ivan; Sala-Gonzalez, Nuria; Jose Ribal, Maria; Lo INTERNATIONAL JOURNAL OF CANCER 0020-7136 (2019) DOI / 10.1002/ijc.32238
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Article Phase 2 Randomized Study of Radiation Therapy and 3-Year Androgen Deprivation With or Without Concurrent Weekly Docetaxel in High-Risk Localized Prostate Cancer Patients Carles, Joan; Gallardo, Enrique; Domenech, Montserrat; Font, Albert; Bellmunt, Joaquim; Figols, Mariona; Mellado, Begona; Isabel Saez, Maria; Suarez, Cristina; Jose Mendez, Maria; Maroto, Pablo; Luque, Raquel; de Portugal, Teresa; Aldabo, Ramon; Bonfill, T INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 0360-3016 (2019) DOI / 10.1016/j.ijrobp.2018.10.005
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Article Preclinical Activity of PI3K Inhibitor Copanlisib in Gastrointestinal Stromal Tumor Garcia-Valverde, Alfonso; Rosell, Jordi; Serna, Garazi; Valverde, Claudia; Carles, Joan; Nuciforo, Paolo; Fletcher, Jonathan A.; Arribas, Joaquin; Politz, Oliver; Serrano, Cesar MOLECULAR CANCER THERAPEUTICS 1535-7163 (2020) DOI / 10.1158/1535-7163.mct-19-1069
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Article Clinical value of next generation sequencing of plasma cell-free DNA in gastrointestinal stromal tumors Serrano, Cesar; Vivancos, Ana; Lopez-Pousa, Antonio; Matito, Judit; Mancuso, Francesco M.; Valverde, Claudia; Quiroga, Sergi; Landolfi, Stefania; Castro, Sandra; Dopazo, Cristina; Sebio, Ana; Virgili, Anna C.; Menso, Maria M.; Martin-Broto, Javier; Sanso, BMC CANCER (2020) DOI / 10.1186/s12885-020-6597-x Gold DOAJ, Green published
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Article Telomerase-based GX301 cancer vaccine in patients with metastatic castration-resistant prostate cancer: a randomized phase II trial Filaci, Gilberto; Fenoglio, Daniela; Nole, Franco; Zanardi, Elisa; Tomasello, Laura; Aglietta, Massimo; Del Conte, Gianluca; Carles, Joan; Morales-Barrera, Rafael; Guglielmini, Pamela; Scagliotti, Giorgio; Signori, Alessio; Parodi, Alessia; Kalli, Francesc CANCER IMMUNOLOGY IMMUNOTHERAPY 0340-7004 (2021) DOI / 10.1007/s00262-021-03024-0 Green published, Hybrid
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Review Selection and monitoring of patients with metastatic castration-resistant prostate cancer for treatment with radium-223 Rodriguez-Vida, A.; Torregrosa, M. D.; Pinto, A.; Climent, M. A.; Olmos, D.; Carles, J. CLINICAL & TRANSLATIONAL ONCOLOGY 1699-048X (2018) DOI / 10.1007/s12094-017-1785-0
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Article Effect of Baseline Characteristics on Cabazitaxel Treatment Duration in Patients with Metastatic Castration-Resistant Prostate Cancer: A Post Hoc Analysis of the Compassionate Use/Expanded Access Programs and CAPRISTANA Registry Malik, Zafar; Di Lorenzo, Giuseppe; Pichler, Angelika; De Giorgi, Ugo; Hitier, Simon; Ecstein-Fraisse, Evelyne; Ozatilgan, Ayse; Carles, Joan CANCERS (2020) DOI / 10.3390/cancers12040995 Gold DOAJ, Green published
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Article SEOM clinical guidelines for the treatment of metastatic prostate cancer (2017) Cassinello, J.; Arranz, J. A.; Piulats, J. M.; Sanchez, A.; Perez-Valderrama, B.; Mellado, B.; Climent, M. A.; Olmos, D.; Carles, J.; Lazaro, M. CLINICAL & TRANSLATIONAL ONCOLOGY 1699-048X (2018) DOI / 10.1007/s12094-017-1783-2 Green published, Gold other
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Review PARP inhibitors in advanced prostate cancer: when to use them? Diaz-Mejia, Nely; Garcia-Illescas, David; Morales-Barrera, Rafael; Suarez, Cristina; Planas, Jacques; Maldonado, Xavier; Carles, Joan; Mateo, Joaquin ENDOCRINE-RELATED CANCER 1351-0088 (2021) DOI / 10.1530/erc-21-0133 Bronze
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Article Clinicopathological and Molecular Characterization of Metastatic Gastrointestinal Stromal Tumors with Prolonged Benefit to Frontline Imatinib Serrano, Cesar; Garcia-del-Muro, Xavier; Valverde, Claudia; Sebio, Ana; Duran, Jose; Manzano, Aranzazu; Pajares, Isabel; Hindi, Nadia; Landolfi, Stefania; Jimenez, Laura; Rubio-Casadevall, Jordi; Estival, Anna; Lavernia, Javier; Jose Safont, Maria; Pericay ONCOLOGIST 1083-7159 (2019) DOI / 10.1634/theoncologist.2018-0032 Green published, Bronze
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Review Novel Insights into the Treatment of Imatinib-Resistant Gastrointestinal Stromal Tumors Serrano, Cesar; George, Suzanne; Valverde, Claudia; Olivares, David; Garcia-Valverde, Alfonso; Suarez, Cristina; Morales-Barrera, Rafael; Carles, Joan TARGETED ONCOLOGY 1776-2596 (2017) DOI / 10.1007/s11523-017-0490-9
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Review Metastatic nonclear renal cell carcinoma current review in evolving treatment strategies Suarez, Cristina; Diaz-Mejia, Nely; Morales-Barrera, Rafael; Gonzalez, Macarena; Mateo, Joaquin; Carles, Joan CURRENT OPINION IN UROLOGY 0963-0643 (2021) DOI / 10.1097/mou.0000000000000869
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Article Prognostic Index Model for Progression-Free Survival in Chemotherapy-Naive Metastatic Castration-Resistant Prostate Cancer Treated With Abiraterone Acetate Plus Prednisone Ryan, Charles J.; Kheoh, Thian; Li, Jinhui; Molina, Arturo; De Porre, Peter; Carles, Joan; Efstathiou, Eleni; Kantoff, Philip W.; Mulders, Peter F. A.; Saad, Fred; Chi, Kim N. CLINICAL GENITOURINARY CANCER 1558-7673 (2018) DOI / 10.1016/j.clgc.2017.07.014 Green accepted
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Review Unveiling changes in the landscape of patient populations in cancer early drug development Hierro, Cinta; Azaro, Analia; Argiles, Guillem; Elez, Elena; Gomez, Patricia; Carles, Joan; Rodon, Jordi ONCOTARGET 1949-2553 (2017) DOI / 10.18632/oncotarget.13258 Gold other, Green published
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Article Effect of Visceral Disease Site on Outcomes in Patients With Metastatic Castration-resistant Prostate Cancer Treated With Enzalutamide in the PREVAIL Trial Alumkal, Joshi J.; Chowdhury, Simon; Loriot, Yohann; Sternberg, Cora N.; de Bono, Johann S.; Tombal, Bertrand; Carles, Joan; Flaig, Thomas W.; Dorff, Tanya B.; De Phung; Forer, David; Noonberg, Sarah B.; Mansbach, Hank; Beer, Tomasz M.; Higano, Celestia S. CLINICAL GENITOURINARY CANCER 1558-7673 (2017) DOI / 10.1016/j.clgc.2017.02.007
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Article Radium-223 in asymptomatic patients with castration-resistant prostate cancer and bone metastases treated in an international early access program Heidenreich, Axel; Gillessen, Silke; Heinrich, Daniel; Keizman, Daniel; O'Sullivan, Joe M.; Carles, Joan; Wirth, Manfred; Miller, Kurt; Reeves, John; Seger, Monica; Nilsson, Sten; Saad, Fred BMC CANCER (2019) DOI / 10.1186/s12885-018-5203-y Gold DOAJ, Green published
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Review The future of bladder cancer therapy: Optimizing the inhibition of the fibroblast growth factor receptor Morales-Barrera, Rafael; Suarez, Cristina; Gonzalez, Macarena; Valverde, Claudia; Serra, Ester; Mateo, Joaquin; Raventos, Carles; Maldonado, Xavier; Morote, Juan; Carles, Joan CANCER TREATMENT REVIEWS 0305-7372 (2020) DOI / 10.1016/j.ctrv.2020.102000
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Article Free Testosterone During Androgen Deprivation Therapy Predicts Castration-Resistant Progression Better Than Total Testosterone Regis, Lucas; Planas, Jacques; Carles, Joan; Maldonado, Xavier; Comas, Inma; Ferrer, Roser; Morote, Juan PROSTATE 0270-4137 (2017) DOI / 10.1002/pros.23256
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Article Radium-223 international early access program: results from the Spanish subset Carles, Joan; Jose Mendez, Ma; Pinto, Alvaro; Isabel Saez, Ma; Arranz, Jose A.; Maroto, Pablo; Lopez-Criado, Pilar; Mellado, Begona; Garcia Donas, Jesus; Hernando, Susana; Leon, Luis; Gonzalez del Alba, Aranzazu; Lainez, Nuria; Esteban, Emilio; Reynes, Gas FUTURE ONCOLOGY 1479-6694 (2018) DOI / 10.2217/fon-2017-0297
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Article Disease Characteristics and Completion of Treatment in Patients With Metastatic Castration-Resistant Prostate Cancer Treated With Radium-223 in an International Early Access Program Saad, Fred; Gillessen, Silke; Heinrich, Daniel; Keizman, Daniel; O'Sullivan, Joe M.; Nilsson, Sten; Miller, Kurt; Wirth, Manfred; Reeves, John; Seger, Monica; Carles, Joan; Heidenreich, Axel CLINICAL GENITOURINARY CANCER 1558-7673 (2019) DOI / 10.1016/j.clgc.2019.05.012 Gold other
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Article Second-line Chemotherapy in Older Patients With Metastatic Urothelial Carcinoma: Pooled Analysis of 10 Second-line Studies Salah, Samer; Lee, Jae-Lyun; Rozzi, Antonio; Kitamura, Hiroshi; Matsumoto, Kazumasa; Vis, Daniel J.; Srinivas, Sandy; Morales-Barrera, Rafael; Carles, Joan; Al-Rimawi, Dalia; Lee, Soonil; Kim, Ki Hong; Izumi, Kouji; Lewin, Jeremy CLINICAL GENITOURINARY CANCER 1558-7673 (2017) DOI / 10.1016/j.clgc.2016.12.014

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