Molecular Biology & Genetics
Listando 29 trabajos del autor/autora 38
Lista de trabajos en el área Molecular Biology & Genetics
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156
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7
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Article
The SWI/SNF chromatin remodeling complex helps resolve R-loop-mediated transcription-replication conflicts
Bayona-Feliu, Aleix; Barroso, Sonia; Munoz, Sergio; Aguilera, Andres
NATURE GENETICS
1061-4036 (2021)
DOI /
10.1038/s41588-021-00867-2
Green submitted
Mentions
30
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0
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8
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0
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Article
Histone Mutants Separate R Loop Formation from Genome Instability Induction
Garcia-Pichardo, Desire; Canas, Juan C.; Garcia-Rubio, Maria L.; Gomez-Gonzalez, Belen; Rondon, Ana G.; Aguilera, Andres
MOLECULAR CELL
1097-2765 (2017)
DOI /
10.1016/j.molcel.2017.05.014
Green published, Bronze
Mentions
1
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0
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9
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0
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Article
A new role for Rrm3 in repair of replication-born DNA breakage by sister chromatid recombination
Munoz-Galvan, Sandra; Garcia-Rubio, Maria; Ortega, Pedro; Ruiz, Jose F.; Jimeno, Sonia; Pardo, Benjamin; Gomez-Gonzalez, Belen; Aguilera, Andres
PLOS GENETICS
1553-7390 (2017)
DOI /
10.1371/journal.pgen.1006781
Green published, Gold, Green submitted
Mentions
13
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0
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5
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0
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Article
TDP-43 mutations link Amyotrophic Lateral Sclerosis with R-loop homeostasis and R loop-mediated DNA damage
Gianini, Marta; Bayona-Feliu, Aleix; Sproviero, Daisy; Barroso, Sonia I.; Cereda, Cristina; Aguilera, Andres
PLOS GENETICS
1553-7390 (2020)
DOI /
10.1371/journal.pgen.1009260
Green published, Gold
Mentions
11
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0
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5
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0
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Article
Physical proximity of chromatin to nuclear pores prevents harmful R loop accumulation contributing to maintain genome stability
Garcia-Benitez, Francisco; Gaillarda, Helene; Aguilera, Andres
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
0027-8424 (2017)
DOI /
10.1073/pnas.1707845114
Green published, Bronze
Mentions
60
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0
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0
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0
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Article
BRCA2 promotes R-loop resolution by DDX5 helicase at DNA breaks to facilitate their repair by homologous recombination
Sessa, Gaetana; Gomez-Gonzalez, Belen; Silva, Sonia; Perez-Calero, Carmen; Beaurepere, Romane; Barroso, Sonia; Martineau, Sylvain; Martin, Charlotte; Ehlen, Asa; Martinez, Juan S.; Lombard, Berangere; Loew, Damarys; Vagner, Stephan; Aguilera, Andres; Carre
EMBO JOURNAL
0261-4189 (2021)
DOI /
10.15252/embj.2020106018
Green published
Mentions
16
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0
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2
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0
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Article
Coordinated Activity of Y Family TLS Polymerases and EXO1 Protects Non-S Phase Cells from UV-Induced Cytotoxic Lesions
Sertic, Sarah; Mollica, Antonio; Campus, Ilaria; Roma, Stefania; Tumini, Emanuela; Aguilera, Andres; Muzi-Falconi, Marco
MOLECULAR CELL
1097-2765 (2018)
DOI /
10.1016/j.molcel.2018.02.017
Bronze
Mentions
42
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0
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0
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0
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Article
The human nucleoporin Tpr protects cells from RNA-mediated replication stress
Kosar, Martin; Giannattasio, Michele; Piccini, Daniele; Maya-Mendoza, Apolinar; Garcia-Benitez, Francisco; Bartkova, Jirina; Barroso, Sonia I.; Gaillard, Helene; Martini, Emanuele; Restuccia, Umberto; Ramirez-Otero, Miguel Angel; Garre, Massimiliano; Verga
NATURE COMMUNICATIONS
(2021)
DOI /
10.1038/s41467-021-24224-3
Green published, Gold
Mentions
50
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0
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0
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0
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Review
R Loops: From Physiological to Pathological Roles
Garcia-Muse, Tatiana; Aguilera, Andres
CELL
0092-8674 (2019)
DOI /
10.1016/j.cell.2019.08.055
Green accepted, Bronze
Mentions
29
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0
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0
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0
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Article
Homologous recombination and Mus81 promote replication completion in response to replication fork blockage
Pardo, Benjamin; Moriel-Carretero, Maria; Vicat, Thibaud; Aguilera, Andres; Pasero, Philippe
EMBO REPORTS
1469-221X (2020)
DOI /
10.15252/embr.201949367
Bronze, Green published, Green submitted
Mentions
36
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0
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0
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0
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Article
Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability
Zatreanu, Diana; Han, Zhong; Mitter, Richard; Tumini, Emanuela; Williams, Hannah; Gregersen, Lea; Dirac-Svejstrup, A. Barbara; Roma, Stefania; Stewart, Aengus; Aguilera, Andres; Svejstrup, Jesper Q.
MOLECULAR CELL
1097-2765 (2019)
DOI /
10.1016/j.molcel.2019.07.037
Green published, Hybrid
Mentions
30
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0
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0
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0
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Editorial Material
R-Loops as Promoters of Antisense Transcription
Rondon, Ana G.; Aguilera, Andres
MOLECULAR CELL
1097-2765 (2019)
DOI /
10.1016/j.molcel.2019.11.001
Bronze
Mentions
23
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0
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0
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0
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Article
A transcription-based mechanism for oncogenic beta-catenin-induced lethality in BRCA1/2-deficient cells
Dagg, Rebecca A.; Zonderland, Gijs; Lombardi, Emilia Puig; Rossetti, Giacomo G.; Groelly, Florian J.; Barroso, Sonia; Tacconi, Eliana M. C.; Wright, Benjamin; Lockstone, Helen; Aguilera, Andres; Halazonetis, Thanos D.; Tarsounas, Madalena
NATURE COMMUNICATIONS
(2021)
DOI /
10.1038/s41467-021-25215-0
Gold, Green published
Mentions
13
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0
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0
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0
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Article
Heterogeneity of DNA damage incidence and repair in different chromatin contexts
Ortega, Pedro; Gomez-Gonzalez, Belen; Aguilera, Andres
DNA REPAIR
1568-7864 (2021)
DOI /
10.1016/j.dnarep.2021.103210
Green published, Hybrid
Mentions
17
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0
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0
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0
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Article
A Meiotic Checkpoint Alters Repair Partner Bias to Permit Inter-sister Repair of Persistent DSBs
Garcia-Muse, Tatiana; Galindo-Diaz, U.; Garcia-Rubio, M.; Martin, J. S.; Polanowska, J.; O'Reilly, N.; Aguilera, A.; Boulton, Simon J.
CELL REPORTS
2211-1247 (2019)
DOI /
10.1016/j.celrep.2018.12.074
Green published, Gold
Mentions
10
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0
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0
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0
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Article
Human THO-Sin3A interaction reveals new mechanisms to prevent R-loops that cause genome instability
Salas-Armenteros, Irene; Perez-Calero, Carmen; Bayona-Feliu, Aleix; Tumini, Emanuela; Luna, Rosa; Aguilera, Andres
EMBO JOURNAL
0261-4189 (2017)
DOI /
10.15252/embj.201797208
Bronze, Green published
Mentions
10
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0
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0
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0
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Review
Transcription-mediated replication hindrance: a major driver of genome instability
Gomez-Gonzalez, Belen; Aguilera, Andres
GENES & DEVELOPMENT
0890-9369 (2019)
DOI /
10.1101/gad.324517.119
Green published, Gold
Mentions
6
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0
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0
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0
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Review
Spontaneous DNA-RNA hybrids: differential impacts throughout the cell cycle
Gomez-Gonzalez, Belen; Barroso, Sonia; Herrera-Moyano, Emilia; Aguilera, Andres
CELL CYCLE
1538-4101 (2020)
DOI /
10.1080/15384101.2020.1728015
Mentions
8
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0
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0
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0
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Article
C. elegans THSC/TREX-2 deficiency causes replication stress and genome instability
Zheleva, Angelina; Camino, Lola P.; Fernandez-Fernandez, Nuria; Garcia-Rubio, Maria; Askjaer, Peter; Garcia-Muse, Tatiana; Aguilera, Andres
JOURNAL OF CELL SCIENCE
0021-9533 (2021)
DOI /
10.1242/jcs.258435
Hybrid, Green accepted
Mentions
11
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0
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0
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0
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Article
Yra1-bound RNA-DNA hybrids cause orientation-independent transcription-replication collisions and telomere instability
Garcia-Rubio, Maria; Aguilera, Paula; Lafuente-Barquero, Juan; Ruiz, Jose F.; Simon, Marie-Noelle; Geli, Vincent; Rondon, Ana G.; Aguilera, Andres
GENES & DEVELOPMENT
0890-9369 (2018)
DOI /
10.1101/gad.311274.117
Green published, Green submitted, Gold
Mentions
6
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0
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0
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0
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Article
The Antitumor Drugs Trabectedin and Lurbinectedin Induce Transcription-Dependent Replication Stress and Genome Instability
Tumini, Emanuela; Herrera-Moyano, Emilia; San Martin-Alonso, Marta; Barroso, Sonia; Galmarini, Carlos M.; Aguilera, Andres
MOLECULAR CANCER RESEARCH
1541-7786 (2019)
DOI /
10.1158/1541-7786.mcr-18-0575
Green accepted, Bronze
Mentions
4
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0
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0
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0
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Article
The DNA damage response acts as a safeguard against harmful DNA-RNA hybrids of different origins
Barroso, Sonia; Herrera-Moyano, Emilia; Munoz, Sergio; Garcia-Rubio, Maria; Gomez-Gonzalez, Belen; Aguilera, Andres
EMBO REPORTS
1469-221X (2019)
DOI /
10.15252/embr.201847250
Green published, Green accepted
Mentions
4
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0
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0
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0
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Article
The Smc5/6 complex regulates the yeast Mph1 helicase at RNA-DNA hybrid-mediated DNA damage
Lafuente-Barquero, Juan; Luke-Glaser, Sarah; Graf, Marco; Silva, Sonia; Gomez-Gonzalez, Belen; Lockhart, Arianna; Lisby, Michael; Aguilera, Andres; Luke, Brian
PLOS GENETICS
1553-7390 (2017)
DOI /
10.1371/journal.pgen.1007136
Green published, Green submitted, Gold
Mentions
4
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0
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0
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0
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Article
Depletion of the MFAP1/SPP381 Splicing Factor Causes R-Loop-Independent Genome Instability
Salas-Armenteros, Irene; Barroso, Sonia I.; Rondon, Ana G.; Perez, Monica; Andujar, Eloisa; Luna, Rosa; Aguilera, Andres
CELL REPORTS
2211-1247 (2019)
DOI /
10.1016/j.celrep.2019.07.010
Green published, Gold
Mentions
4
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0
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0
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0
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Article
DNA-RNA hybrids: the risks of DNA breakage during transcription
Aguilera, Andres; Gomez-Gonzalez, Belen
NATURE STRUCTURAL & MOLECULAR BIOLOGY
1545-9993 (2017)
DOI /
10.1038/nsmb.3395
Green submitted
Mentions
1
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0
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0
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0
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Article
Differential effect of the overexpression of Rad2/XPG family endonucleases on genome integrity in yeast and human cells
Jimeno, Sonia; Herrera-Moyano, Emilia; Ortega, Pedro; Aguilera, Andres
DNA REPAIR
1568-7864 (2017)
DOI /
10.1016/j.dnarep.2017.06.030
Mentions
2
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0
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0
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0
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Editorial Material
The need to regulate replication fork speed
Gomez-Gonzalez, Belen; Aguilera, Andres
SCIENCE
0036-8075 (2017)
DOI /
10.1126/science.aaq0678
Green accepted
Mentions
2
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0
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0
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0
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Article
R-Loop-Mediated ssDNA Breaks Accumulate Following Short-Term Exposure to the HDAC Inhibitor Romidepsin
Safari, Maryam; Litman, Thomas; Robey, Robert W.; Aguilera, Andres; Chakraborty, Arup R.; Reinhold, William C.; Basseville, Agnes; Petrukhin, Lubov; Scotto, Luigi; O'Connor, Owen A.; Pommier, Yves; Fojo, Antonio T.; Bates, Susan E.
MOLECULAR CANCER RESEARCH
1541-7786 (2021)
DOI /
10.1158/1541-7786.mcr-20-0833
Green published
Mentions
2
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0
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0
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Review
Origin matters: spontaneous DNA-RNA hybrids do not form in trans as a source of genome instability
Gomez-Gonzalez, Belen; Aguilera, Andres
CURRENT GENETICS
0172-8083 (2020)
DOI /
10.1007/s00294-020-01117-4