Biology & Biochemistry
Listando 19 trabajos del autor/autora 38
Lista de trabajos en el área Biology & Biochemistry
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Article
Membrane cholesterol access into a G-protein-coupled receptor
Guixa-Gonzalez, Ramon; Albasanz, Jose L.; Rodriguez-Espigares, Ismael; Pastor, Manuel; Sanz, Ferran; Marti-Solano, Maria; Manna, Moutusi; Martinez-Seara, Hector; Hildebrand, Peter W.; Martin, Mairena; Selent, Jana
NATURE COMMUNICATIONS
(2017)
DOI /
10.1038/ncomms14505
Gold, Green published, Green submitted
Mentions
39
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0
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10
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0
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Article
A molecular sensor for cholesterol in the human serotonin(1A) receptor
Kumar, G. Aditya; Sarkar, Parijat; Stepniewski, Tomasz Maciej; Jafurulla, Md; Singh, Shishu Pal; Selent, Jana; Chattopadhyay, Amitabha
SCIENCE ADVANCES
2375-2548 (2021)
DOI /
10.1126/sciadv.abh2922
Green published, Gold
Mentions
138
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GPCRmd uncovers the dynamics of the 3D-GPCRome
Rodriguez-Espigares, Ismael; Torrens-Fontanals, Mariona; Tiemann, Johanna K. S.; Aranda-Garcia, David; Manuel Ramirez-Anguita, Juan; Stepniewski, Tomasz Maciej; Worp, Nathalie; Varela-Rial, Alejandro; Morales-Pastor, Adrian; Medel-Lacruz, Brian; Pandy-Szek
NATURE METHODS
1548-7091 (2020)
DOI /
10.1038/s41592-020-0884-y
Mentions
13
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0
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8
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0
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Article
C-edge loops of arrestin function as a membrane anchor
Lally, Ciara C. M.; Bauer, Brian; Selent, Jana; Sommer, Martha E.
NATURE COMMUNICATIONS
(2017)
DOI /
10.1038/ncomms14258
Gold DOAJ, Green published
Mentions
65
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3
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Distinct phosphorylation sites in a prototypical GPCR differently orchestrate beta-arrestin interaction, trafficking, and signaling
Dwivedi-Agnihotri, Hemlata; Chaturvedi, Madhu; Baidya, Mithu; Stepniewski, Tomasz Maciej; Pandey, Shubhi; Maharana, Jagannath; Srivastava, Ashish; Caengprasath, Natarin; Hanyaloglu, Aylin C.; Selent, Jana; Shukla, Arun K.
SCIENCE ADVANCES
2375-2548 (2020)
DOI /
10.1126/sciadv.abb8368
Gold, Green published
Mentions
46
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Key phosphorylation sites inGPCRs orchestrate the contribution of beta-Arrestin 1 inERK1/2 activation
Baidya, Mithu; Kumari, Punita; Dwivedi-Agnihotri, Hemlata; Pandey, Shubhi; Chaturvedi, Madhu; Maciej Stepniewski, Tomasz; Kawakami, Kouki; Cao, Yubo; Laporte, Stphane A.; Selent, Jana; Inoue, Asuka; Shukla, Arun K.
EMBO REPORTS
1469-221X (2020)
DOI /
10.15252/embr.201949886
Bronze, Green published
Mentions
28
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0
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Structural dynamics bridge the gap between the genetic and functional levels of GPCRs
Torrens-Fontanals, Mariona; Stepniewski, Tomasz M.; Gloriam, David E.; Selent, Jana
CURRENT OPINION IN STRUCTURAL BIOLOGY
0959-440X (2021)
DOI /
10.1016/j.sbi.2021.04.005
Mentions
27
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The antioxidant resveratrol acts as a non-selective adenosine receptor agonist
Sanchez-Melgar, A.; Albasanz, J. L.; Guixa-Gonzalez, R.; Saleh, N.; Selent, J.; Martin, M.
FREE RADICAL BIOLOGY AND MEDICINE
0891-5849 (2019)
DOI /
10.1016/j.freeradbiomed.2019.03.019
Mentions
20
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Can molecular dynamics simulations improve the structural accuracy and virtual screening performance of GPCR models?
Kapla, Jon; Rodriguez Espigares, Ismael; Ballante, Flavio; Selent, Jana; Carlsson, Jens
PLOS COMPUTATIONAL BIOLOGY
1553-734X (2021)
DOI /
10.1371/journal.pcbi.1008936
Gold DOAJ, Green published
Mentions
12
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Discovery of a dual Ras and ARF6 inhibitor from a GPCR endocytosis screen
Giubilaro, Jenna; Schuetz, Doris A.; Stepniewski, Tomasz M.; Namkung, Yoon; Khoury, Etienne; Lara-Marquez, Monica; Campbell, Shirley; Beautrait, Alexandre; Armando, Sylvain; Radresa, Olivier; Duchaine, Jean; Lamarche-Vane, Nathalie; Claing, Audrey; Selent,
NATURE COMMUNICATIONS
(2021)
DOI /
10.1038/s41467-021-24968-y
Green submitted, Gold, Green published
Mentions
7
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0
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0
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Performance of virtual screening against GPCR homology models: Impact of template selection and treatment of binding site plasticity
Jaiteh, Mariama; Rodriguez-Espigares, Ismael; Selent, Jana; Carlsson, Jens
PLOS COMPUTATIONAL BIOLOGY
1553-734X (2020)
DOI /
10.1371/journal.pcbi.1007680
Gold, Green published
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7
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Ligand with Two Modes of Interaction with the Dopamine D-2 Receptor-An Induced-Fit Mechanism of Insurmountable Antagonism
Agren, Richard; Zeberg, Hugo; Stepniewski, Tomasz Maciej; Free, R. Benjamin; Reilly, Sean W.; Luedtke, Robert R.; Arhem, Peter; Ciruela, Francisco; Sibley, David R.; Mach, Robert H.; Selent, Jana; Nilsson, Johanna; Sahlholm, Kristoffer
ACS CHEMICAL NEUROSCIENCE
1948-7193 (2020)
DOI /
10.1021/acschemneuro.0c00477
Green published, Gold other
Mentions
5
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Palmitoylation of cysteine 415 of CB1 receptor affects ligand-stimulated internalization and selective interaction with membrane cholesterol and caveolin 1
Oddi, Sergio; Stepniewski, Tomasz Maciej; Totaro, Antonio; Selent, Jana; Scipioni, Lucia; Dufrusine, Beatrice; Fezza, Filomena; Dainese, Enrico; Maccarrone, Mauro
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
1388-1981 (2017)
DOI /
10.1016/j.bbalip.2017.02.004
Mentions
1
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A highly conserved delta-opioid receptor region determines RGS4 interaction
Karoussiotis, Christos; Marti-Solano, Maria; Maciej Stepniewski, Tomasz; Symeonof, Alexandra; Selent, Jana; Georgoussi, Zafiroula
FEBS JOURNAL
1742-464X (2019)
DOI /
10.1111/febs.15033
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1
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0
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Dopamine D-2 Receptor Agonist Binding Kinetics-Role of a Conserved Serine Residue
agren, Richard; Stepniewski, Tomasz Maciej; Zeberg, Hugo; Selent, Jana; Sahlholm, Kristoffer
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
1661-6596 (2021)
DOI /
10.3390/ijms22084078
Gold DOAJ, Green published
Mentions
2
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0
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Entrectinib-A SARS-CoV-2 Inhibitor in Human Lung Tissue (HLT) Cells
Peralta-Garcia, Alejandro; Torrens-Fontanals, Mariona; Stepniewski, Tomasz Maciej; Grau-Exposito, Judith; Perea, David; Ayinampudi, Vikram; Waldhoer, Maria; Zimmermann, Mirjam; Buzon, Maria J.; Genesca, Meritxell; Selent, Jana
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
DOI /
10.3390/ijms222413592
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1
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Electron Paramagnetic Resonance Gives Evidence for the Presence of Type 1 Gonadotropin-Releasing Hormone Receptor (GnRH-R) in Subdomains of Lipid Rafts
Koklic, Tilen; Hrovat, Alenka; Guixa-Gonzalez, Ramon; Rodriguez-Espigares, Ismael; Navio, Damaris; Frangez, Robert; Ursic, Matjaz; Kubale, Valentina; Plemenitas, Ana; Selent, Jana; Sentjurc, Marjeta; Vrecl, Milka
MOLECULES
(2021)
DOI /
10.3390/molecules26040973
Gold DOAJ, Green published
Mentions
2
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Synthesis, molecular modelling studies and biological evaluation of new oxoeicosanoid receptor 1 agonists
Maciej Stepniewski, Tomasz; Torrens-Fontanals, Mariona; Rodriguez-Espigares, Ismael; Giorgino, Toni; Primdahl, Karoline G.; Vik, Anders; Stenstrom, Yngve; Selent, Jana; Hansen, Trond Vidar
BIOORGANIC & MEDICINAL CHEMISTRY
0968-0896 (2018)
DOI /
10.1016/j.bmc.2018.05.036
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2
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Membrane cholesterol effect on the 5-HT2A receptor: Insights into the lipid-induced modulation of an antipsychotic drug target
Manuel Ramirez-Anguita, Juan; Rodriguez-Espigares, Ismael; Guixa-Gonzalez, Ramon; Bruno, Agostino; Torrens-Fontanals, Mariona; Varela-Rial, Alejandro; Selent, Jana
BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY
0885-4513 (2018)
DOI /
10.1002/bab.1608
