Biology & Biochemistry

Listando 40 trabajos del autor/autora 38

Lista de trabajos en el área Biology & Biochemistry

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Article Structural stability of SARS-CoV-2 3CLpro and identification of quercetin as an inhibitor by experimental screening Abian, Olga; Ortega-Alarcon, David; Jimenez-Alesanco, Ana; Ceballos-Laita, Laura; Vega, Sonia; Reyburn, Hugh T.; Rizzuti, Bruno; Velazquez-Campoy, Adrian INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 0141-8130 (2020) DOI / 10.1016/j.ijbiomac.2020.07.235 Bronze, Green published

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Article Seleno-Functionalization of Quercetin Improves the Non-Covalent Inhibition of M-pro and Its Antiviral Activity in Cells against SARS-CoV-2 Mangiavacchi, Francesca; Botwina, Pawel; Menichetti, Elena; Bagnoli, Luana; Rosati, Ornelio; Marini, Francesca; Fonseca, Sergio F.; Abenante, Laura; Alves, Diego; Dabrowska, Agnieszka; Kula-Pacurar, Anna; Ortega-Alarcon, David; Jimenez-Alesanco, Ana; Cebal INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 1661-6596 (2021) DOI / 10.3390/ijms22137048 Gold, Green published

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Article Inhibition of the PP2A activity by the histone chaperone ANP32B is long-range allosterically regulated by respiratory cytochrome c Rivero-Rodriguez, Francisco; Diaz-Quintana, Antonio; Velazquez-Cruz, Alejandro; Gonzalez-Arzola, Katiuska; Gavilan, Maria P.; Velazquez-Campoy, Adrian; Rios, Rosa M.; De la Rosa, Miguel A.; Diaz-Moreno, Irene REDOX BIOLOGY 2213-2317 (2021) DOI / 10.1016/j.redox.2021.101967 Gold DOAJ, Green published

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Article Identification of a Drug Targeting an Intrinsically Disordered Protein Involved in Pancreatic Adenocarcinoma Neira, Jose L.; Bintz, Jennifer; Arruebo, Maria; Rizzuti, Bruno; Bonacci, Thomas; Vega, Sonia; Lanas, Angel; Velazquez-Campoy, Adrian; Iovanna, Juan L.; Abian, Olga SCIENTIFIC REPORTS 2045-2322 (2017) DOI / 10.1038/srep39732 Green published, Gold

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Article Unprecedented pathway of reducing equivalents in a diflavin-linked disulfide oxidoreductase Buey, Ruben M.; Arellano, Juan B.; Lopez-Maury, Luis; Galindo-Trigo, Sergio; Velazquez-Campoy, Adrian; Revuelta, Jose L.; de Pereda, Jose M.; Florencio, Francisco J.; Schurmann, Peter; Buchanan, Bob B.; Balsera, Monica PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 0027-8424 (2017) DOI / 10.1073/pnas.1713698114 Green published, Bronze

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Article Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase Bellin, Leo; Del Cano-Ochoa, Francisco; Velazquez-Campoy, Adrian; Moehlmann, Torsten; Ramon-Maiques, Santiago NATURE COMMUNICATIONS (2021) DOI / 10.1038/s41467-021-21165-9 Green published, Gold

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Article Rutin Is a Low Micromolar Inhibitor of SARS-CoV-2 Main Protease 3CLpro: Implications for Drug Design of Quercetin Analogs Rizzuti, Bruno; Grande, Fedora; Conforti, Filomena; Jimenez-Alesanco, Ana; Ceballos-Laita, Laura; Ortega-Alarcon, David; Vega, Sonia; Reyburn, Hugh T.; Abian, Olga; Velazquez-Campoy, Adrian BIOMEDICINES (2021) DOI / 10.3390/biomedicines9040375 Green published, Gold

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Article Molecular Context-Dependent Effects Induced by Rett Syndrome-Associated Mutations in MeCP2 Ortega-Alarcon, David; Claveria-Gimeno, Rafael; Vega, Sonia; Jorge-Torres, Olga C.; Esteller, Manel; Abian, Olga; Velazquez-Campoy, Adrian BIOMOLECULES (2020) DOI / 10.3390/biom10111533 Gold, Green published

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Article DD04107-Derived neuronal exocytosis inhibitor peptides: Evidences for synaptotagmin-1 as a putative target Butron, Daniel; Zamora-Carreras, Hector; Devesa, Isabel; Trevino, Miguel A.; Abian, Olga; Velazquez-Campoy, Adrian; Bonache, M. Angeles; Lagartera, Laura; Martin-Martinez, Mercedes; Gonzalez-Rodriguez, Sara; Baamonde, Ana; Fernandez-Carvajal, Asia; Ferrer- BIOORGANIC CHEMISTRY 0045-2068 (2021) DOI / 10.1016/j.bioorg.2021.105231

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Article The intervening domain from MeCP2 enhances the DNA affinity of the methyl binding domain and provides an independent DNA interaction site Claveria-Gimeno, Rafael; Lanuza, Pilar M.; Morales-Chueca, Ignacio; Jorge-Torres, Olga C.; Vega, Sonia; Abian, Olga; Esteller, Manel; Velazquez-Campoy, Adrian SCIENTIFIC REPORTS 2045-2322 (2017) DOI / 10.1038/srep41635 Green published, Gold, Green submitted

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Article Mechanism of the allosteric activation of the ClpP protease machinery by substrates and active-site inhibitors Felix, Jan; Weinhaupl, Katharina; Chipot, Christophe; Dehez, Francois; Hessel, Audrey; Gauto, Diego F.; Morlot, Cecile; Abian, Olga; Gutsche, Irina; Velazquez-Campoy, Adrian; Schanda, Paul; Fraga, Hugo SCIENCE ADVANCES 2375-2548 (2019) DOI / 10.1126/sciadv.aaw3818 Green published, Green submitted, Gold

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Article AFFINImeter: A software to analyze molecular recognition processes from experimental data Pineiro, Angel; Munoz, Eva; Sabin, Juan; Costas, Miguel; Bastos, Margarida; Velazquez-Campoy, Adrian; Garrido, Pablo F.; Dumas, Philippe; Ennifar, Eric; Garcia-Rio, Luis; Rial, Javier; Perez, Daniel; Fraga, Patricia; Rodriguez, Aurelio; Cotelo, Carmen ANALYTICAL BIOCHEMISTRY 0003-2697 (2019) DOI / 10.1016/j.ab.2019.02.031

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Article Selective Targeting of Human and Animal Pathogens of the Helicobacter Genus by Flavodoxin Inhibitors: Efficacy, Synergy, Resistance and Mechanistic Studies Salillas, Sandra; Galano-Frutos, Juan Jose; Mahia, Alejandro; Maity, Ritwik; Conde-Gimenez, Maria; Anoz-Carbonell, Ernesto; Berlamont, Helena; Velazquez-Campoy, Adrian; Touati, Eliette; Mamat, Uwe; Schaible, Ulrich E.; Galvez, Jose A.; Diaz-de-Villegas, Ma INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 1661-6596 (2021) DOI / 10.3390/ijms221810137 Green published, Gold

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Article Tolcapone, a potent aggregation inhibitor for the treatment of familial leptomeningeal amyloidosis Pinheiro, Francisca; Varejao, Nathalia; Esperante, Sebastian; Santos, Jaime; Velazquez-Campoy, Adrian; Reverter, David; Pallares, Irantzu; Ventura, Salvador FEBS JOURNAL 1742-464X (2020) DOI / 10.1111/febs.15339 Green accepted

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Article 2-oxoglutarate modulates the affinity of FurA for the ntcA promoter in Anabaena sp. PCC 7120 Guio, Jorge; Saresa-Buisan, Cristina; Velazquez-Campoy, Adrian; Teresa Bes, Maria; Fillat, Maria F.; Luisa Peleato, Maria; Sevilla, Emma FEBS LETTERS 0014-5793 (2019) DOI / 10.1002/1873-3468.13610 Green accepted, Bronze

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Article Stabilization Effect of Intrinsically Disordered Regions on Multidomain Proteins: The Case of the Methyl-CpG Protein 2, MeCP2 Ortega-Alarcon, David; Claveria-Gimeno, Rafael; Vega, Sonia; Jorge-Torres, Olga C.; Esteller, Manel; Abian, Olga; Velazquez-Campoy, Adrian BIOMOLECULES (2021) DOI / 10.3390/biom11081216 Gold, Green published

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Article Influence of the disordered domain structure of MeCP2 on its structural stability and dsDNA interaction Ortega-Alarcon, David; Claveria-Gimeno, Rafael; Vega, Sonia; Jorge-Torres, Olga C.; Esteller, Manel; Abian, Olga; Velazquez-Campoy, Adrian INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 0141-8130 (2021) DOI / 10.1016/j.ijbiomac.2021.01.206 Green published

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Review Targeting intrinsically disordered proteins involved in cancer Santofimia-Castano, Patricia; Rizzuti, Bruno; Xia, Yi; Abian, Olga; Peng, Ling; Velazquez-Campoy, Adrian; Neira, Jose L.; Iovanna, Juan CELLULAR AND MOLECULAR LIFE SCIENCES 1420-682X (2020) DOI / 10.1007/s00018-019-03347-3 Gold other, Green published

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Article The nuclear localization sequence of the epigenetic factor RYBP binds to human importin alpha 3 Neira, Jose L.; Jimenez-Alesanco, Ana; Rizzuti, Bruno; Velazquez-Campoy, Adrian BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS 1570-9639 (2021) DOI / 10.1016/j.bbapap.2021.140670

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Article Structural insights into the ability of nucleoplasmin to assemble and chaperone histone octamers for DNA deposition Franco, Aitor; Arranz, Rocio; Fernandez-Rivero, Noelia; Velazquez-Campoy, Adrian; Martin-Benito, Jaime; Segura, Joan; Prado, Adelina; Valpuesta, Jose M.; Muga, Arturo SCIENTIFIC REPORTS 2045-2322 (2019) DOI / 10.1038/s41598-019-45726-7 Green published, Gold other

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Article Human riboflavin kinase: Species-specific traits in the biosynthesis of the FMN cofactor Anoz-Carbonell, Ernesto; Rivero, Maribel; Polo, Victor; Velazquez-Campoy, Adrian; Medina, Milagros FASEB JOURNAL 0892-6638 (2020) DOI / 10.1096/fj.202000566r

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Letter A New Member of the Thioredoxin Reductase Family from Early Oxygenic Photosynthetic Organisms Buey, Ruben M.; Galindo-Trigo, Sergio; Lopez-Maury, Luis; Velazquez-Campoy, Adrian; Luis Revuelta, Jose; Javier Florencio, F.; de Pereda, Jose M.; Schurmann, Peter; Buchanan, Bob B.; Balsera, Monica MOLECULAR PLANT 1674-2052 (2017) DOI / 10.1016/j.molp.2016.06.019 Green accepted, Bronze

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Article Dendrimers as Competitors of Protein-Protein Interactions of the Intrinsically Disordered Nuclear Chromatin Protein NUPR1 Neira, Jose L.; Correa, Juan; Rizzuti, Bruno; Santofimia-Castano, Patricia; Abian, Olga; Velazquez-Campoy, Adrian; Fernandez-Megia, Eduardo; Iovanna, Juan L. BIOMACROMOLECULES 1525-7797 (2019) DOI / 10.1021/acs.biomac.9b00378

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Article Kinetics and thermodynamics of the protein-ligand interactions in the riboflavin kinase activity of the FAD synthetase from Corynebacterium ammoniagenes Sebastian, Maria; Serrano, Ana; Velazquez-Campoy, Adrian; Medina, Milagros SCIENTIFIC REPORTS 2045-2322 (2017) DOI / 10.1038/s41598-017-07875-5 Gold DOAJ, Green published

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Article Structural basis of mitochondrial dysfunction in response to cytochrome c phosphorylation at tyrosine 48 Moreno-Beltran, Blas; Guerra-Castellano, Alejandra; Diaz-Quintana, Antonio; Del Conte, Rebecca; Garcia-Maurino, Sofia M.; Diaz-Moreno, Sofia; Gonzalez-Arzola, Katiuska; Santos-Ocana, Carlos; Velazquez-Campoy, Adrian; De la Rosa, Miguel A.; Turano, Paola; D PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 0027-8424 (2017) DOI / 10.1073/pnas.1618008114 Green published, Green submitted, Hybrid

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Article Fluorescence Liquid Biopsy for Cancer Detection Is Improved by Using Cationic Dendronized Hyperbranched Polymer Morcuende-Ventura, Violeta; Hermoso-Duran, Sonia; Abian-Franco, Natalia; Pazo-Cid, Roberto; Ojeda, Jorge L.; Vega, Sonia; Sanchez-Gracia, Oscar; Velazquez-Campoy, Adrian; Sierra, Teresa; Abian, Olga INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 1661-6596 (2021) DOI / 10.3390/ijms22126501 Gold, Green published

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Article Macromolecular interactions in vitro, comparing classical and novel approaches Velours, Christophe; Aumont-Nicaise, Magali; Uebel, Stephan; England, Patrick; Velazquez-Campoy, Adrian; Stroebel, David; Bec, Guillaume; Soule, Pierre; Quetard, Christophe; Ebel, Christine; Roussel, Alain; Charbonnier, Jean-Baptiste; Varela, Paloma Fernan EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS 0175-7571 (2021) DOI / 10.1007/s00249-021-01517-5

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Article A Phosphorylation-Induced Switch in the Nuclear Localization Sequence of the Intrinsically Disordered NUPR1 Hampers Binding to Importin Neira, Jose L.; Rizzuti, Bruno; Jimenez-Alesanco, Ana; Palomino-Schatzlein, Martina; Abian, Olga; Velazquez-Campoy, Adrian; Iovanna, Juan L. BIOMOLECULES (2020) DOI / 10.3390/biom10091313 Green published, Gold

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Article Histone chaperone activity of Arabidopsis thaliana NRP1 is blocked by cytochrome c Gonzalez-Arzola, Katiuska; Diaz-Quintana, Antonio; Rivero-Rodriguez, Francisco; Velazquez-Campoy, Adrian; De la Rosa, Miguel A.; Diaz-Moreno, Irene NUCLEIC ACIDS RESEARCH 0305-1048 (2017) DOI / 10.1093/nar/gkw1215 Green published, Gold