Clinical Medicine
Listando 40 trabajos del autor/autora 38
Lista de trabajos en el área Clinical Medicine
Mentions
120
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0
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52
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0
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Article
The European Society for Medical Oncology (ESMO) Precision Medicine Glossary
Yates, L. R.; Seoane, J.; Le Tourneau, C.; Siu, L. L.; Marais, R.; Michiels, S.; Soria, J. C.; Campbell, P.; Normanno, N.; Scarpa, A.; Reis-Filho, J. S.; Rodon, J.; Swanton, C.; Andre, F.
ANNALS OF ONCOLOGY
0923-7534 (2018)
DOI /
10.1093/annonc/mdx707
Bronze
Mentions
1
Twitter
0
Wikipedia
53
News
0
Policy
Review
Targeting the fibroblast growth factor receptor 2 in gastric cancer: promise or pitfall?
Hierro, C.; Alsina, M.; Sanchez, M.; Serra, V.; Rodon, J.; Tabernero, J.
ANNALS OF ONCOLOGY
0923-7534 (2017)
DOI /
10.1093/annonc/mdx081
Bronze
Mentions
217
Twitter
0
Wikipedia
61
News
0
Policy
Article
Genomic and transcriptomic profiling expands precision cancer medicine: the WINTHER trial
Rodon, Jordi; Soria, Jean-Charles; Berger, Raanan; Miller, Wilson H.; Rubin, Eitan; Kugel, Aleksandra; Tsimberidou, Apostolia; Saintigny, Pierre; Ackerstein, Aliza; Brana, Irene; Loriot, Yohann; Afshar, Mohammad; Miller, Vincent; Wunder, Fanny; Bresson, Ca
NATURE MEDICINE
1078-8956 (2019)
DOI /
10.1038/s41591-019-0424-4
Green accepted
Mentions
306
Twitter
0
Wikipedia
29
News
0
Policy
Article
HER kinase inhibition in patients with HER2-and HER3-mutant cancers
Hyman, David M.; Piha-Paul, Sarina A.; Won, Helen; Rodon, Jordi; Saura, Cristina; Shapiro, Geoffrey I.; Juric, Dejan; Quinn, David I.; Moreno, Victor; Doger, Bernard; Mayer, Ingrid A.; Boni, Valentina; Calvo, Emiliano; Loi, Sherene; Lockhart, Albert C.; Er
NATURE
0028-0836 (2018)
DOI /
10.1038/nature25475
Green accepted
Mentions
282
Twitter
1
Wikipedia
8
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0
Policy
Article
Actively personalized vaccination trial for newly diagnosed glioblastoma
Hilf, Norbert; Kuttruff-Coqui, Sabrina; Frenzel, Katrin; Bukur, Valesca; Stevanovic, Stefan; Gouttefangeas, Cecile; Platten, Michael; Tabatabai, Ghazaleh; Dutoit, Valerie; van der Burg, Sjoerd H.; Straten, Per Thor; Martinez-Ricarte, Francisco; Ponsati, Be
NATURE
0028-0836 (2019)
DOI /
10.1038/s41586-018-0810-y
Green accepted
Mentions
152
Twitter
0
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5
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0
Policy
Letter
Support systems to guide clinical decision-making in precision oncology: The Cancer Core Europe Molecular Tumor Board Portal
Tamborero, David; Dienstmann, Rodrigo; Rachid, Maan Haj; Boekel, Jorrit; Baird, Richard; Brana, Irene; de Petris, Luigi; Yachnin, Jeffrey; Massard, Christophe; Opdam, Frans L.; Schlenk, Richard; Vernieri, Claudio; Garralda, Elena; Masucci, Michele; Villalo
NATURE MEDICINE
1078-8956 (2020)
DOI /
10.1038/s41591-020-0969-2
Mentions
5
Twitter
0
Wikipedia
9
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0
Policy
Article
Phase I, First-in-Human Study of the Probody Therapeutic CX-2029 in Adults with Advanced Solid Tumor Malignancies
Johnson, Melissa; El-Khoueiry, Anthony; Hafez, Navid; Lakhani, Nehal; Mamdani, Hirva; Rodon, Jordi; Sanborn, Rachel E.; Garcia-Corbacho, Javier; Boni, Valentina; Stroh, Mark; Hannah, Alison L.; Wang, Song; Castro, Henry; Spira, Alexander
CLINICAL CANCER RESEARCH
(2021)
DOI /
10.1158/1078-0432.ccr-21-0194
Mentions
52
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0
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2
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0
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Article
A CT-based Radiomics Signature Is Associated with Response to Immune Checkpoint Inhibitors in Advanced Solid Tumors
Ligero, Marta; Garcia-Ruiz, Alonso; Viaplana, Cristina; Villacampa, Guillermo; Raciti, Maria, V; Landa, Jaid; Matos, Ignacio; Martin-Liberal, Juan; Ochoa-de-Olza, Maria; Hierro, Cinta; Mateo, Joaquin; Gonzalez, Macarena; Morales-Barrera, Rafael; Suarez, Cr
RADIOLOGY
0033-8419 (2021)
DOI /
10.1148/radiol.2021200928
Mentions
55
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0
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2
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0
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Article
BRAF Inhibition in BRAF(V600)-Mutant Gliomas: Results From the VE-BASKET Study
Kaley, Thomas; Touat, Mehdi; Subbiah, Vivek; Hollebecque, Antoine; Rodon, Jordi; Lockhart, A. Craig; Keedy, Vicki; Bielle, Franck; Hofheinz, Ralf-Dieter; Joly, Florence; Blay, Jean-Yves; Chau, Ian; Puzanov, Igor; Raje, Noopur S.; Wolf, Jurgen; DeAngelis, L
JOURNAL OF CLINICAL ONCOLOGY
0732-183X (2018)
DOI /
10.1200/jco.2018.78.9990
Gold other, Green published
Mentions
68
Twitter
0
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0
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0
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Article
Capturing Hyperprogressive Disease with Immune-Checkpoint Inhibitors Using RECIST 1.1 Criteria
Matos, Ignacio; Martin-Liberal, Juan; Garcia-Ruiz, Alonso; Hierro, Cinta; Ochoa de Olza, Maria; Viaplana, Cristina; Azaro, Analia; Vieito, Maria; Brana, Irene; Mur, Gemma; Ros, Javier; Mateos, Jose; Villacampa, Guillermo; Berche, Roger; Oliveira, Mafalda;
CLINICAL CANCER RESEARCH
1078-0432 (2020)
DOI /
10.1158/1078-0432.ccr-19-2226
Bronze
Mentions
35
Twitter
0
Wikipedia
3
News
0
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Article
Phosphatidylinositol 3-Kinase -Selective Inhibition With Alpelisib (BYL719) in PIK3CA-Altered Solid Tumors: Results From the First-in-Human Study
Juric, Dejan; Rodon, Jordi; Tabernero, Josep; Janku, Filip; Burris, Howard A.; Schellens, Jan H. M.; Middleton, Mark R.; Berlin, Jordan; Schuler, Martin; Gil-Martin, Marta; Rugo, Hope S.; Seggewiss-Bernhardt, Ruth; Huang, Alan; Bootle, Douglas; Demanse, Da
JOURNAL OF CLINICAL ONCOLOGY
0732-183X (2018)
DOI /
10.1200/jco.2017.72.7107
Green published, Green accepted
Mentions
43
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0
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0
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0
Policy
Article
Evolving Landscape of Molecular Prescreening Strategies for Oncology Early Clinical Trials
Dienstmann, Rodrigo; Garralda, Elena; Aguilar, Susana; Sala, Gemma; Viaplana, Cristina; Ruiz-Pace, Fiorella; Gonzalez-Zorelle, Jenifer; Grazia LoGiacco, Deborah; Ogbah, Zighereda; Ramos Masdeu, Laia; Mancuso, Francesco; Fasani, Roberta; Jimenez, Jose; Mart
JCO PRECISION ONCOLOGY
(2020)
DOI /
10.1200/po.19.00398
Gold other, Green published
Mentions
30
Twitter
0
Wikipedia
0
News
0
Policy
Review
The expanding role of immunotherapy
Martin-Liberal, Juan; Ochoa de Olza, Maria; Hierro, Cinta; Gros, Alena; Rodon, Jordi; Tabernero, Josep
CANCER TREATMENT REVIEWS
0305-7372 (2017)
DOI /
10.1016/j.ctrv.2017.01.008
Mentions
39
Twitter
0
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0
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0
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Article
Phase I prognostic online (PIPO): A web tool to improve patient selection for oncology early phase clinical trials
Matos, Ignacio; Villacampa, Guillermo; Hierro, Cinta; Martin-Liberal, Juan; Berche, Roger; Pedrola, Anna; Brana, Irene; Azaro, Analia; Vieito, Maria; Saavedra, Omar; Gardeazabal, Itziar; Hernando-Calvo, Alberto; Alonso, Guzman; Galvao, Vladimir; de Olza, M
EUROPEAN JOURNAL OF CANCER
0959-8049 (2021)
DOI /
10.1016/j.ejca.2021.05.040
Hybrid
Mentions
28
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0
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0
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0
Policy
Article
Alpelisib Plus Fulvestrant in PIK3CA-Altered and PIK3CA-Wild-Type Estrogen Receptor-Positive Advanced Breast Cancer A Phase 1b Clinical Trial
Juric, Dejan; Janku, Filip; Rodon, Jordi; Burris, Howard A.; Mayer, Ingrid A.; Schuler, Martin; Seggewiss-Bernhardt, Ruth; Gil-Martin, Marta; Middleton, Mark R.; Baselga, Jose; Bootle, Douglas; Demanse, David; Blumenstein, Lars; Schumacher, Karl; Huang, Al
JAMA ONCOLOGY
2374-2437 (2019)
DOI /
10.1001/jamaoncol.2018.4475
Green published, Bronze
Mentions
18
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0
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0
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0
Policy
Article
First-in-Human Phase I Study of MP0250, a First-in-Class DARPin Drug Candidate Targeting VEGF and HGF, in Patients With Advanced Solid Tumors
Baird, Richard D.; Linossi, Constanza; Middleton, Mark; Lord, Simon; Harris, Adrian; Rodon, Jordi; Zitt, Christof; Fiedler, Ulrike; Dawson, Keith M.; Leupin, Nicolas; Stumpp, Michael T.; Harstrick, Andreas; Azaro, Analia; Fischer, Stefanie; Omlin, Aurelius
JOURNAL OF CLINICAL ONCOLOGY
0732-183X (2021)
DOI /
10.1200/jco.20.00596
Green published, Gold other
Mentions
25
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0
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0
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0
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Article
First-in-Human Phase I Study to Evaluate the Brain-Penetrant PI3K/mTOR Inhibitor GDC-0084 in Patients with Progressive or Recurrent High-Grade Glioma
Wen, Patrick Y.; Cloughesy, Timothy F.; Olivero, Alan G.; Morrissey, Kari M.; Wilson, Timothy R.; Lu, Xuyang; Mueller, Lars U.; Coimbra, Alexandre F.; Ellingson, Benjamin M.; Gerstner, Elizabeth; Lee, Eudocia Q.; Rodon, Jordi
CLINICAL CANCER RESEARCH
1078-0432 (2020)
DOI /
10.1158/1078-0432.ccr-19-2808
Green published
Mentions
13
Twitter
0
Wikipedia
0
News
0
Policy
Article
Clinical activity and safety of atezolizumab in patients with recurrent glioblastoma
Lukas, Rimas V.; Rodon, Jordi; Becker, Kevin; Wong, Eric T.; Shih, Kent; Touat, Mehdi; Fasso, Marcella; Osborne, Stuart; Molinero, Luciana; O'Hear, Carol; Grossman, William; Baehring, Joachim
JOURNAL OF NEURO-ONCOLOGY
0167-594X (2018)
DOI /
10.1007/s11060-018-2955-9
Mentions
11
Twitter
0
Wikipedia
0
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0
Policy
Article
Phase 2 study of buparlisib (BKM120), a pan-class I PI3K inhibitor, in patients with metastatic triple-negative breast cancer
Garrido-Castro, Ana C.; Saura, Cristina; Barroso-Sousa, Romualdo; Guo, Hao; Ciruelos, Eva; Bermejo, Begona; Gavila, Joaquin; Serra, Violeta; Prat, Aleix; Pare, Laia; Celiz, Pamela; Villagrasa, Patricia; Li, Yisheng; Savoie, Jennifer; Xu, Zhan; Arteaga, Car
BREAST CANCER RESEARCH
1465-542X (2020)
DOI /
10.1186/s13058-020-01354-y
Gold DOAJ, Green published
Mentions
9
Twitter
0
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0
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0
Policy
Review
New clinical trial designs in the era of precision medicine
Garralda, Elena; Dienstmann, Rodrigo; Piris-Gimenez, Alejandro; Brana, Irene; Rodon, Jordi; Tabernero, Josep
MOLECULAR ONCOLOGY
1574-7891 (2019)
DOI /
10.1002/1878-0261.12465
Gold DOAJ, Green published
Mentions
1
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0
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0
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0
Policy
Article
First-in human, phase 1, dose-escalation pharmacokinetic and pharmacodynamic study of the oral dual PI3K and mTORC1/2 inhibitor PQR309 in patients with advanced solid tumors (SAKK 67/13)
Wicki, Andreas; Brown, Nicholas; Xyrafas, Alexandros; Bize, Vincent; Hawle, Hanne; Berardi, Simona; Cmiljanovic, Natasa; Cmiljanovic, Vladimir; Stumm, Michael; Dimitrijevic, Sasa; Herrmann, Richard; Pretre, Vincent; Ritschard, Reto; Tzankov, Alexandar; Hes
EUROPEAN JOURNAL OF CANCER
0959-8049 (2018)
DOI /
10.1016/j.ejca.2018.03.012
Mentions
4
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0
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0
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0
Policy
Review
Clinical research in small genomically stratified patient populations
Martin-Liberal, J.; Rodon, J.
EUROPEAN JOURNAL OF CANCER
0959-8049 (2017)
DOI /
10.1016/j.ejca.2017.05.008
Mentions
9
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0
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0
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0
Policy
Article
Multiparametric MR-PET Imaging Predicts Pharmacokinetics and Clinical Response to GDC-0084 in Patients with Recurrent High-Grade Glioma
Ellingson, Benjamin M.; Yao, Jingwen; Raymond, Catalina; Nathanson, David A.; Chakhoyan, Ararat; Simpson, Jeremy; Garner, James S.; Olivero, Alan G.; Mueller, Lars U.; Rodon, Jordi; Gerstner, Elizabeth; Cloughesy, Timothy F.; Wen, Patrick Y.
CLINICAL CANCER RESEARCH
1078-0432 (2020)
DOI /
10.1158/1078-0432.ccr-19-3817
Bronze, Green accepted
Mentions
5
Twitter
0
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0
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0
Policy
Article
Notch pathway inhibition with LY3039478 in soft tissue sarcoma and gastrointestinal stromal tumours
Mir, Olivier; Azaro, Analia; Merchan, Jaime; Chugh, Rashmi; Trent, Jonathan; Rodon, Jordi; Ohnmacht, Ute; Diener, J. T.; Smith, Claire; Yuen, Eunice; Oakley, Gerard Joseph, III; Le Cesne, Axel; Soria, Jean-Charles; Benhadji, Karim A.; Massard, Christophe
EUROPEAN JOURNAL OF CANCER
0959-8049 (2018)
DOI /
10.1016/j.ejca.2018.08.012
Mentions
5
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0
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0
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0
Policy
Article
First-in-human phase I study of oral S49076, a unique MET/AXL/FGFR inhibitor, in advanced solid tumours
Rodon, Jordi; Postel-Vinay, Sophie; Hollebecque, Antoine; Nuciforo, Paolo; Azaro, Analia; Cattan, Valerie; Marfai, Lucie; Sudey, Isabelle; Brendel, Karl; Delmas, Audrey; Malasse, Stephanie; Soria, Jean-Charles
EUROPEAN JOURNAL OF CANCER
0959-8049 (2017)
DOI /
10.1016/j.ejca.2017.05.007
Mentions
4
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0
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0
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0
Policy
Article
Phase I Trial of a Tablet Formulation of Pilaralisib, a Pan-Class I PI3K Inhibitor, in Patients with Advanced Solid Tumors
Edelman, Gerald; Rodon, Jordi; Lager, Joanne; Castell, Christelle; Jiang, Jason; Van Allen, Eliezer M.; Wagle, Nikhil; Lindeman, Neal I.; Sholl, Lynette M.; Shapiro, Geoffrey I.
ONCOLOGIST
1083-7159 (2018)
DOI /
10.1634/theoncologist.2017-0691
Green published, Bronze
Mentions
2
Twitter
0
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0
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0
Policy
Article
Phase 1 study of single-agent WNT974, a first-in-class Porcupine inhibitor, in patients with advanced solid tumours
Rodon, Jordi; Argiles, Guillem; Connolly, Roisin M.; Vaishampayan, Ulka; de Jonge, Maja; Garralda, Elena; Giannakis, Marios; Smith, David C.; Dobson, Jason R.; McLaughlin, Margaret E.; Seroutou, Abdelkader; Ji, Yan; Morawiak, Jennifer; Moody, Susan E.; Jan
BRITISH JOURNAL OF CANCER
0007-0920 (2021)
DOI /
10.1038/s41416-021-01389-8
Mentions
1
Twitter
0
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0
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0
Policy
Article
A first-in-human phase I study of SAR125844, a selective MET tyrosine kinase inhibitor, in patients with advanced solid tumours with MET amplification
Angevin, Eric; Spitaleri, Gianluca; Rodon, Jordi; Dotti, Katia; Isambert, Nicolas; Salvagni, Stefania; Moreno, Victor; Assadourian, Sylvie; Gomez, Corinne; Harnois, Marzia; Hollebecque, Antoine; Azaro, Analia; Hervieu, Alice; Rihawi, Karim; de Marinis, Fil
EUROPEAN JOURNAL OF CANCER
0959-8049 (2017)
DOI /
10.1016/j.ejca.2017.10.016
Gold other
Mentions
1
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0
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0
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0
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Review
Unveiling changes in the landscape of patient populations in cancer early drug development
Hierro, Cinta; Azaro, Analia; Argiles, Guillem; Elez, Elena; Gomez, Patricia; Carles, Joan; Rodon, Jordi
ONCOTARGET
1949-2553 (2017)
DOI /
10.18632/oncotarget.13258
Gold other, Green published
Mentions
2
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0
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0
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0
Policy
Article
Immuno-Oncology: The Third Paradigm in Early Drug Development
Martin-Liberal, Juan; Hierro, Cinta; Ochoa de Olza, Maria; Rodon, Jordi
TARGETED ONCOLOGY
1776-2596 (2017)
DOI /
10.1007/s11523-016-0471-4
Mentions
3
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0
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0
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0
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Article
Phase I/IIa, open-label, multicentre study to evaluate the optimal dosing and safety of ODM-203 in patients with advanced or metastatic solid tumours
Bono, Petri; Massard, Christophe; Peltola, Katriina J.; Azaro, Analia; Italiano, Antoine; Kristeleit, Rebecca S.; Curigliano, Giuseppe; Lassen, Ulrik; Arkenau, Hendrik-Tobias; Hakulinen, Pasi; Garratt, Chris; Ikonen, Tarja; Mustonen, Mika V. J.; Rodon, Jor
ESMO OPEN
(2020)
DOI /
10.1136/esmoopen-2020-001081
Gold other, Green published
Mentions
1
Twitter
0
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0
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0
Policy
Article
First-in-human study of LY3039478, an oral Notch signaling inhibitor in advanced or metastatic cancer
Massard, C.; Azaro, A.; Soria, J. -C.; Lassen, U.; Le Tourneau, C.; Sarker, D.; Smith, C.; Ohnmacht, U.; Oakley, G.; Patel, B. K. R.; Yuen, E. S. M.; Benhadji, K. A.; Rodon, J.
ANNALS OF ONCOLOGY
0923-7534 (2018)
DOI /
10.1093/annonc/mdy244
Bronze
Mentions
1
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0
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0
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0
Policy
Article
Phase 1b/2a study of galunisertib, a small molecule inhibitor of transforming growth factor-beta receptor I, in combination with standard temozolomide-based radiochemotherapy in patients with newly diagnosed malignant glioma
Wick, Antje; Desjardins, Annick; Suarez, Cristina; Forsyth, Peter; Gueorguieva, Ivelina; Burkholder, Tiana; Cleverly, Ann Louise; Estrem, Shawn T.; Wang, Shuaicheng; Lahn, Michael M.; Guba, Susan C.; Capper, David; Rodon, Jordi
INVESTIGATIONAL NEW DRUGS
0167-6997 (2020)
DOI /
10.1007/s10637-020-00910-9
Green published, Gold other
Mentions
3
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0
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0
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0
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Article
Analysis of mutant allele fractions in driver genes in colorectal cancer - biological and clinical insights
Dienstmann, Rodrigo; Elez, Elena; Argiles, Guillem; Matos, Ignacio; Sanz-Garcia, Enrique; Ortiz, Carolina; Macarulla, Teresa; Capdevila, Jaume; Alsina, Maria; Sauri, Tamara; Verdaguer, Helena; Vilaro, Marta; Ruiz-Pace, Fiorella; Viaplana, Cristina; Garcia,
MOLECULAR ONCOLOGY
1574-7891 (2017)
DOI /
10.1002/1878-0261.12099
Gold DOAJ, Green published
Mentions
1
Twitter
0
Wikipedia
0
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0
Policy
Review
Mechanisms of Resistance to PI3K Inhibitors in Cancer: Adaptive Responses, Drug Tolerance and Cellular Plasticity
Wright, Sarah Christine Elisabeth; Vasilevski, Natali; Serra, Violeta; Rodon, Jordi; Eichhorn, Pieter Johan Adam
CANCERS
(2021)
DOI /
10.3390/cancers13071538
Gold DOAJ, Green published
Mentions
1
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0
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0
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0
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Article
Hepatic safety analysis of trabectedin: results of a pharmacokinetic study with trabectedin in patients with hepatic impairment and experience from a phase 3 clinical trial
Calvo, Emiliano; Azaro, Analia; Rodon, Jordi; Dirix, Luc; Huizing, Manon; Senecal, Francis Mark; LoRusso, Patricia; Yee, Lorrin; Poggesi, Italo; de Jong, Jan; Triantos, Spyros; Park, Youn C.; Knoblauch, Roland E.; Parekh, Trilok V.; Demetri, George D.; von
INVESTIGATIONAL NEW DRUGS
0167-6997 (2018)
DOI /
10.1007/s10637-017-0546-9
Mentions
1
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0
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0
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0
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Article
A Phase Ib/II, open-label, multicenter study of INC280 (capmatinib) alone and in combination with buparlisib (BKM120) in adult patients with recurrent glioblastoma
van den Bent, Martin; Azaro, Analia; De Vos, Filip; Sepulveda, Juan; Yung, W. K. Alfred; Wen, Patrick Y.; Lassman, Andrew B.; Joerger, Markus; Tabatabai, Ghazaleh; Rodon, Jordi; Tiedt, Ralph; Zhao, Sylvia; Kirsilae, Tiina; Cheng, YI; Vicente, Sergio; Balbi
JOURNAL OF NEURO-ONCOLOGY
0167-594X (2019)
DOI /
10.1007/s11060-019-03337-2
Gold other, Green published
Mentions
1
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0
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0
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0
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Article
Phase 1 study of 2 high dose intensity schedules of the pan-Notch inhibitor crenigacestat (LY3039478) in combination with prednisone in patients with advanced or metastatic cancer
Azaro, Analia; Baldini, Capucine; Rodon, Jordi; Soria, Jean-Charles; Yuen, Eunice; Lithio, Andrew; Oakley, Gerard; Benhadji, Karim A.; Massard, Christophe
INVESTIGATIONAL NEW DRUGS
0167-6997 (2020)
DOI /
10.1007/s10637-020-00944-z
Mentions
1
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0
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0
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0
Policy
Editorial Material
Improving the Armamentarium of PI3K Inhibitors with Isoform-Selective Agents: A new Light in the Darkness
Rodon, Jordi; Tabernero, Josep
CANCER DISCOVERY
2159-8274 (2017)
DOI /
10.1158/2159-8290.cd-17-0500
Bronze
Mentions
1
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0
Wikipedia
0
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0
Policy
Article
Phase I, open-label, multicentre study of buparlisib in combination with temozolomide or with concomitant radiation therapy and temozolomide in patients with newly diagnosed glioblastoma
Wen, Patrick Yung; Rodon, Jordi A.; Mason, Warren; Beck, Joseph T.; Degroot, John; Donnet, Valerie; Mills, David; El-Hashimy, Mona; Rosenthal, Mark
ESMO OPEN
(2020)
DOI /
10.1136/esmoopen-2020-000673
Gold DOAJ, Green published
