Biology & Biochemistry
Listando 29 trabajos del autor/autora 38
Lista de trabajos en el área Biology & Biochemistry
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71
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10
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Article
A DNA methylation map of human cancer at single base-pair resolution
Vidal, E.; Sayols, S.; Moran, S.; Guillaumet-Adkins, A.; Schroeder, M. P.; Royo, R.; Orozco, M.; Gut, M.; Gut, I.; Lopez-Bigas, N.; Heyn, H.; Esteller, M.
ONCOGENE
0950-9232 (2017)
DOI /
10.1038/onc.2017.176
Green published, Gold other
Mentions
86
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0
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11
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0
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Article
Impact of DNA methylation on 3D genome structure
Buitrago, Diana; Labrador, Mireia; Arcon, Juan Pablo; Lema, Rafael; Flores, Oscar; Esteve-Codina, Anna; Blanc, Julie; Villegas, Nuria; Bellido, David; Gut, Marta; Dans, Pablo D.; Heath, Simon C.; Gut, Ivo G.; Heath, Isabelle Brun; Orozco, Modesto
NATURE COMMUNICATIONS
(2021)
DOI /
10.1038/s41467-021-23142-8
Gold DOAJ, Green published
Mentions
130
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0
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9
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0
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Article
Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease
Isabel Hernandez-Alvarez, Maria; Sebastian, David; Vives, Sara; Ivanova, Saska; Bartoccioni, Paola; Kakimoto, Pamela; Plana, Natalia; Veiga, Sonia R.; Hernandez, Vanessa; Vasconcelos, Nuno; Peddinti, Gopal; Adrover, Anna; Jove, Mariona; Pamplona, Reinald;
CELL
0092-8674 (2019)
DOI /
10.1016/j.cell.2019.04.010
Green submitted, Bronze, Green accepted
Mentions
19
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0
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14
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0
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Article
Oncogenic mutations at the EGFR ectodomain structurally converge to remove a steric hindrance on a kinase-coupled cryptic epitope
Orellana, Laura; Thorne, Amy H.; Lema, Rafael; Gustavsson, Johan; Parisian, Alison D.; Hospital, Adam; Cordeiro, Tiago N.; Bernado, Pau; Scott, Andrew M.; Brun-Heath, Isabelle; Lindahl, Erik; Cavenee, Webster K.; Furnari, Frank B.; Orozco, Modesto
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
0027-8424 (2019)
DOI /
10.1073/pnas.1821442116
Green published, Bronze, Green submitted
Mentions
23
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0
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9
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0
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Article
Repair of UV-Induced DNA Damage Independent of Nucleotide Excision Repair Is Masked by MUTYH
Mazouzi, Abdelghani; Battistini, Federica; Moser, Sarah C.; da Silva, Joana Ferreira; Wiedner, Marc; Owusu, Michel; Lardeau, Charles-Hugues; Ringler, Anna; Weil, Beatrix; Neesen, Juergen; Orozco, Modesto; Kubicek, Stefan; Loizou, Joanna I.
MOLECULAR CELL
1097-2765 (2017)
DOI /
10.1016/j.molcel.2017.10.021
Bronze
Mentions
6
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0
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9
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Changes in the free-energy landscape of p38 alpha MAP kinase through its canonical activation and binding events as studied by enhanced molecular dynamics simulations
Kuzmanic, Antonija; Sutto, Ludovico; Saladino, Giorgio; Nebreda, Angel R.; Gervasio, Francesco L.; Orozco, Modesto
ELIFE
2050-084X (2017)
DOI /
10.7554/elife.22175
Green published, Green submitted, Gold
Mentions
6
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0
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8
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0
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Article
Structural basis of a histidine-DNA nicking/joining mechanism for gene transfer and promiscuous spread of antibiotic resistance
Pluta, Radoslaw; Boer, D. Roeland; Lorenzo-Diaz, Fabian; Russi, Silvia; Gomez, Hansel; Fernandez-Lopez, Cris; Perez-Luque, Rosa; Orozco, Modesto; Espinosa, Manuel; Coll, Miquel
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
0027-8424 (2017)
DOI /
10.1073/pnas.1702971114
Bronze, Green accepted, Green published, Green submitted
Mentions
94
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0
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2
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0
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Article
Colibactin DNA-damage signature indicates mutational impact in colorectal cancer
Dziubanska-Kusibab, Paulina J.; Berger, Hilmar; Battistini, Federica; Bouwman, Britta A. M.; Iftekhar, Amina; Katainen, Riku; Cajuso, Tatiana; Crosetto, Nicola; Orozco, Modesto; Aaltonen, Lauri A.; Meyer, Thomas F.
NATURE MEDICINE
1078-8956 (2020)
DOI /
10.1038/s41591-020-0908-2
Green accepted
Mentions
110
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0
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0
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0
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Article
4D Genome Rewiring during Oncogene-Induced and Replicative Senescence
Sati, Satish; Bonev, Boyan; Szabo, Quentin; Jost, Daniel; Bensadoun, Paul; Serra, Francois; Loubiere, Vincent; Papadopoulos, Giorgio Lucio; Rivera-Mulia, Juan-Carlos; Fritsch, Lauriane; Bouret, Pauline; Castillo, David; Gelpi, Josep L., I; Orozco, Modesto;
MOLECULAR CELL
1097-2765 (2020)
DOI /
10.1016/j.molcel.2020.03.007
Green published, Gold other, Green accepted
Mentions
72
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0
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0
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0
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Article
Side chain to main chain hydrogen bonds stabilize a polyglutamine helix in a transcription factor
Escobedo, Albert; Topal, Busra; Kunze, Micha B. A.; Aranda, Juan; Chiesa, Giulio; Mungianu, Daniele; Bernardo-Seisdedos, Ganeko; Eftekharzadeh, Bahareh; Gairi, Margarida; Pierattelli, Roberta; Felli, Isabella C.; Diercks, Tammo; Millet, Oscar; Garcia, Jesu
NATURE COMMUNICATIONS
(2019)
DOI /
10.1038/s41467-019-09923-2
Green published, Gold, Green submitted
Mentions
8
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0
Wikipedia
2
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0
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Article
Probing allosteric regulations with coevolution-driven molecular simulations
Colizzi, Francesco; Orozco, Modesto
SCIENCE ADVANCES
2375-2548 (2021)
DOI /
10.1126/sciadv.abj0786
Gold, Green published
Mentions
11
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0
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0
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0
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Article
A multi-modal coarse grained model of DNA flexibility mappable to the atomistic level
Walther, Jurgen; Dans, Pablo D.; Balaceanu, Alexandra; Hospital, Adam; Bayarri, Genis; Orozco, Modesto
NUCLEIC ACIDS RESEARCH
0305-1048 (2020)
DOI /
10.1093/nar/gkaa015
Gold DOAJ, Green published
Mentions
31
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0
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0
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0
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Article
Emergence of chromatin hierarchical loops from protein disorder and nucleosome asymmetry
Sridhar, Akshay; Farr, Stephen E.; Portella, Guillem; Schlick, Tamar; Orozco, Modesto; Collepardo-Guevara, Rosana
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
0027-8424 (2020)
DOI /
10.1073/pnas.1910044117
Bronze, Green published
Mentions
10
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0
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0
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0
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Article
Nucleosome Dynamics: a new tool for the dynamic analysis of nucleosome positioning
Buitrago, Diana; Codo, Laia; Illa, Ricard; de Jorge, Pau; Battistini, Federica; Flores, Oscar; Bayarri, Genis; Royo, Romina; Del Pino, Marc; Heath, Simon; Hospital, Adam; Lluis Gelpi, Josep; Brun Heath, Isabelle; Orozco, Modesto
NUCLEIC ACIDS RESEARCH
0305-1048 (2019)
DOI /
10.1093/nar/gkz759
Gold DOAJ, Green published
Mentions
20
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0
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0
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0
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Article
Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes
Garcia-Lopez, Amparo; Tessaro, Francesca; Jonker, Hendrik R. A.; Wacker, Anna; Richter, Christian; Comte, Arnaud; Berntenis, Nikolaos; Schmucki, Roland; Hatje, Klas; Petermann, Olivier; Chiriano, Gianpaolo; Perozzo, Remo; Sciarra, Daniel; Konieczny, Piotr;
NATURE COMMUNICATIONS
(2018)
DOI /
10.1038/s41467-018-04110-1
Gold DOAJ, Green published
Mentions
14
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0
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0
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0
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Article
The Impact of the HydroxyMethylCytosine epigenetic signature on DNA structure and function
Battistini, Federica; Dans, Pablo D.; Terrazas, Montserrat; Castellazzi, Chiara L.; Portella, Guillem; Labrador, Mireia; Villegas, Nuria; Brun-Heath, Isabelle; Gonzalez, Carlos; Orozco, Modesto
PLOS COMPUTATIONAL BIOLOGY
(2021)
DOI /
10.1371/journal.pcbi.1009547
Mentions
12
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0
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0
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0
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Article
Protein disorder-to-order transition enhances the nucleosome-binding affinity of H1
Sridhar, Akshay; Orozco, Modesto; Collepardo-Guevara, Rosana
NUCLEIC ACIDS RESEARCH
0305-1048 (2020)
DOI /
10.1093/nar/gkaa285
Green published, Gold other
Mentions
9
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0
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0
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0
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Article
The static and dynamic structural heterogeneities of B-DNA: extending Calladine-Dickerson rules
Dans, Pablo D.; Balaceanu, Alexandra; Pasi, Marco; Patellis, Alessandro S.; Petkeviciute, Daiva; Walther, Jurgen; Hospital, Adam; Bayarri, Genis; Lavery, Richard; Maddocks, John H.; Orozco, Modesto
NUCLEIC ACIDS RESEARCH
0305-1048 (2019)
DOI /
10.1093/nar/gkz905
Gold DOAJ, Green published
Mentions
8
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0
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0
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0
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Article
BioExcel Building Blocks, a software library for interoperable biomolecular simulation workflows
Andrio, Pau; Hospital, Adam; Conejero, Javier; Jorda, Luis; Del Pino, Marc; Codo, Laia; Soiland-Reyes, Stian; Goble, Carole; Lezzi, Daniele; Badia, Rosa M.; Orozco, Modesto; Gelpi, Josep Ll.
SCIENTIFIC DATA
(2019)
DOI /
10.1038/s41597-019-0177-4
Green published, Gold
Mentions
10
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0
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0
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0
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Article
PMut: a web-based tool for the annotation of pathological variants on proteins, 2017 update
Lopez-Ferrando, Victor; Gazzo, Andrea; de la Cruz, Xavier; Orozco, Modesto; Gelpi, Josep L. I.
NUCLEIC ACIDS RESEARCH
0305-1048 (2017)
DOI /
10.1093/nar/gkx313
Gold DOAJ, Green published
Mentions
9
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0
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0
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0
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Article
DNA specificities modulate the binding of human transcription factor A to mitochondrial DNA control region
Cuppari, Anna; Fernandez-Millan, Pablo; Battistini, Federica; Tarres-Sole, Aleix; Lyonnais, Sebastien; Iruela, Guillermo; Ruiz-Lopez, Elena; Enciso, Yuliana; Rubio-Cosials, Anna; Prohens, Rafel; Pons, Miquel; Alfonso, Carlos; Toth, Katalin; Rivas, German;
NUCLEIC ACIDS RESEARCH
0305-1048 (2019)
DOI /
10.1093/nar/gkz406
Green published, Green submitted, Gold
Mentions
5
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0
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0
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0
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Article
Modulation of the helical properties of DNA: next-to-nearest neighbour effects and beyond
Balaceanu, Alexandra; Buitrago, Diana; Walther, Juergen; Hospital, Adam; Dans, Pablo D.; Orozco, Modesto
NUCLEIC ACIDS RESEARCH
0305-1048 (2019)
DOI /
10.1093/nar/gkz255
Gold DOAJ, Green published
Mentions
6
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0
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0
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0
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Article
VeriNA3d: an R package for nucleic acids data mining
Gallego, Diego; Darre, Leonardo; Dans, Pablo D.; Orozco, Modesto
BIOINFORMATICS
1367-4803 (2019)
DOI /
10.1093/bioinformatics/btz553
Mentions
4
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0
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0
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0
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Article
Plasticity in oligomerization, operator architecture, and DNA binding in the mode of action of a bacterial B-12-based photoreceptor
Fernandez-Zapata, Jesus; Perez-Castano, Ricardo; Aranda, Juan; Colizzi, Francesco; Carmen Polanco, Maria; Orozco, Modesto; Padmanabhan, S.; Elias-Arnanz, Montserrat
JOURNAL OF BIOLOGICAL CHEMISTRY
0021-9258 (2018)
DOI /
10.1074/jbc.ra118.004838
Green published, Gold other
Mentions
4
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0
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0
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0
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Article
Mechanism of Structural Tuning of the Hepatitis C Virus Human Cellular Receptor CD81 Large Extracellular Loop
Cunha, Eva S.; Sfriso, Pedro; Rojas, Adriana L.; Hospital, Adam; Orozco, Modesto; Abrescia, Nicola G. A.
STRUCTURE
0969-2126 (2017)
DOI /
10.1016/j.str.2016.11.003
Bronze
Mentions
2
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0
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0
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Article
Molywood: streamlining the design and rendering of molecular movies
Wieczor, Milosz; Hospital, Adam; Bayarri, Genis; Czub, Jacek; Orozco, Modesto
BIOINFORMATICS
1367-4803 (2020)
DOI /
10.1093/bioinformatics/btaa584
Green accepted
Mentions
1
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0
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0
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0
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Article
3dRS, a Web-Based Tool to Share Interactive Representations of 3D Biomolecular Structures and Molecular Dynamics Trajectories
Bayarri, Genis; Hospital, Adam; Orozco, Modesto
FRONTIERS IN MOLECULAR BIOSCIENCES
(2021)
DOI /
10.3389/fmolb.2021.726232
Green published, Gold
Mentions
2
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0
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0
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0
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Article
How B-DNA Dynamics Decipher Sequence-Selective Protein Recognition
Battistini, Federica; Hospital, Adam; Buitrago, Diana; Gallego, Diego; Dans, Pablo D.; Lluis Gelpi, Josep; Orozco, Modesto
JOURNAL OF MOLECULAR BIOLOGY
0022-2836 (2019)
DOI /
10.1016/j.jmb.2019.07.021
Green accepted
Mentions
1
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0
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0
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Article
Protein Flexibility and Synergy of HMG Domains Underlie U-Turn Bending of DNA by TFAM in Solution
Rubio-Cosials, Anna; Battistini, Federica; Gansen, Alexander; Cuppari, Anna; Bernado, Pau; Orozco, Modesto; Langowski, Joerg; Toth, Katalin; Sola, Maria
BIOPHYSICAL JOURNAL
0006-3495 (2018)
DOI /
10.1016/j.bpj.2017.11.3743
Bronze, Green published
