Clinical Medicine
Listando 87 trabajos del autor/autora 38
Lista de trabajos en el área Clinical Medicine
Mentions
208
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0
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7
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0
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Article
Intratumoral nanoplexed poly I:C BO-112 in combination with systemic anti-PD-1 for patients with anti-PD-1-refractory tumors
Marquez-Rodas, Ivan; Longo, Federico; Rodriguez-Ruiz, Maria E.; Calles, Antonio; Ponce, Santiago; Jove, Maria; Rubio-Viqueira, Belen; Luis Perez-Gracia, Jose; Gomez-Rueda, Ana; Lopez-Tarruella, Sara; Ponz-Sarvise, Mariano; Alvarez, Rosa; Soria-Rivas, Ainar
SCIENCE TRANSLATIONAL MEDICINE
1946-6234 (2020)
DOI /
10.1126/scitranslmed.abb0391
Mentions
170
Twitter
0
Wikipedia
6
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0
Policy
Article
Prophylactic TNF blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy
Perez-Ruiz, Elisabeth; Minute, Luna; Otano, Itziar; Alvarez, Maite; Carmen Ochoa, Maria; Belsue, Virginia; de Andrea, Carlos; Esperanza Rodriguez-Ruiz, Maria; Luis Perez-Gracia, Jose; Marquez-Rodas, Ivan; Llacer, Casilda; Alvarez, Martina; de Luque, Vanesa
NATURE
0028-0836 (2019)
DOI /
10.1038/s41586-019-1162-y
Gold other
Mentions
174
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0
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4
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0
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Article
Elevated serum interleukin-8 is associated with enhanced intratumor neutrophils and reduced clinical benefit of immune-checkpoint inhibitors
Schalper, Kurt A.; Carleton, Michael; Zhou, Ming; Chen, Tian; Feng, YE; Huang, Shu-Pang; Walsh, Alice M.; Baxi, Vipul; Pandya, Dimple; Baradet, Timothy; Locke, Darren; Wu, Qiuyan; Reilly, Timothy P.; Phillips, Penny; Nagineni, Venkata; Gianino, Nicole; Gu,
NATURE MEDICINE
1078-8956 (2020)
DOI /
10.1038/s41591-020-0856-x
Green accepted
Mentions
71
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0
Wikipedia
14
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0
Policy
Article
Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trial
El-Khoueiry, Anthony B.; Sangro, Bruno; Yau, Thomas; Crocenzi, Todd S.; Kudo, Masatoshi; Hsu, Chiun; Kim, Tae-You; Choo, Su-Pin; Trojan, Jorg; Welling, Theodore H., III; Meyer, Tim; Kang, Yoon-Koo; Yeo, Winnie; Chopra, Akhil; Anderson, Jeffrey; Dela Cruz,
LANCET
0140-6736 (2017)
DOI /
10.1016/s0140-6736(17)31046-2
Green accepted
Mentions
135
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0
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3
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0
Policy
Article
Neoadjuvant nivolumab modifies the tumor immune microenvironment in resectable glioblastoma
Schalper, Kurt A.; Rodriguez-Ruiz, Maria E.; Diez-Valle, Ricardo; Lopez-Janeiro, Alvaro; Porciuncula, Angelo; Idoate, Miguel A.; Inoges, Susana; de Andrea, Carlos; Lopez-Diaz de Cerio, Ascension; Tejada, Sonia; Berraondo, Pedro; Villarroel-Espindola, Franz
NATURE MEDICINE
1078-8956 (2019)
DOI /
10.1038/s41591-018-0339-5
Mentions
12
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0
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15
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0
Policy
Article
Intratumoral co-injection of the poly I:C-derivative BO-112 and a STING agonist synergize to achieve local and distant anti-tumor efficacy
Alvarez, Maite; Molina, Carmen; de Andrea, Carlos E.; Fernandez-Sendin, Myriam; Villalba, Maria; Gonzalez-Gomariz, Jose; Carmen Ochoa, Maria; Teijeira, Alvaro; Glez-Vaz, Javier; Aranda, Fernando; Sanmamed, Miguel F.; Rodriguez-Ruiz, Maria E.; Fan, Xinyi; S
JOURNAL FOR IMMUNOTHERAPY OF CANCER
(2021)
DOI /
10.1136/jitc-2021-002953
Gold, Green published
Mentions
203
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0
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2
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0
Policy
Review
Advances in immunotherapy for hepatocellular carcinoma
Sangro, Bruno; Sarobe, Pablo; Hervas-Stubbs, Sandra; Melero, Ignacio
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY
1759-5045 (2021)
DOI /
10.1038/s41575-021-00438-0
Hybrid, Green published
Mentions
29
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0
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7
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0
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Article
DNGR-1 limits Flt3L-mediated antitumor immunity by restraining tumor-infiltrating type I conventional dendritic cells
Cueto, Francisco J.; del Fresno, Carlos; Brandi, Paola; Combes, Alexis J.; Hernandez-Garcia, Elena; Sanchez-Paulete, Alfonso R.; Enamorado, Michel; Bromley, Christian P.; Gomez, Manuel J.; Conde-Garrosa, Ruth; Manes, Santos; Zelenay, Santiago; Melero, Igna
JOURNAL FOR IMMUNOTHERAPY OF CANCER
(2021)
DOI /
10.1136/jitc-2020-002054
Mentions
118
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0
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0
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0
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Review
Intratumoural administration and tumour tissue targeting of cancer immunotherapies
Melero, Ignacio; Castanon, Eduardo; Alvarez, Maite; Champiat, Stephane; Marabelle, Aurelien
NATURE REVIEWS CLINICAL ONCOLOGY
1759-4774 (2021)
DOI /
10.1038/s41571-021-00507-y
Green published, Bronze
Mentions
68
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0
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4
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0
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Article
Efficacy and Safety of Nivolumab Plus Ipilimumab in Patients With Advanced Hepatocellular Carcinoma Previously Treated With Sorafenib The CheckMate 040 Randomized Clinical Trial
Yau, Thomas; Kang, Yoon-Koo; Kim, Tae-You; El-Khoueiry, Anthony B.; Santoro, Armando; Sangro, Bruno; Melero, Ignacio; Kudo, Masatoshi; Hou, Ming-Mo; Matilla, Ana; Tovoli, Francesco; Knox, Jennifer J.; He, Aiwu Ruth; El-Rayes, Bassel F.; Acosta-Rivera, Mire
JAMA ONCOLOGY
2374-2437 (2020)
DOI /
10.1001/jamaoncol.2020.4564
Hybrid, Green published
Mentions
50
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0
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3
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0
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Article
Starting the fight in the tumor: expert recommendations for the development of human intratumoral immunotherapy (HIT-IT)
Marabelle, A.; Andtbacka, R.; Harrington, K.; Melero, I.; Leidner, R.; de Baere, T.; Robert, C.; Ascierto, P. A.; Baurain, J-F; Imperiale, M.; Rahimian, S.; Tersago, D.; Klumper, E.; Hendriks, M.; Kumar, R.; Stern, M.; Ohrling, K.; Massacesi, C.; Tchakov,
ANNALS OF ONCOLOGY
0923-7534 (2018)
DOI /
10.1093/annonc/mdy423
Green published, Gold other
Mentions
108
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0
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0
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0
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Editorial Material
For Whom the Cell Tolls? Intratumoral Treatment Links Innate and Adaptive Immunity
Marquez-Rodas, Ivan; Angela Aznar, Maria; Calles, Antonio; Melero, Ignacio
CLINICAL CANCER RESEARCH
1078-0432 (2019)
DOI /
10.1158/1078-0432.ccr-18-2690
Bronze
Mentions
29
Twitter
0
Wikipedia
3
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0
Policy
Article
Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of hepatocellular carcinoma
Greten, Tim F.; Abou-Alfa, Ghassan K.; Cheng, Ann-Lii; Duffy, Austin G.; El-Khoueiry, Anthony B.; Finn, Richard S.; Galle, Peter R.; Goyal, Lipika; He, Aiwu Ruth; Kaseb, Ahmed O.; Kelley, Robin Kate; Lencioni, Riccardo; Lujambio, Amaia; Mabry Hrones, Donna
JOURNAL FOR IMMUNOTHERAPY OF CANCER
(2021)
DOI /
10.1136/jitc-2021-002794
Green published, Gold
Mentions
14
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0
Wikipedia
5
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0
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Article
OX40 Agonist BMS-986178 Alone or in Combination With Nivolumab and/or Ipilimumab in Patients With Advanced Solid Tumors
Gutierrez, Martin; Moreno, Victor; Heinhuis, Kimberley M.; Olszanski, Anthony J.; Spreafico, Anna; Ong, Michael; Chu, Quincy; Carvajal, Richard D.; Trigo, Jose; Ochoa de Olza, Maria; Provencio, Mariano; De Vos, Filip Yves; De Braud, Filippo; Leong, Stephen
CLINICAL CANCER RESEARCH
1078-0432 (2021)
DOI /
10.1158/1078-0432.ccr-20-1830
Bronze
Mentions
5
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0
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5
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0
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Article
Antitumor efficacy and reduced toxicity using an anti-CD137 Probody therapeutic
Etxeberria, Inaki; Bolanos, Elixabet; Teijeira, Alvaro; Garasa, Saray; Yanguas, Alba; Azpilikueta, Arantza; Kavanaugh, William M.; Vasiljeva, Olga; Belvin, Marcia; Howng, Bruce; Irving, Bryan; Tipton, Kimberly; West, James; Mei, Li; Korman, Alan J.; Sega,
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
0027-8424 (2021)
DOI /
10.1073/pnas.2025930118
Mentions
90
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0
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0
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0
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Article
A Burned-Out CD8(+) T-cell Subset Expands in the Tumor Microenvironment and Curbs Cancer Immunotherapy
Sanmamed, Miguel F.; Nie, Xinxin; Desai, Shruti S.; Villaroel-Espindola, Franz; Badri, Ti; Zhao, Dejian; Kim, Anthony W.; Ji, Lan; Zhang, Tianxiang; Quinlan, Edward; Cheng, Xiaoxiao; Han, Xue; Vesely, Matthew D.; Nassar, Ala F.; Sun, Jingwei; Zhang, YU; Ki
CANCER DISCOVERY
2159-8274 (2021)
DOI /
10.1158/2159-8290.cd-20-0962
Bronze
Mentions
65
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0
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0
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0
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Article
Impaired HLA Class I Antigen Processing and Presentation as a Mechanism of Acquired Resistance to Immune Checkpoint Inhibitors in Lung Cancer
Gettinger, Scott; Choi, Jungmin; Hastings, Katherine; Truini, Anna; Datar, Ila; Sowell, Ryan; Wurtz, Anna; Dong, Weilai; Cai, Guoping; Melnick, Mary Ann; Du, Victor Y.; Schlessinger, Joseph; Goldberg, Sarah B.; Chiang, Anne; Sanmamed, Miguel F.; Melero, Ig
CANCER DISCOVERY
2159-8274 (2017)
DOI /
10.1158/2159-8290.cd-17-0593
Green accepted, Bronze
Mentions
67
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0
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0
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0
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Article
Intratumor Adoptive Transfer of IL-12 mRNA Transiently Engineered Antitumor CD8(+)T Cells
Etxeberria, Inaki; Bolanos, Elixabet; Quetglas, Jose I.; Gros, Alena; Villanueva, Alberto; Palomero, Jara; Sanchez-Paulete, Alfonso R.; Maria Piulats, Jose; Matias-Guiu, Xavier; Olivera, Irene; Ochoa, Maria C.; Labiano, Sara; Garasa, Saray; Rodriguez, Inma
CANCER CELL
1535-6108 (2019)
DOI /
10.1016/j.ccell.2019.10.006
Bronze
Mentions
52
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0
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2
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0
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Review
Paradigms on Immunotherapy Combinations with Chemotherapy
Salas-Benito, Diego; Perez-Gracia, Jose L.; Ponz-Sarvise, Mariano; Rodriguez-Ruiz, Maria E.; Martinez-Forero, Ivan; Castanon, Eduardo; Lopez-Picazo, Jose M.; Sanmamed, Miguel F.; Melero, Ignacio
CANCER DISCOVERY
2159-8274 (2021)
DOI /
10.1158/2159-8290.cd-20-1312
Mentions
7
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0
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2
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0
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Article
Results from an Integrated Safety Analysis of Urelumab, an Agonist Anti-CD137 Monoclonal Antibody
Segal, Neil H.; Logan, Theodore F.; Hodi, F. Stephen; McDermott, David; Melero, Ignacio; Hamid, Omid; Schmidt, Henrik; Robert, Caroline; Chiarion-Sileni, Vanna; Ascierto, Paolo A.; Maio, Michele; Urba, Walter J.; Gangadhar, Tara C.; Suryawanshi, Satyendra;
CLINICAL CANCER RESEARCH
1078-0432 (2017)
DOI /
10.1158/1078-0432.ccr-16-1272
Bronze, Green published
Mentions
38
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0
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0
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0
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Article
Changes in serum interleukin-8 (IL-8) levels reflect and predict response to anti-PD-1 treatment in melanoma and non-small-cell lung cancer patients
Sanmamed, M. F.; Perez-Gracia, J. L.; Schalper, K. A.; Fusco, J. P.; Gonzalez, A.; Rodriguez-Ruiz, M. E.; Onate, C.; Perez, G.; Alfaro, C.; Martin-Algarra, S.; Andueza, M. P.; Gurpide, A.; Morgado, M.; Wang, J.; Bacchiocchi, A.; Halaban, R.; Kluger, H.; Ch
ANNALS OF ONCOLOGY
0923-7534 (2017)
DOI /
10.1093/annonc/mdx190
Green published, Bronze
Mentions
36
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0
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1
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0
Policy
Review
Immunotherapy in Non-Small Cell Lung Cancer: Facts and Hopes
Doroshow, Deborah B.; Sanmamed, Miguel F.; Hastings, Katherine; Politi, Katerina; Rimm, David L.; Chen, Lieping; Melero, Ignacio; Schalper, Kurt A.; Herbst, Roy S.
CLINICAL CANCER RESEARCH
1078-0432 (2019)
DOI /
10.1158/1078-0432.ccr-18-1538
Bronze, Green accepted
Mentions
25
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0
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1
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0
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Review
Cytokines in clinical cancer immunotherapy
Berraondo, Pedro; Sanmamed, Miguel F.; Ochoa, Maria C.; Etxeberria, Inaki; Aznar, Maria A.; Luis Perez-Gracia, Jose; Rodriguez-Ruiz, Maria E.; Ponz-Sarvise, Mariano; Castanon, Eduardo; Melero, Ignacio
BRITISH JOURNAL OF CANCER
0007-0920 (2019)
DOI /
10.1038/s41416-018-0328-y
Green published, Gold other
Mentions
42
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0
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0
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0
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Article
Association of inflammatory biomarkers with clinical outcomes in nivolumab-treated patients with advanced hepatocellular carcinoma
Sangro, Bruno; Melero, Ignacio; Wadhawan, Samir; Finn, Richard S.; Abou-Alfa, Ghassan K.; Cheng, Ann-Lii; Yau, Thomas; Furuse, Junji; Park, Joong-Won; Boyd, Zachary; Tang, Hao Tracy; Shen, Yun; Tschaika, Marina; Neely, Jaclyn; El-Khoueiry, Anthony
JOURNAL OF HEPATOLOGY
0168-8278 (2020)
DOI /
10.1016/j.jhep.2020.07.026
Gold other, Green accepted
Mentions
48
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0
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0
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0
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Review
The clinical application of cancer immunotherapy based on naturally circulating dendritic cells
Bol, Kalijn F.; Schreibelt, Gerty; Rabold, Katrin; Wculek, Stefanie K.; Schwarze, Julia Katharina; Dzionek, Andrzej; Teijeira, Alvaro; Kandalaft, Lana E.; Romero, Pedro; Coukos, George; Neyns, Bart; Sancho, David; Melero, Ignacio; de Vries, I. Jolanda M.
JOURNAL FOR IMMUNOTHERAPY OF CANCER
(2019)
DOI /
10.1186/s40425-019-0580-6
Gold DOAJ, Green published
Mentions
26
Twitter
0
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0
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0
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Editorial Material
Immune Desertic Landscapes in Hepatocellular Carcinoma Shaped by beta-Catenin Activation
Berraondo, Pedro; Ochoa, Maria C.; Olivera, Irene; Melero, Ignacio
CANCER DISCOVERY
2159-8274 (2019)
DOI /
10.1158/2159-8290.cd-19-0696
Bronze
Mentions
41
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0
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0
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0
Policy
Review
Perspectives in immunotherapy: meeting report from the Immunotherapy Bridge (29-30 November, 2017, Naples, Italy)
Ascierto, Paolo A.; Brugarolas, James; Buonaguro, Luigi; Butterfield, Lisa H.; Carbone, David; Daniele, Bruno; Ferris, Robert; Fox, Bernard A.; Galon, Jerome; Gridelli, Cesare; Kaufman, Howard L.; Klebanoff, Christopher A.; Melero, Ignacio; Nathan, Paul; P
JOURNAL FOR IMMUNOTHERAPY OF CANCER
(2018)
DOI /
10.1186/s40425-018-0377-z
Gold DOAJ, Green published
Mentions
8
Twitter
0
Wikipedia
1
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0
Policy
Article
CheckMate 040 cohort 5: A phase I/II study of nivolumab in patients with advanced hepatocellular carcinoma and Child-Pugh B cirrhosis
Kudo, Masatoshi; Matilla, Ana; Santoro, Armando; Melero, Ignacio; Gracian, Antonio Cubillo; Acosta-Rivera, Mirelis; Choo, Su-Pin; El-Khoueiry, Anthony B.; Kuromatsu, Ryoko; El-Rayes, Bassel; Numata, Kazushi; Itoh, Yoshito; Di Costanzo, Francesco; Crysler,
JOURNAL OF HEPATOLOGY
0168-8278 (2021)
DOI /
10.1016/j.jhep.2021.04.047
Hybrid
Mentions
23
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0
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0
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0
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Article
An Fc-free EGFR-specific 4-1BB-agonistic Trimerbody Displays Broad Antitumor Activity in Humanized Murine Cancer Models without Toxicity
Compte, Marta; Harwood, Seandean L.; Erce-Llamazares, Ainhoa; Tapia-Galisteo, Antonio; Romero, Eduardo; Ferrer, Irene; Garrido-Martin, Eva M.; Enguita, Ana B.; Ochoa, Maria C.; Blanco, Belen; Oteo, Marta; Merino, Nekane; Nehme-Alvarez, Daniel; Hangiu, Oana
CLINICAL CANCER RESEARCH
1078-0432 (2021)
DOI /
10.1158/1078-0432.ccr-20-4625
Bronze
Mentions
2
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0
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0
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0
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Article
Anti-CD137 and PD-1/PD-L1 Antibodies En Route toward Clinical Synergy
Perez-Ruiz, Elisabeth; Etxeberria, Inaki; Rodriguez-Ruiz, Maria E.; Melero, Ignacio
CLINICAL CANCER RESEARCH
1078-0432 (2017)
DOI /
10.1158/1078-0432.ccr-17-1799
Bronze
Mentions
12
Twitter
0
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0
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0
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Review
Immunotherapy targeting 4-1BB: mechanistic rationale, clinical results, and future strategies
Chester, Cariad; Sanmamed, Miguel F.; Wang, Jun; Melero, Ignacio
BLOOD
0006-4971 (2018)
DOI /
10.1182/blood-2017-06-741041
Bronze
Mentions
4
Twitter
0
Wikipedia
1
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0
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Article
TGF beta Blockade Enhances Radiotherapy Abscopal Efficacy Effects in Combination with Anti-PD1 and Anti-CD137 Immunostimulatory Monoclonal Antibodies
Rodriguez-Ruiz, Maria E.; Rodriguez, Inmaculada; Mayorga, Lina; Labiano, Tania; Barbes, Benigno; Etxeberria, Inaki; Ponz-Sarvise, Mariano; Azpilikueta, Arantza; Bolanos, Elixabet; Sanmamed, Miguel F.; Berraondo, Pedro; Caivo, Felipe A.; Barcelos-Hoff, Mary
MOLECULAR CANCER THERAPEUTICS
1535-7163 (2019)
DOI /
10.1158/1535-7163.mct-18-0558
Bronze
Mentions
22
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0
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0
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0
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Review
Prognostic value of macrophage polarization markers in epithelial neoplasms and melanoma. A systematic review and meta-analysis
Lopez-Janeiro, Alvaro; Padilla-Ansala, Carlos; de Andrea, Carlos E.; Hardisson, David; Melero, Ignacio
MODERN PATHOLOGY
0893-3952 (2020)
DOI /
10.1038/s41379-020-0534-z
Mentions
25
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0
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0
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0
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Article
Immunotherapeutic effects of intratumoral nanoplexed poly I:C
Angela Aznar, M.; Planelles, Lourdes; Perez-Olivares, Mercedes; Molina, Carmen; Garasa, Saray; Etxeberria, Inaki; Perez, Guiomar; Rodriguez, Inmaculada; Bolanos, Elixabet; Lopez-Casas, Pedro; Rodriguez-Ruiz, Maria E.; Perez-Gracia, Jose L.; Marquez-Rodas,
JOURNAL FOR IMMUNOTHERAPY OF CANCER
(2019)
DOI /
10.1186/s40425-019-0568-2
Green published, Gold
Mentions
2
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0
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1
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0
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Article
Brachytherapy attains abscopal effects when combined with immunostimulatory monoclonal antibodies
Rodriguez-Ruiz, Maria E.; Rodriguezi, Inmaculada; Barbes, Benigno; Mayorga, Lina; Rodriguez Sanchez-Paulete, Alfonso; Ponz-Sarvise, Mariano; Luis Perez-Gracia, Jose; Melero, Ignacio
BRACHYTHERAPY
1538-4721 (2017)
DOI /
10.1016/j.brachy.2017.06.012
Mentions
20
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0
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0
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0
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Article
CD137 (4-1BB) Costimulation Modifies DNA Methylation in CD8(+) T Cell-Relevant Genes
Angela Aznar, M.; Labiano, Sara; Diaz-Lagares, Angel; Molina, Carmen; Garasa, Saray; Azpilikueta, Arantza; Etxeberria, Inaki; Sanchez-Paulete, Alfonso R.; Korman, Alan J.; Esteller, Manel; Sandoval, Juan; Melero, Ignacio
CANCER IMMUNOLOGY RESEARCH
2326-6066 (2018)
DOI /
10.1158/2326-6066.cir-17-0159
Mentions
14
Twitter
2
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0
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0
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Review
Antigen cross-presentation and T-cell cross-priming in cancer immunology and immunotherapy
Sanchez-Paulete, A. R.; Teijeira, A.; Cueto, F. J.; Garasa, S.; Perez-Gracia, J. L.; Sanchez-Arraez, A.; Sancho, D.; Melero, I.
ANNALS OF ONCOLOGY
0923-7534 (2017)
DOI /
10.1093/annonc/mdx237
Bronze
Mentions
20
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0
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0
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0
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Article
Effective cancer immunotherapy by natural mouse conventional type-1 dendritic cells bearing dead tumor antigen
Wculek, Stefanie K.; Amores-Iniesta, Joaquin; Conde-Garrosa, Ruth; Khouili, Sofia C.; Melero, Ignacio; Sancho, David
JOURNAL FOR IMMUNOTHERAPY OF CANCER
(2019)
DOI /
10.1186/s40425-019-0565-5
Green published, Gold
Mentions
15
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0
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0
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0
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Editorial Material
Cancer immunotherapy full speed ahead
Melero, I.; Navarro, B.; Teijeira, A.; Coukos, G.
ANNALS OF ONCOLOGY
0923-7534 (2017)
DOI /
10.1093/annonc/mdx739
Bronze
Mentions
16
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0
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0
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0
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Review
Safety and Tolerability of Immune Checkpoint Inhibitors (PD-1 and PD-L1) in Cancer
Baraibar, Iosune; Melero, Ignacio; Ponz-Sarvise, Mariano; Castanon, Eduardo
DRUG SAFETY
0114-5916 (2019)
DOI /
10.1007/s40264-018-0774-8
Bronze
Mentions
12
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0
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0
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0
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Editorial Material
Revisiting Interleukin-12 as a Cancer Immunotherapy Agent
Berraondo, Pedro; Etxeberria, Inaki; Ponz-Sarvise, Mariano; Melero, Ignacio
CLINICAL CANCER RESEARCH
1078-0432 (2018)
DOI /
10.1158/1078-0432.ccr-18-0381
Bronze
Mentions
11
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0
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0
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0
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Article
A randomized phase II clinical trial of dendritic cell vaccination following complete resection of colon cancer liver metastasis
Rodriguez, Javier; Castanon, Eduardo; Luis Perez-Gracia, Jose; Rodriguez, Inmaculada; Viudez, Antonio; Alfaro, Carlos; Onate, Carmen; Perez, Guiomar; Rotellar, Fernando; Inoges, Susana; Lopez-Diaz de Cerio, Ascension; Resano, Leyre; Ponz-Sarvise, Mariano;
JOURNAL FOR IMMUNOTHERAPY OF CANCER
(2018)
DOI /
10.1186/s40425-018-0405-z
Gold DOAJ, Green published
Mentions
4
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0
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0
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0
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Review
Interleukin-8 in cancer pathogenesis, treatment and follow-up
Alfaro, Carlos; Sanmamed, Miguel F.; Rodriguez-Ruiz, Maria E.; Teijeira, Alvaro; Onate, Carmen; Gonzalez, Alvaro; Ponz, Mariano; Schalper, Kurt A.; Perez-Gracia, Jose L.; Melero, Ignacio
CANCER TREATMENT REVIEWS
0305-7372 (2017)
DOI /
10.1016/j.ctrv.2017.08.004
Mentions
12
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0
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0
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0
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Editorial Material
Anti-PD1 associated fulminant myocarditis after a single pembrolizumab dose: the role of occult pre-existing autoimmunity
Martinez-Calle, Nicolas; Rodriguez-Otero, Paula; Villar, Sara; Mejias, Luis; Melero, Ignacio; Prosper, Felipe; Marinello, Patricia; Paiva, Bruno; Idoate, Miguel; San-Miguel, Jesus
HAEMATOLOGICA
0390-6078 (2018)
DOI /
10.3324/haematol.2017.185777
Gold DOAJ, Green published
Mentions
7
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0
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0
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0
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Article
Intratumoral virotherapy with 4-1BBL armed modified vaccinia Ankara eradicates solid tumors and promotes protective immune memory
Hinterberger, Maria; Giessel, Raphael; Fiore, Giovanna; Graebnitz, Fabienne; Bathke, Barbara; Wennier, Sonia; Chaplin, Paul; Melero, Ignacio; Suter, Mark; Lauterbach, Henning; Berraondo, Pedro; Hochrein, Hubertus; Medina-Echeverz, Jose
JOURNAL FOR IMMUNOTHERAPY OF CANCER
(2021)
DOI /
10.1136/jitc-2020-001586
Gold DOAJ, Green published
Mentions
16
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0
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Repurposing the yellow fever vaccine for intratumoral immunotherapy
Aznar, Maria Angela; Molina, Carmen; Teijeira, Alvaro; Rodriguez, Inmaculada; Azpilikueta, Arantza; Garasa, Saray; Sanchez-Paulete, Alfonso R.; Cordeiro, Luna; Etxeberria, Inaki; Alvarez, Maite; Rius-Rocabert, Sergio; Nistal-Villan, Estanislao; Berraondo,
EMBO MOLECULAR MEDICINE
1757-4676 (2019)
DOI /
10.15252/emmm.201910375
Green published, Gold
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2
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0
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1
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0
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Article
Heterogenous presence of neutrophil extracellular traps in human solid tumours is partially dependent on IL-8
de Andrea, Carlos E.; Ochoa, Maria Carmen; Villalba-Esparza, Maria; Teijeira, Alvaro; Schalper, Kurt A.; Abengozar-Muela, Marta; Eguren-Santamaria, Inaki; Sainz, Cristina; Sanchez-Gregorio, Sandra; Garasa, Saray; Ariz, Mikel; Ortiz-de-Solorzano, Carlos; Ro
JOURNAL OF PATHOLOGY
0022-3417 (2021)
DOI /
10.1002/path.5753
Green submitted, Hybrid
Mentions
11
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0
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0
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0
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Article
Intratumoral Immunotherapy with XCL1 and sFlt3L Encoded in Recombinant Semliki Forest Virus-Derived Vectors Fosters Dendritic Cell-Mediated T-cell Cross-Priming
Sanchez-Paulete, Alfonso R.; Teijeira, Alvaro; Quetglas, Jose I.; Rodriguez-Ruiz, Maria E.; Sanchez-Arraez, Alvaro; Labiano, Sara; Etxeberria, Inaki; Azpilikueta, Arantza; Bolanos, Elixabet; Cristina Ballesteros-Briones, Maria; Casares, Noelia; Quezada, Se
CANCER RESEARCH
0008-5472 (2018)
DOI /
10.1158/0008-5472.can-18-0933
Green accepted, Green published
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16
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0
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0
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Expression Analysis and Significance of PD-1, LAG-3, and TIM-3 in Human Non-Small Cell Lung Cancer Using Spatially Resolved and Multiparametric Single-Cell Analysis
Datar, Ila; Sanmamed, Miguel F.; Wang, Jun; Henick, Brian S.; Choi, Jungmin; Badri, Ti; Dong, Weilai; Mani, Nikita; Toki, Maria; Mejias, Luis D.; Lozano, Maria D.; Luis Perez-Gracia, Jose; Velcheti, Vamsidhar; Hellmann, MatthewD.; Gainor, Justin F.; McEach
CLINICAL CANCER RESEARCH
1078-0432 (2019)
DOI /
10.1158/1078-0432.ccr-18-4142
Green accepted, Bronze
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12
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0
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0
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0
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4-1BB (CD137) in anticancer chimeras
Melero, Ignacio; Berraondo, Pedro
JOURNAL OF EXPERIMENTAL MEDICINE
0022-1007 (2020)
DOI /
10.1084/jem.20201562
Bronze
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10
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0
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0
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CD137 Costimulation Counteracts TGF beta Inhibition of NK-cell Antitumor Function
Cabo, Mariona; Santana-Hernandez, Sara; Costa-Garcia, Marcel; Rea, Anna; Lozano-Rodriguez, Roberto; Ataya, Michelle; Balaguer, Francesc; Juan, Manel; Ochoa, Maria C.; Menendez, Silvia; Comerma, Laura; Rovira, Ana; Berraondo, Pedro; Albanell, Joan; Melero,
CANCER IMMUNOLOGY RESEARCH
2326-6066 (2021)
DOI /
10.1158/2326-6066.cir-21-0030
Mentions
7
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0
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0
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0
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Whole exome sequencing characterization of individuals presenting extreme phenotypes of high and low risk of developing tobacco-induced lung adenocarcinoma
Patino-Garcia, Ana; Guruceaga, Elizabeth; Segura, Victor; Sanchez Bayona, Rodrigo; Pilar Andueza, Maria; Tamayo Uria, Ibon; Serrano, Guillermo; Pablo Fusco, Juan; Jose Pajares, Maria; Gurpide, Alfonso; Ocon, Marimar; Sanmamed, Miguel F.; Rodriguez Ruiz, Ma
TRANSLATIONAL LUNG CANCER RESEARCH
2218-6751 (2021)
DOI /
10.21037/tlcr-20-1197
Green published, Gold other
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11
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0
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0
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0
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Combined immunotherapy encompassing intratumoral poly-ICLC, dendritic-cell vaccination and radiotherapy in advanced cancer patients
Rodriguez-Ruiz, M. E.; Perez-Gracia, J. L.; Rodriguez, I; Alfaro, C.; Onate, C.; Perez, G.; Gil-Bazo, I; Benito, A.; Inoges, S.; Lopez-Diaz de Cerio, A.; Ponz-Sarvise, M.; Resano, L.; Berraondo, P.; Barbes, B.; Martin-Algarra, S.; Gurpide, A.; Sanmamed, M.
ANNALS OF ONCOLOGY
0923-7534 (2018)
DOI /
10.1093/annonc/mdy089
Hybrid
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4
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0
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An Integrative Approach to Inform Optimal Administration of OX40 Agonist Antibodies in Patients with Advanced Solid Tumors
Wang, Rui; Gao, Chan; Raymond, Megan; Dito, Gennaro; Kabbabe, Dominic; Shao, Xiao; Hilt, Ed; Sun, Yongliang; Pak, Irene; Gutierrez, Martin; Melero, Ignacio; Spreafico, Anna; Carvajal, Richard D.; Ong, Michael; Olszanski, Anthony J.; Milburn, Christina; Thu
CLINICAL CANCER RESEARCH
1078-0432 (2019)
DOI /
10.1158/1078-0432.ccr-19-0526
Bronze
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10
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0
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0
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0
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Epitope spreading driven by the joint action of CART cells and pharmacological STING stimulation counteracts tumor escape via antigen-loss variants
Conde, Enrique; Vercher, Enric; Soria-Castellano, Marta; Suarez-Olmos, Jesus; Mancheno, Uxua; Elizalde, Edurne; Luis Rodriguez, M.; Glez-Vaz, Javier; Casares, Noelia; Rodriguez-Garcia, Estefania; Hommel, Mirja; Gonzalez-Aseguinolaza, Gloria; Uranga-Murillo
JOURNAL FOR IMMUNOTHERAPY OF CANCER
(2021)
DOI /
10.1136/jitc-2021-003351
Gold
Mentions
9
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0
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0
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0
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Review
Immunotherapy of Hepatocellular Carcinoma: Facts and Hopes
Inarrairaegui, Mercedes; Melero, Ignacio; Sangro, Bruno
CLINICAL CANCER RESEARCH
1078-0432 (2018)
DOI /
10.1158/1078-0432.ccr-17-0289
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12
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0
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0
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0
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Repurposing infectious disease vaccines for intratumoral immunotherapy
Melero, Ignacio; Gato, Maria; Shekarian, Tala; Aznar, Angela; Valsesia-Wittmann, Sandrine; Caux, Christophe; Etxeberrria, Inaki; Teijeira, Alvaro; Marabelle, Aurelien
JOURNAL FOR IMMUNOTHERAPY OF CANCER
(2020)
DOI /
10.1136/jitc-2019-000443
Green published, Gold
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4
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0
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0
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0
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Article
Diverse immune environments in human lung tuberculosis granulomas assessed by quantitative multiplexed immunofluorescence
Abengozar-Muela, Marta; Esparza, Maria Villalba; Garcia-Ros, David; Vasquez, Cindy Estefania; Echeveste, Jose I.; Idoate, Miguel Angel; Lozano, Maria D.; Melero, Ignacio; de Andrea, Carlos E.
MODERN PATHOLOGY
0893-3952 (2020)
DOI /
10.1038/s41379-020-0600-6
Mentions
8
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0
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0
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0
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Introducing a New Series: Immunotherapy Facts and Hopes
Melero, Ignacio; Sznol, Mario; Tessmer, Marlowe S.; Whiteside, Theresa L.; Wolchok, Jedd D.
CLINICAL CANCER RESEARCH
1078-0432 (2018)
DOI /
10.1158/1078-0432.ccr-18-0408
Bronze
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7
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0
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0
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0
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Review
Strategies to design clinical studies to identify predictive biomarkers in cancer research
Perez-Gracia, Jose Luis; Sanmamed, Miguel F.; Bosch, Ana; Patino-Garcia, Ana; Schalper, Kurt A.; Segura, Victor; Bellmunt, Joaquim; Tabernero, Josep; Sweeney, Christopher J.; Choueiri, Toni K.; Martin, Miguel; Pablo Fusco, Juan; Esperanza Rodriguez-Ruiz, M
CANCER TREATMENT REVIEWS
0305-7372 (2017)
DOI /
10.1016/j.ctrv.2016.12.005
Gold other, Green published
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4
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0
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0
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0
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Article
Radiation effects on antitumor immune responses: current perspectives and challenges
Walle, Thomas; Martinez Monge, Rafael; Cerwenka, Adelheid; Ajona, Daniel; Melero, Ignacio; Lecanda, Fernando
THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY
1758-8340 (2018)
DOI /
10.1177/1758834017742575
Gold, Green published
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5
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0
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Article
Short-Term Local Expression of a PD-L1 Blocking Antibody from a Self-Replicating RNA Vector Induces Potent Antitumor Responses
Cristina Ballesteros-Briones, Maria; Martisova, Eva; Casales, Erkuden; Silva-Pilipich, Noelia; Bunuales, Maria; Galindo, Javier; Mancheno, Uxua; Gorraiz, Marta; Lasarte, Juan J.; Kochan, Grazyna; Escors, David; Sanchez-Paulete, Alfonso R.; Melero, Ignacio;
MOLECULAR THERAPY
1525-0016 (2019)
DOI /
10.1016/j.ymthe.2019.09.016
Green published, Hybrid
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6
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0
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0
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0
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Article
Genomic characterization of individuals presenting extreme phenotypes of high and low risk to develop tobacco-induced lung cancer
Pablo Fusco, Juan; Pita, Guillermo; Jose Pajares, Maria; Pilar Andueza, Maria; Patino-Garcia, Ana; de-Torres, Juan P.; Gurpide, Alfonso; Zulueta, Javier; Alonso, Rosario; Alvarez, Nuria; Rio, Ruben; Melero, Ignacio I.; Sanmamed, Miguel F; Rodriguez Ruiz, M
CANCER MEDICINE
2045-7634 (2018)
DOI /
10.1002/cam4.1500
Gold DOAJ, Green published
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5
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0
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0
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0
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Article
Mitochondria! Morphological and Functional Reprogramming Following CD137 (4-1BB) Costimulation
Teijeira, Alvaro; Labiano, Sara; Garasa, Saray; Etxeberria, Inaki; Santamaria, Eva; Rouzaut, Ana; Enamorado, Michel; Azpilikueta, Arantza; Inoges, Susana; Bolanos, Elixabet; Angela Aznar, Maria; Sanchez-Paulete, Alfonso R.; Sancho, David; Melero, Ignacio
CANCER IMMUNOLOGY RESEARCH
2326-6066 (2018)
DOI /
10.1158/2326-6066.cir-17-0767
Bronze
Mentions
7
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0
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0
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0
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Review
IL8, Neutrophils, and NETs in a Collusion against Cancer Immunity and Immunotherapy
Teijeira, Alvaro; Garasa, Saray; Ochoa, Maria C.; Villalba, Maria; Olivera, Irene; Cirella, Assunta; Eguren-Santamaria, Inaki; Berraondo, Pedro; Schalper, Kurt A.; de Andrea, Carlos E.; Sanmamed, Miguel F.; Melero, Ignacio
CLINICAL CANCER RESEARCH
1078-0432 (2021)
DOI /
10.1158/1078-0432.ccr-20-1319
Mentions
2
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0
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0
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0
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Editorial Material
Firefighters for the Wrong Type of Inflammation in Tumors
Melero, Ignacio; Teijeira, Alvaro; Aranda, Fernando; Berraondo, Pedro
CANCER DISCOVERY
2159-8274 (2021)
DOI /
10.1158/2159-8290.cd-21-1004
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4
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0
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0
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0
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Article
Quantitative and qualitative impairments in dendritic cell subsets of patients with ovarian or prostate cancer
Mastelic-Gavillet, Beatris; Sarivalasis, Apostolos; Lozano, Leyder Elena; Wyss, Tania; Inoges, Susana; de Vries, Ingrid Jolanda Monique; Dartiguenave, Florence; Jichlinski, Patrice; Derre, Laurent; Coukos, George; Melero, Ignacio; Harari, Alexandre; Romero
EUROPEAN JOURNAL OF CANCER
0959-8049 (2020)
DOI /
10.1016/j.ejca.2020.04.036
Gold other
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4
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0
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0
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0
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Editorial Material
Consolidating Radiotherapy with Immunotherapy
Rodriguez-Ruiz, Maria E.; Sanmamed, Miguel F.; Serrano-Mendioroz, Irantzu; Melero, Ignacio
CLINICAL CANCER RESEARCH
1078-0432 (2021)
DOI /
10.1158/1078-0432.ccr-21-2335
Mentions
4
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0
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0
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0
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Editorial Material
Twists and turns to translating 4-1BB cancer immunotherapy
Sanmamed, Miguel F.; Etxeberria, Inaki; Otano, Itziar; Melero, Ignacio
SCIENCE TRANSLATIONAL MEDICINE
1946-6234 (2019)
DOI /
10.1126/scitranslmed.aax4738
Mentions
6
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0
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0
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Article
Cellular cytotoxicity is a form of immunogenic cell death
Minute, Luna; Teijeira, Alvaro; Sanchez-Paulete, Alfonso R.; Ochoa, Maria C.; Alvarez, Maite; Otano, Itziar; Etxeberrria, Inaki; Bolanos, Elixabet; Azpilikueta, Arantza; Garasa, Saray; Casares, Noelia; Perez Gracia, Jose Luis; Rodriguez-Ruiz, Maria E.; Ber
JOURNAL FOR IMMUNOTHERAPY OF CANCER
(2020)
DOI /
10.1136/jitc-2019-000325
Green published, Gold
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1
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0
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0
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0
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International Symposium: Trailblazing in Cancer Immunotherapy, October 29-31, 2017, Pamplona, Spain
Berraondo, Pedro; Angela Aznar, Maria; Perez-Ruiz, Elisabeth; Esperanza Rodriguez-Ruiz, Maria; Castanon, Eduardo; Luis Perez-Gracia, Jose; Melero, Ignacio
CANCER IMMUNOLOGY IMMUNOTHERAPY
0340-7004 (2018)
DOI /
10.1007/s00262-018-2240-y
Mentions
2
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0
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Article
Daratumumab in combination with urelumab to potentiate anti-myeloma activity in lymphocyte-deficient mice reconstituted with human NK cells
Ochoa, Maria C.; Perez-Ruiz, Elisabeth; Minute, Luna; Onate, Carmen; Perez, Guiomar; Rodriguez, Inmaculada; Zabaleta, Aintzane; Alignani, Diego; Fernandez-Sendin, Myriam; Lopez, Ascension; Muntasell, Aura; Sanmamed, Miguel F.; Paiva, Bruno; Lopez-Botet, Mi
ONCOIMMUNOLOGY
2162-4011 (2019)
DOI /
10.1080/2162402x.2019.1599636
Gold other, Green published
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2
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0
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0
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0
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Immunodivergence in Metastatic Colorectal Cancer
de Andrea, Carlos E.; Schalper, Kurt A.; Sanmamed, Miguel F.; Melero, Ignacio
CANCER CELL
1535-6108 (2018)
DOI /
10.1016/j.ccell.2018.11.012
Bronze, Green accepted
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2
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0
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0
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Article
CD69 is a direct HIF-1 alpha target gene in hypoxia as a mechanism enhancing expression on tumor-infiltrating T lymphocytes
Labiano, Sara; Melendez-Rodriguez, Florinda; Palazon, Asis; Teijeira, Alvaro; Garasa, Saray; Etxeberria, Inaki; Angela Aznar, M.; Sanchez-Paulete, Alfonso R.; Azpilikueta, Arantza; Bolanos, Elixabet; Molina, Carmen; de la Fuente, Hortensia; Maiso, Patricia
ONCOIMMUNOLOGY
2162-4011 (2017)
DOI /
10.1080/2162402x.2017.1283468
Green published, Gold
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2
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0
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Article
Enhancement of antibody-dependent cellular cytotoxicity of cetuximab by a chimeric protein encompassing interleukin-15
Carmen Ochoa, Maria; Minute, Luna; Lopez, Ascension; Perez-Ruiz, Elisabeth; Gomar, Celia; Vasquez, Marcos; Inoges, Susana; Etxeberria, Inaki; Rodriguez, Inmaculada; Garasa, Saray; Mayer, Jan-Peter Andreas; Wirtz, Peter; Melero, Ignacio; Berraondo, Pedro
ONCOIMMUNOLOGY
2162-4011 (2018)
DOI /
10.1080/2162402x.2017.1393597
Green published, Gold other
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1
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0
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0
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Review
Rapid isolation and enrichment of mouse NK cells for experimental purposes
Alvarez, Maite; Ochoa, Maria C.; Minute, Luna; Melero, Ignacio; Berraondo, Pedro
TUMOR IMMUNOLOGY AND IMMUNOTHERAPY - CELLULAR METHODS, PT A
0076-6879 (2020)
DOI /
10.1016/bs.mie.2019.10.025
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1
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0
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0
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Cellular immunotherapies for cancer
Berraondo, Pedro; Labiano, Sara; Minute, Luna; Etxeberria, Inaki; Vasquez, Marcos; Sanchez-Arraez, Alvaro; Teijeira, Alvaro; Melero, Ignacio
ONCOIMMUNOLOGY
2162-4011 (2017)
DOI /
10.1080/2162402x.2017.1306619
Green published, Bronze
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2
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0
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0
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0
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Article
Deubiquitinases A20 and CYLD modulate costimulatory signaling via CD137 (4-1BB)
Azpilikueta, Arantza; Bolanos, Elixabet; Lang, Valerie; Labiano, Sara; Aznar, Maria A.; Etxeberria, Inaki; Teijeira, Alvaro; Rodriguez-Ruiz, Maria E.; Perez-Gracia, Jose L.; Jure-Kunkel, Maria; Zapata, Juan M.; Rodriguez, Manuel S.; Melero, Ignacio
ONCOIMMUNOLOGY
2162-4011 (2018)
DOI /
10.1080/2162402x.2017.1368605
Green submitted, Gold, Green published
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4
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0
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0
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0
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Article
Metabolic Consequences of T-cell Costimulation in Anticancer Immunity
Teijeira, Alvaro; Garasa, Saray; Etxeberria, Inaki; Gato-Canas, Maria; Melero, Ignacio; Delgoffe, Greg M.
CANCER IMMUNOLOGY RESEARCH
2326-6066 (2019)
DOI /
10.1158/2326-6066.cir-19-0115
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4
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0
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Review
New emerging targets in cancer immunotherapy: CD137/4-1BB costimulatory axis
Etxeberria, Inaki; Glez-Vaz, Javier; Teijeira, Alvaro; Melero, Ignacio
ESMO OPEN
(2019)
DOI /
10.1136/esmoopen-2020-000733
Gold DOAJ, Green published
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1
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0
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0
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0
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Editorial Material
Revisiting anti-CTLA-4 antibodies in combination with PD-1 blockade for cancer immunotherapy
Sznol, M.; Melero, I.
ANNALS OF ONCOLOGY
0923-7534 (2021)
DOI /
10.1016/j.annonc.2020.11.018
Mentions
1
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0
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0
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0
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Article
Intercellular Adhesion Molecule-1 and Vascular Cell Adhesion Molecule Are Induced by Ionizing Radiation on Lymphatic Endothelium
Rodriguez-Ruiz, Maria E.; Garasa, Saray; Rodriguez, Inmaculada; Luis Solorzano, Jose; Barbes, Benigno; Yanguas, Alba; Teijeira, Alvaro; Etxeberria, Inaki; Javier Aristu, Jose; Halin, Cornelia; Melero, Ignacio; Rouzaut, Ana
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
0360-3016 (2017)
DOI /
10.1016/j.ijrobp.2016.10.043
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1
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0
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0
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Editorial Material
Neoadjuvant immunotherapy in non-small cell lung cancer: the sooner the better?
Luis Perez-Gracia, Jose; Sanmamed, Miguel F.; Melero, Ignacio
TRANSLATIONAL LUNG CANCER RESEARCH
2218-6751 (2018)
DOI /
10.21037/tlcr.2018.10.12
Green published
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1
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0
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0
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0
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Editorial Material
Exploiting TCR Recognition of Shared Hotspot Oncogene-encoded Neoantigens
Olivera, Irene; Etxeberria, Inaki; Bolanos, Elixabet; Gato-Canas, Maria; Melero, Ignacio
CLINICAL CANCER RESEARCH
1078-0432 (2020)
DOI /
10.1158/1078-0432.ccr-19-3813
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2
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0
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0
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0
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Editorial Material
Interleukin-12 Message in a Bottle
Cirella, Assunta; Berraondo, Pedro; Di Trani, Claudia Augusta; Melero, Ignacio
CLINICAL CANCER RESEARCH
1078-0432 (2020)
DOI /
10.1158/1078-0432.ccr-20-3250
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2
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0
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0
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Vaccination for Pancreatic Ductal Adenocarcinoma: A Hard Nut to Crack
Salas-Benito, Diego; Melero, Ignacio; Ponz-Sarvise, Mariano
CLINICAL CANCER RESEARCH
1078-0432 (2019)
DOI /
10.1158/1078-0432.ccr-19-1753
Bronze
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5
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0
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Article
Statins act as transient type I interferon inhibitors to enable the antitumor activity of modified vaccinia Ankara viral vectors
Tenesaca, Shirley; Vasquez, Marcos; Alvarez, Maite; Otano, Itziar; Fernandez-Sendin, Myriam; Augusta Di Trani, Claudia; Ardaiz, Nuria; Gomar, Celia; Bella, Angela; Aranda, Fernando; Medina-Echeverz, Jose; Melero, Ignacio; Berraondo, Pedro
JOURNAL FOR IMMUNOTHERAPY OF CANCER
(2021)
DOI /
10.1136/jitc-2020-001587
Gold, Green published
