Immunology

Listando 39 trabajos del autor/autora 38

Lista de trabajos en el área Immunology

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Article CD137 (4-1BB) costimulation of CD8(+) T cells is more potent when provided in cis than in trans with respect to CD3-TCR stimulation Otano, Itziar; Azpilikueta, Arantza; Glez-Vaz, Javier; Alvarez, Maite; Medina-Echeverz, Jose; Cortes-Dominguez, Ivan; Ortiz-de-Solorzano, Carlos; Ellmark, Peter; Fritzell, Sara; Hernandez-Hoyos, Gabriela; Hase Nelson, Michelle; Carmen Ochoa, Maria; Bolanos NATURE COMMUNICATIONS (2021) DOI / 10.1038/s41467-021-27613-w

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Review Growth/Differentiation Factor-15 (GDF-15): From Biomarker to Novel Targetable Immune Checkpoint Wischhusen, Joerg; Melero, Ignacio; Fridman, Wolf Herman FRONTIERS IN IMMUNOLOGY 1664-3224 (2020) DOI / 10.3389/fimmu.2020.00951 Gold other, Green published

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Article Intratumoral co-injection of the poly I:C-derivative BO-112 and a STING agonist synergize to achieve local and distant anti-tumor efficacy Alvarez, Maite; Molina, Carmen; de Andrea, Carlos E.; Fernandez-Sendin, Myriam; Villalba, Maria; Gonzalez-Gomariz, Jose; Carmen Ochoa, Maria; Teijeira, Alvaro; Glez-Vaz, Javier; Aranda, Fernando; Sanmamed, Miguel F.; Rodriguez-Ruiz, Maria E.; Fan, Xinyi; S JOURNAL FOR IMMUNOTHERAPY OF CANCER (2021) DOI / 10.1136/jitc-2021-002953 Gold, Green published

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Review Dendritic cells in cancer immunology and immunotherapy Wculek, Stefanie K.; Cueto, Francisco J.; Mujal, Adriana M.; Melero, Ignacio; Krummel, Matthew F.; Sancho, David NATURE REVIEWS IMMUNOLOGY 1474-1733 (2020) DOI / 10.1038/s41577-019-0210-z

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Article Enhanced anti-tumour immunity requires the interplay between resident and circulating memory CD8(+) T cells Enamorado, Michel; Iborra, Salvador; Priego, Elena; Cueto, Francisco J.; Quintana, Juan A.; Martinez-Cano, Sarai; Mejias-Perez, Ernesto; Esteban, Mariano; Melero, Ignacio; Hidalgo, Andres; Sancho, David NATURE COMMUNICATIONS (2017) DOI / 10.1038/ncomms16073 Gold DOAJ, Green published

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Article DNGR-1 limits Flt3L-mediated antitumor immunity by restraining tumor-infiltrating type I conventional dendritic cells Cueto, Francisco J.; del Fresno, Carlos; Brandi, Paola; Combes, Alexis J.; Hernandez-Garcia, Elena; Sanchez-Paulete, Alfonso R.; Enamorado, Michel; Bromley, Christian P.; Gomez, Manuel J.; Conde-Garrosa, Ruth; Manes, Santos; Zelenay, Santiago; Melero, Igna JOURNAL FOR IMMUNOTHERAPY OF CANCER (2021) DOI / 10.1136/jitc-2020-002054

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Article CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity Teijeira, Alvaro; Garasa, Saray; Gato, Maria; Alfaro, Carlos; Migueliz, Itziar; Cirella, Assunta; de Andrea, Carlos; Carmen Ochoa, Maria; Otano, Itziar; Etxeberria, Inaki; Pilar Andueza, Maria; Nieto, Celia P.; Resano, Leyre; Azpilikueta, Arantza; Allegret IMMUNITY 1074-7613 (2020) DOI / 10.1016/j.immuni.2020.03.001 Bronze

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Review Immunological Mechanisms Responsible for Radiation-Induced Abscopal Effect Rodriguez-Ruiz, Maria E.; Vanpouille-Box, Claire; Melero, Ignacio; Formenti, Silvia Chiara; Demaria, Sandra TRENDS IN IMMUNOLOGY 1471-4906 (2018) DOI / 10.1016/j.it.2018.06.001 Green accepted

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Article Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of hepatocellular carcinoma Greten, Tim F.; Abou-Alfa, Ghassan K.; Cheng, Ann-Lii; Duffy, Austin G.; El-Khoueiry, Anthony B.; Finn, Richard S.; Galle, Peter R.; Goyal, Lipika; He, Aiwu Ruth; Kaseb, Ahmed O.; Kelley, Robin Kate; Lencioni, Riccardo; Lujambio, Amaia; Mabry Hrones, Donna JOURNAL FOR IMMUNOTHERAPY OF CANCER (2021) DOI / 10.1136/jitc-2021-002794 Green published, Gold

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Review Immunological impact of cell death signaling driven by radiation on the tumor microenvironment Esperanza Rodriguez-Ruiz, Maria; Vitale, Ilio; Harrington, Kevin J.; Melero, Ignacio; Galluzzi, Lorenzo NATURE IMMUNOLOGY 1529-2908 (2019) DOI / 10.1038/s41590-019-0561-4

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Review Intratumoral Delivery of Immunotherapy-Act Locally, Think Globally Angela Aznar, M.; Tinari, Nicola; Rullan, Antonio J.; Sanchez-Paulete, Alfonso R.; Rodriguez-Ruiz, Maria E.; Melero, Ignacio JOURNAL OF IMMUNOLOGY 0022-1767 (2017) DOI / 10.4049/jimmunol.1601145 Bronze

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Review Antibody-dependent cell cytotoxicity: immunotherapy strategies enhancing effector NK cells Carmen Ochoa, Maria; Minute, Luna; Rodriguez, Inmaculada; Garasa, Saray; Perez-Ruiz, Elisabeth; Inoges, Susana; Melero, Ignacio; Berraondo, Pedro IMMUNOLOGY AND CELL BIOLOGY 0818-9641 (2017) DOI / 10.1038/icb.2017.6

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Review The clinical application of cancer immunotherapy based on naturally circulating dendritic cells Bol, Kalijn F.; Schreibelt, Gerty; Rabold, Katrin; Wculek, Stefanie K.; Schwarze, Julia Katharina; Dzionek, Andrzej; Teijeira, Alvaro; Kandalaft, Lana E.; Romero, Pedro; Coukos, George; Neyns, Bart; Sancho, David; Melero, Ignacio; de Vries, I. Jolanda M. JOURNAL FOR IMMUNOTHERAPY OF CANCER (2019) DOI / 10.1186/s40425-019-0580-6 Gold DOAJ, Green published

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Review Perspectives in immunotherapy: meeting report from the Immunotherapy Bridge (29-30 November, 2017, Naples, Italy) Ascierto, Paolo A.; Brugarolas, James; Buonaguro, Luigi; Butterfield, Lisa H.; Carbone, David; Daniele, Bruno; Ferris, Robert; Fox, Bernard A.; Galon, Jerome; Gridelli, Cesare; Kaufman, Howard L.; Klebanoff, Christopher A.; Melero, Ignacio; Nathan, Paul; P JOURNAL FOR IMMUNOTHERAPY OF CANCER (2018) DOI / 10.1186/s40425-018-0377-z Gold DOAJ, Green published

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Article A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicity Compte, Marta; Lykke Harwood, Seandean; Munoz, Ines G.; Navarro, Rocio; Zonca, Manuela; Perez-Chacon, Gema; Erce-Llamazares, Ainhoa; Merino, Nekane; Tapia-Galisteo, Antonio; Cuesta, Angel M.; Mikkelsen, Kasper; Caleiras, Eduardo; Nunez-Prado, Natalia; Azna NATURE COMMUNICATIONS (2018) DOI / 10.1038/s41467-018-07195-w Green published, Gold

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Article Immunotherapeutic effects of intratumoral nanoplexed poly I:C Angela Aznar, M.; Planelles, Lourdes; Perez-Olivares, Mercedes; Molina, Carmen; Garasa, Saray; Etxeberria, Inaki; Perez, Guiomar; Rodriguez, Inmaculada; Bolanos, Elixabet; Lopez-Casas, Pedro; Rodriguez-Ruiz, Maria E.; Perez-Gracia, Jose L.; Marquez-Rodas, JOURNAL FOR IMMUNOTHERAPY OF CANCER (2019) DOI / 10.1186/s40425-019-0568-2 Green published, Gold

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Article CD137 (4-1BB) Costimulation Modifies DNA Methylation in CD8(+) T Cell-Relevant Genes Angela Aznar, M.; Labiano, Sara; Diaz-Lagares, Angel; Molina, Carmen; Garasa, Saray; Azpilikueta, Arantza; Etxeberria, Inaki; Sanchez-Paulete, Alfonso R.; Korman, Alan J.; Esteller, Manel; Sandoval, Juan; Melero, Ignacio CANCER IMMUNOLOGY RESEARCH 2326-6066 (2018) DOI / 10.1158/2326-6066.cir-17-0159

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Article Effective cancer immunotherapy by natural mouse conventional type-1 dendritic cells bearing dead tumor antigen Wculek, Stefanie K.; Amores-Iniesta, Joaquin; Conde-Garrosa, Ruth; Khouili, Sofia C.; Melero, Ignacio; Sancho, David JOURNAL FOR IMMUNOTHERAPY OF CANCER (2019) DOI / 10.1186/s40425-019-0565-5 Green published, Gold

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Article A randomized phase II clinical trial of dendritic cell vaccination following complete resection of colon cancer liver metastasis Rodriguez, Javier; Castanon, Eduardo; Luis Perez-Gracia, Jose; Rodriguez, Inmaculada; Viudez, Antonio; Alfaro, Carlos; Onate, Carmen; Perez, Guiomar; Rotellar, Fernando; Inoges, Susana; Lopez-Diaz de Cerio, Ascension; Resano, Leyre; Ponz-Sarvise, Mariano; JOURNAL FOR IMMUNOTHERAPY OF CANCER (2018) DOI / 10.1186/s40425-018-0405-z Gold DOAJ, Green published

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Article Intratumoral virotherapy with 4-1BBL armed modified vaccinia Ankara eradicates solid tumors and promotes protective immune memory Hinterberger, Maria; Giessel, Raphael; Fiore, Giovanna; Graebnitz, Fabienne; Bathke, Barbara; Wennier, Sonia; Chaplin, Paul; Melero, Ignacio; Suter, Mark; Lauterbach, Henning; Berraondo, Pedro; Hochrein, Hubertus; Medina-Echeverz, Jose JOURNAL FOR IMMUNOTHERAPY OF CANCER (2021) DOI / 10.1136/jitc-2020-001586 Gold DOAJ, Green published

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Editorial Material 4-1BB (CD137) in anticancer chimeras Melero, Ignacio; Berraondo, Pedro JOURNAL OF EXPERIMENTAL MEDICINE 0022-1007 (2020) DOI / 10.1084/jem.20201562 Bronze

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Article CD137 Costimulation Counteracts TGF beta Inhibition of NK-cell Antitumor Function Cabo, Mariona; Santana-Hernandez, Sara; Costa-Garcia, Marcel; Rea, Anna; Lozano-Rodriguez, Roberto; Ataya, Michelle; Balaguer, Francesc; Juan, Manel; Ochoa, Maria C.; Menendez, Silvia; Comerma, Laura; Rovira, Ana; Berraondo, Pedro; Albanell, Joan; Melero, CANCER IMMUNOLOGY RESEARCH 2326-6066 (2021) DOI / 10.1158/2326-6066.cir-21-0030

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Article Epitope spreading driven by the joint action of CART cells and pharmacological STING stimulation counteracts tumor escape via antigen-loss variants Conde, Enrique; Vercher, Enric; Soria-Castellano, Marta; Suarez-Olmos, Jesus; Mancheno, Uxua; Elizalde, Edurne; Luis Rodriguez, M.; Glez-Vaz, Javier; Casares, Noelia; Rodriguez-Garcia, Estefania; Hommel, Mirja; Gonzalez-Aseguinolaza, Gloria; Uranga-Murillo JOURNAL FOR IMMUNOTHERAPY OF CANCER (2021) DOI / 10.1136/jitc-2021-003351 Gold

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Review Targeting NK-cell checkpoints for cancer immunotherapy Muntasell, Aura; Ochoa, Maria C.; Cordeiro, Luna; Berraondo, Pedro; Lopez-Diaz de Cerio, Ascension; Cabo, Mariona; Lopez-Botet, Miguel; Melero, Ignacio CURRENT OPINION IN IMMUNOLOGY 0952-7915 (2017) DOI / 10.1016/j.coi.2017.01.003

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Editorial Material Repurposing infectious disease vaccines for intratumoral immunotherapy Melero, Ignacio; Gato, Maria; Shekarian, Tala; Aznar, Angela; Valsesia-Wittmann, Sandrine; Caux, Christophe; Etxeberrria, Inaki; Teijeira, Alvaro; Marabelle, Aurelien JOURNAL FOR IMMUNOTHERAPY OF CANCER (2020) DOI / 10.1136/jitc-2019-000443 Green published, Gold

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Review CD137 (4-1BB) Signalosome: Complexity Is a Matter of TRAFs Zapata, Juan M.; Perez-Chacon, Gema; Carr-Baena, Pablo; Martinez-Forero, Ivan; Azpilikueta, Arantza; Otano, Itziar; Melero, Ignacio FRONTIERS IN IMMUNOLOGY 1664-3224 (2018) DOI / 10.3389/fimmu.2018.02618 Gold DOAJ, Green published

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Article Mitochondria! Morphological and Functional Reprogramming Following CD137 (4-1BB) Costimulation Teijeira, Alvaro; Labiano, Sara; Garasa, Saray; Etxeberria, Inaki; Santamaria, Eva; Rouzaut, Ana; Enamorado, Michel; Azpilikueta, Arantza; Inoges, Susana; Bolanos, Elixabet; Angela Aznar, Maria; Sanchez-Paulete, Alfonso R.; Sancho, David; Melero, Ignacio CANCER IMMUNOLOGY RESEARCH 2326-6066 (2018) DOI / 10.1158/2326-6066.cir-17-0767 Bronze

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Article Cellular cytotoxicity is a form of immunogenic cell death Minute, Luna; Teijeira, Alvaro; Sanchez-Paulete, Alfonso R.; Ochoa, Maria C.; Alvarez, Maite; Otano, Itziar; Etxeberrria, Inaki; Bolanos, Elixabet; Azpilikueta, Arantza; Garasa, Saray; Casares, Noelia; Perez Gracia, Jose Luis; Rodriguez-Ruiz, Maria E.; Ber JOURNAL FOR IMMUNOTHERAPY OF CANCER (2020) DOI / 10.1136/jitc-2019-000325 Green published, Gold

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Editorial Material International Symposium: Trailblazing in Cancer Immunotherapy, October 29-31, 2017, Pamplona, Spain Berraondo, Pedro; Angela Aznar, Maria; Perez-Ruiz, Elisabeth; Esperanza Rodriguez-Ruiz, Maria; Castanon, Eduardo; Luis Perez-Gracia, Jose; Melero, Ignacio CANCER IMMUNOLOGY IMMUNOTHERAPY 0340-7004 (2018) DOI / 10.1007/s00262-018-2240-y