Clinical Medicine


  Listando 110 trabajos del autor/autora 39
Lista de trabajos en el área Clinical Medicine
Mentions   1   Wikipedia   194   News   2   Policy
Article Durvalumab after Chemoradiotherapy in Stage III Non-Small-Cell Lung Cancer Antonia, S. J.; Villegas, A.; Daniel, D.; Vicente, D.; Murakami, S.; Hui, R.; Yokoi, T.; Chiappori, A.; Lee, K. H.; de Wit, M.; Cho, B. C.; Bourhaba, M.; Quantin, X.; Tokito, T.; Mekhail, T.; Planchard, D.; Kim, Y. -C.; Karapetis, C. S.; Hiret, S.; Ostoros NEW ENGLAND JOURNAL OF MEDICINE 0028-4793 (2017) DOI / 10.1056/nejmoa1709937 Green published
Mentions   2   Wikipedia   44   News   1   Policy
Article Nivolumab plus Ipilimumab in Lung Cancer with a High Tumor Mutational Burden Hellmann, M. D.; Ciuleanu, T. -E.; Pluzanski, A.; Lee, J. S.; Otterson, G. A.; Audigier-Valette, C.; Minenza, E.; Linardou, H.; Burgers, S.; Salman, P.; Borghaei, H.; Ramalingam, S. S.; Brahmer, J.; Reck, M.; O'Byrne, K. J.; Geese, W. J.; Green, G.; Chang, NEW ENGLAND JOURNAL OF MEDICINE 0028-4793 (2018) DOI / 10.1056/nejmoa1801946 Green accepted, Bronze
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Article Trastuzumab Deruxtecan in HER2-Mutant Non-Small-Cell Lung Cancer Li, Bob T.; Smit, Egbert F.; Goto, Yasushi; Nakagawa, Kazuhiko; Udagawa, Hibiki; Mazieres, Julien; Nagasaka, Misako; Bazhenova, Lyudmila; Saltos, Andreas N.; Felip, Enriqueta; Pacheco, Jose M.; Perol, Maurice; Paz-Ares, Luis; Saxena, Kapil; Shiga, Ryota; C NEW ENGLAND JOURNAL OF MEDICINE 0028-4793 (2021) DOI / 10.1056/nejmoa2112431
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Article First-Line Nivolumab in Stage IV or Recurrent Non-Small-Cell Lung Cancer Carbone, D. P.; Reck, M.; Paz-Ares, L.; Creelan, B.; Horn, L.; Steins, M.; Felip, E.; Van Den Heuvel, M. M.; Ciuleanu, T. -E.; Badin, F.; Ready, N.; Hiltermann, T. J. N.; Nair, S.; Juergens, R.; Peters, S.; Minenza, E.; Wrangle, J. M.; Rodriguez-Abreu, D.; NEW ENGLAND JOURNAL OF MEDICINE 0028-4793 (2017) DOI / 10.1056/nejmoa1613493 Green published, Green accepted, Bronze
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Review Current and Emergent Therapy Options for Advanced Squamous Cell Lung Cancer Socinski, Mark A.; Obasaju, Coleman; Gandara, David; Hirsch, Fred R.; Bonomi, Philip; Bunn, Paul A., Jr.; Kim, Edward S.; Langer, Corey J.; Natale, Ronald B.; Novello, Silvia; Paz-Ares, Luis; Perol, Maurice; Reck, Martin; Ramalingam, Suresh S.; Reynolds, C JOURNAL OF THORACIC ONCOLOGY 1556-0864 (2018) DOI / 10.1016/j.jtho.2017.11.111 Bronze
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Article EGFR Gene Copy Number by FISH May Predict Outcome of Necitumumab in Squamous Lung Carcinomas: Analysis from the SQUIRE Study Genova, Carlo; Socinski, Mark A.; Hozak, Rebecca R.; Mi, Gu; Kurek, Raffael; Shahidi, Javad; Paz-Ares, Luis; Thatcher, Nick; Rivard, Christopher J.; Varella-Garcia, Marileila; Hirsch, Fred R. JOURNAL OF THORACIC ONCOLOGY 1556-0864 (2018) DOI / 10.1016/j.jtho.2017.11.109 Bronze, Green accepted
Mentions   0   Wikipedia   52   News   2   Policy
Article Durvalumab plus platinum-etoposide versus platinum-etoposide in first-line treatment of extensive-stage small-cell lung cancer (CASPIAN): a randomised, controlled, open-label, phase 3 trial Paz-Ares, Luis; Dvorkin, Mikhail; Chen, Yuanbin; Reinmuth, Niels; Hotta, Katsuyuki; Trukhin, Dmytro; Statsenko, Galina; Hochmair, Maximilian J.; Ozguroglu, Mustafa; Ji, Jun Ho; Voitko, Oleksandr; Poltoratskiy, Artem; Ponce, Santiago; Verderame, Francesco; LANCET 0140-6736 (2019) DOI / 10.1016/s0140-6736(19)32222-6
Mentions   1   Wikipedia   26   News   4   Policy
Article Pembrolizumab plus Chemotherapy for Squamous Non-Small-Cell Lung Cancer Paz-Ares, L.; Luft, A.; Vicente, D.; Tafreshi, A.; Gumus, M.; Mazieres, J.; Hermes, B.; Senler, F. Cay; Csoszi, T.; Fulop, A.; Rodriguez-Cid, J.; Wilson, J.; Sugawara, S.; Kato, T.; Lee, K. H.; Cheng, Y.; Novello, S.; Halmos, B.; Li, X.; Lubiniecki, G. M.; NEW ENGLAND JOURNAL OF MEDICINE 0028-4793 (2018) DOI / 10.1056/nejmoa1810865 Green published, Bronze
Mentions   2   Wikipedia   25   News   2   Policy
Article Nivolumab plus Ipilimumab in Advanced Non-Small-Cell Lung Cancer Hellmann, M. D.; Paz-Ares, L.; Bernabe Caro, R.; Zurawski, B.; Kim, S. -W.; Carcereny Costa, E.; Park, K.; Alexandru, A.; Lupinacci, L.; de la Mora Jimenez, E.; Sakai, H.; Albert, I.; Vergnenegre, A.; Peters, S.; Syrigos, K.; Barlesi, F.; Reck, M.; Borghae NEW ENGLAND JOURNAL OF MEDICINE 0028-4793 (2019) DOI / 10.1056/nejmoa1910231 Bronze
Mentions   3   Wikipedia   27   News   3   Policy
Article First-line ceritinib versus platinum-based chemotherapy in advanced ALK-rearranged non-small-cell lung cancer (ASCEND-4): a randomised, open-label, phase 3 study Soria, Jean-Charles; Tan, Daniel S. W.; Chiari, Rita; Wu, Yi-Long; Paz-Ares, Luis; Wolf, Juergen; Geater, Sarayut L.; Orlov, Sergey; Cortinovis, Diego; Yu, Chong-Jen; Hochmair, Maximillian; Cortot, Alexis B.; Tsai, Chun-Ming; Moro-Sibilot, Denis; Campelo, LANCET 0140-6736 (2017) DOI / 10.1016/s0140-6736(17)30123-x
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Article Pralsetinib for RET fusion-positive non-small-cell lung cancer (ARROW): a multi-cohort, open-label, phase 1/2 study Gainor, Justin F.; Curigliano, Giuseppe; Kim, Dong-Wan; Lee, Dae Ho; Besse, Benjamin; Baik, Christina S.; Doebele, Robert C.; Cassier, Philippe A.; Lopes, Gilberto; Tan, Daniel S. W.; Garralda, Elena; Paz-Ares, Luis G.; Cho, Byoung Chul; Gadgeel, Shirish M LANCET ONCOLOGY 1470-2045 (2021) DOI / 10.1016/s1470-2045(21)00247-3
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Article Ramucirumab plus erlotinib in patients with untreated, EGFR-mutated, advanced non-small-cell lung cancer (RELAY): a randomised, double-blind, placebo-controlled, phase 3 trial Nakagawa, Kazuhiko; Garon, Edward B.; Seto, Takashi; Nishio, Makoto; Aix, Santiago Ponce; Paz-Ares, Luis; Chiu, Chao-Hua; Park, Keunchil; Novello, Silvia; Nadal, Ernest; Imamura, Fumio; Yoh, Kiyotaka; Shih, Jin-Yuan; Au, Kwok Hung; Moro-Sibilot, Denis; Ena LANCET ONCOLOGY 1470-2045 (2019) DOI / 10.1016/s1470-2045(19)30634-5
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Article Afatinib versus gefitinib in patients with EGFR mutation-positive advanced non-small-cell lung cancer: overall survival data from the phase IIb LUX-Lung 7 trial Paz-Ares, L.; Tan, E. -H.; O'Byrne, K.; Zhang, L.; Hirsh, V.; Boyer, M.; Yang, J. C. -H.; Mok, T.; Lee, K. H.; Lu, S.; Shi, Y.; Lee, D. H.; Laskin, J.; Kim, D. -W.; Laurie, S. A.; Kolbeck, K.; Fan, J.; Dodd, N.; Marten, A.; Park, K. ANNALS OF ONCOLOGY 0923-7534 (2017) DOI / 10.1093/annonc/mdw611 Green published, Gold other
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Article First-line nivolumab plus ipilimumab combined with two cycles of chemotherapy in patients with non-small-cell lung cancer (CheckMate 9LA): an international, randomised, open-label, phase 3 trial Paz-Ares, Luis; Ciuleanu, Tudor-Eliade; Cobo, Manuel; Schenker, Michael; Zurawski, Bogdan; Menezes, Juliana; Richardet, Eduardo; Bennouna, Jaafar; Felip, Enriqueta; Juan-Vidal, Oscar; Alexandru, Aurelia; Sakai, Hiroshi; Lingua, Alejo; Salman, Pamela; Souqu LANCET ONCOLOGY 1470-2045 (2021) DOI / 10.1016/s1470-2045(20)30641-0
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Article Notch inhibition overcomes resistance to tyrosine kinase inhibitors in EGFR-driven lung adenocarcinoma Mur, Emilie Bousquet; Bernardo, Sara; Papon, Laura; Mancini, Maicol; Fabbrizio, Eric; Goussard, Marion; Ferrer, Irene; Giry, Anais; Quantin, Xavier; Pujol, Jean-Louis; Calvayrac, Olivier; Moll, Herwig P.; Glasson, Yael; Pirot, Nelly; Turtoi, Andrei; Caname JOURNAL OF CLINICAL INVESTIGATION 0021-9738 (2020) DOI / 10.1172/jci126896 Bronze, Green published
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Article First-Line Nivolumab Plus Ipilimumab in Advanced Non-Small-Cell Lung Cancer (CheckMate 568): Outcomes by Programmed Death Ligand 1 and Tumor Mutational Burden as Biomarkers Ready, Neal; Hellmann, Matthew D.; Awad, Mark M.; Otterson, Gregory A.; Gutierrez, Martin; Gainor, Justin F.; Borghaei, Hossein; Jolivet, Jacques; Horn, Leora; Mates, Mihaela; Brahmer, Julie; Rabinowitz, Ian; Reddy, Pavan S.; Chesney, Jason; Orcutt, James; JOURNAL OF CLINICAL ONCOLOGY 0732-183X (2019) DOI / 10.1200/jco.18.01042 Green published, Gold other
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Article YES1 Drives Lung Cancer Growth and Progression and Predicts Sensitivity to Dasatinib Garmendia, Irati; Pajares, Maria J.; Hermida-Prado, Francisco; Ajona, Daniel; Bertolo, Cristina; Sainz, Cristina; Lavin, Amaya; Remirez, Ana B.; Valencia, Karmele; Moreno, Haritz; Ferrer, Irene; Behrens, Carmen; Cuadrado, Myriam; Paz-Ares, Luis; Bustelo, X AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 1073-449X (2019) DOI / 10.1164/rccm.201807-1292oc Green published
Mentions   2   Wikipedia   10   News   0   Policy
Article Durvalumab, with or without tremelimumab, plus platinum-etoposide versus platinum-etoposide alone in first-line treatment of extensive-stage small-cell lung cancer (CASPIAN): updated results from a randomised, controlled, open-label, phase 3 trial Goldman, Jonathan W.; Dvorkin, Mikhail; Chen, Yuanbin; Reinmuth, Niels; Hotta, Katsuyuki; Trukhin, Dmytro; Statsenko, Galina; Hochmair, Maximilian J.; Ozguroglu, Mustafa; Ji, Jun Ho; Garassino, Marina Chiara; Voitko, Oleksandr; Poltoratskiy, Artem; Ponce, LANCET ONCOLOGY 1470-2045 (2021) DOI / 10.1016/s1470-2045(20)30539-8
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Review Precision Prevention and Cancer Interception: The New Challenges of Liquid Biopsy Jose Serrano, Maria; Carmen Garrido-Navas, Maria; Diaz Mochon, Juan Jose; Cristofanilli, Massimo; Gil-Bazo, Ignacio; Pauwels, Patrick; Malapelle, Umberto; Russo, Alessandro; Lorente, Jose A.; Ruiz-Rodriguez, Antonio J.; Paz-Ares, Luis G.; Vilar, Eduardo; R CANCER DISCOVERY 2159-8274 (2020) DOI / 10.1158/2159-8290.cd-20-0466
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Article Ramucirumab plus pembrolizumab in patients with previously treated advanced non-small-cell lung cancer, gastro-oesophageal cancer, or urothelial carcinomas (JVDF): a multicohort, non-randomised, open-label, phase 1a/b trial Herbst, Roy S.; Arkenau, Hendrik-Tobias; Santana-Davila, Rafael; Calvo, Emiliano; Paz-Ares, Luis; Cassier, Philippe A.; Bendell, Johanna; Penel, Nicolas; Krebs, Matthew G.; Martin-Liberal, Juan; Isambert, Nicolas; Soriano, Andres; Wermke, Martin; Cultrera, LANCET ONCOLOGY 1470-2045 (2019) DOI / 10.1016/s1470-2045(19)30458-9
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Article Pembrolizumab plus chemotherapy versus chemotherapy alone in patients with advanced non-small cell lung cancer without tumor PD-L1 expression: A pooled analysis of 3 randomized controlled trials Borghaei, Hossein; Langer, Corey J.; Paz-Ares, Luis; Rodriguez-Abreu, Delvys; Halmos, Balazs; Garassino, Marina C.; Houghton, Baerin; Kurata, Takayasu; Cheng, Ying; Lin, Jianxin; Pietanza, M. Catherine; Piperdi, Bilal; Gadgeel, Shirish M. CANCER 0008-543X (2020) DOI / 10.1002/cncr.33142 Green published, Gold other
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Article Nivolumab Versus Docetaxel in Previously Treated Patients With Advanced Non-Small-Cell Lung Cancer: Two-Year Outcomes From Two Randomized, Open-Label, Phase III Trials (CheckMate 017 and CheckMate 057) Horn, Leora; Spigel, David R.; Vokes, Everett E.; Holgado, Esther; Ready, Neal; Steins, Martin; Poddubskaya, Elena; Borghaei, Hossein; Felip, Enriqueta; Paz-Ares, Luis; Pluzanski, Adam; Reckamp, Karen L.; Burgio, Marco A.; Kohlhaeeufl, Martin; Waterhouse, JOURNAL OF CLINICAL ONCOLOGY 0732-183X (2017) DOI / 10.1200/jco.2017.74.3062 Green published
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Article Phase II Trial of Atezolizumab As First-Line or Subsequent Therapy for Patients With Programmed Death-Ligand 1-Selected Advanced Non-Small-Cell Lung Cancer (BIRCH) Peters, Solange; Gettinger, Scott; Johnson, Melissa L.; Janne, Pasi A.; Garassino, Marina C.; Christoph, Daniel; Toh, Chee Keong; Rizvi, Naiyer A.; Chaft, Jamie E.; Carcereny Costa, Enric; Patel, Jyoti D.; Chow, Laura Q. M.; Koczywas, Marianna; Ho, Cheryl; JOURNAL OF CLINICAL ONCOLOGY 0732-183X (2017) DOI / 10.1200/jco.2016.71.9476 Green published
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Article Phase 1 study of intravenous administration of the chimeric adenovirus enadenotucirev in patients undergoing primary tumor resection Garcia-Carbonero, Rocio; Salazar, Ramon; Duran, Ignacio; Osman-Garcia, Ignacio; Paz-Ares, Luis; Bozada, Juan M.; Boni, Valentina; Blanc, Christine; Seymour, Len; Beadle, John; Alvis, Simon; Champion, Brian; Calvo, Emiliano; Fisher, Kerry JOURNAL FOR IMMUNOTHERAPY OF CANCER (2017) DOI / 10.1186/s40425-017-0277-7 Gold DOAJ, Green published
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Article Updated guidelines for predictive biomarker testing in advanced non-small-cell lung cancer: a National Consensus of the Spanish Society of Pathology and the Spanish Society of Medical Oncology Garrido, P.; Conde, E.; De Castro, J.; Gomez-Roman, J. J.; Felip, E.; Pijuan, L.; Isla, D.; Sanz, J.; Paz-Ares, L.; Lopez-Rios, F. CLINICAL & TRANSLATIONAL ONCOLOGY 1699-048X (2020) DOI / 10.1007/s12094-019-02218-4 Gold other, Green published
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Article Assessment of a New ROS1 Immunohistochemistry Clone (SP384) for the Identification of ROS1 Rearrangements in Patients with Non-Small Cell Lung Carcinoma: the ROSING Study Conde, Esther; Hernandez, Susana; Martinez, Rebeca; Angulo, Barbara; De castro, Javier; Collazo-Lorduy, Ana; Jimenez, Beatriz; Muriel, Alfonso; Luis Mate, Jose; Moran, Teresa; Aranda, Ignacio; Massuti, Bartomeu; Rojo, Federico; Domine, Manuel; Sansano, Ire JOURNAL OF THORACIC ONCOLOGY 1556-0864 (2019) DOI / 10.1016/j.jtho.2019.07.005 Green published, Gold other
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Article CheckMate 171: A phase 2 trial of nivolumab in patients with previously treated advanced squamous non-small cell lung cancer, including ECOG PS 2 and elderly populations Felip, Enriqueta; Ardizzoni, Andrea; Ciuleanu, Tudor; Cobo, Manuel; Laktionov, Konstantin; Szilasi, Maria; Califano, Raffaele; Carcereny, Enric; Griffiths, Richard; Paz-Ares, Luis; Duchnowska, Renata; Alonso Garcia, Miriam; Isla, Dolores; Jassem, Jacek; Ap EUROPEAN JOURNAL OF CANCER 0959-8049 (2020) DOI / 10.1016/j.ejca.2019.11.019 Green published, Gold other
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Article Health-Related Quality of Life With Carboplatin-Paclitaxel or nab-Paclitaxel With or Without Pembrolizumab in Patients With Metastatic Squamous Non-Small-Cell Lung Cancer Mazieres, Julien; Kowalski, Dariusz; Luft, Alexander; Vicente, David; Tafreshi, Ali; Gumus, Mahmut; Laktionov, Konstantin; Hermes, Barbara; Cicin, Irfan; Rodriguez-Cid, Jeronimo; Wilson, Jonathan; Kato, Terufumi; Ramlau, Rodryg; Novello, Silvia; Reddy, Sre JOURNAL OF CLINICAL ONCOLOGY 0732-183X (2020) DOI / 10.1200/jco.19.01348 Green published
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Review ATLANTIS: a Phase III study of lurbinectedin/doxorubicin versus topotecan or cyclophosphamide/doxorubicin/vincristine in patients with small-cell lung cancer who have failed one prior platinum-containing line Farago, Anna F.; Drapkin, Benjamin J.; Antonio Lopez-Vilarino de Ramos, Jose; Galmarini, Carlos M.; Nunez, Rafael; Kahatt, Carmen; Paz-Ares, Luis FUTURE ONCOLOGY 1479-6694 (2019) DOI / 10.2217/fon-2018-0597 Green published
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Article Clinical utility of plasma-based digital next-generation sequencing in patients with advance-stage lung adenocarcinomas with insufficient tumor samples for tissue genotyping Zugazagoitia, J.; Ramos, I.; Trigo, J. M.; Palka, M.; Gomez-Rueda, A.; Jantus-Lewintre, E.; Camps, C.; Isla, D.; Iranzo, P.; Ponce-Aix, S.; Garcia-Campelo, R.; Provencio, M.; Franco, F.; Bernabe, R.; Juan-Vidal, O.; Felip, E.; De Castro, J.; Sanchez-Torres ANNALS OF ONCOLOGY 0923-7534 (2019) DOI / 10.1093/annonc/mdy512 Gold other
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Article Aligning digital CD8(+) scoring and targeted next-generation sequencing with programmed death ligand 1 expression: a pragmatic approach in early-stage squamous cell lung carcinoma Conde, Esther; Caminoa, Alejandra; Dominguez, Carolina; Calles, Antonio; Walter, Stefan; Angulo, Barbara; Sanchez, Elena; Alonso, Marta; Jimenez, Luis; Madrigal, Luis; Hernando, Florentino; Sanz-Ortega, Julian; Jimenez, Beatriz; Garrido, Pilar; Paz-Ares, L HISTOPATHOLOGY 0309-0167 (2018) DOI / 10.1111/his.13346 Gold other
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Article Three-Year Overall Survival with Durvalumab after Chemoradiotherapy in Stage III NSCLC-Update from PACIFIC Gray, Jhanelle E.; Villegas, Augusto; Daniel, Davey; Vicente, David; Murakami, Shuji; Hui, Rina; Kurata, Takayasu; Chiappori, Alberto; Lee, Ki Hyeong; Cho, Byoung Chul; Planchard, David; Paz-Ares, Luis; Faivre-Finn, Corinne; Vansteenkiste, Johan F.; Spigel JOURNAL OF THORACIC ONCOLOGY 1556-0864 (2020) DOI / 10.1016/j.jtho.2019.10.002 Gold other, Green accepted
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Article Antitumor activity of an engineered decoy receptor targeting CLCF1-CNTFR signaling in lung adenocarcinoma Kim, Jun W.; Marquez, Cesar P.; Kostyrko, Kaja; Koehne, Amanda L.; Marini, Kieren; Simpson, David R.; Lee, Alex G.; Leung, Stanley G.; Sayles, Leanne C.; Shrager, Joseph; Ferrer, Irene; Paz-Ares, Luis; Gephart, Melanie Hayden; Vicent, Silvestre; Cochran, J NATURE MEDICINE 1078-8956 (2019) DOI / 10.1038/s41591-019-0612-2 Green accepted
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Review Lung cancer: current therapies and new targeted treatments Hirsch, Fred R.; Scagliotti, Giorgio V.; Mulshine, James L.; Kwon, Regina; Curran, Walter J.; Wu, Yi-Long; Paz-Ares, Luis LANCET 0140-6736 (2017) DOI / 10.1016/s0140-6736(16)30958-8
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Article Impact of prior chemoradiotherapy-related variables on outcomes with durvalumab in unresectable Stage III NSCLC (PACIFIC) Faivre-Finn, Corinne; Spigel, David R.; Senan, Suresh; Langer, Corey; Perez, Bradford A.; Ozguroglu, Mustafa; Daniel, Davey; Villegas, Augusto; Vicente, David; Hui, Rina; Murakami, Shuji; Paz-Ares, Luis; Broadhurst, Helen; Wadsworth, Catherine; Dennis, Phi LUNG CANCER 0169-5002 (2021) DOI / 10.1016/j.lungcan.2020.11.024 Hybrid
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Article Outcomes with durvalumab by tumour PD-L1 expression in unresectable, stage III non-small-cell lung cancer in the PACIFIC trial Paz-Ares, L.; Spira, A.; Raben, D.; Planchard, D.; Cho, B. C.; Ozguroglu, M.; Daniel, D.; Villegas, A.; Vicente, D.; Hui, R.; Murakami, S.; Spigel, D.; Senan, S.; Langer, C. J.; Perez, B. A.; Boothman, A-M; Broadhurst, H.; Wadsworth, C.; Dennis, P. A.; Ant ANNALS OF ONCOLOGY 0923-7534 (2020) DOI / 10.1016/j.annonc.2020.03.287 Bronze
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Review Challenges and opportunities of cfDNA analysis implementation in clinical practice: Perspective of the International Society of Liquid Biopsy (ISLB) Rolfo, Christian; Cardona, Andres F.; Cristofanilli, Massimo; Paz-Ares, Luis; Diaz Mochon, Juan Jose; Duran, Ignacio; Raez, Luis E.; Russo, Alessandro; Lorente, Jose A.; Malapelle, Umberto; Gil-Bazo, Ignacio; Jantus-Lewintre, Eloisa; Pauwels, Patrick; Mok, CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY 1040-8428 (2020) DOI / 10.1016/j.critrevonc.2020.102978
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Article Four-Year Survival With Durvalumab After Chemoradiotherapy in Stage III NSCLC-an Update From the PACIFIC Trial Faivre-Finn, Corinne; Vicente, David; Kurata, Takayasu; Planchard, David; Paz-Ares, Luis; Vansteenkiste, Johan F.; Spigel, David R.; Garassino, Marina C.; Reck, Martin; Senan, Suresh; Naidoo, Jarushka; Rimner, Andreas; Wu, Yi-Long; Gray, Jhanelle E.; Ozgur JOURNAL OF THORACIC ONCOLOGY 1556-0864 (2021) DOI / 10.1016/j.jtho.2020.12.015 Gold other
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Article Outcomes in patients with aggressive or refractory disease from REVEL: A randomized phase III study of docetaxel with ramucirumab or placebo for second-line treatment of stage IV non-small-cell lung cancer Reck, Martin; Paz-Ares, Luis; Bidoli, Paolo; Cappuzzo, Federico; Dakhil, Shaker; Moro-Sibilot, Denis; Borghaei, Hossein; Johnson, Melissa; Jotte, Robert; Pennell, Nathan A.; Shepherd, Frances A.; Tsao, Anne; Thomas, Michael; Carter, Gebra Cuyun; Chan-Diehl LUNG CANCER 0169-5002 (2017) DOI / 10.1016/j.lungcan.2017.07.038 Gold other
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Article A Randomized, Placebo-Controlled Trial of Pembrolizumab Plus Chemotherapy in Patients With Metastatic Squamous NSCLC: Protocol-Specified Final Analysis of KEYNOTE-407 Paz-Ares, Luis; Vicente, David; Tafreshi, Ali; Robinson, Andrew; Parra, Hector Soto; Mazieres, Julien; Hermes, Barbara; Cicin, Irfan; Medgyasszay, Balazs; Rodriguez-Cid, Jeronimo; Okamoto, Isamu; Lee, Sungsook; Ramlau, Rodryg; Vladimirov, Vladimir; Cheng, JOURNAL OF THORACIC ONCOLOGY 1556-0864 (2020) DOI / 10.1016/j.jtho.2020.06.015 Bronze
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Article Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting TGF-beta and PD-L1, in Second-Line Treatment of Patients With NSCLC: Results From an Expansion Cohort of a Phase 1 Trial Paz-Ares, Luis; Kim, Tae Min; Vicente, David; Felip, Enriqueta; Lee, Dae Ho; Lee, Ki Hyeong; Lin, Chia-Chi; Jose Flor, Maria; Di Nicola, Massimo; Maria Alvarez, Rosa; Dussault, Isabelle; Helwig, Christoph; Ojalvo, Laureen S.; Gulley, James L.; Cho, Byoung JOURNAL OF THORACIC ONCOLOGY 1556-0864 (2020) DOI / 10.1016/j.jtho.2020.03.003
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Article An Fc-free EGFR-specific 4-1BB-agonistic Trimerbody Displays Broad Antitumor Activity in Humanized Murine Cancer Models without Toxicity Compte, Marta; Harwood, Seandean L.; Erce-Llamazares, Ainhoa; Tapia-Galisteo, Antonio; Romero, Eduardo; Ferrer, Irene; Garrido-Martin, Eva M.; Enguita, Ana B.; Ochoa, Maria C.; Blanco, Belen; Oteo, Marta; Merino, Nekane; Nehme-Alvarez, Daniel; Hangiu, Oana CLINICAL CANCER RESEARCH 1078-0432 (2021) DOI / 10.1158/1078-0432.ccr-20-4625 Bronze
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Review KRAS-Mutant non-small cell lung cancer: From biology to therapy Ferrer, Irene; Zugazagoitia, Jon; Herbertz, Stephan; John, William; Paz-Ares, Luis; Schmid-Bindert, Gerald LUNG CANCER 0169-5002 (2018) DOI / 10.1016/j.lungcan.2018.07.013 Gold other
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Article Results From the Phase III Randomized Trial of Onartuzumab Plus Erlotinib Versus Erlotinib in Previously Treated Stage IIIB or IV Non-Small-Cell Lung Cancer: METLung Spigel, David R.; Edelman, Martin J.; O'Byrne, Kenneth; Paz-Ares, Luis; Mocci, Simonetta; Phan, See; Shames, David S.; Smith, Dustin; Yu, Wei; Paton, Virginia E.; Mok, Tony JOURNAL OF CLINICAL ONCOLOGY 0732-183X (2017) DOI / 10.1200/jco.2016.69.2160 Green published
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Article Phase I Study of the Efficacy and Safety of Ramucirumab in Combination with Osimertinib in Advanced T790M-positive EGFR-mutant Non-small Cell Lung Cancer Yu, Helena A.; Paz-Ares, Luis G.; Yang, James Chih-Hsin; Lee, Ki Hyeong; Garrido, Pilar; Park, Keunchil; Kim, Joo-Hang; Lee, Dae Ho; Mao, Huzhang; Wijayawardana, Sameera R.; Gao, Ling; Hozak, Rebecca R.; Chao, Bo H.; Planchard, David CLINICAL CANCER RESEARCH 1078-0432 (2021) DOI / 10.1158/1078-0432.ccr-20-1690
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Article Safety, Tolerability, and Potential Clinical Activity of a Glucocorticoid-Induced TNF Receptor-Related Protein Agonist Alone or in Combination With Nivolumab for Patients With Advanced Solid Tumors A Phase 1/2a Dose-Escalation and Cohort-Expansion Clinical Heinhuis, Kimberley M.; Carlino, Matteo; Joerger, Markus; Di Nicola, Massimo; Meniawy, Tarek; Rottey, Sylvie; Moreno, Victor; Gazzah, Anas; Delord, Jean-Pierre; Paz-Ares, Luis; Britschgi, Christian; Schilder, Russell J.; O'Byrne, Kenneth; Curigliano, Giuse JAMA ONCOLOGY 2374-2437 (2020) DOI / 10.1001/jamaoncol.2019.3848 Bronze, Green published
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Article SARS-CoV-2 infection in cancer patients undergoing active treatment: analysis of clinical features and predictive factors for severe respiratory failure and death Yarza, Ramon; Bover, Mateo; Paredes, Diana; Lopez-Lopez, Flora; Jara-Casas, Diego; Castelo-Loureiro, Alicia; Baena, Javier; Maria Mazarico, Jose; Dolores Folgueira, Maria; Angeles Melendez-Carmo, Maria; Reyes, Alhena; Lumbreras, Carlos; Paz-Ares, Luis; Dia EUROPEAN JOURNAL OF CANCER 0959-8049 (2020) DOI / 10.1016/j.ejca.2020.06.001 Green published, Bronze
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Article First-line nivolumab plus ipilimumab with two cycles of chemotherapy versus chemotherapy alone (four cycles) in advanced non-small-cell lung cancer: CheckMate 9LA 2-year update Reck, M.; Ciuleanu, T. -E.; Cobo, M.; Schenker, M.; Zurawski, B.; Menezes, J.; Richardet, E.; Bennouna, J.; Felip, E.; Juan-Vidal, O.; Alexandru, A.; Sakai, H.; Lingua, A.; Reyes, F.; Souquet, P. -J.; De Marchiy, P.; Martin, C.; Perol, M.; Scherpereel, A.; ESMO OPEN (2021) DOI / 10.1016/j.esmoop.2021.100273 Green published, Gold
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Article Sequencing of therapy following first-line afatinib in patients with EGFR mutation-positive non-small cell lung cancer Park, Keunchil; Bennouna, Jaafar; Boyer, Michael; Hida, Toyoaki; Hirsh, Vera; Kato, Terufumi; Lug, Shun; Mok, Tony; Nakagawa, Kazuhiko; O'Byrne, Kenneth; Paz-Ares, Luis; Schuler, Martin; Sibilotru, Denis Moro; Tan, Eng-Huat; Tanaka, Hiroshi; We, Yi-Long; Y LUNG CANCER 0169-5002 (2019) DOI / 10.1016/j.lungcan.2019.04.014 Green published, Gold other
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Article Patient-reported outcomes with durvalumab by PD-L1 expression and prior chemoradiotherapy-related variables in unresectable, stage III non-small-cell lung cancer Garassino, Marina C.; Paz-Ares, Luis; Hui, Rina; Faivre-Finn, Corinne; Spira, Alex; Planchard, David; Ozguroglu, Mustafa; Daniel, Davey; Vicente, David; Murakami, Shuji; Langer, Corey; Senan, Suresh; Spigel, David; Ryden, Anna; Zhang, Yiduo; O'Brien, Cathy FUTURE ONCOLOGY 1479-6694 (2021) DOI / 10.2217/fon-2020-1102 Gold other
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Article Phase I clinical and pharmacokinetic study of PM01183 (a tetrahydroisoquinoline, Lurbinectedin) in combination with gemcitabine in patients with advanced solid tumors Paz-Ares, Luis; Forster, Martin; Boni, Valentina; Szyldergemajn, Sergio; Corral, Jesus; Turnbull, Samantha; Cubillo, Antonio; Fernandez Teruel, Carlos; Lopez Calderero, Iker; Siguero, Mariano; Bohan, Patrick; Calvo, Emiliano INVESTIGATIONAL NEW DRUGS 0167-6997 (2017) DOI / 10.1007/s10637-016-0410-3 Green submitted
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Article Tumor mutational burden assessment in non-small-cell lung cancer samples: results from the TMB2 harmonization project comparing three NGS panels Ramos-Paradas, Javier; Hernandez-Prieto, Susana; Lora, David; Sanchez, Elena; Rosado, Aranzazu; Caniego-Casas, Tamara; Carrizo, Nuria; Belen Enguita, Ana; Teresa Munoz-Jimenez, Maria; Rodriguez, Borja; Perez-Gonzalez, Urbicio; Gomez-Sanchez, David; Ferrer, JOURNAL FOR IMMUNOTHERAPY OF CANCER (2021) DOI / 10.1136/jitc-2020-001904
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Article Combined PIK3CA and FGFR Inhibition With Alpelisib and Infigratinib in Patients With PIK3CA-Mutant Solid Tumors, With or Without FGFR Alterations Hyman, David M.; Tran, Ben; Paz-Ares, Luis; Machiels, Jean-Pascal; Schellens, Jan H.; Bedard, Philippe L.; Campone, Mario; Cassier, Philippe A.; Sarantopoulos, John; Vaishampayan, Ulka; Chugh, Rashmi; Mahipal, Amit; Lockhart, A. Craig; Sessa, Cristiana; Za JCO PRECISION ONCOLOGY (2019) DOI / 10.1200/po.19.00221 Green published, Gold other
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Review 30 Immunotherapy in advanced NSCLC - from the 'tsunami' of therapeutic knowledge to a clinical practice algorithm: results from an international expert panel meeting of the Italian Association of Thoracic Oncology (AIOT) de Marinis, Filippo; Ciardiello, Fortunato; Baas, Paul; Crino, Lucio; Giaccone, Giuseppe; Grossi, Francesco; Hellmann, Matthew D.; Mok, Tony S. K.; Lena, Herve; Paz-Ares, Luis; Rodriguez-Abreu, Delvys; Von Pavel, Joachim; Gridelli, Cesare ESMO OPEN (2018) DOI / 10.1136/esmoopen-2017-000298 Gold DOAJ, Green published
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Review First-line immune checkpoint blockade for advanced non-small-cell lung cancer: Travelling at the speed of light Ackermann, Christoph Jakob; Reck, Martin; Paz-Ares, Luis; Barlesi, Fabrice; Califano, Raffaele LUNG CANCER 0169-5002 (2019) DOI / 10.1016/j.lungcan.2019.06.007
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Article Genomic Profiling of HER2-Positive Gastric Cancer: PI3K/Akt/mTOR Pathway as Predictor of Outcomes in HER2-Positive Advanced Gastric Cancer Treated with Trastuzumab Diaz-Serrano, Asuncion; Angulo, Barbara; Dominguez, Carolina; Pazo-Cid, Roberto; Salud, Antonieta; Jimenez-Fonseca, Paula; Leon, Ana; Carmen Galan, Maria; Alsina, Maria; Rivera, Fernando; Plaza, J. Carlos; Paz-Ares, Luis; Lopez-Rios, Fernando; Gomez-Martin ONCOLOGIST 1083-7159 (2018) DOI / 10.1634/theoncologist.2017-0379 Green published, Bronze
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Letter Incidence, predictors and prognostic significance of thromboembolic disease in patients with advanced ALK-rearranged non-small cell lung cancer Zugazagoitia, Jon; Biosca, Mercedes; Oliveira, Julio; Eugenia Olmedo, Maria; Domine, Manuel; Nadal, Ernest; Carlos Ruffinelli, Jose; Munoz, Nerea; Maria Luna, Ana; Hernandez, Berta; Martinez, Maite; Gallego, Iria; Martinez de Castro, Eva; Font, Carme; Calv EUROPEAN RESPIRATORY JOURNAL 0903-1936 (2018) DOI / 10.1183/13993003.02431-2017 Bronze
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Article Lurbinectedin in the treatment of relapsed small cell lung cancer Baena, Javier; Modrego, Andrea; Zeaiter, Ali; Kahatt, Carmen; Alfaro, Vicente; Jimenez-Aguilar, Elizabeth; Mazarico, Jose Maria; Paz-Ares, Luis FUTURE ONCOLOGY 1479-6694 (2021) DOI / 10.2217/fon-2020-1212
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Article Patient-reported outcomes from STARTRK-2: a global phase II basket study of entrectinib for ROS1 fusion-positive non-small-cell lung cancer and NTRK fusion-positive solid tumours Paz-Ares, L.; Barlesi, F.; Siena, S.; Ahn, M-J; Drilon, A.; Conley, A.; Rolfo, C.; Wolf, J.; Seto, T.; Doebele, R.; Kapre, A.; Chen, D.; McCallum, S.; Osborne, S.; Demetri, G. ESMO OPEN (2021) DOI / 10.1016/j.esmoop.2021.100113 Green published, Gold
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Article LungBEAM: A prospective multicenter study to monitor stage IV NSCLC patients with EGFR mutations using BEAMing technology Garrido, Pilar; Paz-Ares, Luis; Majem, Margarita; Moran, Teresa; Trigo, Jose Manuel; Bosch-Barrera, Joaquim; Garcia-Campelo, Rosario; Gonzalez-Larriba, Jose Luis; Sanchez-Torres, Jose Miguel; Isla, Dolores; Vinolas, Nuria; Camps, Carlos; Insa, Amelia; Juan CANCER MEDICINE 2045-7634 (2021) DOI / 10.1002/cam4.4135 Gold, Green published
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Review Biological therapies in nonsmall cell lung cancer Zugazagoitia, Jon; Molina-Pinelo, Sonia; Lopez-Rios, Fernando; Paz-Ares, Luis EUROPEAN RESPIRATORY JOURNAL 0903-1936 (2017) DOI / 10.1183/13993003.01520-2016 Bronze
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Article High risk of thrombosis in patients with advanced lung cancer harboring rearrangements in ROS1 Munoz-Unceta, Nerea; Zugazagoitia, Jon; Manzano, Arancha; Jimenez-Aguilar, Elisabeth; Olmedo, Maria E.; Cacho, Juan D.; Oliveira, Julio; Domine, Manuel; Ortega-Moran, Laura; Aguado, Carlos; Luna, Ana M.; Fernandez, Lourdes; Perez, Javier; Font, Carme; Salv EUROPEAN JOURNAL OF CANCER 0959-8049 (2020) DOI / 10.1016/j.ejca.2020.10.002
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Article A randomized, phase 2 evaluation of the CHK1 inhibitor, LY2603618, administered in combination with pemetrexed and cisplatin in patients with advanced nonsquamous non-small cell lung cancer Wehler, Thomas; Thomas, Micheal; Schumann, Chirstian; Bosch-Barrera, Joaquim; Segarra, Nuria Vinolas; Dickgreber, Nicolas J.; Dalhoff, Klaus; Sebastian, Martin; Jaime, Jesus Corral; Alonso, Miriam; Hynes, Scott M.; Lin, JI; Hurt, Karla; Lin, Aimee Bence; C LUNG CANCER 0169-5002 (2017) DOI / 10.1016/j.lungcan.2017.03.001
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Review Molecular and Immune Biomarker Testing in Squamous-Cell Lung Cancer: Effect of Current and Future Therapies and Technologies Hirsch, Fred R.; Kerr, Keith M.; Bunn, Paul A., Jr.; Kim, Edward S.; Obasaju, Coleman; Perol, Maurice; Bonomi, Philip; Bradley, Jeffrey D.; Gandara, David; Jett, James R.; Langer, Corey J.; Natale, Ronald B.; Novello, Silvia; Paz-Ares, Luis; Ramalingam, Su CLINICAL LUNG CANCER 1525-7304 (2018) DOI / 10.1016/j.cllc.2018.03.014 Green submitted, Hybrid
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Article RELAY Subgroup Analyses by EGFR Ex19del and Ex21L858R Mutations for Ramucirumab Plus Erlotinib in Metastatic Non-Small Cell Lung Cancer Nakagawa, Kazuhiko; Nadal, Ernest; Garon, Edward B.; Nishio, Makoto; Seto, Takashi; Yamamoto, Nobuyuki; Park, Keunchil; Shih, Jin-Yuan; Paz-Ares, Luis; Frimodt-Moller, Bente; Zimmermann, Annamaria H.; Wijayawardana, Sameera; Visseren-Grul, Carla; Reck, Mar CLINICAL CANCER RESEARCH 1078-0432 (2021) DOI / 10.1158/1078-0432.ccr-21-0273 Hybrid
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Article FGFR1 and FGFR4 oncogenicity depends on n-cadherin and their co-expression may predict FGFR-targeted therapy efficacy Quintanal-Villalonga, Alvaro; Ferrer, Irene; Guruceaga, Elizabeth; Cirauqui, Cristina; Marrugal, Angela; Ojeda, Laura; Garcia, Santiago; Zugazagoitia, Jon; Munoz-Galvan, Sandra; Lopez-Rios, Fernando; Montuenga, Luis; Vicent, Silvestre; Molina-Pinelo, Sonia EBIOMEDICINE 2352-3964 (2020) DOI / 10.1016/j.ebiom.2020.102683 Green published, Gold
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Review Second-Line Treatment Options in Non-Small-Cell Lung Cancer: Report From an International Experts Panel Meeting of the Italian Association of Thoracic Oncology Gridelli, Cesare; Baas, Paul; Barlesi, Fabrice; Ciardiello, Fortunato; Crino, Lucio; Felip, Enriqueta; Gadgeel, Shirish; Papadimitrakopoulou, Vali; Paz-Ares, Luis; Planchard, David; Perol, Maurice; Hanna, Nasser; Sgambato, Assunta; Casaluce, Francesca; de CLINICAL LUNG CANCER 1525-7304 (2018) DOI / 10.1016/j.cllc.2017.12.010 Green published
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Article Clinical utility of plasma-based digital next-generation sequencing in oncogene-driven non-small-cell lung cancer patients with tyrosine kinase inhibitor resistance Zugazagoitia, Jon; Gomez-Rueda, Ana; Jantus-Lewintre, Eloisa; Isla, Dolores; Camps, Carlos; Ramos, Inmaculada; Manuel Trigo, Jose; Bernabe, Reyes; Juan-Vidal, Oscar; Miguel Sanchez-Torres, Jose; Garcia-Campelo, Rosario; Provencio, Mariano; Felip, Enriqueta LUNG CANCER 0169-5002 (2019) DOI / 10.1016/j.lungcan.2019.05.032
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Article Targeting HER3, a Catalytically Defective Receptor Tyrosine Kinase, Prevents Resistance of Lung Cancer to a Third-Generation EGFR Kinase Inhibitor Romaniello, Donatella; Marrocco, Ilaria; Belugali Nataraj, Nishanth; Ferrer, Irene; Drago-Garcia, Diana; Vaknin, Itay; Oren, Roni; Lindzen, Moshit; Ghosh, Soma; Kreitman, Matthew; Kittel, Jeanette Clarissa; Gaborit, Nadege; Bergado Baez, Gretchen; Sanchez, CANCERS (2020) DOI / 10.3390/cancers12092394 Gold DOAJ, Green published
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Review Strategies to design clinical studies to identify predictive biomarkers in cancer research Perez-Gracia, Jose Luis; Sanmamed, Miguel F.; Bosch, Ana; Patino-Garcia, Ana; Schalper, Kurt A.; Segura, Victor; Bellmunt, Joaquim; Tabernero, Josep; Sweeney, Christopher J.; Choueiri, Toni K.; Martin, Miguel; Pablo Fusco, Juan; Esperanza Rodriguez-Ruiz, M CANCER TREATMENT REVIEWS 0305-7372 (2017) DOI / 10.1016/j.ctrv.2016.12.005 Gold other, Green published
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Article Abemaciclib in Combination with Single-Agent Options in Patients with Stage IV Non-Small Cell Lung Cancer: A Phase Ib Study Kim, Edward S.; Kelly, Karen; Paz-Ares, Luis G.; Garrido, Pilar; Jalal, Shadia; Mahadevan, Daruka; Gutierrez, Martin; Provencio, Mariano; Schaefer, Eric; Shaheen, Monte; Johnston, Erica L.; Turner, P. Kellie; Kambhampati, Siva Rama Prasad; Beckmann, Richar CLINICAL CANCER RESEARCH 1078-0432 (2018) DOI / 10.1158/1078-0432.ccr-18-0651 Bronze, Green published
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Article Fra-2-expressing macrophages promote lung fibrosis Ucero, Alvaro C.; Bakiri, Latifa; Roediger, Ben; Suzuki, Masakatsu; Jimenez, Maria; Mandal, Pratyusha; Braghetta, Paola; Bonaldo, Paolo; Paz-Ares, Luis; Fustero-Torre, Coral; Ximenez-Embun, Pilar; Isabel Hernandez, Ana; Megias, Diego; Wagner, Erwin F. JOURNAL OF CLINICAL INVESTIGATION 0021-9738 (2019) DOI / 10.1172/jci125366 Green published, Bronze
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Review First-line immune checkpoint inhibitors for extensive stage small-cell lung cancer: clinical developments and future directions Ortega-Franco, A.; Ackermann, C.; Paz-Ares, L.; Califano, R. ESMO OPEN (2021) DOI / 10.1016/j.esmoop.2020.100003 Gold DOAJ, Green published
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Article Long-term survival in advanced non-squamous NSCLC patients treated with first-line bevacizumab-based therapy De Castro, J.; Gonzalez-Larriba, J. L.; Vazquez, S.; Massuti, B.; Sanchez-Torres, J. M.; Domine, M.; Garrido, P.; Calles, A.; Artal, A.; Collado, R.; Garcia, R.; Sereno, M.; Majem, M.; Macias, J. A.; Juan, O.; Gomez-Codina, J.; Hernandez, B.; Lazaro, M.; O CLINICAL & TRANSLATIONAL ONCOLOGY 1699-048X (2017) DOI / 10.1007/s12094-016-1527-8
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Review Predictive biomarkers for response to EGFR-directed monoclonal antibodies for advanced squamous cell lung cancer Bonomi, P. D.; Gandara, D.; Hirsch, F. R.; Kerr, K. M.; Obasaju, C.; Paz-Ares, L.; Bellomo, C.; Bradley, J. D.; Bunn, P. A., Jr.; Culligan, M.; Jett, J. R.; Kim, E. S.; Langer, C. J.; Natale, R. B.; Novello, S.; Perol, M.; Ramalingam, S. S.; Reck, M.; Reyn ANNALS OF ONCOLOGY 0923-7534 (2018) DOI / 10.1093/annonc/mdy196 Green published, Gold other
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Review Meta-analysis of individual patient safety data from six randomized, placebo-controlled trials with the antiangiogenic VEGFR2-binding monoclonal antibody ramucirumab Arnold, D.; Fuchs, C. S.; Tabernero, J.; Ohtsu, A.; Zhu, A. X.; Garon, E. B.; Mackey, J. R.; Paz-Ares, L.; Baron, A. D.; Okusaka, T.; Yoshino, T.; Yoon, H. H.; Das, M.; Ferry, D.; Zhang, Y.; Lin, Y.; Binder, P.; Sashegyi, A.; Chau, I. ANNALS OF ONCOLOGY 0923-7534 (2017) DOI / 10.1093/annonc/mdx514 Green published, Gold other
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Article Defining aggressive or early progressing nononcogene-addicted non-small-cell lung cancer: a separate disease entity? Reck, Martin; Kerr, Keith M.; Grohe, Christian; Manegold, Christian; Pavlakis, Nick; Paz-Ares, Luis; Huber, Rudolf M.; Popat, Sanjay; Thatcher, Nick; Park, Keunchil; Hilberg, Frank; Barrueco, Jose; Kaiser, Rolf FUTURE ONCOLOGY 1479-6694 (2019) DOI / 10.2217/fon-2018-0948 Gold other
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Article First-In-Human Phase I Study Of A Dual mTOR Kinase And DNA-PK Inhibitor (CC-115) In Advanced Malignancy Munster, Pamela; Mita, Monica; Mahipal, Amit; Nemunaitis, John; Massard, Christophe; Mikkelsen, Tom; Cruz, Cristina; Paz-Ares, Luis; Hidalgo, Manuel; Rathkopf, Dana; Blumenschein, George, Jr.; Smith, David C.; Eichhorst, Barbara; Cloughesy, Tim; Filvaroff, CANCER MANAGEMENT AND RESEARCH 1179-1322 (2019) DOI / 10.2147/cmar.s208720 Gold DOAJ, Green published
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Article Impact of DLK1-DIO3 imprinted cluster hypomethylation in smoker patients with lung cancer Molina-Pinelo, Sonia; Salinas, Ana; Moreno-Mata, Nicolas; Ferrer, Irene; Suarez, Rocio; Andres-Leon, Eduardo; Rodriguez-Paredes, Manuel; Gutekunst, Julian; Jantus-Lewintre, Eloisa; Camps, Carlos; Carnero, Amancio; Paz-Ares, Luis ONCOTARGET 1949-2553 (2018) DOI / 10.18632/oncotarget.10611 Green submitted, Green published, Gold
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Article Enhanced Cytotoxic Activity of Mitochondrial Mechanical Effectors in Human Lung Carcinoma H520 Cells: Pharmaceutical Implications for Cancer Therapy Gonzalez Rubio, Sergio; Montero Pastor, Nuria; Garcia, Carolina; Almendro-Vedia, Victor G.; Ferrer, Irene; Natale, Paolo; Paz-Ares, Luis; Pilar Lillo, M.; Lopez-Montero, Ivan FRONTIERS IN ONCOLOGY 2234-943X (2018) DOI / 10.3389/fonc.2018.00514 Green published, Green accepted, Gold
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Article Randomized, Double-Blind Phase Ib/III Study of Erlotinib With Ramucirumab or Placebo in Previously Untreated EGFR-Mutant Metastatic Non-Small-Cell Lung Cancer (RELAY): Phase Ib Results Reck, Martin; Garon, Edward B.; Paz-Ares, Luis; Ponce, Santiago; Corral Jaime, Jesus; Juan, Oscar; Nadal, Ernest; Kiura, Katsuyuki; Widau, Ryan C.; He, Shuang; Dalal, Rita; Lee, Pablo; Nakagawa, Kazuhiko CLINICAL LUNG CANCER 1525-7304 (2018) DOI / 10.1016/j.cllc.2017.11.003 Gold other
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Article MAP17 predicts sensitivity to platinum-based therapy, EGFR inhibitors and the proteasome inhibitor bortezomib in lung adenocarcinoma Ferrer, Irene; Quintanal-Villalonga, Alvaro; Molina-Pinelo, Sonia; Manuel Garcia-Heredia, Jose; Perez, Marco; Suarez, Rocio; Ponce-Aix, Santiago; Paz-Ares, Luis; Carnero, Amancio JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2018) DOI / 10.1186/s13046-018-0871-7 Gold DOAJ, Green published
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Article Treatment Rationale and Study Design for the RELAY Study: A Multicenter, Randomized, Double-Blind Study of Erlotinib With Ramucirumab or Placebo in Patients With Epidermal Growth Factor Receptor Mutation-Positive Metastatic Non-Small-Cell Lung Cancer Garon, Edward B.; Reck, Martin; Paz-Ares, Luis; Ponce, Santiago; Corral Jaime, Jesus; Juan, Oscar; Nadal, Ernest; Lee, Pablo; Dalal, Rita; Liu, Jingyi; He, Shuang; Treat, Joseph; Nakagawa, Kazuhiko CLINICAL LUNG CANCER 1525-7304 (2017) DOI / 10.1016/j.cllc.2016.05.023
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Review A consensus statement on the gender perspective in lung cancer Isla, D.; Majem, M.; Vinolas, N.; Artal, A.; Blasco, A.; Felip, E.; Garrido, P.; Remon, J.; Baquedano, M.; Borras, J. M.; Die Trill, M.; Garcia-Campelo, R.; Juan, O.; Leon, C.; Lianes, P.; Lopez-Rios, F.; Molins, L.; Planchuelo, M. A.; Cobo, M.; Paz-Ares, CLINICAL & TRANSLATIONAL ONCOLOGY 1699-048X (2017) DOI / 10.1007/s12094-016-1578-x Green accepted
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Article Patient-reported outcomes with first-line durvalumab plus platinum-etoposide versus platinum-etoposide in extensive-stage small-cell lung cancer (CASPIAN): a randomized, controlled, open-label, phase III study Goldman, Jonathan W.; Garassino, Marina Chiara; Chen, Yuanbin; Ozguroglu, Mustafa; Dvorkin, Mikhail; Trukhin, Dmytro; Statsenko, Galina; Hotta, Katsuyuki; Ji, Jun Ho; Hochmair, Maximilian J.; Voitko, Oleksandr; Havel, Libor; Poltoratskiy, Artem; Losonczy, LUNG CANCER 0169-5002 (2020) DOI / 10.1016/j.lungcan.2020.09.003 Green accepted, Gold other
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Article Predicting immunotherapy outcomes under therapy in patients with advanced NSCLC using dNLR and its early dynamics Mezquita, Laura; Preeshagul, Isabel; Auclin, Edouard; Saravia, Diana; Hendriks, Lizza; Rizvi, Hira; Park, Wungki; Nadal, Ernest; Martin-Romano, Patricia; Ruffinelli, Jose C.; Ponce, Santiago; Audigier-Valette, Clarisse; Carnio, Simona; Blanc-Durand, Felix; EUROPEAN JOURNAL OF CANCER 0959-8049 (2021) DOI / 10.1016/j.ejca.2021.03.011 Green published
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Article First-line afatinib for advanced EGFRm plus NSCLC: Analysis of long-term responders in the LUX-Lung 3, 6, and 7 trials Schuler, Martin; Paz-Ares, Luis; Sequist, Lecia, V; Hirsh, Vera; Lee, Ki Hyeong; Wu, Yi-Long; Lu, Shun; Zho, Caicun; Feng, Jifeng; Ellis, Stuart H.; Samuelsen, Carl H.; Tang, Wenbo; Marten, Angela; Ehrnrooth, Eva; Park, Keunchil; Yang, James Chih-Hsin LUNG CANCER 0169-5002 (2019) DOI / 10.1016/j.lungcan.2019.04.006 Gold other
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Review PD-(L)1 Inhibitors as Monotherapy for the First-Line Treatment of Non-Small-Cell Lung Cancer Patients with High PD-L1 Expression: A Network Meta-Analysis Majem, Margarita; Cobo, Manuel; Isla, Dolores; Marquez-Medina, Diego; Rodriguez-Abreu, Delvys; Casal-Rubio, Joaquin; Moran-Bueno, Teresa; Bernabe-Caro, Reyes; Perez-Parente, Diego; Ruiz-Gracia, Pedro; Arroyo, Marta Marina; Paz-Ares, Luis JOURNAL OF CLINICAL MEDICINE (2021) DOI / 10.3390/jcm10071365 Gold DOAJ, Green published
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Article First-line afatinib vs gefitinib for patients with EGFR mutation-positive NSCLC (LUX-Lung 7): impact of afatinib dose adjustment and analysis of mode of initial progression for patients who continued treatment beyond progression Schuler, Martin; Tan, Eng-Huat; O'Byrne, Kenneth; Zhang, LI; Boyer, Michael; Mok, Tony; Hirsh, Vera; Yang, James Chih-Hsin; Lee, Ki Hyeong; Lu, Shun; Shi, Yuankai; Kim, Sang-We; Laskin, Janessa; Kim, Dong-Wan; Arvis, Catherine Dubos; Kolbeck, Karl; Massey, JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY 0171-5216 (2019) DOI / 10.1007/s00432-019-02862-x Green published, Gold other
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Review Second-line Treatment of Non-Small Cell Lung Cancer: Focus on the Clinical Development of Dacomitinib Zugazagoitia, Jon; Diaz, Asuncion; Jimenez, Elisabeth; Nunez, Juan Antonio; Iglesias, Lara; Ponce-Aix, Santiago; Paz-Ares, Luis FRONTIERS IN MEDICINE (2017) DOI / 10.3389/fmed.2017.00036 Gold DOAJ, Green published
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Article Safety Analyses of Pemetrexed-cisplatin and Pemetrexed Maintenance Therapies in Patients With Advanced Non-squamous NSCLC: Retrospective Analyses From 2 Phase III Studies Langer, Corey J.; Paz-Ares, Luis G.; Wozniak, Antoinette J.; Gridelli, Cesare; de Marinis, Filippo; Pujol, Jean-Louis; San Antonio, Belen; Chen, Jian; Liu, Jingyi; Oton, Ana B.; Visseren-Grul, Carla; Scagliotti, Giorgio V. CLINICAL LUNG CANCER 1525-7304 (2017) DOI / 10.1016/j.cllc.2017.04.003
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Review Durvalumab in NSCLC: latest evidence and clinical potential Munoz-Unceta, Nerea; Burgueno, Isabel; Jimenez, Elizabeth; Paz-Ares, Luis THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY 1758-8340 (2018) DOI / 10.1177/1758835918804151 Gold DOAJ, Green published
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Article Prognostic Significance of Liver Metastasis in Durvalumab-Treated Lung Cancer Patients Sridhar, Sriram; Paz-Ares, Luis; Liu, Hao; Shen, Kui; Morehouse, Chris; Rizvi, Naiyer; Segal, Neil H.; Jin, Xiaoping; Zheng, Yanan; Narwal, Rajesh; Gupta, Ashok; Dennis, Phillip A.; Ye, Jiabu; Mukhopadhyay, Pralay; Higgs, Brandon W.; Ranade, Koustubh CLINICAL LUNG CANCER 1525-7304 (2019) DOI / 10.1016/j.cllc.2019.06.020 Gold other
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Article Analysis of mismatch repair (MMR) proteins expression in a series of malignant pleural mesothelioma (MPM) patients Cedres, S.; Ponce-Aix, S.; Iranzo, P.; Callejo, A.; Pardo, N.; Navarro, A.; Martinez-Marti, A.; Gomez-Abecia, S.; Zucchiatti, A. C.; Enguita, A. B.; Miquel, J. M.; Viaplana, C.; Dienstmann, R.; Paz-Ares, L.; Felip, E. CLINICAL & TRANSLATIONAL ONCOLOGY 1699-048X (2020) DOI / 10.1007/s12094-019-02275-9
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Article FGFR4 increases EGFR oncogenic signaling in lung adenocarcinoma, and their combined inhibition is highly effective Quintanal-Villalonga, Alvaro; Molina-Pinelo, Sonia; Yague, Patricia; Marrugal, Angela; Ojeda-Marquez, Laura; Suarez, Rocio; Ponce-Aix, Santiago; Belen Enguita, Ana; Carnero, Amancio; Ferrer, Irene; Paz-Ares, Luis LUNG CANCER 0169-5002 (2019) DOI / 10.1016/j.lungcan.2019.02.007
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Article A Randomized Phase III Study of Abemaciclib Versus Erlotinib in Patients with Stage IV Non-small Cell Lung Cancer With a Detectable KRAS Mutation Who Failed Prior Platinum-Based Therapy: JUNIPER Goldman, Jonathan W.; Mazieres, Julien; Barlesi, Fabrice; Dragnev, Konstantin H.; Koczywas, Marianna; Goskel, Tuncay; Cortot, Alexis B.; Girard, Nicolas; Wesseler, Claas; Bischoff, Helge; Nadal, Ernest; Park, Keunchil; Lu, Shun; Taus, Alvaro; Cobo, Manuel; FRONTIERS IN ONCOLOGY 2234-943X (2020) DOI / 10.3389/fonc.2020.578756 Gold DOAJ, Green published
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Article Outcomes With Pembrolizumab Plus Platinum-Based Chemotherapy for Patients With NSCLC and Stable Brain Metastases: Pooled Analysis of KEYNOTE-021,-189, and-407 Powell, Steven F.; Rodriguez-Abreu, Delvys; Langer, Corey J.; Tafreshi, Ali; Paz-Ares, Luis; Kopp, Hans-Georg; Rodriguez-Cid, Jeronimo; Kowalski, Dariusz M.; Cheng, Ying; Kurata, Takayasu; Awad, Mark M.; Lin, Jinaxin; Zhao, Bin; Pietanza, M. Catherine; Pip JOURNAL OF THORACIC ONCOLOGY 1556-0864 (2021) DOI / 10.1016/j.jtho.2021.06.020 Hybrid
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Article Treatment outcomes by histology in REVEL: A randomized phase III trial of Ramucirumab plus docetaxel for advanced non-small cell lung cancer Paz-Ares, Luis G.; Perol, Maurice; Ciuleanu, Tudor-Eliade; Kowalyszyn, Ruben Dario; Reck, Martin; Lewanski, Conrad R.; Syrigos, Konstantinos; Arrieta, Oscar; Prabhash, Kumar; Park, Keunchil; Pikiel, Joanna; Goksel, Tuncay; Lee, Pablo; Zimmermann, Anna; Car LUNG CANCER 0169-5002 (2017) DOI / 10.1016/j.lungcan.2017.05.021
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Article Afatinib as First-line Treatment of Older Patients With EGFR Mutation-Positive Non-Small-Cell Lung Cancer: Subgroup Analyses of the LUX-Lung 3, LUX-Lung 6, and LUX-Lung 7 Trials Wu, Yi-Long; Sequist, Lecia V.; Tan, Eng-Huat; Geater, Sarayut L.; Orlov, Sergey; Zhang, LI; Lee, Ki Hyeong; Tsai, Chun-Ming; Kato, Terufumi; Barrios, Carlos H.; Schuler, Martin; Hirsh, Vera; Yamamoto, Nobuyuki; O'Byrne, Kenneth; Boyer, Michael; Mok, Tony; CLINICAL LUNG CANCER 1525-7304 (2018) DOI / 10.1016/j.cllc.2018.03.009 Green published, Gold other
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Article Randomised phase 2 study of pembrolizumab plus CC-486 versus pembrolizumab plus placebo in patients with previously treated advanced non-small cell lung cancer Levy, Benjamin P.; Giaccone, Giuseppe; Besse, Benjamin; Felip, Enriqueta; Garassino, Marina Chiara; Domine Gomez, Manuel; Garrido, Pilar; Piperdi, Bilal; Ponce-Aix, Santiago; Menezes, Daniel; MacBeth, Kyle J.; Risueno, Alberto; Slepetis, Ruta; Wu, Xiaoling EUROPEAN JOURNAL OF CANCER 0959-8049 (2019) DOI / 10.1016/j.ejca.2018.11.028
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Article First-line durvalumab plus platinum-etoposide in extensive-stage small-cell lung cancer: CASPIAN Japan subgroup analysis Hotta, Katsuyuki; Nishio, Makoto; Saito, Haruhiro; Okamoto, Isamu; Nakahara, Yasuharu; Hayashi, Hidetoshi; Hayama, Manabu; Laud, Peter; Jiang, Haiyi; Paz-Ares, Luis; Azuma, Koichi INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY 1341-9625 (2021) DOI / 10.1007/s10147-021-01899-8 Gold other
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Article Venous thromboembolism with EGFR monoclonal antibody necitumumab in stage IV non-small cell lung cancer: A retrospective cohort analysis Young, Kelvin; Paz-Ares, Luis; Thatcher, Nick; Spigel, David R.; Shahidi, Javad; Soldatenkova, Victoria; Grau, Gerrit; Kurek, Raffael; Shepherd, Frances A. THROMBOSIS RESEARCH 0049-3848 (2018) DOI / 10.1016/j.thromres.2018.05.004
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Article Meta-analysis examining impact of age on overall survival with pemetrexed for the treatment of advanced non-squamous non-small cell lung cancer Paz-Ares, Luis G.; Zimmermann, Annamaria; Ciuleanu, Tudor; Bunn, Paul A.; Antonio, Belen San; Denne, Jonathan; Iturria, Nancy; John, William; Scagliotti, Giorgio V. LUNG CANCER 0169-5002 (2017) DOI / 10.1016/j.lungcan.2016.12.007
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Review Mechanisms of acquired resistance to first- and second-generation EGFR tyrosine kinase inhibitors Westover, D.; Zugazagoitia, J.; Cho, B. C.; Lovly, C. M.; Paz-Ares, L. ANNALS OF ONCOLOGY 0923-7534 (2018) DOI / 10.1093/annonc/mdx703 Green published, Bronze
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Article Efficacy and Safety of Necitumumab Continuation Therapy in the Phase III SQUIRE Study of Patients With Stage IV Squamous Non-Small-Cell Lung Cancer Ciuleanu, Tudor; Socinski, Mark A.; Obasaju, Coleman; Luft, Alexander V.; Szczesna, Aleksandra; Szafranski, Wojciech; Ramlau, Rodryg; Balint, Beatrix; Molinier, Olivier; Depenbrock, Henrik; Nanda, Shivani; Paz-Ares, Luis; Thatcher, Nick CLINICAL LUNG CANCER 1525-7304 (2018) DOI / 10.1016/j.cllc.2017.10.004
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Article Treatment options beyond immunotherapy in patients with wild-type lung adenocarcinoma: a Delphi consensus Isla, D.; De Castro, J.; Garcia-Campelo, R.; Lianes, P.; Felip, E.; Garrido, P.; Paz-Ares, L.; Trigo, J. M. CLINICAL & TRANSLATIONAL ONCOLOGY 1699-048X (2020) DOI / 10.1007/s12094-019-02191-y Gold other
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Article Safety of eribulin as third-line chemotherapy in HER2-negative, advanced breast cancer pre-treated with taxanes and anthracycline: OnSITE study Manso, Luis; Moreno Anton, Fernando; Izarzugaza Peron, Yann; Delgado Mingorance, Juan, I; Borrega Garcia, Pablo; Echarri Gonzalez, Maria J.; Martinez-Janez, Noelia; Lopez-Gonzalez, Ana; Olier Garate, Clara; Ballesteros Garcia, Anabel; Chacon Lopez-Muniz, I BREAST JOURNAL 1075-122X (2019) DOI / 10.1111/tbj.13199
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Article Incidence of venous thromboembolism in patients with non-hematological cancer admitted for COVID-19 at a third-level hospital in Madrid Paredes-Ruiz, Diana; Gomez-Cuervo, Covadonga; Gomez-Martin, Carlos; Sanchez-Guerrero, Angel; Gonzalez-Olmedo, Jesus; Lopez-Lopez, Flora; Bover-Larroya, Mateo; Yarza-Barrio, Ramon; Jara-Casas, Diego Dimas; Castelo-Laureiro, Alicia; Revilla-Ostolaza, Yolanda JOURNAL OF THROMBOSIS AND THROMBOLYSIS 0929-5305 (2021) DOI / 10.1007/s11239-021-02448-w Bronze, Green published
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Editorial Material Afatinib With Pembrolizumab for Treatment of Patients With Locally Advanced/Metastatic Squamous Cell Carcinoma of the Lung: The LUX-Lung IO/KEYNOTE 497 Study Protocol Levy, Benjamin; Paz-Ares, Luis; Bennouna, Jaafar; Felip, Enriqueta; Rodriguez Abreu, Delvys; Isla, Dolores; Barlesi, Fabrice; Molinier, Olivier; Madelaine, Jeannick; Audigier-Valette, Clarisse; Kim, Sang-We; Kim, Hye Ryun; Ozguroglu, Mustafa; Erman, Mustaf CLINICAL LUNG CANCER 1525-7304 (2019) DOI / 10.1016/j.cllc.2018.12.022 Gold other
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Article The Roles of ImprintedSLC22A18andSLC22A18ASGene Overexpression Caused by Promoter CpG Island Hypomethylation as Diagnostic and Prognostic Biomarkers for Non-Small Cell Lung Cancer Patients Noguera-Ucles, Jose Francisco; Boyero, Laura; Salinas, Ana; Cordero Varela, Juan Antonio; Benedetti, Johana Cristina; Bernabe-Caro, Reyes; Sanchez-Gastaldo, Amparo; Alonso, Miriam; Paz-Ares, Luis; Molina-Pinelo, Sonia CANCERS (2020) DOI / 10.3390/cancers12082075 Gold DOAJ, Green published

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