Molecular Biology & Genetics


  Listando 17 trabajos del autor/autora 38
Lista de trabajos en el área Molecular Biology & Genetics
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Article Complete Regression of Advanced Pancreatic Ductal Adenocarcinomas upon Combined Inhibition of EGFR and C-RAF Teresa Blasco, Maria; Navas, Carolina; Martin-Serrano, Guillermo; Grana-Castro, Osvaldo; Lechuga, Carmen G.; Martin-Diaz, Laura; Djurec, Magdolna; Li, Jing; Morales-Cacho, Lucia; Esteban-Burgos, Laura; Perales-Paton, Javier; Bousquet-Mur, Emilie; Castellan CANCER CELL 1535-6108 (2019) DOI / 10.1016/j.ccell.2019.03.002 Green accepted, Bronze
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Article A Braf kinase-inactive mutant induces lung adenocarcinoma Nieto, Patricia; Ambrogio, Chiara; Esteban-Burgos, Laura; Gomez-Lopez, Gonzalo; Teresa Blasco, Maria; Yao, Zhan; Marais, Richard; Rosen, Neal; Chiarle, Roberto; Pisano, David G.; Barbacid, Mariano; Santamaria, David NATURE 0028-0836 (2017) DOI / 10.1038/nature23297 Green accepted
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Article c-RAF Ablation Induces Regression of Advanced Kras/Trp53 Mutant Lung Adenocarcinomas by a Mechanism Independent of MAPK Signaling Sanclemente, Manuel; Francoz, Sarah; Esteban-Burgos, Laura; Bousquet-Mur, Emilie; Djurec, Magdolna; Lopez-Casas, Pedro P.; Hidalgo, Manuel; Guerra, Carmen; Drosten, Matthias; Musteanu, Monica; Barbacid, Mariano CANCER CELL 1535-6108 (2018) DOI / 10.1016/j.ccell.2017.12.014 Bronze
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Article Inactivation of Capicua in adult mice causes T-cell lymphoblastic lymphoma Simon-Carrasco, Lucia; Grana, Osvaldo; Salmon, Marina; Jacob, Harrys K. C.; Gutierrez, Alejandro; Jimenez, Gerardo; Drosten, Matthias; Barbacid, Mariano GENES & DEVELOPMENT 0890-9369 (2017) DOI / 10.1101/gad.300244.117 Gold, Green published
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Article KRAS4A induces metastatic lung adenocarcinomas in vivo in the absence of the KRAS4B isoform Salmon, Marina; Paniagua, Guillem; Lechuga, Carmen G.; Fernandez-Garcia, Fernando; Zarzuela, Eduardo; Alvarez-Diaz, Ruth; Musteanu, Monica; Guerra, Carmen; Caleiras, Eduardo; Munoz, Javier; Ortega, Sagrario; Drosten, Matthias; Barbacid, Mariano PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 0027-8424 (2021) DOI / 10.1073/pnas.2023112118
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Article ERF deletion rescues RAS deficiency in mouse embryonic stem cells Mayor-Ruiz, Cristina; Olbrich, Teresa; Drosten, Matthias; Lecona, Emilio; Vega-Sendino, Maria; Ortega, Sagrario; Dominguez, Orlando; Barbacid, Mariano; Ruiz, Sergio; Fernandez-Capetillo, Oscar GENES & DEVELOPMENT 0890-9369 (2018) DOI / 10.1101/gad.310086.117 Green published, Gold other
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Article Requirement for epithelial p38 alpha in KRAS-driven lung tumor progression Vitos-Faleato, Jessica; Real, Sebastian M.; Gutierrez-Prat, Nuria; Villanueva, Alberto; Llonch, Elisabet; Drosten, Matthias; Barbacid, Mariano; Nebreda, Angel R. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 0027-8424 (2020) DOI / 10.1073/pnas.1921404117 Green accepted, Green published, Bronze
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Article Afatinib restrains K-RAS-driven lung tumorigenesis Moll, Herwig P.; Pranz, Klemens; Musteanu, Monica; Grabner, Beatrice; Hruschka, Natascha; Mohrherr, Julian; Aigner, Petra; Stiedl, Patricia; Brcic, Luka; Laszlo, Viktoria; Schramek, Daniel; Moriggl, Richard; Eferl, Robert; Moldvay, Judit; Derso, Katalin; L SCIENCE TRANSLATIONAL MEDICINE 1946-6234 (2018) DOI / 10.1126/scitranslmed.aao2301 Bronze
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Article A new mode of DNA binding distinguishes Capicua from other HMG-box factors and explains its mutation patterns in cancer Fores, Marta; Simon-Carrasco, Lucia; Ajuria, Leiore; Samper, Nurla; Gonzalez-Crespo, Sergio; Drosten, Matthias; Barbacid, Mariano; Jimenez, Gerardo PLOS GENETICS 1553-7390 (2017) DOI / 10.1371/journal.pgen.1006622 Green published, Green submitted, Gold
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Letter RAF1 kinase activity is dispensable for KRAS/p53 mutant lung tumor progression Sanclemente, Manuel; Nieto, Patricia; Garcia-Alonso, Sara; Fernandez-Garcia, Fernando; Esteban-Burgos, Laura; Guerra, Carmen; Drosten, Matthias; Caleiras, Eduardo; Martinez-Torrecuadrada, Jorge; Santamaria, David; Musteanu, Monica; Barbacid, Mariano CANCER CELL 1535-6108 (2021) DOI / 10.1016/j.ccell.2021.01.008
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Article RAF inhibitor PLX8394 selectively disrupts BRAF dimers and RAS-independent BRAF-mutant-driven signaling Yao, Zhan; Gao, Yijun; Su, Wenjing; Yaeger, Rona; Tao, Jessica; Na, Na; Zhang, Ying; Zhang, Chao; Rymar, Andrey; Tao, Anthony; Timaul, Neilawattie M.; Mcgriskin, Rory; Outmezguine, Nathaniel A.; Zhao, HuiYong; Chang, Qing; Qeriqi, Besnik; Barbacid, Mariano NATURE MEDICINE 1078-8956 (2019) DOI / 10.1038/s41591-018-0274-5 Green accepted
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Review Targeting the MAPK Pathway in KRAS-Driven Tumors Drosten, Matthias; Barbacid, Mariano CANCER CELL 1535-6108 (2020) DOI / 10.1016/j.ccell.2020.03.013
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Article In vivo oncogenic conflict triggered by co-existing KRAS and EGFR activating mutations in lung adenocarcinoma Ambrogio, C.; Barbacid, M.; Santamaria, D. ONCOGENE 0950-9232 (2017) DOI / 10.1038/onc.2016.385
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Article Cyclin-Dependent Kinase 4 Regulates Adult Neural Stem Cell Proliferation and Differentiation in Response to Insulin Chirivella, Laura; Kirstein, Martina; Ferron, Sacri R.; Domingo-Muelas, Ana; Durupt, Fabrice C.; Acosta-Umanzor, Carlos; Cano-Jaimez, Marife; Perez-Sanchez, Francisco; Barbacid, Mariano; Ortega, Sagrario; Burks, Deborah J.; Farinas, Isabel STEM CELLS 1066-5099 (2017) DOI / 10.1002/stem.2694 Bronze
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Review The Capicua tumor suppressor: a gatekeeper of Ras signaling in development and cancer Simon-Carrasco, Lucia; Jimenez, Gerardo; Barbacid, Mariano; Drosten, Matthias CELL CYCLE 1538-4101 (2018) DOI / 10.1080/15384101.2018.1450029 Green published, Green submitted, Bronze
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Article Cyclin E1 and cyclin-dependent kinase 2 are critical for initiation, but not for progression of hepatocellular carcinoma Sonntag, Roland; Giebeler, Nives; Nevzorova, Yulia A.; Bangen, Joerg-Martin; Fahrenkamp, Dirk; Lambertz, Daniela; Haas, Ute; Hu, Wei; Gassier, Nikolaus; Cubero, Francisco Javier; Mueller-Newen, Gerhard; Abdallan, Ali T.; Weiskirchen, Ralf; Ticconi, Fabio; PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 0027-8424 (2018) DOI / 10.1073/pnas.1807155115 Bronze, Green published
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Article Myc stimulates cell cycle progression through the activation of Cdk1 and phosphorylation of p27 Garcia-Gutierrez, Lucia; Bretones, Gabriel; Molina, Ester; Arechaga, Ignacio; Symonds, Catherine; Acosta, Juan C.; Blanco, Rosa; Fernandez, Adrian; Alonso, Leticia; Sicinski, Piotr; Barbacid, Mariano; Santamaria, David; Leon, Javier SCIENTIFIC REPORTS 2045-2322 (2019) DOI / 10.1038/s41598-019-54917-1 Gold DOAJ, Green published

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