Clinical Medicine

Listando 47 trabajos del autor/autora 38

Lista de trabajos en el área Clinical Medicine

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Article Safeguarding the future of independent, academic clinical cancer research in Europe for the benefit of patients Negrouk, Anastassia; Lacombe, Denis; Cardoso, Fatima; Morin, Franck; Carrasco, Eva; Maurel, Joan; Maibach, Rudolf; Aranda, Enrique; Marais, Richard; Stahel, Rolf A. ESMO OPEN (2017) DOI / 10.1136/esmoopen-2017-000187 Gold DOAJ, Green accepted, Green published

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Review Incorporating BEAMing technology as a liquid biopsy into clinical practice for the management of colorectal cancer patients: an expert taskforce review Garcia-Foncillas, J.; Alba, E.; Aranda, E.; Diaz-Rubio, E.; Lopez-Lopez, R.; Tabernero, J.; Vivancos, A. ANNALS OF ONCOLOGY 0923-7534 (2017) DOI / 10.1093/annonc/mdx501 Gold other, Green published

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Article Concordance of blood- and tumor-based detection of RAS mutations to guide anti-EGFR therapy in metastatic colorectal cancer Grasselli, J.; Elez, E.; Caratu, G.; Matito, J.; Santos, C.; Macarulla, T.; Vidal, J.; Garcia, M.; Vieitez, J. M.; Paez, D.; Falco, E.; Lopez Lopez, C.; Aranda, E.; Jones, F.; Sikri, V.; Nuciforo, P.; Fasani, R.; Tabernero, J.; Montagut, C.; Azuara, D.; Di ANNALS OF ONCOLOGY 0923-7534 (2017) DOI / 10.1093/annonc/mdx112 Green published, Hybrid

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Article Circulating Cell-Free DNA-Based Liquid Biopsy Markers for the Non-Invasive Prognosis and Monitoring of Metastatic Pancreatic Cancer Toledano-Fonseca, Marta; Teresa Cano, M.; Inga, Elizabeth; Rodriguez-Alonso, Rosa; Auxiliadora Gomez-Espana, M.; Guil-Luna, Silvia; Mena-Osuna, Rafael; de la Haba-Rodriguez, Juan R.; Rodriguez-Ariza, Antonio; Aranda, Enrique CANCERS (2020) DOI / 10.3390/cancers12071754 Green published, Gold other

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Article HIPECT4: multicentre, randomized clinical trial to evaluate safety and efficacy of Hyperthermic intra-peritoneal chemotherapy (HIPEC) with Mitomycin C used during surgery for treatment of locally advanced colorectal carcinoma Arjona-Sanchez, A.; Barrios, P.; Boldo-Roda, E.; Camps, B.; Carrasco-Campos, J.; Concepcion Martin, V.; Garcia-Fadrique, A.; Gutierrez-Calvo, A.; Morales, R.; Ortega-Perez, G.; Perez-Viejo, E.; Prada-Villaverde, A.; Torres-Melero, J.; Vicente, E.; Villarej BMC CANCER (2018) DOI / 10.1186/s12885-018-4096-0 Gold DOAJ, Green published

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Article Exhaled breath condensate biomarkers for the early diagnosis of lung cancer using proteomics Lopez-Sanchez, Laura M.; Jurado-Gamez, Bernabe; Feu-Collado, Nuria; Valverde, Araceli; Canas, Amanda; Fernandez-Rueda, Jose L.; Aranda, Enrique; Rodriguez-Ariza, Antonio AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY 1040-0605 (2017) DOI / 10.1152/ajplung.00119.2017 Bronze

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Article Comparison of the Clinical Sensitivity of the Idylla Platform and the OncoBEAM RAS CRC Assay for KRAS Mutation Detection in Liquid Biopsy Samples Vivancos, Ana; Aranda, Enrique; Benavides, Manuel; Elez, Elena; Auxiliadora Gomez-Espana, Maria; Toledano, Marta; Alvarez, Martina; Chica Parrado, Maria Rosario; Garcia-Barberan, Vanesa; Diaz-Rubio, Eduardo SCIENTIFIC REPORTS 2045-2322 (2019) DOI / 10.1038/s41598-019-45616-y Gold DOAJ, Green published

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Article Improving selection of patients with metastatic colorectal cancer to benefit from cetuximab based on KIR genotypes Manzanares-Martin, Barbara; Cebrian Aranda, Arancha; del Puerto-Nevado, Laura; Gonzalez, Rafael; Solanes, Sonia; Auxiliadora Gomez-Espana, Maria; Garcia-Foncillas, Jesus; Aranda, Enrique JOURNAL FOR IMMUNOTHERAPY OF CANCER (2021) DOI / 10.1136/jitc-2020-001705 Gold DOAJ, Green published

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Article Perioperative trastuzumab, capecitabine and oxaliplatin in patients with HER2-positive resectable gastric or gastro-oesophageal junction adenocarcinoma: NEOHX phase II trial Rivera, Fernando; Izquierdo-Manuel, Marta; Garcia-Alfonso, Pilar; de Castro, Eva Martinez; Gallego, Javier; Limon, Maria Luisa; Alsina, Maria; Lopez, Luis; Galan, Maica; Falco, Esther; Manzano, Jose Luis; Gonzalez, Encarna; Munoz-Unceta, Nerea; Lopez, Carl EUROPEAN JOURNAL OF CANCER 0959-8049 (2021) DOI / 10.1016/j.ejca.2020.12.005

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Article Prospective multicenter real-world RAS mutation comparison between OncoBEAM-based liquid biopsy and tissue analysis in metastatic colorectal cancer Garcia-Foncillas, Jesus; Tabernero, Josep; Elez, Elena; Aranda, Enrique; Benavides, Manuel; Camps, Carlos; Jantus-Lewintre, Eloisa; Lopez, Rafael; Muinelo-Romay, Laura; Montagut, Clara; Anton, Antonio; Lopez, Guillermo; Diaz-Rubio, Eduardo; Rojo, Federico; BRITISH JOURNAL OF CANCER 0007-0920 (2018) DOI / 10.1038/s41416-018-0293-5 Green published, Gold other, Green accepted

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Article Phase II study of high-sensitivity genotyping of KRAS, NRAS, BRAF and PIK3CA to ultra-select metastatic colorectal cancer patients for panitumumab plus FOLFIRI: the ULTRA trial Santos, C.; Azuara, D.; Vieitez, J. M.; Paez, D.; Falco, E.; Elez, E.; Lopez-Lopez, C.; Valladares, M.; Robles-Diaz, L.; Garcia-Alfonso, P.; Buges, C.; Duran, G.; Salud, A.; Navarro, V.; Capella, G.; Aranda, E.; Salazar, R.; Ruiz de Mena, I.; Rodriguez, S. ANNALS OF ONCOLOGY 0923-7534 (2019) DOI / 10.1093/annonc/mdz082 Gold other

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Article Association of Bevacizumab Plus Oxaliplatin-Based Chemotherapy With Disease-Free Survival and Overall Survival in Patients With Stage II Colon Cancer A Secondary Analysis of the AVANT Trial Chibaudel, Benoist; Henriques, Julie; Rakez, Manel; Brenner, Baruch; Kim, Tae Won; Martinez-Villacampa, Mercedes; Gallego-Plazas, Javier; Cervantes, Andres; Shim, Katharine; Jonker, Derek; Guerin-Meyer, Veronique; Mineur, Laurent; Banzi, Chiara; Dewdney, A JAMA NETWORK OPEN 2574-3805 (2020) DOI / 10.1001/jamanetworkopen.2020.20425 Gold DOAJ, Green published

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Article Clinical Utility of microRNAs in Exhaled Breath Condensate as Biomarkers for Lung Cancer Perez-Sanchez, Carlos; Barbarroja, Nuria; Pantaleao, Lucas C.; Lopez-Sanchez, Laura M.; Ozanne, Susan E.; Jurado-Gamez, Bernabe; Aranda, Enrique; Lopez-Pedrera, Chary; Rodriguez-Ariza, Antonio JOURNAL OF PERSONALIZED MEDICINE (2021) DOI / 10.3390/jpm11020111 Green published, Gold

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Article Early Clinical Experience with Trifluridine/Tipiracil for Refractory Metastatic Colorectal Cancer: The ROS Study Garcia-Alfonso, Pilar; Munoz, Andres; Jimenez-Castro, Jeronimo; Jimenez-Fonseca, Paula; Pericay, Carles; Longo-Munoz, Federico; Reyna-Fortes, Carmen; Argiles-Martinez, Guillem; Gonzalez-Astorga, Beatriz; Jose Gomez-Reina, Maria; Ruiz-Casado, Ana; Rodriguez CANCERS (2021) DOI / 10.3390/cancers13184514 Green published, Gold

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Article Recommendations for SIR-Spheres Y-90 resin microspheres in chemotherapy-refractory/intolerant colorectal liver metastases Aranda, Enrique; Aparicio, Jorge; Ignacio Bilbao, Jose; Garcia Alfonso, Pilar; Maurel, Joan; Rodriguez, Javier; Sangro, Bruno; Maria Vieitez, Jose; Feliu, Jaime FUTURE ONCOLOGY 1479-6694 (2017) DOI / 10.2217/fon-2017-0220

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Article First-line mFOLFOX plus cetuximab followed by mFOLFOX plus cetuximab or single-agent cetuximab as maintenance therapy in patients with metastatic colorectal cancer: Phase II randomised MACRO2 TTD study Aranda, E.; Garcia-Alfonso, P.; Benavides, M.; Sanchez Ruiz, A.; Guillen-Ponce, C.; Safont, M. J.; Alcaide, J.; Gomez, A.; Lopez, R.; Manzano, J. L.; Mendez Urena, M.; Sastre, J.; Rivera, F.; Gravalos, C.; Garcia, T.; Martin-Valades, J. I.; Falco, E.; Nava EUROPEAN JOURNAL OF CANCER 0959-8049 (2018) DOI / 10.1016/j.ejca.2018.06.024

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Article Tumour location and efficacy of first-line EGFR inhibitors in KRAS/RAS wild-type metastatic colorectal cancer: retrospective analyses of two phase II randomised Spanish TTD trials Benavides, Manuel; Diaz-Rubio, Eduardo; Carrato, Alfredo; Abad, Albert; Guillen, Carmen; Garcia-Alfonso, Pilar; Gil, Silvia; Cano, Maria Teresa; Safont, Maria Jose; Gravalos, Cristina; Manzano, Jose Luis; Sanchez, Antonio; Alcaide, Julia; Lopez, Rafael; Ma ESMO OPEN (2019) DOI / 10.1136/esmoopen-2019-000599 Gold DOAJ

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Article Implementation of the Quality Oncology Practice Initiative Program in Spain: First Results and Implications Camps, Carlos; Lopez, Rafael; Anton, Antonio; Aranda, Enrique; Carrato, Alfredo; Cruz, Juan Jesus; Jacobo Cunquero-Tomas, Alberto; Diaz-Rubio, Eduardo; Feyjoo, Margarita; Garcia-Foncillas, Jesus; Gascon, Pere; Lugo, Ilse; Rogado, Alvaro; Guillem, Vicente JCO ONCOLOGY PRACTICE 2688-1527 (2021) DOI / 10.1200/op.20.00683

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Article FOLFOXIRI plus bevacizumab versus FOLFOX plus bevacizumab for patients with metastatic colorectal cancer and >= 3 circulating tumour cells: the randomised phase III VISNu-1 trial Aranda, Enrique; Maria Vieitez, Jose; Gomez-Espana, Auxiliadora; Gil Calle, Silvia; Salud-Salvia, Antonieta; Grana, Begona; Garcia-Alfonso, Pilar; Rivera, Fernando; Alfonso Quintero-Aldana, Guillermo; Jose Reina-Zoilo, Juan; Gonzalez-Flores, Encarnacion; S ESMO OPEN (2020) DOI / 10.1136/esmoopen-2020-000944 Gold DOAJ, Green published

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Article Gemcitabine-erlotinib versus gemcitabine-erlotinib-capecitabine in the first-line treatment of patients with metastatic pancreatic cancer: Efficacy and safety results of a phase IIb randomised study from the Spanish TTD Collaborative Group Irigoyen, Antonio; Gallego, Javier; Guillen Ponce, Carmen; Vera, Ruth; Iranzo, Vega; Ales, Inmaculada; Arevalo, Sara; Pisa, Aleydis; Martin, Marta; Salud, Antonieta; Falco, Esther; Saenz, Alberto; Manzano Mozo, Jose Luis; Pulido, Gema; Martinez Galan, Joaq EUROPEAN JOURNAL OF CANCER 0959-8049 (2017) DOI / 10.1016/j.ejca.2016.12.032

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Review Clinical and Regulatory Considerations for the Use of Bevacizumab Biosimilars in Metastatic Colorectal Cancer Taieb, Julien; Aranda, Enrique; Raouf, Sherif; Dunn, Helen; Arnold, Dirk CLINICAL COLORECTAL CANCER 1533-0028 (2021) DOI / 10.1016/j.clcc.2020.10.005 Gold other

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Article Nitric oxide-targeted therapy inhibits stemness and increases the efficacy of tamoxifen in estrogen receptor-positive breast cancer cells Lopez-Sanchez, Laura M.; Mena, Rafael; Guil-Luna, Silvia; Mantrana, Ana; Penarando, Jon; Toledano-Fonseca, Marta; Conde, Francisco; de la Haba-Rodriguez, Juan R.; Aranda, Enrique; Rodriguez-Ariza, Antonio LABORATORY INVESTIGATION 0023-6837 (2020) DOI / 10.1038/s41374-020-00507-z

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Article Single-Agent Regorafenib in Metastatic Colorectal Cancer Patients with Any RAS or BRAF Mutation Previously Treated with FOLFOXIRI plus Bevacizumab (PREVIUM Trial) Garcia-Alfonso, Pilar; Benavides, Manuel; Falco, Esther; Munoz, Andres; Gomez, Auxiliadora; Sastre, Javier; Rivera, Fernando; Montagut, Clara; Salgado, Mercedes; Lopez-Ladron, Amelia; Lopez, Rafael; Ruiz de Mena, Inmaculada; Duran, Gema; Aranda, Enrique ONCOLOGIST 1083-7159 (2018) DOI / 10.1634/theoncologist.2018-0316 Green published, Bronze

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Article SWATH-based proteomics reveals processes associated with immune evasion and metastasis in poor prognosis colorectal tumours Lopez-Sanchez, Laura M.; Jimenez-Izquierdo, Rafael; Penarando, Jon; Mena, Rafael; Guil-Luna, Silvia; Toledano, Marta; Conde, Francisco; Villar, Carlos; Diaz, Cesar; Ortea, Ignacio; de la Haba-Rodriguez, Juan R.; Aranda, Enrique; Rodriguez-Ariza, Antonio JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 1582-1838 (2019) DOI / 10.1111/jcmm.14693 Gold DOAJ, Green published

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Article The Combination of Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio with Liquid Biopsy Biomarkers Improves Prognosis Prediction in Metastatic Pancreatic Cancer Toledano-Fonseca, Marta; Cano, M. Teresa; Inga, Elizabeth; Gomez-Espana, Auxiliadora; Guil-Luna, Silvia; Garcia-Ortiz, Maria Victoria; Mena-Osuna, Rafael; de la Haba-Rodriguez, Juan R.; Rodriguez-Ariza, Antonio; Aranda, Enrique CANCERS (2021) DOI / 10.3390/cancers13061210 Gold DOAJ, Green published

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Article First-Line Biological Agents Plus Chemotherapy in Older Patients with Metastatic Colorectal Cancer: A Retrospective Pooled Analysis Garcia-Alfonso, Pilar; Diaz-Rubio, Eduardo; Abad, Albert; Carrato, Alfredo; Massuti, Bartomeu; Ortiz-Morales, Maria Jose; Manzano Mozo, Jose Luis; Munoz, Andres; Duran, Gema; Sastre, Javier; Safont, Maria Jose; Ferreiro, Reyes; Rivera, Fernando; Gonzalez, DRUGS & AGING 1170-229X (2021) DOI / 10.1007/s40266-021-00834-w Gold other, Green published

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Article Prognostic value of primary tumour resection in synchronous metastatic colorectal cancer: Individual patient data analysis of first-line randomised trials from the ARCAD database van Rooijen, K. L.; Shi, Q.; Goey, K. K. H.; Meyers, J.; Heinemann, V.; Diaz-Rubio, E.; Aranda, E.; Falcone, A.; Green, E.; de Gramont, A.; Sargent, D. J.; Punt, C. J. A.; Koopman, M. EUROPEAN JOURNAL OF CANCER 0959-8049 (2018) DOI / 10.1016/j.ejca.2017.12.014

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Article Study of the Spanish Society of Medical Oncology (SEOM) on the access to oncology drugs and predictive biomarkers in Spain Rodriguez-Lescure, A.; de la Pena, F. A.; Aranda, E.; Calvo, A.; Felip, E.; Garrido, P.; Vera, R. CLINICAL & TRANSLATIONAL ONCOLOGY 1699-048X (2020) DOI / 10.1007/s12094-020-02366-y Gold other, Green published

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Article Association of Tumor Budding With Immune Evasion Pathways in Primary Colorectal Cancer and Patient-Derived Xenografts Guil-Luna, Silvia; Mena, Rafael; Navarrete-Sirvent, Carmen; Maria Lopez-Sanchez, Laura; Khouadri, Karima; Toledano-Fonseca, Marta; Mantrana, Ana; Guler, Ipek; Villar, Carlos; Diaz, Cesar; Javier Medina-Fernandez, Francisco; Rafael De la Haba-Rodriguez, Jua FRONTIERS IN MEDICINE (2020) DOI / 10.3389/fmed.2020.00264 Gold DOAJ, Green published

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Article Genotype-based selection of treatment of patients with advanced colorectal cancer (SETICC): a pharmacogenetic-based randomized phase II trial Abad, A.; Martinez-Balibrea, E.; Ma Vieitez, J.; Alonso-Orduna, V.; Garcia Alfonso, P.; Manzano, J. L.; Massuti, B.; Benavides, M.; Carrato, A.; Zanui, M.; Gallego, J.; Gravalos, C.; Conde, V.; Provencio, M.; Valladares-Ayerbes, M.; Salazar, R.; Sastre, J. ANNALS OF ONCOLOGY 0923-7534 (2018) DOI / 10.1093/annonc/mdx737 Bronze

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Article Ultra-selection of metastatic colorectal cancer patients using next-generation sequencing to improve clinical efficacy of anti-EGFR therapy Vidal, J.; Bellosillo, B.; Santos Vivas, C.; Garcia-Alfonso, P.; Carrato, A.; Cano, M. T.; Garcia-Carbonero, R.; Elez, E.; Losa, F.; Massuti, B.; Valladares-Ayerbes, M.; Vieitez, J. M.; Manzano, J. L.; Azuara, D.; Gallego, J.; Pairet, S.; Capella, G.; Sala ANNALS OF ONCOLOGY 0923-7534 (2019) DOI / 10.1093/annonc/mdz005 Gold other

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Article A phase 2 study of panitumumab with irinotecan as salvage therapy in chemorefractory KRAS exon 2 wild-type metastatic colorectal cancer patients Elez, Elena; Pericay, Caries; Valladares-Ayerbes, Manuel; Bando, Inmaculada; Safont, Maria Jose; Gallego, Javier; Gravalos, Cristina; Arrivi, Antonio; Carrato, Alfredo; Conde, Veronica; Jose Ortiz, Maria; Lopez, Carlos; Alonso, Beatriz; Ruiz de Mena, Inmac BRITISH JOURNAL OF CANCER 0007-0920 (2019) DOI / 10.1038/s41416-019-0537-z Gold other, Green published

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Article Influence of BRAF and PIK3CA mutations on the efficacy of FOLFIRI plus bevacizumab or cetuximab as first-line therapy in patients with RAS wild-type metastatic colorectal carcinoma and < 3 baseline circulating tumour cells: the randomised phase II VISNU-2 Sastre, J.; Garcia-Alfonso, P.; Vieitez, J. M.; Cano, M. T.; Rivera, F.; Reina-Zoilo, J. J.; Salud-Salvia, A.; Quintero, G.; Robles-Diaz, L.; Safont, M. J.; La Casta, A.; Gil, S.; Polo, E.; Asensio-Martinez, E.; Garcia-Paredes, B.; Lopez, R. L.; Guillot, M ESMO OPEN (2021) DOI / 10.1016/j.esmoop.2021.100062 Gold DOAJ, Green published

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Article Effect of aflibercept plus FOLFIRI and potential efficacy biomarkers in patients with metastatic colorectal cancer: the POLAF trial Elez, Elena; Auxiliadora Gomez-Espana, Maria; Gravalos, Cristina; Garcia-Alfonso, Pilar; Jose Ortiz-Morales, Maria; Losa, Ferran; Ales Diaz, Inmaculada; Grana, Begona; Toledano-Fonseca, Marta; Valladares-Ayerbes, Manuel; Polo, Eduardo; Salgado, Mercedes; M BRITISH JOURNAL OF CANCER (2021) DOI / 10.1038/s41416-021-01638-w

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Article Social support as predictor of anxiety and depression in cancer caregivers six months after cancer diagnosis: A longitudinal study Garcia-Torres, Francisco; Jablonski, Marcin Jacek; Gomez Solis, Angel; Antonio Moriana, Juan; Jose Jaen-Moreno, Maria; Jose Moreno-Diaz, Maria; Aranda, Enrique JOURNAL OF CLINICAL NURSING 0962-1067 (2020) DOI / 10.1111/jocn.15123