Trabajos de Rafael Franco

Pharmacology & Toxicology


  Listando 23 trabajos del autor/autora 38
Lista de trabajos en el área Pharmacology & Toxicology
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Article Cannabigerol Action at Cannabinoid CB1 and CB2 Receptors and at CB1-CB2 Heteroreceptor Complexes Navarro, Gemma; Varani, Katia; Reyes-Resina, Irene; Sanchez de Medina, Veronica; Rivas-Santisteban, Rafael; Sanchez-Carnerero Callado, Carolina; Vincenzi, Fabrizio; Casano, Salvatore; Ferreiro-Vera, Carlos; Canela, Enric, I; Borea, Pier Andrea; Nadals, Xav FRONTIERS IN PHARMACOLOGY (2018) DOI / 10.3389/fphar.2018.00632 Green published, Gold
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Article Pharmacological data of cannabidiol- and cannabigerol-type phytocannabinoids acting on cannabinoid CB1, CB2 and CB1/CB2 heteromer receptors Navarro, Gemma; Varani, Katia; Lillo, Alejandro; Vincenzi, Fabrizio; Rivas-Santisteban, Rafael; Raich, Iu; Reyes-Resina, Irene; Ferreiro-Vera, Carlos; Borea, Pier Andrea; Sanchez de Medina, Veronica; Nadal, Xavier; Franco, Rafael PHARMACOLOGICAL RESEARCH 1043-6618 (2020) DOI / 10.1016/j.phrs.2020.104940
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Article A First-in-Class Small-Molecule that Acts as a Dual Inhibitor of HDAC and PDE5 and that Rescues Hippocampal Synaptic Impairment in Alzheimer's Disease Mice Cuadrado-Tejedor, Mar; Garcia-Barroso, Carolina; Sanchez-Arias, Juan A.; Rabal, Obdulia; Perez-Gonzalez, Marta; Mederos, Sara; Ugarte, Ana; Franco, Rafael; Segura, Victor; Perea, Gertrudis; Oyarzabal, Julen; Garcia-Osta, Ana NEUROPSYCHOPHARMACOLOGY 0893-133X (2017) DOI / 10.1038/npp.2016.163 Bronze, Green published
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Review Dopamine in Health and Disease: Much More Than a Neurotransmitter Franco, Rafael; Reyes-Resina, Irene; Navarro, Gemma BIOMEDICINES (2021) DOI / 10.3390/biomedicines9020109 Gold DOAJ, Green published
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Article Molecular and functional interaction between GPR18 and cannabinoid CB2 G-protein-coupled receptors. Relevance in neurodegenerative diseases Reyes-Resina, Irene; Navarro, Gemma; Aguinaga, David; Canela, Enric I.; Schoeder, Clara T.; Zaluski, Michal; Kiec-Kononowicz, Katarzyna; Saura, Carlos A.; Mueller, Christa E.; Franco, Rafael BIOCHEMICAL PHARMACOLOGY 0006-2952 (2018) DOI / 10.1016/j.bcp.2018.06.001 Green accepted
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Review Antioxidants versus Food Antioxidant Additives and Food Preservatives Franco, Rafael; Navarro, Gemma; Martinez-Pinilla, Eva ANTIOXIDANTS (2019) DOI / 10.3390/antiox8110542 Gold DOAJ, Green published
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Article Cannabidiol skews biased agonism at cannabinoid CB1 and CB2 receptors with smaller effect in CB1-CB2 heteroreceptor complexes Navarro, Gemma; Reyes-Resina, Irene; Rivas-Santisteban, Rafael; Sanchez de Medina, Veronica; Morales, Paula; Casano, Salvatore; Ferreiro-Vera, Carlos; Lilo, Alejandro; Aguinaga, David; Jagerovic, Nadine; Nadal, Xavier; Franco, Rafael BIOCHEMICAL PHARMACOLOGY 0006-2952 (2018) DOI / 10.1016/j.bcp.2018.08.046
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Article Potent and Subtype-Selective Dopamine D-2 Receptor Biased Partial Agonists Discovered via an Ugi-Based Approach Mallo-Abreu, Ana; Reyes-Resina, Irene; Azuaje, Jhonny; Franco, Rafael; Garcia-Rey, Aitor; Majellaro, Maria; Miranda-Pastoriza, Dario; Garcia-Mera, Xerardo; Jespers, Willem; Gutierrez-de-Teran, Hugo; Navarro, Gemma; Sotelo, Eddy JOURNAL OF MEDICINAL CHEMISTRY 0022-2623 (2021) DOI / 10.1021/acs.jmedchem.1c00704 Hybrid, Green published
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Article Pharmacologic antagonism of dopamine receptor D3 attenuates neurodegeneration and motor impairment in a mouse model of Parkinson's disease Elgueta, Daniela; Aymerich, Maria S.; Contreras, Francisco; Montoya, Andro; Celorrio, Marta; Rojo-Bustamante, Estefania; Riquelme, Eduardo; Gonzalez, Hugo; Vasquez, Monica; Franco, Rafael; Pacheco, Rodrigo NEUROPHARMACOLOGY 0028-3908 (2017) DOI / 10.1016/j.neuropharm.2016.09.028
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Editorial Material Why have transgenic rodent models failed to successfully mimic Alzheimer's disease. How can we develop effective drugs without them? Franco, Rafael; Martinez-Pinilla, Eva; Navarro, Gemma EXPERT OPINION ON DRUG DISCOVERY 1746-0441 (2019) DOI / 10.1080/17460441.2019.1581169 Bronze
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Article Binding and Signaling Studies Disclose a Potential Allosteric Site for Cannabidiol in Cannabinoid CB2 Receptors Martinez-Pinilla, Eva; Varani, Katia; Reyes-Resina, Irene; Angelats, Edgar; Vincenzi, Fabrizio; Ferreiro-Vera, Carlos; Oyarzabal, Julen; Canela, Enric I.; Lanciego, Jose L.; Nadal, Xavier; Navarro, Gemma; Borea, Pier Andrea; Franco, Rafael FRONTIERS IN PHARMACOLOGY (2017) DOI / 10.3389/fphar.2017.00744 Green published, Gold
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Review Pharmacological potential of varinic-, minor-, and acidic phytocannabinoids Franco, Rafael; Rivas-Santisteban, Rafael; Reyes-Resina, Irene; Casanovas, Mireia; Perez-Olives, Catalina; Ferreiro-Vera, Carlos; Navarro, Gemma; Sanchez de Medina, Veronica; Nadal, Xavier PHARMACOLOGICAL RESEARCH 1043-6618 (2020) DOI / 10.1016/j.phrs.2020.104801
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Article GPR55: A therapeutic target for Parkinson's disease? Celorrio, Marta; Rojo-Bustamante, Estefania; Fernandez-Suarez, Diana; Saez, Elena; Estella-Hermoso de Mendoza, Ander; Mueller, Christa E.; Ramirez, Maria J.; Oyarzabal, Julen; Franco, Rafael; Aymerich, Maria S. NEUROPHARMACOLOGY 0028-3908 (2017) DOI / 10.1016/j.neuropharm.2017.08.017
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Article Alterations in Gene and Protein Expression of Cannabinoid CB2 and GPR55 Receptors in the Dorsolateral Prefrontal Cortex of Suicide Victims Garcia-Gutierrez, Maria S.; Navarrete, Francisco; Navarro, Gemma; Reyes-Resina, Irene; Franco, Rafael; Luis Lanciego, Jose; Giner, Salvador; Manzanares, Jorge NEUROTHERAPEUTICS 1933-7213 (2018) DOI / 10.1007/s13311-018-0610-y Bronze, Green published
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Review Increased expression of cannabinoid CB2 and serotonin 5-HT1A heteroreceptor complexes in a model of newborn hypoxic-ischemic brain damage Franco, Rafael; Villa, Maria; Morales, Paula; Reyes-Resina, Irene; Gutierrez-Rodriguez, Ana; Jimenez, Jasmina; Jagerovic, Nadine; Martinez-Orgado, Jose; Navarro, Gemma NEUROPHARMACOLOGY 0028-3908 (2019) DOI / 10.1016/j.neuropharm.2019.02.004
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Article Design of Negative and Positive Allosteric Modulators of the Cannabinoid CB2 Receptor Derived from the Natural Product Cannabidiol Navarro, Gemma; Gonzalez, Angel; Sanchez-Morales, Adria; Casajuana-Martin, Nil; Gomez-Ventura, Marc; Cordomi, Arnau; Busque, Felix; Alibes, Ramon; Pardo, Leonardo; Franco, Rafael JOURNAL OF MEDICINAL CHEMISTRY 0022-2623 (2021) DOI / 10.1021/acs.jmedchem.1c00561 Hybrid
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Article Novel Interactions Involving the Mas Receptor Show Potential of the Renin-Angiotensin system in the Regulation of Microglia Activation: Altered Expression in Parkinsonism and Dyskinesia Rivas-Santisteban, Rafael; Lillo, Jaume; Munoz, Ana; Rodriguez-Perez, Ana, I; Luis Labandeira-Garcia, Jose; Navarro, Gemma; Franco, Rafael NEUROTHERAPEUTICS 1933-7213 (2021) DOI / 10.1007/s13311-020-00986-4 Green published, Bronze
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Article Differential effect of amphetamine over the corticotropin-releasing factor CRF2 receptor, the orexin OX1 receptor and the CRF2-OX1 heteroreceptor complex Navarro, Gemma; Medrano, Mireia; Aguinaga, David; Vega-Quiroga, Ignacio; Lillo, Alejandro; Jimenez, Jasmina; Casanovas, Mireia; Canela, Enric I.; Mallol, Josefa; Gysling, Katia; Franco, Rafael NEUROPHARMACOLOGY 0028-3908 (2019) DOI / 10.1016/j.neuropharm.2018.11.014 Green accepted
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Article Carnitine palmitoyltransferase 1C negatively regulates the endocannabinoid hydrolase ABHD6 in mice, depending on nutritional status Miralpeix, Cristina; Reguera, Ana Cristina; Fosch, Anna; Casas, Maria; Lillo, Jaume; Navarro, Gemma; Franco, Rafael; Casas, Josefina; Alexander, Stephen P. H.; Casals, Nuria; Rodriguez-Rodriguez, Rosalia BRITISH JOURNAL OF PHARMACOLOGY 0007-1188 (2021) DOI / 10.1111/bph.15377 Gold other
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Article Similarities and differences upon binding of naturally occurring Delta(9)-tetrahydrocannabinol-derivatives to cannabinoid CB1 and CB2 receptors Raich, Iu; Rivas-Santisteban, Rafael; Lillo, Alejandro; Lillo, Jaume; Reyes-Resina, Irene; Nadal, Xavier; Ferreiro-Vera, Carlos; Sanchez de Medina, Veronica; Majellaro, Maria; Sotelo, Eddy; Navarro, Gemma; Franco, Rafael PHARMACOLOGICAL RESEARCH 1043-6618 (2021) DOI / 10.1016/j.phrs.2021.105970 Hybrid
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Review Hormetic and Mitochondria-Related Mechanisms of Antioxidant Action of Phytochemicals Franco, Rafael; Navarro, Gemma; Martinez-Pinilla, Eva ANTIOXIDANTS (2019) DOI / 10.3390/antiox8090373 Gold DOAJ, Green published
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Article A(2A) and A(2B) adenosine receptors: The extracellular loop 2 determines high (A(2A)) or low affinity (A(2B)) for adenosine De Filippo, Elisabetta; Hinz, Sonja; Pellizzari, Veronica; Deganutti, Giuseppe; El-Tayeb, Ali; Navarro, Gemma; Franco, Rafael; Moro, Stefano; Schiedel, Anke C.; Mueller, Christa E. BIOCHEMICAL PHARMACOLOGY 0006-2952 (2020) DOI / 10.1016/j.bcp.2019.113718
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Article The Old and New Visions of Biased Agonism Through the Prism of Adenosine Receptor Signaling and Receptor/Receptor and Receptor/Protein Interactions Franco, Rafael; Rivas-Santisteban, Rafael; Reyes-Resina, Irene; Navarro, Gemma FRONTIERS IN PHARMACOLOGY (2021) DOI / 10.3389/fphar.2020.628601 Green published, Gold

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