Seasonal coronavirus protective immunity is short-lasting
Edridge, Arthur W. D.; Kaczorowska, Joanna; Hoste, Alexis C. R.; Bakker, Margreet; Klein, Michelle; Loens, Katherine; Jebbink, Maarten F.; Matser, Amy; Kinsella, Cormac M.; Rueda, Paloma; Ieven, Margareta; Goossens, Herman; Prins, Maria; Sastre, Patricia;
NATURE MEDICINE
2020
VL / 26 - BP / 1691 - EP / +
abstract
A key unsolved question in the current coronavirus disease 2019 (COVID-19) pandemic is the duration of acquired immunity. Insights from infections with the four seasonal human coronaviruses might reveal common characteristics applicable to all human coronaviruses. We monitored healthy individuals for more than 35 years and determined that reinfection with the same seasonal coronavirus occurred frequently at 12 months after infection. The durability of immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is unknown. Lessons from seasonal coronavirus infections in humans show that reinfections can occur within 12 months of initial infection, coupled with changes in levels of virus-specific antibodies.
20th
Global
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3690 InfluRatio
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Bronze, Green submitted
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Molecular Biology & Genetics
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Biology & Biochemistry
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2 Twitter
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328 Wikipedia
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Clinical Medicine
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2 Twitter
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328 Wikipedia
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3.9K Policy
Global
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2 Twitter
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328 Wikipedia
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4 News
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3.9K Policy
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