Article LXR stimulates a metabolic switch and reveals cholesterol homeostasis as a statin target in Tasmanian devil facial tumor disease Ikonomopoulou, Maria P.; Lopez-Mancheno, Yaiza; Novelle, Marta G.; Martinez-Una, Maite; Gangoda, Lahiru; Pal, Martin; Filipe Costa-Machado, Luis; Jose Fernandez-Marcos, Pablo; Ramm, Grant A.; Alejandro Fernandez-Rojo, Manuel CELL REPORTS 2211-1247 (2021) DOI / 10.1016/j.celrep.2021.108851 OPEN ACCESS LEVEL / Gold DOAJ

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Article T cells with dysfunctional mitochondria induce multimorbidity and premature senescence Desdin-Mico, Gabriela; Soto-Heredero, Gonzalo; Francisco Aranda, Juan; Oller, Jorge; Carrasco, Elisa; Gabande-Rodriguez, Enrique; Maria Blanco, Eva; Alfranca, Arantzazu; Cusso, Lorena; Desco, Manuel; Ibanez, Borja; Gortazar, Arancha R.; Fernandez-Marcos, P SCIENCE 0036-8075 (2020) DOI / 10.1126/science.aax0860 OPEN ACCESS LEVEL / Green published

Biology & Biochemistry

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Article Restoration of energy homeostasis by SIRT6 extends healthy lifespan Roichman, A.; Elhanati, S.; Aon, M. A.; Abramovich, I; Di Francesco, A.; Shahar, Y.; Avivi, M. Y.; Shurgi, M.; Rubinstein, A.; Wiesner, Y.; Shuchami, A.; Petrover, Z.; Yaron, O.; Lyashkov, A.; Ubaida-Mohien, C.; Kanfi, Y.; Lerrer, B.; Fernandez-Marcos, P. NATURE COMMUNICATIONS (2021) DOI / 10.1038/s41467-021-23545-7 OPEN ACCESS LEVEL / Green published, Gold

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Article Sirt1 protects from K-Ras-driven lung carcinogenesis Filipe Costa-Machado, Luis; Martin-Hernandez, Roberto; Angel Sanchez-Luengo, Miguel; Hess, Katharina; Vales-Villamarin, Claudia; Barradas, Marta; Lynch, Cian; de la Nava, Daniel; Diaz-Ruiz, Alberto; de Cabo, Rafael; Canamero, Marta; Martinez, Lola; Sanchez EMBO REPORTS 1469-221X (2018) DOI / 10.15252/embr.201643879 OPEN ACCESS LEVEL / Bronze, Green published